In-vitro diagnosis microsphere lens assembly

By designing an in vitro diagnostic microsphere lens assembly including a coarse precision sliding table, a medium-precision sliding table and a high-precision adjustment column, combined with the microsphere lens probe assembly, the problem that the microsphere lens assembly cannot be accurately focused and positioned in the prior art is solved, and high-resolution imaging and flexible operation are achieved.

CN222887732UActive Publication Date: 2025-05-20SHAOXING YUANHE BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421766779.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-24
Publication Date
2025-05-20
Estimated Expiration
2034-07-24

AI Technical Summary

Technical Problem

Existing microsphere lens components cannot be accurately focused and positioned, calibrated and controlled, difficult to maintain and troubleshoot, and the microsphere position is random, limiting the application of super-resolution microscopy imaging technology.

Method used

An in vitro diagnostic microsphere lens assembly was designed to achieve precise control and focus of the microsphere lens by setting up a coarse precision sliding table, a medium-precision sliding table and a high-precision adjustment column; at the same time, a microsphere lens probe assembly, including a circular fixed column, a movable cylinder, a threaded column and a telescopic probe, realize the rotation and movement of the microsphere lens, and enhance the flexibility of imaging operation.

Benefits of technology

It realizes the precise position and focus control of the microsphere lens, obtains high-resolution images, is simple in structure, easy to operate and maintain, and has a wide range of application prospects.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model belongs to the technical field of in-vitro diagnosis microsphere lens assemblies, and particularly relates to an in-vitro diagnosis microsphere lens assembly which comprises a support, a coarse precision adjusting sliding table is fixedly installed on the outer wall of the support, a medium precision adjusting sliding table is fixedly installed on the outer wall of the coarse precision adjusting sliding table, and the medium precision adjusting sliding table is fixedly installed on the outer wall of the medium precision adjusting sliding table. And a fixing frame is fixedly installed on the outer wall of the middle-precision sliding adjusting table, a mounting plate is slidably connected to the outer wall of the fixing frame, and a supporting plate is fixedly installed on the upper side of the mounting plate. According to the in-vitro diagnosis microsphere lens assembly, by arranging the coarse-precision adjusting sliding table, the medium-precision adjusting sliding table and the high-precision adjusting column, the position and focusing of the microsphere lens can be accurately controlled, and therefore a high-resolution image is obtained; by arranging the microballoon lens probe assembly, rotation and movement of the microballoon lens can be accurately controlled, so that more flexible imaging operation is realized; meanwhile, the device is simple in structure and easy to operate and maintain, and has wide application prospects.
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Description

Technical Field

[0001] The utility model relates to the technical field of in vitro diagnostic microsphere lens assemblies, and specifically relates to an in vitro diagnostic microsphere lens assembly. Background Art

[0002] As an important means in in vitro diagnosis, optical imaging technology has the advantages of non-invasiveness, real-time performance, and high resolution. In the field of biomedicine, optical imaging technology is widely used in multiple aspects such as cell observation, tissue analysis, and pathogen detection. These technologies usually rely on optical instruments such as optical microscopes and spectrometers to obtain diagnostic information by capturing and analyzing the optical signals of samples.

[0003] Currently, the existing microsphere lens assemblies cannot perform precise focusing and positioning, cannot be precisely calibrated and controlled, and are difficult to maintain and troubleshoot. There are also some limitations in the microsphere lens super-resolution microscopy technology, such as the randomness of the microsphere position. In order to overcome this limitation, in view of this, an in vitro diagnostic microsphere lens assembly is proposed. Summary of the Utility Model

[0004] The main purpose of the utility model is to provide an in vitro diagnostic microsphere lens assembly, which can solve the problems proposed in the above background art.

[0005] To achieve the above purpose, the in vitro diagnostic microsphere lens assembly proposed by the utility model includes a bracket. A rough-precision adjustment stage is fixedly installed on the outer wall of the bracket. A medium-precision adjustment stage is fixedly installed on the outer wall of the rough-precision adjustment stage. A fixing frame is fixedly installed on the outer wall of the medium-precision adjustment stage. A mounting plate is slidably connected to the outer wall of the fixing frame. A support plate is fixedly installed on the upper side of the mounting plate. A high-precision adjustment column is fixedly installed on the upper side of the support plate, and the lower side of the high-precision adjustment column abuts against the upper side of the fixing frame. A microsphere lens probe assembly is arranged on the outer wall of the mounting plate. The microsphere lens probe assembly includes:

[0006] A circular fixing column, one end of which is clamped on the outer wall of the mounting plate, and the other end of which is fixedly connected to a fixing block;

[0007] A movable cylinder, which penetrates the fixing block and is rotatably connected to the fixing block. A threaded hole is provided on the outer wall of the movable cylinder. A fixing column is fixedly connected to the outer wall of the movable cylinder. One end of the fixing column away from the movable cylinder is hinged to an outer sleeve rod, and a telescopic probe is sleeved at the end of the outer sleeve rod away from the fixing column;

[0008] A threaded column, which penetrates the fixing block and is threadedly connected to the fixing block.

[0009] Preferably, a storage table is fixedly installed on the outer wall of the bracket, and a high-precision cross slide is arranged on the outer wall of the storage table, which can achieve two-dimensional precise movement in the plane.

[0010] Preferably, a plurality of threaded holes are formed in the outer wall of the movable cylinder, and the plurality of threaded holes are distributed in a circumferential array of the movable cylinder, enhancing the connection flexibility.

[0011] Preferably, an optical colloid is arranged on the outer wall of the high-precision cross slide, and a microsphere lens is arranged below the optical colloid. The optical colloid usually has excellent light transmittance, refractive index and optical stability.

[0012] Preferably, the threaded column penetrates through the fixing block and is threadedly connected to the fixing block, and the threaded column is threadedly connected to the threaded hole.

[0013] Preferably, a storage table is arranged on the right side of the rough precision adjustment slide.

[0014] The utility model provides an in vitro diagnostic microsphere lens assembly. It has the following beneficial effects:

[0015] (1) By setting a rough precision adjustment slide, a medium precision adjustment slide and a high-precision adjustment column, the in vitro diagnostic microsphere lens assembly can accurately control the position and focusing of the microsphere lens, so as to obtain high-resolution images; by setting a microsphere lens probe assembly, the rotation and movement of the microsphere lens can be accurately controlled, so as to realize more flexible imaging operations; at the same time, the device has a simple structure, is easy to operate and maintain, and has a wide application prospect.

[0016] (2) By setting a movable cylinder and threaded holes, the in vitro diagnostic microsphere lens assembly can finely adjust and fix the telescopic probe, improving the stability and precision of the probe. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present utility model. For those of ordinary skill in the art, other drawings can be obtained based on the structures shown in these drawings without creative efforts.

[0018] Figure 1 It is a three-dimensional structure schematic diagram of the present utility model;

[0019] Figure 2 It is a structural schematic diagram of the microsphere lens probe assembly of the present utility model;

[0020] Figure 3 For the present utility model Figure 3Schematic diagram of structure A

[0021] Explanation of reference numerals in the attached drawings:

[0022] 1. Bracket; 2. Coarse-precision adjustment slide; 3. Medium-precision adjustment slide; 4. Fixed bracket; 5. Mounting plate; 6. Support plate; 7. High-precision adjustment column; 8. Microsphere lens probe assembly; 9. Object table; 10. High-precision cross slide; 11. Optical colloid; 81. Circular fixed column; 82. Fixed block; 83. Threaded hole; 84. Movable cylinder; 85. Threaded column; 86. Fixed column; 87. Outer sleeve rod; 88. Telescopic probe

[0023] The realization of the purpose, functional features and advantages of the present utility model will be further described with reference to the embodiments and the accompanying drawings. Specific embodiments

[0024] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0025] Please refer to Figures 1 - 3 , the present utility model provides an in vitro diagnostic microsphere lens assembly, including a bracket 1. An object table 9 is fixedly installed on the outer wall of the bracket 1. A high-precision cross slide 10 is arranged on the outer wall of the object table 9. An optical colloid 11 is arranged on the outer wall of the high-precision cross slide 10. A microsphere lens is arranged in the optical colloid 11 to achieve a finer imaging effect. A coarse-precision adjustment slide 2 is fixedly installed on the outer wall of the bracket 1, which is used to realize the preliminary positioning adjustment of the microsphere lens probe assembly 8 within a large range and improve the efficiency of subsequent adjustment. An object table 9 is arranged on the right side of the coarse-precision adjustment slide 2. A medium-precision adjustment slide 3 is fixedly installed on the outer wall of the coarse-precision adjustment slide 2 to further refine the adjustment accuracy and ensure that the microsphere lens probe assembly 8 can approach the target area. A fixed bracket 4 is fixedly installed on the outer wall of the medium-precision adjustment slide 3 to provide a stable support platform for the subsequent precision adjustment system. An installation plate 5 is slidably connected to the outer wall of the fixed bracket 4. A support plate 6 is fixedly installed on the upper side of the installation plate 5. A high-precision adjustment column 7 is fixedly installed on the upper side of the support plate 6, and the lower side of the high-precision adjustment column 7 abuts against the upper side of the fixed bracket 4. The precise height adjustment of the installation plate 5 and its upper components is realized by the expansion and contraction of the adjustment column. A microsphere lens probe assembly 8 is arranged on the outer wall of the installation plate 5.

[0026] Further, the microsphere lens probe assembly 8 includes a circular fixing post 81. One end of the circular fixing post 81 is clamped on the outer wall of the mounting plate 5, and the other end of the circular fixing post 81 is fixedly connected with a fixing block 82, providing a stable foundation for the entire probe assembly. The movable cylinder 84 passes through the fixing block 82 and is rotatably connected to the fixing block 82. Threaded holes 83 are formed on the outer wall of the movable cylinder 84. A plurality of groups of threaded holes 83 are formed on the outer wall of the movable cylinder 84, and the plurality of groups of threaded holes 83 are distributed in a circumferential array around the movable cylinder 84, enhancing the flexibility and adjustability of the connection. The threaded post 85 passes through the fixing block 82 and is threadedly connected to the fixing block 82, for fixing the position of the movable cylinder 84 to ensure the stability after adjustment. A fixing post 86 is fixedly connected to the outer wall of the movable cylinder 84. A fixing post 86 is also fixedly connected to the outer wall of the movable cylinder 84, for connecting subsequent components. One end of the fixing post 86 away from the movable cylinder 84 is hinged to an outer sleeve rod 87, and a telescopic probe 88 is sleeved on the end of the outer sleeve rod 87 away from the fixing post 86. This design enables the telescopic probe 88 to flexibly expand and contract and rotate in three-dimensional space, and can precisely control the rotation and movement of the microsphere lens, thereby realizing a more flexible imaging operation.

[0027] In the present utility model, during use, first, the rough-precision adjustment slide table 2 is used to perform a large-range preliminary positioning on the entire microsphere lens assembly to quickly approach the target area and improve the starting efficiency of subsequent adjustment. Then, the medium-precision adjustment slide table 3 is used to further refine the adjustment of the microsphere lens probe assembly 8 to ensure that the microsphere lens probe assembly 8 can approach the target position more accurately, laying a foundation for precise adjustment. Through the telescopic function of the high-precision adjustment column 7, the height of the mounting plate 5 and the microsphere lens probe assembly 8 is precisely controlled to achieve micron-level vertical displacement adjustment. Rotate the threaded post 85 to make it rotate in the threaded hole 83, thereby fixing or releasing the movable cylinder 84. With the multiple threaded holes 83 distributed in a circumferential array around the movable cylinder 84, different fixing positions can be selected according to needs, increasing the flexibility of adjustment. Through the hinge design of the outer sleeve rod 87 and the fixing post 86, and the telescopic function of the telescopic probe 88, the angle and position of the probe can be flexibly adjusted in three-dimensional space to achieve precise rotation and movement of the microsphere lens.

[0028] The above are only the preferred embodiments of the present utility model, and do not limit the patent scope of the present utility model accordingly. Any equivalent structural transformation made under the inventive concept of the present utility model by using the content of the specification and drawings of the present utility model, or any direct / indirect application in other related technical fields, is included in the patent protection scope of the present utility model.

Claims

1. An in vitro diagnostic microsphere lens assembly, comprising a support (1), characterized in that: A coarse precision adjustment slide (2) is fixedly mounted on the outer wall of the bracket (1), a medium precision adjustment slide (3) is fixedly mounted on the outer wall of the coarse precision adjustment slide (2), a fixing frame (4) is fixedly mounted on the outer wall of the medium precision adjustment slide (3), a mounting plate (5) is slidably connected to the outer wall of the fixing frame, a support plate (6) is fixedly mounted on the upper side of the mounting plate (5), a high precision adjustment column (7) is fixedly mounted on the upper side of the support plate (6), and the lower side of the high precision adjustment column (7) abuts against the upper side of the fixing frame (4), and a microsphere lens probe assembly (8) is arranged on the outer wall of the mounting plate (5), and the microsphere lens probe assembly (8) comprises: A circular fixing column (81), one end of which is clamped on the outer wall of the mounting plate (5), and the other end of which is fixedly connected to a fixing block (82); A movable cylinder (84), the movable cylinder (84) passes through the fixed block (82) and is rotatably connected to the fixed block (82), a threaded hole (83) is provided on the outer wall of the movable cylinder (84), a fixed column (86) is fixedly connected to the outer wall of the movable cylinder (84), an outer sleeve rod (87) is hinged at one end of the fixed column (86) away from the movable cylinder (84), and a telescopic probe (88) is sleeved at one end of the outer sleeve rod (87) away from the fixed column (86); A threaded column (85) passes through the fixing block (82) and is threadedly connected to the fixing block (82).

2. The in vitro diagnostic microsphere lens assembly according to claim 1, characterized in that: A storage platform (9) is fixedly mounted on the outer wall of the bracket (1), and a high-precision cross slide (10) is arranged on the outer wall of the storage platform (9).

3. The in vitro diagnostic microsphere lens assembly according to claim 1, characterized in that: A plurality of groups of threaded holes (83) are provided on the outer wall of the movable cylinder (84), and the plurality of groups of threaded holes (83) are distributed in a circumferential array around the movable cylinder (84).

4. The in vitro diagnostic microsphere lens assembly according to claim 2, characterized in that: An optical colloid (11) is arranged on the outer wall of the high-precision cross slide (10), and a microsphere lens is arranged below the optical colloid (11).

5. The in vitro diagnostic microsphere lens assembly according to claim 3, characterized in that: The threaded column (85) passes through the fixing block (82) and is threadedly connected to the fixing block (82), and the threaded column (85) is threadedly connected to the threaded hole (83).

6. The in vitro diagnostic microsphere lens assembly according to claim 1, characterized in that: A storage platform (9) is arranged on the right side of the coarse precision adjustment slide platform (2).