Device for freezing guinea pig trachea through liquid nitrogen spray under bronchoscope

Abstract

The utility model discloses a device for freezing a guinea pig trachea through liquid nitrogen spray under a bronchoscope. A cold source device is mounted at one end of the first pipe body, and a nozzle is mounted at the other end of the first pipe body and extends into a guinea pig air pipe; one end of the second tube body is provided with a display screen, and the other end of the second tube body is provided with a lens which is in signal connection with the display screen and extends into the trachea of the guinea pig. The spray head extends into the trachea of an experimental animal, liquid nitrogen in the liquid nitrogen high-pressure storage tank is sprayed into the trachea of a guinea pig from the spray head through the first pipe body, a freezing experiment can be carried out on the trachea of the guinea pig, meanwhile, the lens also extends into the trachea of the guinea pig, and the lens transmits the freezing condition in the trachea of the guinea pig to the display screen. The freezing condition and the treatment condition in the trachea can be observed on the display screen in real time, the trachea of a guinea pig, a rat, a mouse and other small animals can be effectively subjected to freezing treatment, and the treatment condition can be observed in real time.

Description

Technical Field

[0001] The utility model relates to relevant technical fields such as animal experiments, and in particular to a device for freezing the trachea of ​​a guinea pig by spraying liquid nitrogen under a bronchoscope. Background Art

[0002] Currently, existing airway treatments primarily rely on medication, with limited efficacy. However, recent animal studies have shown that bronchoscopic cryotherapy can destroy diseased tissue cells and kill goblet cells in the airway epithelium, thereby inhibiting chronic airway inflammation. Therefore, using bronchoscopic spray freezing of liquid nitrogen can kill infiltrating inflammatory cells and proliferating goblet cells in the airways of subjects with chronic cough, destroying nerves and cough receptors, thereby inhibiting chronic cough airway inflammation and blocking the formation of the cough hypersensitivity reflex. However, there are currently no tracheal cryotherapy devices for small animals such as guinea pigs, mice, and rats. Utility Model Content

[0003] In view of this, in order to solve the above problems, the purpose of the present invention is to provide a device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy, which includes:

[0004] Cooling source device, first tube body, nozzle, display screen, lens, second tube body;

[0005] The cold source device is installed at one end of the first tube body, and the nozzle is installed at the other end of the first tube body, and the nozzle extends into the guinea pig's trachea;

[0006] The display screen is installed at one end of the second tube body, and the lens is installed at the other end of the second tube body. The lens and the display screen are connected by signal, and the lens extends into the guinea pig's trachea.

[0007] The above-mentioned device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy, wherein the cold source device is a liquid nitrogen high-pressure storage tank.

[0008] In the above-mentioned device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy, a valve is provided at the opening of the liquid nitrogen high-pressure storage tank.

[0009] The above-mentioned device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy further includes: a baffle, which is installed on the valve through a horizontal axis.

[0010] In the above-mentioned device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy, the first tube body and the second tube body are connected by a connecting buckle.

[0011] In the above-mentioned device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy, the nozzle has a trapezoidal cross-section along the horizontal direction, and a plurality of spray ports are provided at one end of the nozzle away from the first tube body.

[0012] Compared with the prior art, the above technical solution has the following positive effects:

[0013] Through the application of the utility model, a device for liquid nitrogen spray freezing of guinea pig trachea under bronchoscopy is provided. The nozzle is inserted into the trachea of ​​the experimental animal, and the liquid nitrogen in the liquid nitrogen high-pressure storage tank is sprayed from the nozzle into the guinea pig trachea through the first tube body, so that the guinea pig trachea can be subjected to a freezing experiment. At the same time, the lens is also inserted into the guinea pig trachea, and the lens transmits the freezing situation in the guinea pig trachea to the display screen. The freezing situation and treatment situation in the trachea can be observed in real time on the display screen. The device has a simple structure, can effectively perform freezing treatment on the trachea of ​​small animals such as guinea pigs, mice and rats, and can observe the treatment situation in the trachea of ​​small animals such as guinea pigs, mice and rats in real time. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 The utility model is a schematic diagram of a device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy.

[0015] 1. Cold source device; 2. First tube body; 3. Nozzle; 4. Display screen; 5. Second tube body; 6. Air pipe; 7. Lens; 8. Valve; 9. Baffle; 10. Connector. DETAILED DESCRIPTION

[0016] The present invention will be further described below with reference to the accompanying drawings and specific implementations, but they are not intended to limit the present invention.

[0017] The structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification so as to facilitate understanding and reading by those familiar with this technology. They are not used to limit the limiting conditions for the implementation of the present invention and therefore have no substantial technical significance. Any modification of the structure, change in the proportional relationship, or adjustment of the size should still fall within the scope of the technical content disclosed in this utility model without affecting the efficacy and purpose of the utility model. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description and are not used to limit the scope of the implementation of the utility model. Changes or adjustments in their relative relationships should also be regarded as the scope of the implementation of the utility model without substantially changing the technical content.

[0018] like Figure 1As shown, a preferred embodiment of a device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy is shown, which includes: a cold source device 1, a first tube body 2, a nozzle 3, a display screen 4, a lens 7, and a second tube body 5.

[0019] A cold source device 1 is installed at one end of the first tube body 2, and a nozzle 3 is installed at the other end of the first tube body 2, and the nozzle 3 extends into the guinea pig trachea 6; a display screen 4 is installed at one end of the second tube body 5, and a lens 7 is installed at the other end of the second tube body 5, and the lens 7 is connected to the display screen 4 signal, and the lens 7 extends into the guinea pig trachea.

[0020] During actual use, the nozzle 3 is inserted into the guinea pig's trachea 6, and the liquid nitrogen in the cold source device can pass through the first tube body 2 and then be sprayed into the guinea pig's trachea 6 through the nozzle 3. At the same time, the lens 7 is also inserted into the guinea pig's trachea 6 to monitor the situation in the guinea pig's trachea 6 in real time, and transmit the freezing situation and treatment situation in the guinea pig's trachea 6 to the display screen 4 in real time. The experimenter can observe the freezing situation and treatment situation in the guinea pig's trachea 6 according to the display screen 4 and record the experimental data in real time.

[0021] The present invention also has the following implementation methods based on the above:

[0022] Furthermore, a device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy is provided, wherein the cold source device 1 is a liquid nitrogen high-pressure storage tank. Specifically, the liquid nitrogen required for the experiment is stored in the liquid nitrogen high-pressure storage tank.

[0023] Furthermore, a device for freezing the trachea of ​​a guinea pig by spraying liquid nitrogen under a bronchoscopy is provided, wherein a valve 8 is provided at the opening of the liquid nitrogen high-pressure storage tank. Specifically, the opening and closing of the liquid nitrogen is controlled by the valve 8.

[0024] Furthermore, a device for freezing the guinea pig's trachea with liquid nitrogen spray under bronchoscopy further includes a baffle 9 mounted on a valve 8 via a horizontal axis. Specifically, due to the high pressure of the liquid nitrogen high-pressure storage tank, the baffle 9 is in a closed state. When the baffle is opened using the valve 8, the liquid nitrogen gas is transported through the first tube 2 to the nozzle 3 located in the airway. The liquid nitrogen gas is evenly sprayed onto the airway wall through the pressure and the cold air, thereby achieving a rapid cooling effect.

[0025] Furthermore, a device for bronchoscopic liquid nitrogen spray freezing of the guinea pig's trachea is provided, wherein the first tube body 2 and the second tube body 5 are connected by a connector 10. Specifically, the connector 10 can be located between the first tube body 2 and the second tube body 5 near the spray head 3 and the lens 7. This allows the lens 7 to observe the freezing and treatment status in real time while the spray head 3 sprays liquid nitrogen to freeze the trachea.

[0026] Furthermore, a device for freezing the trachea of ​​a guinea pig by spraying liquid nitrogen under bronchoscopy is provided, wherein the nozzle 3 has a trapezoidal cross-section along the horizontal direction, and a plurality of spray ports are provided at one end of the nozzle 3 away from the first tube 2. Specifically, liquid nitrogen is sprayed through the spray ports to treat the trachea 6.

[0027] The above description is only a preferred embodiment of the present invention and does not limit the implementation method and protection scope of the present invention. For those skilled in the art, it should be aware that all solutions obtained by equivalent substitutions and obvious changes made using the description and illustrations of the present invention should be included in the protection scope of the present invention.

Claims

1. A device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy, characterized in that: include: Cooling source device, first tube body, nozzle, display screen, lens, second tube body; The cold source device is installed at one end of the first tube body, and the nozzle is installed at the other end of the first tube body, and the nozzle extends into the guinea pig's trachea; The display screen is installed at one end of the second tube body, and the lens is installed at the other end of the second tube body. The lens and the display screen are connected by signal, and the lens extends into the guinea pig's trachea.

2. The device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy according to claim 1, characterized in that: The cold source device is a liquid nitrogen high-pressure storage tank.

3. The device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy according to claim 2, characterized in that: A valve is provided at the opening of the liquid nitrogen high-pressure storage tank.

4. The device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy according to claim 3, characterized in that: Also includes: A baffle is mounted on the valve via a transverse axis.

5. The device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy according to claim 1, characterized in that: The first tube body and the second tube body are connected by a connecting buckle.

6. The device for freezing the guinea pig trachea with liquid nitrogen spray under bronchoscopy according to claim 1, characterized in that: The cross section of the nozzle along the horizontal direction is trapezoidal, and a plurality of injection ports are provided at one end of the nozzle away from the first tube body.

Images