Dry tablet for milk detection
By designing milk detection dry tablets, the blockage problem caused by the high breast milk concentration of the milk component analyzer is solved, and efficient and simple milk nutrient detection is achieved, which improves the detection efficiency and reliability.
Patent Information
- Application Number
- CN202422711941.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-07
- Publication Date
- 2025-08-26
- Estimated Expiration
- 2034-11-07
AI Technical Summary
The existing milk component analyzers are prone to high concentrations when detecting breast milk, and the detection efficiency is low, making it impossible to achieve efficient continuous detection.
A dry milk detection tablet is designed, including a filter layer, a reagent layer and a support layer. The filter layer is used to filter impurities. The reagent layer is used to react with the nutrients of the milk and present a color. The support layer provides structural support. The nutrient content in the milk is directly detected through colorimetric method to avoid equipment blockage and cleaning steps.
It realizes efficient detection of milk nutrients, avoids equipment blockage, improves detection efficiency, and simplifies operational processes.
Smart Images
Figure CN223272424U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of medical testing technology, and in particular to a milk testing dry slide. Background Art
[0002] Infancy is the period of fastest growth and development for children, requiring an adequate intake of nutrients to ensure normal growth and development. Breast milk is the primary food for early infants. Chronic insufficient total breast milk calories can lead to emaciation, developmental delays, poor weight gain, decreased immunity, and increased susceptibility to disease. On the other hand, chronic excessive caloric intake can lead to obesity. Therefore, it is necessary to analyze the nutritional composition of breast milk, the primary food for infants, including the three major nutrients: protein, fat, and lactose, as well as minerals that are also essential for growth and development.
[0003] Currently, trace element minerals can be measured using a trace element analyzer, while the three major nutrients in breast milk—protein, fat, and lactose—require a specialized breast milk composition analyzer for quantitative testing. Guiding breastfeeding based on breast milk composition testing is a necessary scientific measure to promote healthy infant growth and is crucial for improving breastfeeding quality. However, currently used breast milk composition analyzers are prone to clogging due to the high concentration of some breast milk. Furthermore, they require cleaning after each test, resulting in low efficiency. Utility Model Content
[0004] The present application proposes a milk detection dry plate for detecting the content of nutrients in milk.
[0005] In order to achieve the above objectives, this application adopts the following technical solutions:
[0006] In a first aspect, a milk testing dry sheet is provided, which is stacked in sequence from top to bottom with a filter layer, a reagent layer, and a support layer; the filter layer is used to filter impurities in the milk to be tested; the support layer is used to provide structural support for the milk testing dry sheet; the reagent layer includes multiple reagent areas, each reagent area includes a reagent for reacting with a milk nutrient, and the color presented by the reagent in the reagent area after reacting with the corresponding milk nutrient is used to characterize the content of the corresponding milk nutrient.
[0007] Furthermore, the reagent area includes a reagent carrying area and a reaction buffer area; the reagent carrying area is centrally arranged on the reagent area; the reagent carrying area is used to carry reagents that react with milk nutrients; the reaction buffer area is used to provide a liquid diffusion area after the reagent reacts with the milk nutrients.
[0008] Furthermore, the milk testing dry sheet further includes a dilution layer; the dilution layer is attached to the upper side of the filter layer; and the dilution layer is used to dilute the milk to be tested.
[0009] Furthermore, the dilution layer is composed of a carrier and a dilution reagent; the carrier is a cellulose acetate membrane, and the dilution reagent is physiological saline.
[0010] Furthermore, the reagent layer includes a plurality of reagent area groups, wherein the plurality of reagent areas included in the reagent area groups are respectively used to detect different milk nutrients, and the plurality of reagent areas included in each reagent area group are identical.
[0011] Furthermore, a plurality of isolation zones are provided on the reagent layer, each isolation zone being provided between two reagent areas, and the isolation zone is used to prevent the liquid in the reagent area from diffusing to other reagent areas.
[0012] Furthermore, the milk testing dry sheet also includes a shell, which is made of plastic; the shell is formed by bonding an upper shell and a lower shell by ultrasonic bonding.
[0013] Furthermore, the multiple reagent areas include a protein detection reagent area, a fat detection reagent area, and a lactose detection reagent area. The protein detection reagent area includes a reagent that changes color when reacting with protein, the fat detection reagent area includes a reagent that changes color when reacting with fat, and the lactose detection reagent area includes a reagent that changes color when reacting with lactose.
[0014] Furthermore, the reagent area also includes an acidic reagent or an alkaline reagent that provides a reaction environment for the reagent and the milk nutrients.
[0015] Furthermore, the support layer is made of PET material.
[0016] The present application proposes a milk testing dry sheet, which comprises, from top to bottom, a filter layer, a reagent layer, and a support layer. The filter layer is used to filter impurities from the milk to be tested, the support layer provides structural support for the milk testing dry sheet, and the reagent layer includes multiple reagent areas, each of which contains a reagent for reacting with a milk nutrient. The color of the reagent in the reagent area after reacting with the corresponding milk nutrient is used to indicate the content of the corresponding milk nutrient. The provided milk testing dry sheet allows, after collecting the milk to be tested, to be directly dripped onto the upper side of the milk testing dry sheet. The filter layer first filters the impurities, and then, after the impurities react with the reagent in the reagent layer, the colorimetric analysis of the reaction colors of the different reagent areas can be used to determine the content of different milk nutrients in the milk to be tested. This eliminates the problem of clogging the milk testing equipment and eliminates the need for cleaning. A new milk testing dry sheet can be simply taken to start the next test, thereby improving the efficiency of milk nutrient detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 A schematic structural diagram of a dry plate for milk detection provided in an embodiment of the present application;
[0018] Figure 2 A schematic diagram of the reagent layer structure of a milk detection dry slide provided in an embodiment of the present application;
[0019] Figure 3 A schematic structural diagram of another dry plate for milk detection provided in an embodiment of the present application;
[0020] Figure 4 A schematic diagram of the reagent layer structure of another dry slide for milk detection provided in an embodiment of the present application;
[0021] Figure 5 A schematic diagram of the reagent layer structure of another dry slide for milk detection provided in an embodiment of the present application;
[0022] Figure 6 A schematic structural diagram of another dry plate for milk detection provided in an embodiment of the present application;
[0023] Figure 7 A schematic structural diagram of another dry plate for milk detection provided in an embodiment of the present application;
[0024] Reference numerals:
[0025] The milk detection dry slide 100 , the filter layer 110 , the reagent layer 120 , the reagent area 121 , the reagent carrying area 121 - 1 , the reaction buffer area 121 - 1 , the reagent area group 122 , the isolation zone 123 , the support layer 130 , the dilution layer 140 , and the housing 150 . DETAILED DESCRIPTION
[0026] In order to make the purpose, technical solutions and advantages of the present application more clear, the present application is further described in detail below with reference to the accompanying drawings and embodiments. Examples of embodiments are shown in the accompanying drawings, in which the same or similar reference numerals throughout represent the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present application and are not to be construed as limiting the present application. In addition, it should be understood that the specific embodiments described herein are merely used to explain the present application and are not intended to limit the present application.
[0027] In the description of this application, it should be understood that the terms "length", "width", "up", "down", "left", "right", "horizontal", "top", "bottom", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they should not be understood as limitations on this application.
[0028] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features being referred to. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more features. Throughout the description of this application, "plurality" means two or more, unless otherwise specifically defined.
[0029] In the description of this application, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections, electrical connections, or mutual communication; they can refer to direct connections or indirect connections through an intermediate medium; they can refer to internal communication between two components or the interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on specific circumstances.
[0030] In this application, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Moreover, a first feature being "above," "above," and "above" a second feature may include the first feature being directly above or obliquely above the second feature, or may simply mean that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature may include the first feature being directly below or obliquely below the second feature, or may simply mean that the first feature is lower in level than the second feature.
[0031] The disclosure below provides many different embodiments or examples for realizing different structures of the present application. In order to simplify the disclosure of the present application, the components and settings of specific examples are described below. Of course, they are merely examples and are not intended to limit the present application. In addition, the present application may repeat reference numbers and / or reference letters in different examples, and such repetition is for the purpose of simplicity and clarity, and does not itself indicate the relationship between the various embodiments and / or settings discussed. In addition, the present application provides examples of various specific processes and materials, but those of ordinary skill in the art will appreciate the application of other processes and / or the use of other materials.
[0032] The present application proposes a milk testing dry sheet, which comprises, from top to bottom, a filter layer, a reagent layer, and a support layer. The filter layer is used to filter impurities from the milk to be tested, the support layer provides structural support for the milk testing dry sheet, and the reagent layer includes multiple reagent areas, each of which contains a reagent for reacting with a milk nutrient. The color of the reagent in the reagent area after reacting with the corresponding milk nutrient is used to indicate the content of the corresponding milk nutrient. The provided milk testing dry sheet allows, after collecting the milk to be tested, to be directly dripped onto the upper side of the milk testing dry sheet. The filter layer first filters the impurities, and then, after the impurities react with the reagent in the reagent layer, the colorimetric analysis of the reaction colors of the different reagent areas can be used to determine the content of different milk nutrients in the milk to be tested. This eliminates the problem of clogging the milk testing equipment and eliminates the need for cleaning. A new milk testing dry sheet can be simply taken to start the next test, thereby improving the efficiency of milk nutrient detection.
[0033] In some embodiments, Figure 1 A schematic structural diagram of a milk testing dry sheet is shown, wherein the milk testing dry sheet 100 includes a filter layer 110, a reagent layer 120, and a support layer 130. The upper side of the reagent layer 120 is bonded to the lower side of the filter layer 110, and the lower side of the reagent layer 120 is bonded to the upper side of the support layer 130.
[0034] The filter layer 110 may be a membrane with a special microporous structure, which is used to filter out impurities such as solid particles and sediments in the milk to be tested, thereby improving the stability of the dry film detection of milk nutrients and the accuracy of the analysis.
[0035] The support layer 130 may be made of PET material to provide structural support for the milk detection dry sheet and maintain the stability of the milk detection dry sheet.
[0036] The reagent layer 120 includes a plurality of reagent areas 121 , each of which includes a reagent for reacting with a milk nutrient. The color of the reagent in the reagent area after reacting with the corresponding milk nutrient is used to represent the content of the corresponding milk nutrient.
[0037] In some embodiments, for the three major nutrients contained in breast milk, protein, fat and lactose, the multiple reagent areas 121 set in the reagent layer 120 can be a protein detection reagent area, a fat detection reagent area and a lactose detection reagent area respectively.
[0038] The protein detection reagent area includes a reagent that changes color when reacting with protein, the fat detection reagent area includes a reagent that changes color when reacting with fat, and the lactose detection reagent area includes a reagent that changes color when reacting with lactose.
[0039] For example, the protein detection reagent area includes bromocresol green reagent, which can react with protein in an acidic environment to form a blue-green complex; the fat detection reagent area includes lipase reagent, which can react with fat to produce hydrogen peroxide or other colored products; the lactose detection reagent area includes lactase and catalase reagents, which can react with lactose to produce color.
[0040] Optionally, the reagent area 121 also includes an acidic reagent or an alkaline reagent that provides a reaction environment for the reagent and the milk nutrients.
[0041] For example, the protein detection reagent area includes a succinate buffer that provides a reaction environment for the bromocresol green reagent and the protein.
[0042] When using the milk testing dry sheet 100 provided in the present application to test milk nutrients, the milk to be tested is dropped onto the milk testing dry sheet 100, and the filter layer 110 first filters impurities in the milk to be tested; the milk then penetrates into the multiple reagent areas 121 in the reagent layer 120, such as the protein detection reagent area, the fat detection reagent area, and the lactose detection reagent area, and reacts with the reagent in each reagent area 121. Each reagent area 121 shows a color after the reaction, so that medical staff can determine the content of each milk nutrient based on the color of the reacted different reagent areas and compare it with the standard color card.
[0043] In some embodiments, in combination with the above Figure 1 The milk detection dry sheet 100 shown is as follows Figure 2 As shown, each reagent area 121 of the milk detection dry sheet 100 includes a reagent carrying area 121 - 1 and a reaction buffer area 121 - 2 , and the reagent carrying area 121 - 1 is centrally located on the reagent area 121 .
[0044] The reagent carrying area 121 - 1 is used to carry the reagent that reacts with the milk nutrients, and the reaction buffer area 121 - 2 is used to provide a liquid diffusion area after the reagent reacts with the milk nutrients.
[0045] It can be understood that the product after the milk nutrients in the milk to be tested react with the reagent in the reagent area 121 will diffuse on the reagent layer 120 along with the milk to be tested, which will cause the color to diffuse outward. By arranging the reagent-carrying area 121-1 that carries the reagent in the center on the reagent area 121 and including a reaction buffer area for outward diffusion, it can be ensured that after the reagent reacts with the milk nutrients, the product is allowed to diffuse to a certain extent without affecting other reagent areas 121, thereby ensuring the accuracy of the test results of each reagent area 121.
[0046] In some embodiments, in combination with Figure 1The milk detection dry sheet 100 shown is as Figure 3 As shown, the milk testing dry sheet 100 further includes a dilution layer 140. The dilution layer 140 is attached to the upper side of the filter layer 110 and is used to dilute the milk to be tested.
[0047] The dilution layer 140 is composed of a carrier and a dilution agent. The carrier may be a cellulose acetate membrane, and the dilution agent may be physiological saline.
[0048] It is understandable that since some breast milk has a higher viscosity, in order to avoid affecting the deviation of the test results, the milk testing dry plate provided in this application dilutes the dripped milk by adding a dilution layer to reduce the concentration of the milk to be tested. It is only necessary to perform corresponding calculations after obtaining the results through observation to ensure the reliability of milk testing.
[0049] In some embodiments, combined Figure 1 The milk detection dry sheet 100 shown is as follows Figure 4 As shown, the reagent layer 120 of the milk detection dry sheet 100 includes multiple reagent area groups 122. The multiple reagent areas 121 included in the reagent area groups 122 are respectively used to detect different milk nutrients. The multiple reagent areas included in each reagent area group 122 are the same.
[0050] For example, the first reagent area group includes a first protein detection reagent area, a first fat detection reagent area, and a first lactose detection reagent area; the second reagent area group includes a second protein detection reagent area, a second fat detection reagent area, and a second lactose detection reagent area; the third reagent area group includes a third protein detection reagent area, a third fat detection reagent area, and a third lactose detection reagent area; that is, within each reagent area group, the multiple reagent areas included are all used to detect different milk nutrients, and between the reagent area groups, the types and quantities of the reagent areas included in each reagent area group are the same as those in other reagent area groups.
[0051] It can be understood that by providing multiple identical reagent blocks 122 on the milk testing dry slide 100, multiple reactions can be performed on the same sample of milk to be tested under the same environment, thereby avoiding accidental events and improving the reliability of milk nutrient content detection.
[0052] In some embodiments, combined Figure 1 The milk detection dry sheet 100 shown is as follows Figure 5 As shown, a plurality of isolation bands 123 are further provided on the reagent layer 120 of the milk detection dry sheet 100. Each isolation band 123 is provided between two reagent areas 121, and is used to prevent the liquid in a reagent area 121 from diffusing to other reagent areas 121.
[0053] The isolation belt 123 can be made of PET material and is pressed between every two reagent areas 121 on the upper and lower sides of the reagent layer 120 to prevent liquid diffusion between different reagent areas 121 after the isolation belt 123 is pressed.
[0054] It can be understood that the product after the milk nutrients in the milk to be tested react with the reagent in the reagent area 121 will diffuse on the reagent layer 120 along with the milk to be tested, which will also cause the color to diffuse outward. By providing the isolation zone 123, the liquid diffusion between different reagent areas 121 can be blocked, thereby ensuring the accuracy of the test results of each reagent area 121.
[0055] In some embodiments, combined Figure 1 The milk detection dry sheet 100 shown is as follows Figure 6 As shown, the milk testing dry strip 100 further includes a housing 150 .
[0056] The housing 150 is made of plastic and is formed by bonding an upper housing and a lower housing by ultrasonic bonding, thereby protecting the milk testing dry sheet 100 and preventing the milk testing dry sheet 100 from being damaged during transportation or storage.
[0057] In some embodiments, combined Figures 1-6 The milk detection dry sheet 100 shown is as follows Figure 7 As shown, the dry slide 100 for milk detection proposed in the present application includes a dilution layer 140, a filter layer 110, a reagent layer 120, a support layer 130, and a housing 150. The reagent layer 120 includes a plurality of reagent block groups 122, each of which includes a plurality of reagent areas 121. An isolation zone 123 is provided between any two adjacent reagent areas 121. Each reagent area 121 includes a reagent carrying area 121-1 and a reaction buffer area 121-2.
[0058] By using the milk detection dry sheet provided by the device, after collecting the milk to be tested, the milk to be tested can be directly dropped onto the upper side of the milk detection dry sheet. First, the impurities therein are filtered out by the filter layer. Then, after reacting with the reagent in the reagent layer, the content of different milk nutrients in the milk to be tested can be determined by colorimetrically comparing the colors after the reaction of different reagent areas. In addition, the provision of isolation zones and / or reaction buffer zones can avoid the influence between different reagent areas, thereby ensuring the efficiency and reliability of milk nutrient detection.
[0059] The above are only preferred embodiments of the present application and are not intended to limit the present application. Any modifications, equivalent replacements, and improvements made within the spirit and principles of the present application should be included in the scope of protection of the present application.
Claims
1. A dry sheet for milk detection, characterized in that: A filter layer, a reagent layer, and a support layer are stacked in sequence from top to bottom; The filter layer is used to filter impurities in the milk to be tested; The support layer is used to provide structural support for the milk detection dry sheet; The reagent layer includes a plurality of reagent areas, each of which includes a reagent for reacting with a milk nutrient. The color presented by the reagent in the reagent area after reacting with the corresponding milk nutrient is used to characterize the content of the corresponding milk nutrient.
2. The dry sheet for milk detection according to claim 1, characterized in that: The reagent area includes a reagent carrying area and a reaction buffer area; the reagent carrying area is centrally arranged on the reagent area; The reagent carrying area is used to carry reagents that react with milk nutrients; The reaction buffer zone is used to provide a liquid diffusion area after the reagent reacts with the milk nutrients.
3. The dry sheet for milk detection according to claim 1 or 2, characterized in that: The milk detection dry sheet also includes a dilution layer; The dilution layer is attached to the upper side of the filter layer; the dilution layer is used to dilute the milk to be tested.
4. The dry sheet for milk detection according to claim 3, characterized in that: The dilution layer is composed of a carrier and a dilution reagent; The carrier is cellulose acetate membrane, and the diluent is physiological saline.
5. The dry sheet for milk detection according to claim 1 or 2, characterized in that: The reagent layer includes a plurality of reagent area groups. The plurality of reagent areas included in the reagent area groups are respectively used to detect different milk nutrients. The plurality of reagent areas included in each reagent area group are identical.
6. The dry sheet for milk detection according to claim 1 or 2, characterized in that: A plurality of isolation zones are provided on the reagent layer, each of which is provided between two reagent areas. The isolation zones are used to prevent the liquid in the reagent area from diffusing to other reagent areas.
7. The dry sheet for milk detection according to claim 1 or 2, characterized in that: The milk detection dry sheet also includes a shell, which is made of plastic; The shell is obtained by bonding an upper shell and a lower shell by ultrasonic bonding.
8. The dry sheet for milk detection according to claim 1 or 2, characterized in that: The multiple reagent areas include a protein detection reagent area, a fat detection reagent area, and a lactose detection reagent area. The protein detection reagent area includes a reagent that changes color when reacting with protein, the fat detection reagent area includes a reagent that changes color when reacting with fat, and the lactose detection reagent area includes a reagent that changes color when reacting with lactose.
9. The dry sheet for milk detection according to claim 1 or 2, characterized in that: The reagent area also includes an acidic reagent or an alkaline reagent that provides a reaction environment for the reagent and the milk nutrients.
10. The dry sheet for milk detection according to claim 1 or 2, characterized in that: The supporting layer is made of PET material.