A kind of sitagliptin intermediate system treatment kettle

Abstract

The utility model discloses a sitagliptin intermediate system processing kettle, including a processing kettle, a foot is fixedly installed on the outer surface of the lower end of the processing kettle, a constant pressure relief valve is fixedly installed on one side of the outer surface of the upper end of the processing kettle, and a stirring component is fixedly installed in the middle of the outer surface of the upper end of the processing kettle, and the stirring component includes a mounting shell, an air pipe joint, a motor, a spiral blade, a one-way exhaust valve, an air guide pipe, an agitator, a driven shaft, a cavity, a rotary joint, a worm gear and a worm. The sitagliptin intermediate system processing kettle described in the utility model has a stirring component, which is convenient for stirring materials in different directions through the spiral blades and the agitator, thereby improving the efficiency and quality of stirring. The air pipe joint, the rotary joint, the driven shaft with a cavity, the air guide pipe and the one-way exhaust valve are convenient for aeration at the bottom of the inner cavity of the processing kettle, thereby further improving the efficiency of production.

Description

Technical Field

[0001] The utility model relates to the technical field of drug production equipment, in particular to a sitagliptin intermediate system reaction processing kettle. Background Art

[0002] Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that can be used as a glucose-lowering drug for type 2 diabetes.

[0003] In the process of producing sitagliptin, a processing kettle is required. In the prior art, the stirring structure used in the processing kettle is generally a motor driving a stirring paddle to rotate, and the material is stirred by the stirring paddle. The material can only be stirred in one direction by only using a stirring paddle, and the mixing effect is poor, thereby reducing the production quality and efficiency.

[0004] To this end, we proposed a process for the synthesis of sitagliptin intermediates. Utility Model Content

[0005] 1. Technical issues to be resolved

[0006] In view of the deficiencies in the prior art, the utility model provides a sitagliptin intermediate action processing kettle, which is convenient for stirring materials from different directions inside the processing kettle, improves the efficiency and quality of stirring, and can effectively solve the problems in the background technology.

[0007] (II) Technical solution

[0008] To achieve the above-mentioned purpose, the technical solution adopted by the utility model is: a sitagliptin intermediate system action processing kettle, including a processing kettle, a lower end outer surface of the processing kettle is fixedly installed with a support foot, a side of the upper end outer surface of the processing kettle is fixedly installed with a constant pressure relief valve, and the middle part of the upper end outer surface of the processing kettle is fixedly installed with a stirring assembly, the stirring assembly includes a mounting shell, an air pipe joint, a motor, a spiral blade, a one-way exhaust valve, an air guide pipe, a stirrer, a driven shaft, a cavity, a rotary joint, a worm gear and a worm, and the mounting shell is fixedly installed in the middle part of the upper end outer surface of the processing kettle.

[0009] Preferably, the motor is fixedly mounted on the outer surface of one end of the mounting shell, the trachea joint is fixedly mounted on the middle part of the outer surface of the upper end of the mounting shell, the worm gear, worm and rotary joint are all located inside the mounting shell, and the rotary joint is connected between the upper outer surface of the driven shaft and the lower outer surface of the trachea joint.

[0010] Preferably, the worm is connected to the outer surface of one end of the output shaft in the motor, the worm wheel is located on the outer surface of one side of the worm, and the worm wheel is fixedly mounted on the outer wall of the upper part of the driven shaft, the cavity is opened inside the driven shaft, the air duct is fixedly mounted on the bottom of the outer surfaces on both sides of the driven shaft, and the one-way exhaust valve is fixedly mounted on the outer surface of one side of the air duct.

[0011] Preferably, the spiral blades and the agitator are fixedly mounted on the outer wall of the lower part of the driven shaft.

[0012] Preferably, a sealed bearing is provided between the driven shaft and the processing kettle, and the driven shaft is rotatably connected to the processing kettle through the sealed bearing. The air guide pipe is located at the bottom of the inner cavity of the processing kettle, and a sealed bearing is provided between the driven shaft and the mounting shell, and the driven shaft is rotatably connected to the mounting shell through the sealed bearing.

[0013] Preferably, an outer surface of one side of the worm is meshed with an outer surface of one side of the worm wheel, a sealed bearing is provided between the worm and the mounting housing, the worm is rotatably connected to the mounting housing via the sealed bearing, a coupling is provided between the worm and the motor, and an outer surface of one end of the worm is fixedly connected to an outer surface of one end of an output shaft in the motor via the coupling.

[0014] (III) Beneficial effects

[0015] Compared with the prior art, the utility model provides a sitagliptin intermediate system reaction treatment kettle, which has the following beneficial effects:

[0016] 1. The sitagliptin intermediate production and processing kettle is provided with a stirring assembly, which facilitates stirring of materials in different directions through the provided spiral blades and agitator, thereby improving the efficiency and quality of stirring.

[0017] 2. The sitagliptin intermediate system treatment kettle is convenient for aeration at the bottom of the inner cavity of the treatment kettle through the arranged air pipe joint, rotary joint, driven shaft with a cavity, air guide pipe and one-way exhaust valve, thereby further improving production efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the overall structure of a sitagliptin intermediate processing kettle of the utility model.

[0019] Figure 2 This is a schematic structural diagram of a stirring component in a sitagliptin intermediate production process kettle of the utility model.

[0020] Figure 3 This utility model is a kind of sitagliptin intermediate system processing kettle Figure 2 Enlarged view of point A in the middle.

[0021] Figure 4 It is a side cross-sectional view of a shell installed in a sitagliptin intermediate processing kettle of the utility model.

[0022] In the figure: 1. treatment kettle; 2. support foot; 3. constant pressure relief valve; 4. stirring assembly; 5. mounting shell; 6. air pipe joint; 7. motor; 8. spiral blade; 9. one-way exhaust valve; 10. air guide tube; 11. agitator; 12. driven shaft; 13. cavity; 14. rotary joint; 15. worm gear; 16. worm. DETAILED DESCRIPTION

[0023] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0024] This embodiment is a sitagliptin intermediate system processing kettle.

[0025] like Figure 1-4 As shown, it includes a processing kettle 1, a support foot 2 is fixedly installed on the outer surface of the lower end of the processing kettle 1, a constant pressure relief valve 3 is fixedly installed on one side of the outer surface of the upper end of the processing kettle 1, and a stirring component 4 is fixedly installed in the middle of the outer surface of the upper end of the processing kettle 1. The stirring component 4 includes a mounting shell 5, an air pipe joint 6, a motor 7, a spiral blade 8, a one-way exhaust valve 9, an air guide pipe 10, an agitator 11, a driven shaft 12, a cavity 13, a rotary joint 14, a worm gear 15 and a worm 16. The mounting shell 5 is fixedly installed in the middle of the outer surface of the upper end of the processing kettle 1.

[0026] The motor 7 is fixedly mounted on the outer surface of one end of the mounting shell 5, the air pipe joint 6 is fixedly mounted on the middle of the outer surface of the upper end of the mounting shell 5, the worm gear 15, the worm 16 and the rotary joint 14 are all located inside the mounting shell 5, and the rotary joint 14 is connected between the upper outer surface of the driven shaft 12 and the lower outer surface of the air pipe joint 6; the worm 16 is connected to the outer surface of one end of the output shaft in the motor 7, the worm gear 15 is located on the outer surface of one side of the worm 16, and the worm gear 15 is fixedly mounted on the outer wall of the upper part of the driven shaft 12, the cavity 13 is opened inside the driven shaft 12, the air guide pipe 10 is fixedly mounted on the bottom of the outer surfaces of both sides of the driven shaft 12, and the one-way exhaust valve 9 is fixedly mounted on the outer surface of one side of the air guide pipe 10; the spiral blade 8, the stirrer 11 is fixedly mounted on the outer wall of the lower part of the driven shaft 12; a sealed bearing is arranged between the driven shaft 12 and the processing kettle 1, and the driven shaft 12 is rotatably connected to the processing kettle 1 through the sealed bearing; the air guide pipe 10 is located at the bottom of the inner cavity of the processing kettle 1; a sealed bearing is arranged between the driven shaft 12 and the mounting shell 5, and the driven shaft 12 is rotatably connected to the mounting shell 5 through the sealed bearing; the outer surface of one side of the worm 16 is meshed with the outer surface of one side of the worm wheel 15, a sealed bearing is arranged between the worm 16 and the mounting shell 5, and the worm 16 is rotatably connected to the mounting shell 5 through the sealed bearing; a coupling is arranged between the worm 16 and the motor 7, and the outer surface of one end of the worm 16 is fixedly connected to the outer surface of one end of the output shaft in the motor 7 through the coupling.

[0027] It should be noted that the utility model is a sitagliptin intermediate system processing kettle. The processing kettle 1 recorded in the text belongs to the prior art and can be effectively known to the technicians in the relevant technical field, and the details are not repeated here. The stirring assembly 4 is set, and the worm 16 is driven by the operation of the motor 7 to rotate. The worm 16 and the worm wheel 15 are meshed with each other. The worm 16 drives the driven shaft 12 to rotate through the worm wheel 15. The driven shaft 12 drives the spiral blade 8 and the agitator 11 to rotate. The operation of the spiral blade 8 can drive the inner cavity of the processing kettle 1 The material moves in the vertical direction, and the material can be stirred in the horizontal direction through the agitator 11. The spiral blades 8 and the agitator 11 can improve the production efficiency and quality; the air pipe joint 6 is connected to the air supply device, and the air pipe joint 6 is connected to the driven shaft 12 through a rotary joint 14 (a rotary joint refers to: a pipeline connecting device, and the connected pipelines can rotate relatively, and can be used to transmit various media such as gas, liquid, oil, etc.), and the gas is discharged through the position of the one-way exhaust valve 9, which is convenient for aeration at the bottom of the inner cavity of the processing kettle 1, thereby further improving the production efficiency.

[0028] It should be noted that, in this article, relational terms such as first and second (number one, number two), etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "including one..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0029] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. The technicians in this industry should understand that the utility model is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model will have various changes and improvements, and these changes and improvements fall within the scope of the utility model to be protected.

Claims

1. A sitagliptin intermediate production process kettle, comprising a process kettle (1), characterized in that: A support foot (2) is fixedly mounted on the outer surface of the lower end of the processing kettle (1); a constant pressure relief valve (3) is fixedly mounted on one side of the outer surface of the upper end of the processing kettle (1); a stirring assembly (4) is fixedly mounted in the middle of the outer surface of the upper end of the processing kettle (1); the stirring assembly (4) comprises a mounting shell (5), an air pipe joint (6), a motor (7), a spiral blade (8), a one-way exhaust valve (9), an air guide pipe (10), an agitator (11), a driven shaft (12), a cavity (13), a rotary joint (14), a worm gear (15) and a worm (16); the mounting shell (5) is fixedly mounted in the middle of the outer surface of the upper end of the processing kettle (1).

2. A sitagliptin intermediate system reaction kettle according to claim 1, characterized in that: The motor (7) is fixedly mounted on the outer surface of one end of the mounting shell (5); the air pipe joint (6) is fixedly mounted on the middle part of the outer surface of the upper end of the mounting shell (5); the worm wheel (15), the worm (16) and the rotary joint (14) are all located inside the mounting shell (5); and the rotary joint (14) is connected between the outer surface of the upper end of the driven shaft (12) and the outer surface of the lower end of the air pipe joint (6).

3. A sitagliptin intermediate system reaction kettle according to claim 2, characterized in that: The worm (16) is connected to the outer surface of one end of the output shaft of the motor (7); the worm wheel (15) is located on the outer surface of one side of the worm (16); and the worm wheel (15) is fixedly mounted on the outer wall of the upper part of the driven shaft (12); the cavity (13) is opened inside the driven shaft (12); the air guide pipe (10) is fixedly mounted on the bottom of the outer surfaces of both sides of the driven shaft (12); and the one-way exhaust valve (9) is fixedly mounted on the outer surface of one side of the air guide pipe (10).

4. A sitagliptin intermediate system reaction kettle according to claim 3, characterized in that: The spiral blade (8) and the stirrer (11) are fixedly mounted on the outer wall of the lower part of the driven shaft (12).

5. A sitagliptin intermediate system reaction kettle according to claim 4, characterized in that: A sealed bearing is provided between the driven shaft (12) and the processing kettle (1), and the driven shaft (12) is rotatably connected to the processing kettle (1) via the sealed bearing; the air guide pipe (10) is located at the bottom of the inner cavity of the processing kettle (1); a sealed bearing is provided between the driven shaft (12) and the mounting shell (5), and the driven shaft (12) is rotatably connected to the mounting shell (5) via the sealed bearing.

6. A sitagliptin intermediate system reaction kettle according to claim 5, characterized in that: An outer surface of one side of the worm (16) meshes with an outer surface of one side of the worm wheel (15); a sealed bearing is provided between the worm (16) and the mounting housing (5); the worm (16) is rotationally connected to the mounting housing (5) via the sealed bearing; a coupling is provided between the worm (16) and the motor (7); an outer surface of one end of the worm (16) is fixedly connected to an outer surface of one end of an output shaft in the motor (7) via the coupling.

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