Multi-stage concentrating and filtering device for drug intermediates

Abstract

The utility model relates to the technical field of medicine intermediate processing, and discloses a medicine intermediate multi-stage concentrating and filtering device which comprises a box body, two filtering frames are fixedly installed in the box body, filtering membranes are arranged in the filtering frames, impurity collecting openings extending out of the filtering frames are formed in the filtering frames, and the filtering membranes are arranged in the impurity collecting openings. A rotating shaft is rotationally connected into the box body, a threaded rod is rotated to drive a driving assembly to move, at the moment, a cleaning brush is not located in an impurity collecting opening any more, then a worker starts a first motor to drive a driving gear to rotate, and finally impurities on the surface of a filtering membrane are pushed into the impurity collecting opening; according to the concentration and filtration device for the drug intermediates, internal impurities can be cleaned by detaching the collecting frame by subsequent workers, the problem that the filtered impurities are inconvenient to clean by existing concentration and filtration devices for the drug intermediates is solved, the impurities are pushed into the impurity collecting opening through the cleaning brush, the impurities are subsequently collected through the collecting frame, and the operation is simple.

Description

Technical Field

[0001] The utility model relates to the technical field of drug intermediate processing, in particular to a drug intermediate multi-stage concentration and filtering device. Background Art

[0002] The so-called pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. Such chemical products do not require a drug production license and can be produced in ordinary chemical plants. As long as they reach a certain level, they can be used in the synthesis of drugs.

[0003] In the production process of pharmaceutical intermediates, since pharmaceutical intermediates contain a large amount of impurities, they need to be concentrated and filtered to remove the impurities before use. However, in some existing pharmaceutical intermediate concentration and filtration devices, the filtered macromolecular colloids and cellulose and other impurities will adhere to the surface of the filter membrane. After the concentration and filtration are completed, these impurities are not easy to clean up. If these impurities are not cleaned in time, the gaps on the surface of the filter membrane will be blocked, so that the filtration efficiency becomes low, and even some residual raw liquid will not be able to pass through the set filter membrane, affecting the normal concentration and filtration of the pharmaceutical intermediates. The practicability is low. In view of this, we propose a multi-stage concentration and filtration device for pharmaceutical intermediates to solve the above problems. Utility Model Content

[0004] 1. Technical issues to be resolved

[0005] In view of the deficiencies of the prior art, the utility model provides a multi-stage concentration and filtration device for a pharmaceutical intermediate, which solves the problem that some existing concentration and filtration devices for pharmaceutical intermediates are inconvenient for cleaning the impurities filtered out.

[0006] (II) Technical solution

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a multi-stage concentration and filtration device for pharmaceutical intermediates, comprising a box body, two filter frames are fixedly installed inside the box body, a filter membrane is arranged inside the filter frame, an impurity collection port extending to the outside is opened inside the filter frame, a rotating shaft is rotatably connected inside the box body, the upper end of the rotating shaft rotates and penetrates out of the box body, the filter frame is rotatably sleeved on the outer surface of the rotating shaft, the interior of the rotating shaft is hollow, a threaded rod is arranged inside the rotating shaft, the upper end of the threaded rod is threaded through the rotating shaft, a driving component is arranged on the outer surface of the threaded rod, and a sliding sleeve is arranged on the outer surface of the rotating shaft A sliding ring is provided, and an L-shaped connecting rod is fixedly connected to the outer surface of the sliding ring, and a triangular baffle is fixedly connected to the lower end of the L-shaped connecting rod, and a cleaning brush is arranged on the lower surface of the triangular baffle, and a collecting frame is arranged on the lower surface of the filter frame, and the collecting frame is located on the lower side of the impurity collecting port, and a first motor is fixedly connected to the upper surface of the box body, and a driving gear is fixedly connected to the output shaft of the first motor, and a driven gear is fixedly sleeved at one end of the rotating shaft located outside the box body, and the driven gear and the driving gear are meshingly connected, and a feed port is arranged on the upper side of the box body, and the feed port is communicated with the interior of the box body, and a door body is rotatably connected to the outer surface of the box body.

[0008] Preferably, the cleaning brush is located inside the impurity collection port, and the lower surface of the triangular baffle is adapted to the impurity collection port.

[0009] Preferably, the driving assembly includes a connecting rod, the upper end of the connecting rod and the lower end of the threaded rod are rotatably connected, the outer surface of the connecting rod is fixedly sleeved with a fixed block, the outer surface of the rotating shaft is provided with a sliding groove, the sliding groove is connected to the interior of the rotating shaft, the fixed block is slidably connected to the interior of the sliding groove, and the side surface of the fixed block away from the connecting rod is fixedly connected to the sliding ring.

[0010] Preferably, a second motor is fixedly connected to the outer surface of the box, and the output shaft of the second motor rotates and penetrates into the inside of the side wall of the box. A cavity is opened inside the side wall of the box, and two cams are arranged inside the box. The two cams are located between the two filter membranes, and the side surfaces of the two cams close to the second motor are fixedly connected to a rotating rod.

[0011] Preferably, the rotating rod is fixedly connected to the eccentric part of the cam, the end of the rotating rod away from the cam rotates through the interior of the side wall of the box body and is rotationally connected to the inner wall of the cavity, the upper rotating rod is fixedly connected to the output shaft of the second motor, and a transmission assembly is arranged inside the cavity.

[0012] Preferably, the transmission assembly includes two pulleys, and the two pulleys are respectively sleeved on the outer surfaces of the two rotating rods, and the outer surface transmission sleeves of the two pulleys are provided with belts.

[0013] (III) Beneficial effects

[0014] Compared with the prior art, the utility model provides a multi-stage concentration and filtration device for pharmaceutical intermediates, which has the following beneficial effects:

[0015] 1. The multi-stage concentration and filtration device for pharmaceutical intermediates drives the movement of the driving assembly by rotating the threaded rod. At this time, the cleaning brush will no longer be located inside the impurity collection port. Subsequently, the staff starts the first motor to drive the rotation of the driving gear, and finally pushes the impurities on the surface of the filter membrane into the inside of the impurity collection port. Subsequently, the staff can disassemble the collection frame to clean the impurities inside, which solves the problem that some existing pharmaceutical intermediate concentration and filtration devices are not convenient for cleaning the filtered impurities. The impurities are pushed into the inside of the impurity collection port by the cleaning brush, and then the impurities are collected by the collection frame. The operation is simple, and the cleaning can be achieved without the staff disassembling the filter frame and the filter membrane. The cleaning efficiency is high, and the situation where the impurities block the pores on the surface of the filter membrane is avoided as much as possible, thereby improving the filtration efficiency, ensuring the normal concentration and filtration, and having high practicality.

[0016] 2. The multi-stage concentration and filtration device for drug intermediates starts the second motor to drive the rotation of the upper rotating rod, and then guides the filter membrane through the rotation of the two cams, thereby finally achieving movement of the material on the surface of the filter membrane, thereby improving the filtration efficiency of the filter membrane, allowing the material to penetrate through the filter membrane faster, thereby improving the filtration efficiency and effect of the drug, and having high practicality. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the structure of a multi-stage concentration and filtration device for pharmaceutical intermediates of the utility model;

[0018] Figure 2 It is a cross-sectional schematic diagram of the box body of the utility model;

[0019] Figure 3 This is a schematic diagram of the structure of the filter frame of the utility model;

[0020] Figure 4 This is a schematic diagram of the structure of the sliding ring of the utility model;

[0021] Figure 5 This is a schematic diagram of the structure of the triangular baffle of the utility model;

[0022] Figure 6 It is a schematic diagram of the structure of the cavity of the utility model;

[0023] Figure 7 It is a structural schematic diagram of the cam of the utility model.

[0024] In the figure: 1. box body; 2. filter frame; 3. filter membrane; 4. impurity collection port; 5. rotating shaft; 6. sliding ring; 7. L-shaped connecting rod; 8. triangular baffle; 9. cleaning brush; 10. collecting frame; 11. first motor; 12. driving gear; 13. driven gear; 14. threaded rod; 15. connecting rod; 16. fixed block; 17. sliding groove; 18. second motor; 19. cavity; 20. cam; 21. rotating rod; 22. pulley; 23. belt; 24. feed port; 25. door body. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] See also Figure 1-Figure 7The utility model provides a technical solution: a multi-stage concentration and filtration device for pharmaceutical intermediates, including a box body 1, two filter frames 2 are fixedly installed inside the box body 1, a filter membrane 3 is arranged inside the filter frame 2, the pore sizes of the upper and lower filter membranes 3 are different, the pore size of the upper filter membrane 3 is larger than that of the lower filter membrane 3, thereby achieving the purpose of multi-stage filtration, an impurity collection port 4 extending to the outside is opened inside the filter frame 2, the inside of the box body 1 is rotatably connected with a rotating shaft 5, the upper end of the rotating shaft 5 rotates and penetrates out of the box body 1, the filter frame 2 is rotatably sleeved on the outer surface of the rotating shaft 5, the interior of the rotating shaft 5 is hollow, a threaded rod 14 is arranged inside the rotating shaft 5, the upper end of the threaded rod 14 is threadedly penetrated out of the rotating shaft 5, the outer surface of the threaded rod 14 is provided with a driving component, the outer surface of the rotating shaft 5 The sliding sleeve is provided with a sliding ring 6, and an L-shaped connecting rod 7 is fixedly connected to the outer surface of the sliding ring 6. A triangular baffle 8 is fixedly connected to the lower end of the L-shaped connecting rod 7. A cleaning brush 9 is provided on the lower surface of the triangular baffle 8. The cleaning brush 9 is located inside the impurity collecting port 4. The lower surface of the triangular baffle 8 is adapted to the impurity collecting port 4. A collecting frame 10 is provided on the lower surface of the filter frame 2. The collecting frame 10 is located on the lower side of the impurity collecting port 4. A first motor 11 is fixedly connected to the upper surface of the box body 1. A driving gear 12 is fixedly connected to the output shaft of the first motor 11. A driven gear 13 is fixedly provided at one end of the rotating shaft 5 located outside the box body 1. The driven gear 13 is meshed with the driving gear 12. When the staff needs to clean the impurities on the surface of the filter membrane 3, the driven gear 13 is meshed with the driving gear 12. Rotating the threaded rod 14 drives the movement of the driving assembly, and the driving assembly will drive the sliding ring 6 to slide on the outer surface of the rotating shaft 5, and the movement of the sliding ring 6 drives the movement of the L-shaped connecting rod 7, and the movement of the L-shaped connecting rod 7 drives the movement of the triangular baffle 8, and the movement of the triangular baffle 8 drives the movement of the cleaning brush 9. At this time, the cleaning brush 9 will no longer be located inside the impurity collecting port 4. Subsequently, the staff starts the first motor 11 to drive the rotation of the driving gear 12, and the rotation of the driving gear 12 drives the rotation of the driven gear 13, and the rotation of the rotating shaft 5 drives the rotation of the sliding ring 6, and the rotation of the L-shaped connecting rod 7 drives the rotation of the sliding ring 6. The rotation of the L-shaped connecting rod 7 drives The rotating triangular baffle 8 enables the cleaning brush 9 to slide on the surface of the filter membrane 3, and finally pushes the impurities on the surface of the filter membrane 3 into the impurity collecting port 4. At this time, the impurities will fall into the collecting frame 10. The staff can subsequently disassemble the collecting frame 10 to clean the impurities inside. The above structure solves the problem that some existing drug intermediate concentration and filtering devices are not convenient for cleaning the filtered impurities. The cleaning brush 9 pushes the impurities into the impurity collecting port 4, and the impurities are subsequently collected by the collecting frame 10. The operation is simple, and the staff does not need to disassemble the filter frame 2 and the filter membrane 3 to achieve cleaning. The cleaning efficiency is high, and the situation where impurities block the pores on the surface of the filter membrane 3 is avoided as much as possible, thereby improving the filtration efficiency.It ensures the normal concentration and filtration, and has high practicality.

[0027] Furthermore, the driving assembly includes a connecting rod 15, the upper end of the connecting rod 15 is rotatably connected to the lower end of the threaded rod 14, the outer surface of the connecting rod 15 is fixedly sleeved with a fixing block 16, the outer surface of the rotating shaft 5 is provided with a sliding groove 17, the sliding groove 17 is communicated with the interior of the rotating shaft 5, the fixing block 16 is slidably connected to the interior of the sliding groove 17, and the side surface of the fixing block 16 away from the connecting rod 15 is fixedly connected to the sliding ring 6. When the staff rotates the threaded rod 14, because the threaded rod 14 is threadedly sleeved inside the rotating shaft 5, the rotation of the threaded rod 14 will drive the movement of the connecting rod 15, and the movement of the connecting rod 15 will drive the fixing block 16 to slide inside the sliding groove 17. At this time, the connecting rod 15 will not rotate with the rotation of the threaded rod 14, and the movement of the fixing block 16 will drive the movement of the sliding ring 6. At this time, the sliding ring 6 will still block the sliding groove 17, thereby finally causing the cleaning brush 9 to rise, and the cleaning work can be carried out subsequently.

[0028] Furthermore, a second motor 18 is fixedly connected to the outer surface of the box body 1, and the output shaft of the second motor 18 rotates and penetrates into the interior of the side wall of the box body 1. A cavity 19 is opened inside the side wall of the box body 1, and two cams 20 are arranged inside the box body 1. The two cams 20 are located between the two filter membranes 3. The side surfaces of the two cams 20 close to the second motor 18 are fixedly connected with a rotating rod 21, and the rotating rod 21 is fixedly connected to the eccentric point of the cam 20. The end of the rotating rod 21 away from the cam 20 rotates and penetrates into the interior of the side wall of the box body 1 and is rotatably connected to the inner wall of the cavity 19. The upper rotating rod 21 is fixedly connected to the output shaft of the second motor 18, and a transmission assembly is arranged inside the cavity 19.

[0029] Furthermore, the transmission assembly includes two pulleys 22, and the two pulleys 22 are respectively sleeved on the outer surfaces of the two rotating rods 21. The outer surface transmission sleeves of the two pulleys 22 are provided with belts 23. The staff starts the second motor 18 to drive the upper rotating rod 21 to rotate. At this time, the transmission through the pulleys 22 and the belt 23 will drive the lower rotating rod 21 to rotate synchronously. The rotation of the two rotating rods 21 will respectively drive the rotation of the two cams 20. The rotation of the two cams 20 allows the filter membrane 3 to be guided, and finally the material on the surface of the filter membrane 3 is moved. The above structure improves the filtration efficiency of the filter membrane 3, so that the material can penetrate through the filter membrane 3 faster, thereby improving the filtration efficiency and effect of the drug, and the practicability is high.

[0030] Furthermore, a feed port 24 is provided on the upper side of the box body 1 , the feed port 24 is communicated with the interior of the box body 1 , and a door body 25 is rotatably connected to the outer surface of the box body 1 .

[0031] Working principle:

[0032] When the drug intermediate multi-stage concentration and filtration device is in use, the threaded rod 14 is rotated to drive the movement of the driving assembly. At this time, the driving assembly drives the sliding ring 6 to slide on the outer surface of the rotating shaft 5, and the movement of the sliding ring 6 drives the movement of the L-shaped connecting rod 7, and the movement of the L-shaped connecting rod 7 drives the movement of the triangular baffle 8, and the movement of the triangular baffle 8 drives the movement of the cleaning brush 9. At this time, the cleaning brush 9 will no longer be located inside the impurity collecting port 4. Subsequently, the staff starts the first motor 11 to drive the rotation of the driving gear 12, and the rotation of the driving gear 12 drives the rotation of the driven gear 13, and the rotation of the rotating shaft 5 is driven by the rotation of the driven gear 13. The rotation of the rotating shaft 5 drives the rotation of the sliding ring 6, the rotation of the L-shaped connecting rod 7, and the rotation of the triangular baffle 8, thereby realizing the sliding of the cleaning brush 9 on the surface of the filter membrane 3, and finally pushing the impurities on the surface of the filter membrane 3 into the inside of the impurity collecting port 4. At this time, the impurities will fall into the inside of the collecting frame 10, and the staff will subsequently disassemble the collecting frame 10 to clean the impurities inside.

[0033] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A multi-stage concentration and filtration device for pharmaceutical intermediates, comprising a housing (1), characterized in that: Two filter frames (2) are fixedly installed inside the housing (1), a filter membrane (3) is arranged inside the filter frame (2), an impurity collection port (4) extending to the outside is opened inside the filter frame (2), a rotating shaft (5) is rotatably connected inside the housing (1), the upper end of the rotating shaft (5) rotates through the housing (1), the filter frame (2) is rotatably sleeved on the outer surface of the rotating shaft (5), the interior of the rotating shaft (5) is hollow, a threaded rod (14) is arranged inside the rotating shaft (5), the upper end of the threaded rod (14) is threaded through the rotating shaft (5), a driving assembly is arranged on the outer surface of the threaded rod (14), and a sliding ring (14) is slidably sleeved on the outer surface of the rotating shaft (5) 6), an L-shaped connecting rod (7) is fixedly connected to the outer surface of the sliding ring (6), a triangular baffle (8) is fixedly connected to the lower end of the L-shaped connecting rod (7), a cleaning brush (9) is arranged on the lower surface of the triangular baffle (8), a collecting frame (10) is arranged on the lower surface of the filter frame (2), the collecting frame (10) is located at the lower side of the impurity collecting port (4), a first motor (11) is fixedly connected to the upper surface of the box body (1), an output shaft of the first motor (11) is fixedly connected to a driving gear (12), and a driven gear (13) is fixedly sleeved on one end of the rotating shaft (5) located outside the box body (1), and the driven gear (13) and the driving gear (12) are meshingly connected.

2. A multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 1, characterized in that: The cleaning brush (9) is located inside the impurity collection port (4), and the lower surface of the triangular baffle (8) is adapted to the impurity collection port (4).

3. A multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 1, characterized in that: The driving assembly comprises a connecting rod (15), the upper end of the connecting rod (15) is rotatably connected to the lower end of the threaded rod (14), a fixing block (16) is fixedly sleeved on the outer surface of the connecting rod (15), a sliding groove (17) is provided on the outer surface of the rotating shaft (5), the sliding groove (17) is connected to the inside of the rotating shaft (5), the fixing block (16) is slidably connected to the inside of the sliding groove (17), and a side surface of the fixing block (16) away from the connecting rod (15) is fixedly connected to the sliding ring (6).

4. A multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 1, characterized in that: A second motor (18) is fixedly connected to the outer surface of the box body (1), and an output shaft of the second motor (18) rotates and penetrates into the interior of the side wall of the box body (1). A cavity (19) is provided inside the side wall of the box body (1). Two cams (20) are arranged inside the box body (1), and the two cams (20) are located between the two filter membranes (3). A rotating rod (21) is fixedly connected to the surface of one side of the two cams (20) close to the second motor (18).

5. A multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 4, characterized in that: The rotating rod (21) is fixedly connected to the eccentric portion of the cam (20); one end of the rotating rod (21) away from the cam (20) rotates to penetrate into the interior of the side wall of the box body (1) and is rotatably connected to the inner wall of the cavity (19).

6. A multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 5, characterized in that: The rotating rod (21) on the upper side is fixedly connected to the output shaft of the second motor (18), and a transmission assembly is arranged inside the cavity (19).

7. A multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 6, characterized in that: The transmission assembly comprises two pulleys (22), the two pulleys (22) are respectively sleeved on the outer surfaces of the two rotating rods (21), and the outer surfaces of the two pulleys (22) are sleeved with belts (23).

8. The multi-stage concentration and filtration device for pharmaceutical intermediates according to claim 5, characterized in that: The upper side of the box body (1) is provided with a feed inlet (24), the feed inlet (24) is communicated with the interior of the box body (1), and the outer surface of the box body (1) is rotatably connected with a door body (25).

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