Filling system applied to biological pharmacy

Abstract

The filling system sequentially comprises a tank body, a filling pipe and a storage tank from top to bottom, a stirring motor is arranged at the top of the tank body, the output end of the stirring motor is connected with a stirring piece located in an inner cavity of the tank body, the stirring piece comprises a stirring shaft and stirring blades, the stirring shaft is connected with the output end of the stirring motor, and the stirring blades are arranged in the inner cavity of the tank body. The stirring blades are distributed in the circumferential direction of the stirring shaft and are in an arc shape, during stirring, the arc-shaped faces of the stirring blades push materials to be mixed, a feeding port is formed in the side face of the stirring motor, a discharging pipe is arranged at the bottom of the tank body, the bottom of the discharging pipe is sealed, and the filling pipes are evenly distributed in the circumferential direction of the discharging pipe, communicate with an inner cavity of the tank body and are obliquely arranged downwards. And an outlet of the filling pipe corresponds to the storage tank. According to the utility model, the damping effect of medicines on the stirring blades can be reduced, the load of the motor is reduced, the stirring efficiency is improved, and the stirring is more uniform.

Description

Technical Field

[0001] The utility model relates to the technical field of biological medicine production, in particular to a filling system applied to biological medicine. Background Art

[0002] Biomedical engineering is a field that integrates the principles and methods of life science and engineering science to understand the structure, function, and other life phenomena of the human body from an engineering perspective at multiple levels, from molecules to cells, tissues to organs, and even the entire human body. It also encompasses the research of artificial materials, products, devices, and system technologies used for disease prevention and treatment, human function support, and health care. The pharmaceutical industry and biomedical engineering are two pillars of the modern pharmaceutical industry. To ensure the quality of biopharmaceuticals, machines are needed to replace manual labor in drug preparation and prevent the impact of external factors on the drugs.

[0003] In the production process of biopharmaceuticals, drugs often need to be stirred and filled. Some drugs have a large damping effect on the stirring blades, resulting in increased load on the motor, low stirring efficiency and uneven stirring. Utility Model Content

[0004] The purpose of the utility model is to provide a filling system for biopharmaceuticals, which can reduce the damping effect of medicines on stirring blades, reduce the load of the motor, improve the stirring efficiency, and stir more evenly.

[0005] In order to solve the above technical problems, the present invention adopts the following solutions:

[0006] A filling system for biopharmaceuticals comprises, from top to bottom, a tank body, a filling pipe and a storage tank. A stirring motor is provided on the top of the tank body. The output end of the stirring motor is connected to a stirring member located in the inner cavity of the tank body. The stirring member comprises a stirring shaft and stirring blades. The stirring shaft is connected to the output end of the stirring motor. The stirring blades are distributed around the stirring shaft. The stirring blades are arc-shaped. During stirring, the arc-shaped surfaces of the stirring blades push the materials to mix. A feed port is provided on the side of the stirring motor. A discharge pipe is provided at the bottom of the tank body. The bottom of the discharge pipe is sealed. The filling pipes are evenly distributed around the discharge pipe and are connected to the inner cavity of the tank body. The filling pipe is arranged obliquely downward, and the outlet of the filling pipe corresponds to the storage tank.

[0007] In this solution, the stirring motor on the top of the tank body drives the stirring blade to rotate through the stirring shaft to achieve uniform mixing of the materials. The stirring blade adopts an arc-shaped design, which helps to form effective material flow during the stirring process, reduce dead angles, and improve mixing efficiency. During stirring, the curved surface of the stirring blade pushes the drug material to mix. The curved surface of the stirring blade can reduce the damping caused by the drug during rotation, thereby reducing the load of the stirring motor. The filling tubes are evenly distributed around the discharge tube and connected to the inner cavity of the tank body, which helps to achieve uniform distribution of the material. The filling tube is set obliquely downward, which is conducive to the smooth flow of the material under the action of gravity, reduces the risk of blockage, and improves the filling efficiency. The outlet of the filling tube corresponds precisely to the storage tank, ensuring the accuracy and stability of the filling process and reducing the risk of material waste and cross contamination.

[0008] Optionally, the stirring blade is made of stainless steel, and the surface of the stirring blade is grid-shaped.

[0009] Optionally, there are three stirring blades, and the angle between any two adjacent stirring blades is 120°.

[0010] Optionally, the length of the stirring blade is adapted to the depth of the tank.

[0011] Optionally, the end surface of the stirring blade adjacent to the inner wall of the tank is provided with a scraper in contact with the inner wall of the tank.

[0012] Optionally, a material blocking pipe is provided vertically downward at the outlet end of the filling pipe, and the storage tank is located directly below the material blocking tank.

[0013] Optionally, a vibration motor is provided on the side wall of the filling tube and the side wall of the tank body.

[0014] Optionally, the inclination angle of the filling tube is 20°.

[0015] Optionally, the discharge pipe is provided with an electromagnetic valve located above the canning pipe.

[0016] The utility model has the beneficial effects:

[0017] 1. In the present invention, the stirring motor on the top of the tank body drives the stirring blade to rotate through the stirring shaft to achieve uniform mixing of the materials. The stirring blade adopts an arc-shaped design, which helps to form an effective material flow during the stirring process, reduce dead angles, and improve mixing efficiency. During stirring, the curved surface of the stirring blade promotes the mixing of the medicine and the material. The curved surface of the stirring blade can reduce the damping caused by the medicine during rotation, thereby reducing the load of the stirring motor.

[0018] 2. The filling tubes are evenly distributed around the discharge tube and connected to the inner cavity of the tank, which helps to achieve uniform distribution of materials. The filling tubes are set obliquely downward, which is conducive to the smooth flow of materials under the action of gravity, reduces the risk of blockage, and improves filling efficiency. The outlet of the filling tube corresponds precisely to the storage tank, ensuring accuracy and stability during the filling process and reducing the risk of material waste and cross contamination. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural diagram of the utility model;

[0020] Figure 2 A schematic diagram of the top view of the assembly of the stirring blade and the stirring shaft;

[0021] Figure 3 This is a schematic diagram of the top view of the assembly of the discharge pipe and the filling pipe.

[0022] Figure markings: 1-tank body, 2-stirring shaft, 3-stirring blade, 4-scraper, 5-stirring motor, 6-feed port, 7-discharge pipe, 8-electromagnetic valve, 9-filling pipe, 10-blocking pipe, 11-vibration motor, 12-storage tank. DETAILED DESCRIPTION

[0023] The present invention will be further described in detail below in conjunction with the embodiments and drawings, but the implementation manner of the present invention is not limited thereto.

[0024] In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "longitudinal", "lateral", "horizontal", "inside", "outside", "front", "back", "top", "bottom", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, or are the orientation or position relationship in which the utility model product is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0025] In the description of the present invention, it should also be noted that, unless otherwise expressly specified or limited, the terms "disposed," "opened," "installed," "connected," and "connected" should be understood in a broad sense. For example, they may refer to fixed connections, detachable connections, or integral connections; they may refer to mechanical connections or electrical connections; they may refer to direct connections or indirect connections through an intermediate medium; and they may refer to internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on the specific circumstances.

[0026] Example

[0027] A filling system for biopharmaceuticals comprises, from top to bottom, a tank body 1, a filling pipe 9 and a storage tank 12. A stirring motor 5 is provided on the top of the tank body 1. The output end of the stirring motor 5 is connected to a stirring member located in the inner cavity of the tank body 1. The stirring member comprises a stirring shaft 2 and stirring blades 3. The stirring shaft 2 is connected to the output end of the stirring motor 5. The stirring blades 3 are distributed around the stirring shaft 2. The stirring blades 3 are arc-shaped. When stirring, the arc-shaped surface of the stirring blades 3 pushes the materials to mix. A feeding port 6 is provided on the side of the stirring motor 5. A discharge pipe 7 is provided at the bottom of the tank body 1. The bottom of the discharge pipe 7 is sealed. Figure 3 As shown, the filling pipes 9 are evenly distributed around the discharge pipe 7 and connected to the inner cavity of the tank body 1 . The filling pipes 9 are arranged obliquely downward, and the outlet of the filling pipes 9 corresponds to the storage tank 12 .

[0028] In this embodiment, Figure 1 As shown, the tank body 1 is installed on the bracket, and the stirring motor 5 on the top of the tank body 1 drives the stirring blade 3 to rotate through the stirring shaft 2 to achieve uniform mixing of the materials. The stirring blade 3 adopts an arc design, which is helpful to form an effective material flow during the stirring process, reduce dead angles, and improve mixing efficiency. During stirring, the curved surface of the stirring blade 3 pushes the drug material to mix. The curved surface of the stirring blade 3 can reduce the damping caused by the drug during rotation, thereby reducing the load of the stirring motor 5. The bottom of the discharge pipe 7 is an upwardly protruding spherical surface, which can accelerate the speed of the material flowing to the filling pipe 9. The filling pipe 9 is evenly distributed around the discharge pipe 7 and is connected to the inner cavity of the tank body 1, which helps to achieve uniform distribution of the material. The filling pipe 9 is set obliquely downward, which is conducive to the smooth flow of the material under the action of gravity, reduces the risk of blockage, and improves the filling efficiency. The outlet of the filling pipe 9 precisely corresponds to the storage tank 12, which ensures the accuracy and stability of the filling process and reduces the risk of material waste and cross contamination.

[0029] Furthermore, the stirring blade 3 is made of stainless steel, and the surface of the stirring blade 3 is grid-shaped.

[0030] Specifically, such as Figure 1As shown, stainless steel is known for its excellent corrosion resistance and high strength, which enables the stirring blade 3 to maintain long-term stability and durability in the biopharmaceutical process, especially when corrosive or biologically active substances are involved; the grid-like surface not only increases the specific surface area of ​​the stirring blade 3, which helps to improve the mixing efficiency, but also makes the blade surface easier to clean and disinfect. In the field of biopharmaceuticals, strict cleaning and disinfection procedures are essential to prevent microbial contamination and cross-contamination. The grid-like structure can reduce material residue, reduce the difficulty of cleaning, and ensure that the blade surface is thoroughly cleaned; the grid shape can increase the contact area between the stirring blade 3 and the material, making During the stirring process, the material is more susceptible to mixing effects such as shearing, stretching and folding, which helps to accelerate the dispersion and uniform mixing of the material, improve the mixing efficiency, and help release bubbles in the material and reduce agglomeration; during the stirring process, the grid-shaped blade surface can form more flow channels and eddies, promoting the circulation and flow of the material in the tank body 1, which helps to reduce stirring dead corners, improve the uniformity of the material, and ensure that the material received by each filling tube 9 has consistent properties and concentration; the grid shape also helps to enhance the structural strength of the stirring blade 3. The grid structure can disperse stress and reduce the risk of blade deformation or damage caused by material impact and stirring force.

[0031] Furthermore, there are three stirring blades 3, and the angle between any two adjacent stirring blades 3 is 120°.

[0032] Specifically, such as Figure 2 As shown, the three stirring blades 3 are evenly distributed on the stirring shaft 2 at an angle of 120°, forming a symmetrical stirring layout. This layout helps to form a uniform fluid dynamic environment during the stirring process, so that the material can be subjected to the same stirring action in all directions, thereby achieving more uniform mixing. The symmetrical stirring blade 3 design reduces dead angles during the stirring process, so that the material can more fully participate in the mixing process, thereby improving the mixing efficiency. The three stirring blades 3 are distributed at the maximum interval so that each blade can cover the largest possible stirring area, which helps to increase the contact area between the stirring blade 3 and the material, thereby improving the stirring efficiency; the three blades are distributed at equal intervals, which helps to maintain the overall balance of the stirrer. When rotating at high speed, this balance can reduce vibration and noise, thereby extending the service life of the stirrer.

[0033] Furthermore, the length of the stirring blade 3 is adapted to the depth of the tank body 1 .

[0034] Specifically, when the length of the stirring blade 3 is adapted to the depth of the tank body 1, the blade can fully cover the material in the tank body 1, thereby ensuring that the material can be effectively stirred at all levels. This adaptability helps to reduce dead corners in the stirring process, allowing the material to be more fully mixed, thereby improving mixing efficiency and uniformity.

[0035] Furthermore, the end surface of the stirring blade 3 adjacent to the inner wall of the tank body 1 is provided with a scraper 4 that contacts the inner wall of the tank body 1 .

[0036] Specifically, the scraper 4 ensures that the mixing blade 3 can stick to the inner wall of the tank body 1 during rotation, thereby reducing the accumulation of materials at the edge and bottom of the tank body 1 and avoiding the formation of mixing dead corners, which helps to achieve comprehensive and uniform mixing of materials in the tank body 1. The close contact between the scraper 4 and the inner wall of the tank body 1 helps to remove material residues attached to the tank wall during the mixing process, which not only reduces material waste, but also reduces the difficulty and cost of cleaning. The scraper 4 is usually made of wear-resistant material and can withstand wear and impact during the mixing process.

[0037] Furthermore, a material blocking pipe 10 is provided vertically downward at the outlet end of the filling pipe 9, and the storage tank 12 is located directly below the material blocking tank.

[0038] Furthermore, a vibration motor 11 is provided on the side wall of the filling tube 9 and the side wall of the tank body 1 .

[0039] Furthermore, the inclination angle of the filling tube 9 is 20°.

[0040] Furthermore, the discharge pipe 7 is provided with an electromagnetic valve 8 located above the canning pipe.

[0041] Specifically, the vertical downward retaining tube 10 at the outlet end of the filling tube 9 mainly plays a role of buffering and guiding. When the material flows out of the filling tube 9, the retaining tube 10 can slow down the flow rate of the material to prevent the material from directly impacting the storage tank 12 below, thereby reducing material splashing. The setting of the vibration motor 11 is to solve the problem of blockage or poor flow of materials that may occur during the filling process. Through vibration, it can promote the flow of materials in the filling tube 9 and the tank body 1, ensuring that the material can smoothly pass through the filling tube 9 and be evenly distributed in the storage tank 12, improving the filling efficiency, reducing the downtime caused by material blockage, and ensuring the continuity and stability of the filling process. The inclination angle of the filling tube 9 is an important design parameter, which directly affects the flow rate of the material and the filling effect. The 20° inclination angle is optimized to balance the fluidity and filling speed of the material. This angle can ensure that the material can flow out of the filling tube 9 smoothly while avoiding splashing caused by excessive flow rate. The electromagnetic valve 8 is located above the filling tube 9 and is used to accurately control the flow rate and filling time of the material.

[0042] The above description is only a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Based on the technical essence of the present invention and within the spirit and principles of the present invention, any simple modification, equivalent replacement and improvement of the above embodiment shall still fall within the scope of protection of the technical solution of the present invention.

Claims

1. A filling system for biopharmaceuticals, characterized in that: From top to bottom, the invention comprises a tank body (1), a filling pipe (9) and a storage tank (12). A stirring motor (5) is provided on the top of the tank body (1). The output end of the stirring motor (5) is connected to a stirring member located in the inner cavity of the tank body (1). The stirring member comprises a stirring shaft (2) and a stirring blade (3). The stirring shaft (2) is connected to the output end of the stirring motor (5). The stirring blade (3) is distributed around the stirring shaft (2). The stirring blade (3) is arc-shaped. When stirring, the arc-shaped surface of the stirring blade (3) pushes the material to mix. A feeding port (6) is provided on the side of the stirring motor (5). A discharge pipe (7) is provided at the bottom of the tank body (1). The bottom of the discharge pipe (7) is sealed. The filling pipe (9) is evenly distributed around the discharge pipe (7) and is connected to the inner cavity of the tank body (1). The filling pipe (9) is arranged obliquely downward. The outlet of the filling pipe (9) corresponds to the storage tank (12).

2. A filling system for biopharmaceuticals according to claim 1, characterized in that: The stirring blade (3) is made of stainless steel, and the surface of the stirring blade (3) is in a grid shape.

3. A filling system for biopharmaceuticals according to claim 2, characterized in that: The stirring blades (3) are provided with three pieces, and the angle between any two adjacent stirring blades (3) is 120°.

4. A filling system for biopharmaceuticals according to claim 3, characterized in that: The length of the stirring blade (3) is adapted to the depth of the tank body (1).

5. A filling system for biopharmaceuticals according to claim 4, characterized in that: The end surface of the stirring blade (3) adjacent to the inner wall of the tank body (1) is provided with a scraper (4) in contact with the inner wall of the tank body (1).

6. The filling system for biopharmaceuticals according to claim 1, characterized in that: The outlet end of the filling pipe (9) is provided with a material blocking pipe (10) extending vertically downward, and the storage tank (12) is located directly below the material blocking tank.

7. A filling system for biopharmaceuticals according to claim 6, characterized in that: A vibration motor (11) is provided on the side wall of the filling tube (9) and the side wall of the tank body (1).

8. The filling system for biopharmaceuticals according to claim 1, characterized in that: The inclination angle of the filling tube (9) is 20°.

9. The filling system for biopharmaceuticals according to claim 1, characterized in that: The discharge pipe (7) is provided with an electromagnetic valve (8) located above the canning pipe.

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