Stem cell exosome freeze-dried powder packaging bottle

Abstract

The utility model relates to the technical field of biotechnology, and discloses a stem cell exosome freeze-dried powder packaging bottle which comprises a packaging bottle body, the packaging bottle body is composed of a storage bottle and a mixing bottle, built-in bottles are symmetrically arranged in the storage bottle, a sealing ring is fixed outside a bottle opening of the storage bottle, and a sealing cover is connected outside the sealing ring in a sealing mode. Movable holes are symmetrically formed in the top of the sealing cover, piston rods are movably installed in the movable holes, one ends of the piston rods extend into the built-in bottle and are connected with sealing plugs, and flow guide openings are symmetrically fixed to the bottom end of the inner wall of the storage bottle. The storage bottle and the mixing bottle are arranged to be of an integrated structure, the storage bottle provides outer layer protection for freeze-dried powder, the mixing bottle is used for mixing freeze-dried powder raw materials, through the arrangement of the built-in bottle, during daily placement, the sealing plug is located in the sealing cavity for sealing, a multi-layer sealing space is formed, air, moisture and light are effectively prevented from entering, and the freeze-dried powder is prevented from entering the mixing bottle. The sealing protection can greatly protect the activity and stability of the freeze-dried powder.

Description

Technical Field

[0001] This application relates to the field of biotechnology, and particularly to a freeze-dried powder packaging bottle for stem cell exosomes. Background Art

[0002] In the field of biotechnology, stem cell exosomes have become a research hotspot in recent years due to their unique biological activities and potential therapeutic values. As an important medium for intercellular communication, stem cell exosomes are widely used in multiple aspects such as disease treatment, tissue repair, and regenerative medicine. Currently, the common preservation method for stem cell exosomes on the market mostly adopts freeze-drying technology to make them into freeze-dried powder form to extend the preservation period and maintain their biological activities. However, most of the existing freeze-dried powder packaging bottles are composed of simple glass bottles and sealing caps, and they mostly have disadvantages such as poor sealing performance, strong light transmittance, and the material is prone to react with the freeze-dried powder. These problems may all lead to a decrease in the activity or failure of stem cell exosomes during storage, seriously affecting their subsequent application effects.

[0003] Moreover, under normal circumstances, the storage and mixing of freeze-dried powder require the use of different containers respectively, and the operation is relatively cumbersome, resulting in being easily affected by external factors during the transfer process, reducing the activity and stability of the freeze-dried powder.

[0004] The above information disclosed in this background art is only used to increase the understanding of the background art of this application. Therefore, it may include prior art that is not known to those of ordinary skill in the art. Summary of the Utility Model

[0005] In order to solve the problems that most of the existing freeze-dried powder packaging bottles are composed of simple glass bottles and sealing caps, and they mostly have disadvantages such as poor sealing performance, strong light transmittance, and the material is prone to react with the freeze-dried powder, which may all lead to a decrease in the activity or failure of stem cell exosomes during storage, this application provides a freeze-dried powder packaging bottle for stem cell exosomes.

[0006] The freeze-dried powder packaging bottle for stem cell exosomes provided by this application adopts the following technical solutions:

[0007] A freeze-dried powder packaging bottle for stem cell exosomes, comprising a packaging bottle body, the packaging bottle body is composed of a storage bottle and a mixing bottle, built-in bottles are symmetrically arranged inside the storage bottle, a sealing ring is fixed outside the bottle mouth of the storage bottle, a sealing cap is hermetically connected outside the sealing ring, movable holes are symmetrically opened at the top of the sealing cap, piston rods are movably installed in the movable holes, one end of each piston rod extends into the built-in bottle and is connected with a sealing plug, and diversion ports are symmetrically fixed at the bottom end of the inner wall of the storage bottle.

[0008] Preferably, a light-shielding label is adhesively connected to the outer wall of the storage bottle, through holes are opened inside the built-in bottle, and the through holes communicate with the sealing ring.

[0009] Preferably, an adaptively elastic pressing cap is movably installed inside the movable hole, and a spring is provided at the bottom of the elastic pressing cap.

[0010] Preferably, one end of the piston rod away from the sealing plug passes through the spring and is connected to the bottom of the elastic pressing cap.

[0011] Preferably, the diversion port communicates with the mixing bottle, and a sealing cavity adapted to the sealing plug is provided in the diversion port.

[0012] Preferably, a scale bar is provided on the outer wall of the mixing bottle, and the mixing bottle is externally threaded with a bottle cap.

[0013] In summary, the present application includes the following beneficial technical effects:

[0014] In the present application, the storage bottle and the mixing bottle are set as an integrated structure. The storage bottle provides an outer layer of protection for the lyophilized powder, and the mixing bottle is used for mixing the lyophilized powder raw materials. Through the setting of the internal built-in bottle, during daily placement, the sealing plug is located in the sealing cavity for sealing, forming a multi-layer sealed space, effectively preventing air, moisture, and light from entering. This kind of sealing protection can greatly protect the activity and stability of the lyophilized powder, avoid the quality reduction caused by external factors, extend the shelf life of the lyophilized powder, and through the cooperative setting of the elastic pressing cap, the piston rod, the sealing plug, and the diversion port, the user can easily open the discharge channel of the lyophilized powder. After the discharge is completed, release the elastic pressing cap, and the sealing plug can automatically reset to the sealing cavity for sealing. This design not only facilitates the operation but also ensures the sealing performance of the packaging bottle when not in use, preventing the lyophilized powder from being contaminated. Description of the Drawings

[0015] Figure 1 It is the front view of a packaging bottle for lyophilized stem cell exosomes in an embodiment of the application.

[0016] Figure 2 It is the exploded view of the storage bottle in an embodiment of the application.

[0017] Figure 3 It is the exploded view of the mixing bottle in an embodiment of the application.

[0018] Description of the reference numerals: 1. Packaging bottle body; 2. Storage bottle; 3. Mixing bottle; 4. Light-shielding label; 5. Sealing ring; 6. Sealing cover; 7. Built-in bottle; 8. Through hole; 9. Movable hole; 10. Spring; 11. Elastic pressing cap; 12. Piston rod; 13. Sealing plug; 14. Scale bar; 15. Diversion port; 16. Sealing cavity; 17. Bottle cap. Detailed Description of the Invention

[0019] The following further elaborates on the present application in conjunction with the attached Figures 1-3 for a more detailed description.

[0020] An embodiment of the present application discloses a packaging bottle for freeze-dried stem cell exosomes. Refer to Figures 1-2 , which includes a packaging bottle body 1. The packaging bottle body 1 is composed of a storage bottle 2 and a mixing bottle 3. The bottoms of the storage bottle 2 and the mixing bottle 3 are connected and are an integral structure. A light-shielding label 4 is adhesively connected to the outer wall of the storage bottle 2. The light-shielding label 4 can block external sunlight and ultraviolet rays, thereby protecting the quality of the freeze-dried powder, and information such as product name, ingredients, usage method, production date, shelf life, etc. can be recorded through the light-shielding label 4. Built-in bottles 7 are symmetrically arranged inside the storage bottle 2. Different freeze-dried powders can be stored separately through the two built-in bottles 7, and through holes 8 are opened inside the built-in bottles 7. A sealing ring 5 is fixed outside the bottle mouth of the storage bottle 2. The through hole 8 communicates with the sealing ring 5. The bottle bodies of the storage bottle 2 and the built-in bottles 7 are made of transparent glass material, which is convenient for observing the situation of the internal freeze-dried powder.

[0021] In the present application, a sealing cover 6 is hermetically connected to the outside of the sealing ring 5. Activity holes 9 are symmetrically opened at the top of the sealing cover 6. A piston rod 12 is movably installed in the activity holes 9. One end of the piston rod 12 extends into the built-in bottle 7 and is connected with a sealing plug 13. An elastic pressing cap 11 adapted thereto is movably installed inside the activity holes 9. A spring 10 is provided at the bottom of the elastic pressing cap 11. Due to the elasticity of the spring 10, the elastic pressing cap 11 can be pushed to move in the activity holes 9, and the end of the piston rod 12 away from the sealing plug 13 passes through the spring 10 and is connected to the bottom of the elastic pressing cap 11. Thus, by pressing the elastic pressing cap 11, the sealing plug 13 can be extruded to move.

[0022] Combined with Figure 3 As shown, guide ports 15 are symmetrically fixed at the bottom end of the inner wall of the storage bottle 2. The guide ports 15 communicate with both the built-in bottle 7 and the mixing bottle 3, which is convenient for discharging the freeze-dried powder into the mixing bottle 3. A sealing cavity 16 adapted to the sealing plug 13 is opened in the guide port 15. Both the sealing cavity 16 and the sealing plug 13 are set to be tapered and fit each other, further improving the sealing effect of the contact surface. A scale bar 14 is provided on the outer wall of the mixing bottle 3. The capacity of the internal freeze-dried powder can be observed through the scale bar 14. The mixing bottle 3 is externally threaded and connected with a bottle cap 17.

[0023] The implementation principle of a packaging bottle for freeze-dried stem cell exosomes in an embodiment of the present application is as follows:

[0024] In use, since the storage bottle 2 and the mixing bottle 3 are of an integrated structure, the packaging bottle body 1 can be held by hand for use. During daily placement, the sealing plug 13 is located in the sealing cavity 16 for sealing, forming a sealed space to prevent the entry of air, moisture and light. This kind of sealing protection can effectively protect the activity and stability of the lyophilized powder, avoiding the reduction of its quality due to the influence of external factors. When the lyophilized powder is needed, press down the elastic pressing cap 11, and the elastic pressing cap 11 squeezes the spring 10 to move downward in cooperation with the movable hole 9. Then, the sealing plug 13 is pushed downward by the piston rod 12 and enters the mixing bottle 3, thus disengaging from the sealing cavity 16. At this time, the diversion port 15 can be opened, and then the lyophilized powder inside the two inner bottles 7 both falls downward into the inside of the mixing bottle 3. After the discharge is completed, release the elastic pressing cap 11, and the sealing plug 13 resets to the sealing cavity 16 for sealing. Then, invert the packaging bottle body 1 to make the mixing bottle 3 face upward, and continuously shake the packaging bottle body 1 to fully mix the lyophilized powder inside. The capacity of the lyophilized powder can be observed through the scale bar 14. Then, open the bottle cap 17 to discharge the well-mixed lyophilized powder inside for use.

[0025] Finally, several points should be noted: First, in the description of this application, it should be noted that unless otherwise specified and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense. It can be a mechanical connection or an electrical connection, or it can be the communication inside two components. It can be directly connected. "Up", "down", "left", "right", etc. are only used to represent the relative position relationship. When the absolute position of the object being described changes, the relative position relationship may change;

[0026] Second: In the drawings of the disclosed embodiments of the present utility model, only the structures related to the disclosed embodiments are involved. Other structures can refer to the general design. Without conflict, the same embodiment and different embodiments of the present utility model can be combined with each other;

[0027] Finally: The above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

[0028] The above are all the preferred embodiments of this application, and do not limit the protection scope of this application accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of this application shall be covered within the protection scope of this application.

Claims

1. A freeze-dried powder packaging bottle for stem cell exosomes, comprising a packaging bottle body (1), characterized in that: The packaging bottle body (1) is composed of a storage bottle (2) and a mixing bottle (3). Inside the storage bottle (2), built-in bottles (7) are symmetrically arranged. Outside the bottle mouth of the storage bottle (2), a sealing ring (5) is fixed. A sealing cover (6) is hermetically connected to the outside of the sealing ring (5). On the top of the sealing cover (6), movable holes (9) are symmetrically opened. Inside the movable holes (9), piston rods (12) are movably installed. One end of the piston rod (12) extends into the built-in bottle (7) and is connected to a sealing plug (13). At the bottom end of the inner wall of the storage bottle (2), flow guide openings (15) are symmetrically fixed.

2. The freeze-dried powder packaging bottle for stem cell exosomes according to claim 1, characterized in that: A light-shielding label (4) is adhesively connected to the outer wall of the storage bottle (2). Inside the built-in bottle (7), through holes (8) are opened, and the through holes (8) communicate with the sealing ring (5).

3. A freeze-dried powder packaging bottle for stem cell exosomes according to claim 1, characterized in that: Inside the movable holes (9), elastic pressing caps (11) that are adapted to each other are movably installed. A spring (10) is arranged at the bottom of the elastic pressing cap (11).

4. A packaging bottle for freeze-dried stem cell exosomes according to claim 3, characterized in that: One end of the piston rod (12) away from the sealing plug (13) passes through the spring (10) and is connected to the bottom of the elastic pressing cap (11).

5. A freeze-dried powder packaging bottle for stem cell exosomes according to claim 1, characterized in that: The flow guide openings (15) communicate with the mixing bottle (3). Inside the flow guide openings (15), a sealing cavity (16) adapted to the sealing plug (13) is opened.

6. The dry powder packaging bottle for stem cell exosomes according to claim 5, characterized in that: A scale bar (14) is arranged on the outer wall of the mixing bottle (3). The mixing bottle (3) is externally threaded and connected to a bottle cap (17).

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