Auxiliary fixing device for mouse tracheal injection
By designing a mouse tracheal injection assisted fixation device, the glottis is found using support plates and adjustable fixation units, which solves the problem of laryngoscopic fixation instability and improves the success rate and safety of intratracheal injection.
Patent Information
- Application Number
- CN202421688678.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-17
- Publication Date
- 2025-07-22
- Estimated Expiration
- 2034-07-17
AI Technical Summary
In the prior art, during intratracheal injection of mice, laryngoscopy is difficult to fix, resulting in uneven visual field, increasing the risk of tongue damage and injection failure, and affecting the success rate of operation.
A mouse tracheal injection auxiliary fixation device is designed, including a support plate, a fixing mechanism and a fixing belt. The mouse's trachea is fixed through a fixing unit, and the adjustable fixing unit is used to find the glottis to expand the field of view and avoid blind insertion to damage the oral mucosa.
It improves the success rate of intratracheal injection, reduces pain and tongue damage in mice, and ensures the accuracy and safety of the operation.
Smart Images

Figure CN223126691U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the field of detection, and particularly relates to an auxiliary fixing device for tracheal injection of mice. Background Technique
[0002] Non-invasive operation in the trachea can effectively reduce the trauma of experimental animals and relieve their pain. At present, the non-invasive injection method in the trachea mostly exposes the glottis of mice through a laryngoscope and performs tracheal injection. However, the stress points of the laryngoscope are uneven. During the actual operation, the tongue body of the mouse needs to bear more pressure, often causing damage and bleeding of the tongue body, increasing the pain of experimental animals and affecting the exposure of the field of view under the laryngoscope. In addition, since it is difficult to fix the laryngoscope in the throat of mice, it cannot successfully guide the head of the tracheal injection device to accurately enter the trachea, resulting in the failure of tracheal injection. Summary of the Invention
[0003] In view of this, the utility model aims to overcome the defects in the prior art and proposes an auxiliary fixing device for tracheal injection of mice.
[0004] To achieve the above object, the technical solution of the utility model is realized as follows:
[0005] An auxiliary fixing device for tracheal injection of mice, comprising a support plate, a fixing mechanism and a fixing belt. The fixing mechanism and the fixing belt are both located on the support plate, and the fixing mechanism is located on one side of the fixing belt;
[0006] The fixing mechanism includes a fixing unit and two fixing blocks. The fixing unit is located between the fixing blocks, and the fixing unit is connected to the fixing blocks respectively through elastic ropes.
[0007] Further, the fixing unit includes an outer telescopic body, an inner fixing body, an inner telescopic body, an outer fixing body and a limiting unit. The outer fixing body is sleeved outside the inner fixing body. One end of the inner fixing body is located inside the outer telescopic body and is matched with the outer telescopic body. One end of the inner telescopic body is located inside the inner fixing body and is matched with the inner fixing body. The limiting unit is located on the outer fixing body and is matched with the inner telescopic body. The fixing unit cooperates with the elastic rope to fix the front teeth of the mouse. At the same time, the telescopic fixing unit can be used to broaden the field of view, facilitate injection, and prevent the operator from blindly inserting, thereby damaging the oral mucosa of the mouse.
[0008] Further, the outer fixing body and the outer telescopic body are respectively located at both ends of the inner fixing body.
[0009] Further, the limiting unit includes a driving rod, a limiting seat, and a buffer block. The limiting seat is located on the outer fixing body. The driving rod is rotatably connected to the limiting seat. One end of the driving rod is provided with a limiting rod, which cooperates with the inner telescopic body. The buffer block is located on the outer fixing body, and the buffer block and the limiting rod are respectively located at both ends of the driving rod. The outer limiting body can be lifted relative to the inner fixing body, and the inner telescopic body can be lifted relative to the inner fixing body.
[0010] Further, limiting holes are provided at both ends of the inner telescopic body, and the limiting holes cooperate with the limiting rod. When the operator presses the driving rod inward, the limiting rod can be inserted into the limiting hole to limit the inner telescopic body. When the driving rod is lifted, the limiting rod can be lifted out of the limiting hole, and the movement of the inner telescopic body can be realized.
[0011] Further, two connecting blocks are provided on the outer fixing body, and the connecting blocks are connected to the corresponding fixing blocks through elastic ropes.
[0012] Further, limiting platforms are provided on the outer sides of the top and bottom of the inner telescopic body, limiting platforms are provided on the outer side of the top of the inner fixing body and on the inner side of the bottom, and a limiting platform is provided on the inner side of the bottom of the outer telescopic body. The outer diameters of the top limiting platform and the bottom limiting platform of the inner telescopic body are both larger than the inner diameter of the bottom limiting platform of the inner fixing body, and the bottom limiting platform of the inner fixing body is used to limit the inner telescopic body; the inner diameter of the bottom limiting platform of the outer telescopic body is smaller than the outer diameter of the top limiting platform of the inner fixing body, and the inner telescopic body is used to limit the outer telescopic body.
[0013] Compared with the prior art, the present utility model has the following advantages:
[0014] The mouse tracheal injection auxiliary fixing device of the present utility model is provided with a fixing unit. First, the trachea of the mouse is fixed through the fixing unit, and then the glottis is found by adjusting the length of the fixing unit, thereby improving the success rate of injection. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] The drawings forming a part of the present utility model are used to provide a further understanding of the present utility model. The schematic embodiments of the present utility model and their descriptions are used to explain the present utility model and do not constitute an improper limitation to the present utility model. In the drawings:
[0016] Figure 1 is a schematic diagram of the mouse tracheal injection auxiliary fixing device according to an embodiment of the present utility model;
[0017] Figure 2 is a schematic diagram of the fixing mechanism (initial state) according to an embodiment of the present utility model;
[0018] Figure 3 Schematic diagram of the fixing mechanism (injection state) described in the embodiments of the present utility model.
[0019] Description of the reference numerals:
[0020] 1. Support plate; 2. Fixing mechanism; 3. Fixing belt; 21. Fixing unit; 22. Elastic drawstring; 23. Fixing block; 211. Outer telescopic body; 212. Inner fixing body; 213. Inner telescopic body; 2131. Limiting hole; 214. Outer fixing body; 2141. Connecting block; 215. Limiting unit; 2151. Driving rod; 2152. Limiting seat; 2153. Limiting rod; 2154. Buffer block. Detailed implementation manners
[0021] It should be noted that, without conflict, the embodiments in the present utility model and the features in the embodiments may be combined with each other.
[0022] In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present utility model. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, the features defined with "first", "second", etc. may explicitly or implicitly include one or more of such features. In the description of the present utility model, unless otherwise specified, the meaning of "a plurality" is two or more.
[0023] In the description of the present utility model, it should be noted that, unless otherwise clearly defined and limited, the terms "installed", "connected", "connected" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected, or indirectly connected through an intermediate medium, and it may be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood through specific situations.
[0024] The present utility model will be described in detail below with reference to the drawings and in combination with the embodiments.
[0025] As Figures 1-3As shown in the figure, a mouse tracheal injection auxiliary fixing device includes a support plate 1, a fixing mechanism 2, and a fixing belt 3. The fixing mechanism 2 and the fixing belt 3 are both located on the support plate 1, and the fixing mechanism 2 is located on one side of the fixing belt 3. The fixing mechanism 2 includes a fixing unit 21 and two fixing blocks 23. The fixing unit 21 is located between the fixing blocks 23, and the fixing unit 21 is connected to the fixing blocks 23 respectively through elastic ropes 22.
[0026] The fixing unit 21 includes an outer telescopic body 211, an inner fixing body 212, an inner telescopic body 213, an outer fixing body 214, and a limiting unit 215. The outer fixing body 214 is sleeved outside the inner fixing body 212. One end of the inner fixing body 212 is located inside the outer telescopic body 211 and is matched with the outer telescopic body 211. One end of the inner telescopic body 213 is located inside the inner fixing body 212 and is matched with the inner fixing body 212. The limiting unit 215 is located on the outer fixing body 214 and is matched with the inner telescopic body 213. The fixing unit 21 cooperates with the elastic rope 22 to fix the front teeth of the mouse. At the same time, the telescopic fixing unit 21 can be used to widen the field of view, facilitate injection, and prevent the operator from blindly inserting, thereby damaging the oral mucosa of the mouse. The outer fixing body 214 and the outer telescopic body 211 are respectively located at the ends of the inner fixing body 212.
[0027] The limiting unit 215 includes a driving rod 2151, a limiting seat 2152, and a buffer block 2154. The limiting seat 2152 is located on the outer fixing body 214. The driving rod 2151 is rotatably connected to the limiting seat 2152. One end of the driving rod 2151 is provided with a limiting rod 2153, and the limiting rod 2153 is matched with the inner telescopic body 213. The buffer block 2154 is located on the outer fixing body 214, and the buffer block 2154 and the limiting rod 2153 are respectively located at both ends of the driving rod 2151. The outer limiting body can be lifted relative to the inner fixing body 212, and the inner telescopic body 213 can be lifted relative to the inner fixing body 212. Both ends of the inner telescopic body 213 are provided with limiting holes 2131, and the limiting holes 2131 are matched with the limiting rod 2153. When the operator presses the driving rod 2151 inward, the limiting rod 2153 can be inserted into the limiting hole 2131 to realize the limitation of the inner telescopic body 213. When the driving rod 2151 is lifted, the limiting rod 2153 can be lifted out of the limiting hole 2131, and the movement of the inner telescopic body 213 can be realized. Two connecting blocks 2141 are arranged on the outer fixing body 214, and the connecting blocks 2141 are connected to the corresponding fixing blocks 23 through the elastic ropes 22.
[0028] Limit platforms are provided on both the top and the outer side of the bottom of the inner telescopic body 213. Limit platforms are provided on the outer side of the top and the inner side of the bottom of the inner fixing body 212. A limit platform is provided on the inner side of the bottom of the outer telescopic body 211. The outer diameters of the top limit platform and the bottom limit platform of the inner telescopic body 213 are both larger than the inner diameter of the bottom limit platform of the inner fixing body 212, and the bottom limit platform of the inner fixing body 212 is used to limit the inner telescopic body 213; the inner diameter of the bottom limit platform of the outer telescopic body 211 is smaller than the outer diameter of the top limit platform of the inner fixing body 212, and the inner telescopic body 213 is used to limit the outer telescopic body 211.
[0029] Implementation process:
[0030] First, fix the mouse body at a specified position through the fixing belt 3, then open the mouse's mouth, lift the fixing unit 21 through the elastic pull cord 22, place it in the mouse's mouth, open the mouse's mouth by pulling the mouse's teeth, lift the driving rod 2151, move the limiting rod 2153 out of the limiting hole 2131, then push the inner telescopic body 213 inward from the inside to move it into the mouse's mouth, then press the driving rod 2151 to insert the limiting rod 2153 into the limiting hole 2131 at the top of the inner telescopic rod. At this time, the glottis can be observed through the inner telescopic rod. Then lift the outer telescopic body 211 and move it upward to facilitate expanding the field of view. At this time, injection can be carried out.
[0031] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.
Claims
1. A mouse tracheal injection auxiliary fixation device, characterized in that: It includes a support plate, a fixing mechanism, and a fixing belt. The fixing mechanism and the fixing belt are both located on the support plate, and the fixing mechanism is located on one side of the fixing belt. The fixing mechanism includes a fixing unit and two fixing blocks. The fixing unit is located between the fixing blocks, and the fixing unit is connected to the fixing blocks respectively through elastic drawstrings. The fixing unit includes an outer telescopic body, an inner fixing body, an inner telescopic body, an outer fixing body, and a limiting unit. The outer fixing body is sleeved outside the inner fixing body. One end of the inner fixing body is located inside the outer telescopic body and is matched with the outer telescopic body. One end of the inner telescopic body is located inside the inner fixing body and is matched with the inner fixing body. The limiting unit is located on the outer fixing body and is matched with the inner telescopic body. The limiting unit includes a driving rod, a limiting seat, and a buffer block. The limiting seat is located on the outer fixing body. The driving rod is rotatably connected to the limiting seat. A limiting rod is provided at one end of the driving rod. The limiting rod is matched with the inner telescopic body. The buffer block is located on the outer fixing body. The buffer block and the limiting rod are respectively located at both ends of the driving rod.
2. The mouse tracheal injection assistance fixation device according to claim 1, wherein: The outer fixing body and the outer telescopic body are respectively located at both ends of the inner fixing body.
3. The mouse tracheal injection auxiliary fixation device according to claim 1, characterized in that: Limit holes are provided at both ends of the inner telescopic body, and the limit holes are matched with the limiting rods.
4. The mouse tracheal injection auxiliary fixing device according to claim 1, wherein: Two connecting blocks are provided on the outer fixing body, and the connecting blocks are connected to the corresponding fixing blocks through the elastic drawstrings.
5. The mouse tracheal injection auxiliary fixing device according to claim 1, wherein: Limit platforms are provided on both the top and bottom outsides of the inner telescopic body, limit platforms are provided on the top outside and bottom inside of the inner fixing body, and a limit platform is provided on the bottom inside of the outer telescopic body.