Ovarian tissue freezing device

Abstract

The utility model discloses an ovarian tissue freezing device which comprises a bearing mechanism and a freezing mechanism, the bearing mechanism comprises a pipe cover, a loading plate and a baffle, the top of the pipe cover is fixedly connected with a handheld handle, the bottom of the pipe cover is fixedly connected with a first connecting plate, one end of the first connecting plate is rotatably connected with a second connecting plate, and the other end of the first connecting plate is rotatably connected with the baffle. The ovarian tissue fixing device has the advantages that the ovarian tissue can be loaded on the loading plate, the baffle and the loading plate can be closed to extrude and fix the ovarian tissue, the elastic piece connected between the first connecting plate and the second connecting plate can be reset, and the reset second connecting plate and the first connecting plate can be in an upright state; ovarian tissue loaded by the loading plate can be put into the freezing pipe, liquid nitrogen stored in the freezing pipe can freeze the ovarian tissue, the structure is reasonable, ovarian tissue storage is safe and reliable, the utilization rate is high, and economy and convenience are achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of ovarian tissue cryopreservation, in particular to an ovarian tissue cryopreservation device. Background Art

[0002] With the progress of medical technology and more and more user-friendly treatment methods, the survival period of cancer patients has been significantly extended. At the same time, the demand for fertility among more and more cancer patients has increased significantly. However, radiotherapy and chemotherapy during cancer treatment have brought great damage to the fertility of patients, seriously affecting their reproductive function and quality of life. Therefore, fertility preservation has become an issue that doctors and patients pay more and more attention to.

[0003] Currently, there are mainly three ways to preserve fertility in reproductive centers, namely gamete cryopreservation, embryo cryopreservation, and ovarian tissue cryopreservation. Gamete and embryo cryopreservation are very mature technologies and are currently the most common methods of fertility preservation.

[0004] Ovarian tissue cryopreservation is carried out by vitrification. After the ovarian tissue is processed, it is cut into skin slices of 10mm x 10mm x 1mm. The skin slices are processed in a commercial equilibration solution and cryoprotectant solution, and then the processed ovarian skin slices are placed on a cryopreservation carrier, and then the cryopreservation carrier containing the ovarian tissue is placed in liquid nitrogen for storage. In this process, the cryopreservation carrier is one of the key factors for the success of ovarian tissue cryopreservation. The Chinese utility model patent with the authorization announcement number CN219182562U provides a clamping device for ovarian tissue cryopreservation. The tissue slices can be fixed in the cryopreservation carrier by the first and second clamping nets being flipped and stacked, effectively avoiding the problem of falling off. However, this form of flipping and folding greatly reduces the loading capacity of a single carrier under the same volume, and the effective utilization rate is low. At the same time, the overly dense mesh structure may also cause irreversible damage to the antral follicles on the ovarian cortex. More importantly, this upright device requires a very large amount of thawing solution during later thawing, resulting in a waste of medical resources and an increased burden on patients.

[0005] In summary, there is an urgent need for an ovarian tissue cryopreservation device to solve the above problems. Summary of the Utility Model

[0006] To solve the above problems, the utility model provides an ovarian tissue cryopreservation device, and the utility model is realized through the following technical solutions.

[0007] An ovarian tissue freezing device includes a carrying mechanism and a freezing mechanism. The carrying mechanism includes a tube cap, a loading plate, and a baffle. A handhold is fixedly connected to the top of the tube cap. A first connecting plate is fixedly connected to the bottom of the tube cap. One end of the first connecting plate is rotatably connected to a second connecting plate. Through holes are formed on the outer surface of the loading plate. A convex block, a rotating frame, and a first limiting block are fixedly connected to the top of the loading plate. Connecting holes and connecting blocks are respectively arranged at both ends of the bottom of the baffle. A baffle handle and a second limiting block are respectively fixedly connected to both ends of the baffle. The freezing mechanism includes a freezing tube.

[0008] Further, the freezing tube is in threaded fit with the tube cap.

[0009] Further, an annular sealing ring is embedded and connected inside the [relevant part], and the tube cap is hermetically connected to the freezing tube through the annular sealing ring.

[0010] Further, a notch is formed at one end of the first connecting plate. A shaft rod penetrating through one end of the second connecting plate rotates in the notch. A spring piece is fixedly connected between the first connecting plate and the second connecting plate. The loading plate is fixedly connected to the other end of the second connecting plate.

[0011] Further, the baffle is rotatably connected to the rotating frame through the connecting hole. The connecting block is embedded and connected inside a connecting groove formed on the outer surface of the second connecting plate. Hemispherical clamping grooves are formed on both sides of the connecting block. Hemispherical clamping blocks formed inside the connecting groove are embedded and connected to the hemispherical clamping grooves.

[0012] Further, the baffle is pressed above the loading plate, and the gap between the loading plate and the baffle is 0.5 - 1 mm, and the rotation angle between the loading plate and the baffle is 0 - 120°.

[0013] The beneficial effects of the present utility model are as follows: During the working process of the device, by pressing down the handhold with hand, the loading plate in contact with the desktop can drive the connected second connecting plate to rotate on the first connecting plate until the loading plate is horizontally placed on the desktop. Then, by pulling the baffle handle to drive the baffle to rotate on the loading plate, the baffle and the loading plate can be rotated and opened. After opening, ovarian tissue can be loaded onto the loading plate. After loading, the baffle and the loading plate are closed again to squeeze and fix the ovarian tissue. Finally, the pressing on the handhold is released, and the spring piece connected between the first connecting plate and the second connecting plate can be reset. After resetting, the second connecting plate and the first connecting plate can be in an upright state, so that the ovarian tissue loaded on the loading plate can be placed inside the freezing tube, and the liquid nitrogen stored inside the freezing tube can freeze it. The structure is reasonable, making the storage of ovarian tissue safe, reliable, highly utilized, economical, and convenient. Description of the Drawings

[0014] To more clearly illustrate the technical solution of the present utility model, the following will briefly introduce the drawings required for use in the description of the specific implementation manners. Obviously, the drawings in the following description are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0015] Figure 1 : Structural schematic diagram of an ovarian tissue freezing device described in the present utility model;

[0016] Figure 2 : Connection schematic diagram of the first connecting plate and the second connecting plate of the present utility model;

[0017] Figure 3 : Structural schematic diagram of the loading plate of the present utility model;

[0018] Figure 4 : Partial structural schematic diagram of the baffle of the present utility model.

[0019] The reference numerals are as follows:

[0020] 1. Freezing tube;

[0021] 2. Tube cap; 21. Hand-held handle; 22. First connecting plate; 221. Notch; 23. Second connecting plate; 231. Shaft rod; 232. Connecting groove; 233. Hemispherical clamping block;

[0022] 3. Elastic sheet;

[0023] 4. Loading plate; 41. Through hole; 42. Convex block; 43. Rotating frame; 44. First limiting block;

[0024] 5. Baffle; 51. Connecting hole; 52. Connecting block; 521. Hemispherical clamping groove; 53. Baffle handle; 54. Second limiting block. Specific implementation manners

[0025] The following will clearly and completely describe the technical solutions in the embodiments of the present utility model in conjunction with the drawings in the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, rather than all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present utility model.

[0026] As Figures 1-4 shown, the present utility model has the following specific embodiments.

[0027] Embodiment:

[0028] An ovarian tissue freezing device includes a carrying mechanism and a freezing mechanism. The carrying mechanism includes a tube cap 2, a loading plate 4, and a baffle 5. A hand-held handle 21 is fixedly connected to the top of the tube cap 2. A first connecting plate 22 is fixedly connected to the bottom of the tube cap 2. One end of the first connecting plate 22 is rotatably connected to a second connecting plate 23. Through holes 41 are formed on the outer surface of the loading plate 4. A convex block 42, a rotating frame 43, and a first limiting block 44 are fixedly connected to the top of the loading plate 4. Connecting holes 51 and connecting blocks 52 are respectively arranged at both ends of the bottom of the baffle 5. A baffle handle 53 and a second limiting block 54 are respectively fixedly connected to both ends of the baffle 5. The freezing mechanism includes a freezing tube 1.

[0029] By adopting the above technical solution, when using the device, press down by holding the hand-held handle 21, so that the loading plate 4 in contact with the desktop can drive the connected second connecting plate 23 to rotate on the first connecting plate 22 until the loading plate 4 is horizontally placed on the desktop. Then pull the baffle handle 53 to drive the baffle 5 to rotate on the loading plate 4, so that the baffle 5 and the loading plate 4 can be rotated and opened. After opening, ovarian tissue can be loaded onto the loading plate 4. After loading, use the baffle 5 and the loading plate 4 to close, so as to squeeze and fix the ovarian tissue. Finally, release the pressure on the hand-held handle 21, and the elastic piece 3 connected between the second connecting plate 23 and the first connecting plate 22 can be reset. After resetting, the second connecting plate 23 and the first connecting plate 22 can be in an upright state, so that the ovarian tissue loaded on the loading plate 4 can be put into the freezing tube 1. The liquid nitrogen stored in the freezing tube 1 can freeze it. The structure is reasonable, making the storage of ovarian tissue safe, reliable, highly utilized, economical and convenient.

[0030] Specifically, the freezing tube 1 and the tube cap 2 are in threaded fit;

[0031] An annular sealing ring is embedded in the tube cap 2, and the tube cap 2 is hermetically connected to the freezing tube 1 through the annular sealing ring.

[0032] By adopting the above technical solution, the set tube cap 2 can be in threaded fit with the freezing tube 1, which is convenient for disassembling and assembling the freezing tube 1 and the tube cap 2, and convenient for putting the loading plate 4 loaded with ovarian tissue into and taking out of the freezing tube 1. At the same time, the annular sealing ring embedded in the tube cap 2 can make the connection between it and the freezing tube 1 have better sealing performance.

[0033] Specifically, a notch 221 is formed at one end of the first connecting plate 22. A shaft rod 231 penetrating through one end of the second connecting plate 23 rotates in the notch 221. An elastic piece 3 is fixedly connected between the first connecting plate 22 and the second connecting plate 23. The loading plate 4 is fixedly connected to the other end of the second connecting plate 23.

[0034] By adopting the above technical solution, the second connecting plate 23 can be rotatably connected in the notch 221 formed in the first connecting plate 22 through the provided shaft rod 231, and the elastic sheet 3 provided between the first connecting plate 22 and the second connecting plate 23 can keep their connection horizontal. When the second connecting plate 23 is extruded by an external force, it can rotate, facilitating the rotation of the second connecting plate 23 when holding the handle 21 by hand, driving the connected loading plate 4 to be laid flat, so as to facilitate loading ovarian tissue on the loading plate 4.

[0035] Specifically, the baffle 5 is rotatably connected to the rotating frame 43 through the connection hole 51, the connecting block 52 is embedded and connected inside the connection groove 232 formed on the outer surface of the second connecting plate 23, hemispherical clamping grooves 521 are formed on both sides of the connecting block 52, and the hemispherical clamping blocks 233 formed inside the connection groove 232 are embedded and connected with the hemispherical clamping grooves 521.

[0036] By adopting the above technical solution, the baffle 5 can rotate by being sleeved on the rotating frame 43 through the provided connection hole 51, and the connecting block 52 connected to the baffle 5 can be inserted into the connection groove 232 formed in the second connecting plate 23 for docking. Among them, the hemispherical clamping block 233 fixed inside the connection groove 232 can be clamped in the hemispherical clamping groove 521 formed on the connecting block 52, so as to facilitate the positioning and fixing of the rotatable baffle 5 and the loading plate 4.

[0037] Specifically, the baffle 5 is pressed above the loading plate 4, the gap between the loading plate 4 and the baffle 5 is 0.5 - 1 mm, and the rotation angle between the loading plate 4 and the baffle 5 is 0 - 120°.

[0038] By adopting the above technical solution, the provided baffle 5 can squeeze the ovarian tissue on the loading plate 4, avoiding the shedding of ovarian tissue. At the same time, the loading plate 4 and the baffle 5 can rotate between 1° and 120°, facilitating opening, and facilitating the loading and taking out of ovarian tissue.

[0039] The above - disclosed preferred embodiments of the present invention are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the present invention to only the specific implementation manners. Obviously, according to the content of this specification, many modifications and changes can be made. This specification selects and specifically describes these embodiments to better explain the principle and practical application of the present invention, so that those skilled in the relevant technical field can well understand and utilize the present invention. The present invention is only limited by the claims and their full scope and equivalents.

Claims

1. An ovarian tissue freezing device, comprising a bearing mechanism and a freezing mechanism, characterized in that: The bearing mechanism comprises a tube cover (2), a loading plate (4) and a baffle (5); the top of the tube cover (2) is fixedly connected to a hand-held handle (21); the bottom of the tube cover (2) is fixedly connected to a first connecting plate (22); one end of the first connecting plate (22) is rotatably connected to a second connecting plate (23); a through hole (41) is provided on the outer surface of the loading plate (4); a convex block (42), a rotating frame (43) and a first limit block (44) are fixedly connected to the top of the loading plate (4); a connecting hole (51) and a connecting block (52) are respectively provided at both ends of the bottom of the baffle (5); and a baffle handle (53) and a second limit block (54) are respectively fixedly connected at both ends of the baffle (5); and the freezing mechanism comprises a freezing tube (1).

2. An ovarian tissue freezing device according to claim 1, characterized in that: The freezing tube (1) and the tube cover (2) are threadedly matched.

3. An ovarian tissue freezing device according to claim 2, characterized in that: An annular sealing ring is embedded and connected inside the (2), and the tube cover (2) is sealed and connected to the freezing tube (1) via the annular sealing ring.

4. The ovarian tissue freezing device according to claim 1, characterized in that: A notch (221) is formed at one end of the first connecting plate (22), a shaft (231) passing through one end of the second connecting plate (23) rotates in the notch (221), a spring sheet (3) is fixedly connected between the first connecting plate (22) and the second connecting plate (23), and the loading plate (4) is fixedly connected to the other end of the second connecting plate (23).

5. The ovarian tissue freezing device according to claim 1, characterized in that: The baffle (5) is rotatably connected to the rotating frame (43) via a connecting hole (51); the connecting block (52) is embedded in a connecting groove (232) provided on the outer surface of the second connecting plate (23); hemispherical clamping grooves (521) are provided on both sides of the connecting block (52); and the hemispherical clamping block (233) provided in the connecting groove (232) is embedded in and connected to the hemispherical clamping groove (521).

6. The ovarian tissue freezing device according to claim 4, characterized in that: The baffle plate (5) is pressed onto the top of the loading plate (4), and the gap between the loading plate (4) and the baffle plate (5) is 0.5-1 mm, and the rotation angle between the loading plate (4) and the baffle plate (5) is 0-120°.

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