Paper diaper capable of detecting lactose metabolism

Abstract

The utility model discloses a paper diaper capable of detecting lactose metabolism. The paper diaper comprises a paper diaper body and a detection module. The paper diaper body comprises an inner surface layer, an absorption layer and a waterproof layer which are sequentially arranged from inside to outside. The detection module is located between the absorption layer and the waterproof layer to detect lactose metabolism in urine; the detection module has a display unit to display a detection change. According to the utility model, the lactose metabolism related markers in the urine of the infant can be rapidly and conveniently detected, and the lactose metabolism condition of the infant can be monitored.

Description

Technical Field

[0001] The utility model relates to the technical field of sanitary products, in particular to a diaper capable of detecting lactose metabolism. Background Art

[0002] Lactose intolerance (LI) refers to lactose malabsorption caused by insufficient lactase or low lactase activity, which subsequently leads to gastrointestinal symptoms. Diagnostic methods for LI include hydrogen breath testing, lactose tolerance testing, fecal reducing sugar and pH measurements, urine galactose measurement, jejunal mucosal biopsy, and genetic testing. However, most of these tests are not suitable for infants and young children: breath testing and lactose tolerance testing have long testing cycles and require high patient compliance; fecal reducing sugar and pH measurements have a high false-positive rate and are difficult to obtain; jejunal mucosal biopsy is an invasive procedure, difficult to perform, and cumbersome; genetic testing is primarily used in genetic research and has not been widely adopted in clinical practice. Among these, urine galactose measurement offers advantages such as high sensitivity and specificity, as well as being noninvasive and convenient. The principle is that lactose is broken down into glucose and galactose in the small intestine. After absorption by intestinal epithelial cells, most of the galactose is converted to glucose in the liver or synthesized into galactoside, which contributes to the formation of cerebrosides, while a small portion is excreted in the urine. Determination of urine galactose content is one of the commonly used methods for LI metabolic diseases.

[0003] Individuals with lactose intolerance are unable to fully break down the lactose they consume, resulting in lower galactose levels in their urine compared to lactose-tolerant individuals. Therefore, testing urine for galactose levels can reflect an individual's lactose intolerance. Urine galactose testing is an ideal LI test, but the difficulty lies in collecting urine samples. Because infants and young children have incompletely developed nervous systems, they cannot control their urination and therefore need to wear diapers for extended periods. Urine excreted by infants and young children is readily absorbed by diapers, making it difficult to collect sufficient urine for testing.

[0004] Existing urine galactose testing products are not optimized for the difficulty of collecting urine from infants and young children, and the testing process is cumbersome. This can affect user acceptance in home self-testing scenarios. Therefore, there is a need for a product that can easily detect galactose in infant urine, address the technical issues of difficult urine collection, simplify the operating procedures, and be suitable for home self-testing and continuous monitoring. Utility Model Content

[0005] The present invention aims to at least partially address one of the technical problems of the aforementioned technologies. To this end, the present invention provides a diaper capable of detecting lactose metabolism, thereby enabling rapid and convenient detection of lactose metabolism-related markers in infant urine and monitoring the infant's lactose metabolism.

[0006] To achieve the above-mentioned purpose, the present invention provides a diaper capable of detecting lactose metabolism, comprising:

[0007] The diaper body comprises an inner surface layer, an absorbent layer and a waterproof layer arranged in sequence from the inside to the outside;

[0008] A detection module is located between the absorption layer and the waterproof layer to detect lactose metabolism in urine; the detection module has a display unit to display detection changes.

[0009] According to an embodiment of the present invention, a diaper capable of detecting lactose metabolism is provided. After an infant wearing the diaper urinates, the urine passes through the inner surface layer and enters the absorbent layer. A portion of the urine soaks the detection module, which reacts with galactose, lactose, lactase, glucose, and the like in the urine. The detection changes are displayed on the display unit, allowing for rapid interpretation of the results. Therefore, the present invention can quickly and conveniently detect lactose metabolism-related markers in infant urine and monitor the infant's lactose metabolism.

[0010] In addition, the diaper capable of detecting lactose metabolism according to the above embodiment of the present invention may also have the following additional technical features:

[0011] Optionally, the detection module includes a base film, a detection test paper, a sample pad, a quality control test paper and a cover film; the detection test paper is arranged on the base film; the sample pad is partially arranged on the base film, and the sample pad is partially arranged on the detection test paper; the quality control test paper is partially arranged on the base film, and the quality control test paper is partially arranged on the detection test paper, and a gap is left between the quality control test paper and the part of the sample pad arranged on the detection test paper; the cover film is arranged on the base film, and the cover film covers all of the detection test paper and the quality control test paper, and covers part of the sample pad.

[0012] Specifically, the base film, the test paper, the sample pad, the quality control test paper and the cover film are adhered by an adhesive, and the adhesive is made of a transparent material; the base film is made of a transparent material; and the waterproof layer is made of a transparent material.

[0013] Furthermore, the bottom film is bonded to the waterproof layer, and the cover film is bonded to the absorption layer.

[0014] Specifically, the sample pad is fixed with a dry sample processing reagent.

[0015] Specifically, the test paper is immobilized with a dry galactose detection reagent.

[0016] Specifically, the quality control test paper is fixed with a dry water-changing reagent.

[0017] Optionally, the detection module is in the shape of a flat sheet, one side of the detection module is in contact with the waterproof layer, and the other side of the detection module is in contact with the absorption layer.

[0018] Optionally, the detection module is made of flexible material. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic structural diagram of an embodiment of the present utility model;

[0020] Figure 2 A partial cross-sectional view of an embodiment of the present utility model;

[0021] Figure 3 It is a partial cross-sectional view of the detection module according to an embodiment of the present utility model.

[0022] Description of labels

[0023] Diaper body 100 , inner surface layer 101 , absorbent layer 102 , waterproof layer 103 , detection module 200 , sample pad 201 , detection test paper 202 , quality control test paper 203 , bottom film 204 , cover film 205 . DETAILED DESCRIPTION

[0024] The following describes in detail embodiments of the present invention, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to explain the present invention, and should not be construed as limiting the present invention.

[0025] To better understand the above technical solution, exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although exemplary embodiments of the present invention are shown in the accompanying drawings, it should be understood that the present invention can be implemented in various forms and should not be limited by the embodiments described herein. Rather, these embodiments are provided to enable a more thorough understanding of the present invention and to fully convey the scope of the present invention to those skilled in the art.

[0026] like Figures 1 to 3 As shown, a diaper capable of detecting lactose metabolism according to an embodiment of the present invention includes a diaper body 100 and a detection module 200 .

[0027] The diaper body 100 comprises, from inside to outside, an inner layer 101, an absorbent layer 102, and a waterproof layer 103. The inner layer 101 is the surface that contacts the skin. Urine can pass through the inner layer 101 and enter the absorbent layer 102, where it is absorbed by the absorbent material. Some urine will soak the detection module 200. The waterproof layer 103 is made of a transparent material and prevents urine from leaking out.

[0028] The detection module 200 is located between the absorbent layer 101 and the waterproof layer 103 to detect lactose metabolism in urine. The detection module 200 includes a display unit to show detected changes. The detection module 200 is a flat sheet, with one side attached to the waterproof layer 103 and the other to the absorbent layer 102. The detection module 200 is made of a flexible material, which does not affect the firmness of the diaper or the user experience.

[0029] Optionally, the detection module 200 includes a sample pad 201, a test paper 202, a quality control test paper 203, a base film 204 and a cover film 205. The test paper 202 is arranged on the base film 204. Specifically, the test paper 202 is pasted on the base film 204, and the adhesive used is a transparent material, so that the color change can be observed through the base film 204 and the waterproof layer 103. The sample pad 201 is partially arranged on the base film 204, and the sample pad 201 is partially arranged on the test paper 202. The quality control test paper 203 is partially arranged on the base film 204, and the quality control test paper 203 is partially arranged on the test paper 202. There is a gap between the quality control test paper 203 and the portion of the sample pad 201 arranged on the test paper 202, that is, the sample pad 201 and the quality control test paper 203 are respectively placed above the two ends of the test paper 202 and each has an overlapping portion. The total length of the overlapping portion is less than the total length of the test strip 202, meaning that the sample pad 201 and the quality control strip 203 do not directly contact each other. The sample pad 201 and the quality control strip 203 are similarly affixed to the base film 204. A cover film 205 is disposed on the base film 204, covering the entirety of the test strip 202 and the quality control strip 203, as well as a portion of the sample pad 201. This allows urine to soak from one side of the sample pad 201, reacting with the reagents therein while being chromatographed, and ultimately being chromatographed onto the test strip 202, rather than directly soaking the test strip 202.

[0030] The base film 204 and cover film 205 are made of transparent, waterproof, flexible materials. The sample pad 201, test strips 202, and quality control strips 203 are made of soft, absorbent, thin fiber materials. The base film 205 is transparent and can be printed with text or images. Colorimetric areas, QR codes, and other test-related patterns and colors can be set.

[0031] Specifically, the base film 204, the test strip 202, the sample pad 201, the quality control test strip 203, and the cover film 205 are bonded together using a transparent adhesive. The adhesive is also transparent. The base film 204 is also transparent. The waterproof layer 103 is also transparent. The base film 204 is bonded to the waterproof layer 103, and the cover film 205 is bonded to the absorbent layer 101.

[0032] There are one or more detection modules 200 on the diaper body 100, and they are located near the crotch of the diaper body 100. If multiple detection modules 200 are provided, they are distributed along the central axis of the diaper body 100 in the longitudinal direction, or distributed on both sides of the central axis as the axis of symmetry.

[0033] If the detection module 200 is used to detect galactose, the reagents included in each component are as follows: the sample pad 201 contains anti-VC oxidase and buffer. The test strip 202 contains galactose oxidase, peroxidase, 4-aminoantipyrine, 3'5-dichlorodihydroxybenzenesulfonic acid, and buffer. The quality control test strip 203 contains a water-discoloring reagent.

[0034] If the detection module 200 is used to detect lactose, the reagents included in each component are as follows: Sample pad 201 contains anti-VC oxidase, glucose oxidase, and buffer. Test strip 202 contains lactase, glucose oxidase, peroxidase, 4-aminoantipyrine, 3'5-dichlorodihydroxybenzenesulfonic acid, and buffer. Quality control test strip 203 contains a water-discoloring reagent.

[0035] If the detection module 200 is used to detect lactase, the reagents included in each component are as follows: the sample pad 201 contains a buffer solution, the test paper 202 contains 5-bromo-4-chloro-3-indole-β-D-galactoside and a buffer solution, and the quality control test paper 203 contains a water-changing reagent.

[0036] If the detection module 200 is used to detect glucose, the reagents included in each component are as follows: the sample pad 201 contains anti-VC oxidase and buffer. The test strip 202 contains glucose oxidase, peroxidase, 4-aminoantipyrine, 3'5-dichlorodihydroxybenzenesulfonic acid, and buffer. The quality control test strip 203 contains a water-discoloring reagent.

[0037] When the detection module 200 is used to detect galactose, specifically, the sample pad 201 is fixed with a dry sample processing reagent. It is used to remove components in urine that interfere with detection. At the same time, the urine is drained onto the detection test paper. The ingredients of the sample processing reagent are: anti-VC oxidase and buffer. The detection test paper 202 is fixed with a dry galactose detection reagent. It can react with galactose in the sample and produce a color change. The ingredients of the detection reagent are: galactose oxidase, peroxidase, 4-aminoantipyrine, 3'5-dichlorodihydroxybenzenesulfonic acid, and buffer. The quality control test paper 203 is fixed with a dry water-changing reagent. When the detection test paper is soaked, the quality control test paper 203 is also soaked and changes color, which is used to confirm that the detection module has performed the detection and at the same time prompt that the diaper needs to be replaced. The preparation process of the sample pad 201, the detection test paper 202, and the quality control test paper 203 is to first prepare liquid reagents according to their respective formulas, then soak blank absorbent paper in the respective reagents, and then dry and cut them to obtain the corresponding finished products.

[0038] Specifically, when preparing the detection module 200, the sample pad 201 is prepared by: preparing a liquid reagent (180 U / L of anti-VC oxidase, dissolved in phosphate buffer (pH 7.2)); soaking a qualitative filter paper in the reagent at 4°C for 12 hours; removing the filter paper and drying it at 37°C for 4 hours; and cutting it into a sample pad. The test paper 202 is prepared by: preparing a liquid reagent (650 U / L of galactose oxidase, 150 U / L of peroxidase, 0.01% by weight of 4-aminoantipyrine, and 0.15% by weight of 3'5-dichlorodihydroxybenzenesulfonic acid, dissolved in phosphate buffer (pH 7.2)); soaking a qualitative filter paper in the reagent at 4°C for 12 hours; removing the filter paper and drying it at 37°C for 4 hours; and cutting it into a test paper. Quality control test paper 203: Prepare liquid reagent (0.5% by mass of bromocresol green, dissolved in water); soak qualitative filter paper in the reagent at 4°C for 12 hours; remove the filter paper and dry it at 37°C for 4 hours; cut it into quality control test paper.

[0039] The detection module 200 can be equipped with a quality control test strip window, a test strip window, a colorimetric area, and a QR code. The quality control test strip window and the test strip window correspond to the internal quality control test strip 203 and test strip 202, respectively. The colorimetric area contains several color blocks of varying depths for color comparison with the discolored test strip 202. The QR code contains product information and can be used with mobile phone software for scanning, taking photos, and data analysis to better monitor infant lactose metabolism.

[0040] The dry reagent in the detection module 200 displays a corresponding color. The waterproof layer 103 on the outside of the detection module 200 is a transparent material. The guardian can observe the color change on the test paper of the detection module 200 with the naked eye, and compare it with the colorimetric area on the detection module 200 to quickly interpret the result. Furthermore, by scanning the QR code of the detection module 200 with mobile phone software, the test results can be interpreted more accurately, and the test values ​​can be continuously recorded and tracked, thereby monitoring the lactose metabolism of infants and young children over the long term. In addition, the color change of the quality control area of ​​the detection module 200 also indicates that the absorbent layer of the diaper has been soaked, prompting the guardian to change the diaper.

[0041] According to an embodiment of the present invention, a diaper capable of detecting lactose metabolism is provided. After an infant wearing the diaper urinates, the urine passes through the inner surface layer and enters the absorbent layer. A portion of the urine soaks the detection module, which reacts with galactose, lactose, lactase, glucose, and the like in the urine. The detection changes are displayed on the display unit, allowing for rapid interpretation of the results. Therefore, the present invention can quickly and conveniently detect lactose metabolism-related markers in infant urine and monitor the infant's lactose metabolism.

[0042] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like to indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0043] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of the technical features being referred to. Thus, a feature specified as "first" or "second" may explicitly or implicitly include one or more of such features. In the description of this utility model, "plurality" means two or more, unless otherwise specifically defined.

[0044] In this utility model, unless otherwise specified or limited, the terms "installed," "connected," "connect," "fixed," etc. should be understood in a broad sense. For example, they can refer to fixed connection, detachable connection, or integration; mechanical connection, electrical connection; direct connection, indirect connection through an intermediate medium, internal communication between two components, or interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.

[0045] In the present invention, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Moreover, a first feature being "above," "above," and "above" a second feature may include the first feature being directly above or obliquely above the second feature, or may simply mean that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature may include the first feature being directly below or obliquely below the second feature, or may simply mean that the first feature is lower in level than the second feature.

[0046] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic expressions of the above terms should not be understood as necessarily referring to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art can combine and combine different embodiments or examples described in this specification.

[0047] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are illustrative and cannot be understood as limitations on the present invention. Ordinary technicians in this field can change, modify, replace and modify the above embodiments within the scope of the present invention.

Claims

1. A diaper capable of detecting lactose metabolism, characterized in that: include: The diaper body comprises an inner surface layer, an absorbent layer and a waterproof layer arranged in sequence from the inside to the outside; A detection module is located between the absorption layer and the waterproof layer to detect lactose metabolism in urine; the detection module has a display unit to display detection changes.

2. The diaper capable of detecting lactose metabolism according to claim 1, wherein: The detection module includes a base film, a detection test paper, a sample pad, a quality control test paper and a cover film; the detection test paper is arranged on the base film; the sample pad is partially arranged on the base film, and the sample pad is partially arranged on the detection test paper; the quality control test paper is partially arranged on the base film, and the quality control test paper is partially arranged on the detection test paper, and a gap is left between the quality control test paper and the part of the sample pad arranged on the detection test paper; the cover film is arranged on the base film, and the cover film covers the entire detection test paper and the quality control test paper, and covers part of the sample pad.

3. The diaper capable of detecting lactose metabolism according to claim 2, wherein: The base film, the test paper, the sample pad, the quality control test paper and the cover film are adhered by adhesive, and the adhesive is made of a transparent material; the base film is made of a transparent material; and the waterproof layer is made of a transparent material.

4. The diaper capable of detecting lactose metabolism according to claim 3, wherein: The bottom film is adhered to the waterproof layer, and the cover film is adhered to the absorption layer.

5. The diaper capable of detecting lactose metabolism according to claim 2, wherein: The sample pad is fixed with a dry sample processing reagent.

6. The diaper capable of detecting lactose metabolism according to claim 2, wherein: The test paper is fixed with a dry galactose detection reagent.

7. The diaper capable of detecting lactose metabolism according to claim 2, wherein: The quality control test paper is fixed with a dry water-changing reagent.

8. The diaper capable of detecting lactose metabolism according to claim 1, wherein: The detection module is in the shape of a flat sheet. One side of the detection module is in contact with the waterproof layer, and the other side of the detection module is in contact with the absorption layer.

9. The diaper capable of detecting lactose metabolism according to claim 1, wherein: The detection module is made of flexible material.

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