Anti-aging and anti-wrinkle ultrafiltration equipment for concentration preparation of conotoxin

Abstract

The utility model relates to the technical field of ultrafiltration equipment, in particular to anti-aging and anti-wrinkle ultrafiltration equipment for concentration preparation of conotoxin. The technical problems that a hollow fiber membrane filament structure is mostly adopted in the ultrafiltration process of existing conotoxin, due to the fact that vibration of membrane filaments in the ultrafiltration process may be too large, the membrane filaments are prone to being broken in the operation process, leakage and pollution of conotoxin may be caused, and normal operation of equipment is affected are solved. According to the technical scheme, the anti-aging and wrinkle-removing ultrafiltration equipment for conotoxin concentration preparation comprises an ultrafiltration box, a rectangular sealing cover and a water supply box, after an ultrafiltration membrane is turned over, a connecting water pipe is taken out and is in positioning and clamping connection with the ultrafiltration box along an arc-shaped clamping groove, and meanwhile, a second inserting column drives the connecting water pipe to be fixedly connected with a water outlet pipe through a second inserting hole; then a water source is poured into the water supply tank through the water inlet pipe, enters the water outlet pipe to reach the connecting water pipe through driving of the water pump, and flushes the ultrafiltration membrane through the spray head.

Description

TECHNICAL FIELD

[0001] The utility model relates to ultrafiltration equipment technical field especially relates to a kind of anti-aging wrinkle's conotoxin concentration preparation with ultrafiltration equipment. BACKGROUND

[0002] Conotoxin is a kind of biological neurotoxin extracted from the venom gland of marine gastropods Conus, it is composed of many single peptides, and the main component is active polypeptide chemical substance with high specificity to certain calcium channels and nervous system receptors, conotoxin can inhibit the generation of facial fine lines, improve skin laxity, improve skin elasticity, and fade fine lines, so it is widely used in the field of beauty, it can inhibit swelling, restore skin elasticity, thereby improve skin quality and fine line depth, as a kind of anti-aging agent, conotoxin has strong anti-aging effect, and conotoxin needs to be concentrated and purified in production process, the existing conotoxin mostly adopts hollow fiber membrane silk structure in ultrafiltration process, since the vibration of membrane silk in ultrafiltration process can be too large, the membrane silk is prone to breakage in operation, which can cause conotoxin leakage and pollution, thereby affecting the normal operation of equipment. SUMMARY

[0003] To overcome the problem that the existing conotoxin mostly adopts hollow fiber membrane silk structure in ultrafiltration process, since the vibration of membrane silk in ultrafiltration process can be too large, the membrane silk is prone to breakage in operation, which can cause conotoxin leakage and pollution, thereby affecting the normal operation of equipment.

[0004] The technical scheme of the utility model is: a kind of anti-aging wrinkle's conotoxin concentration preparation with ultrafiltration equipment, including ultrafiltration box, rectangular sealing cover and water supply tank;The upper portion of ultrafiltration box is equipped with rectangular sealing cover for sealing ultrafiltration box and facilitating opening to clean the inside of ultrafiltration box, one side of ultrafiltration box is equipped with water supply tank for supplying water source to clean the inside of ultrafiltration box to avoid affecting ultrafiltration effect.

[0005] Preferably, when cone snail toxin enters the ultrafiltration box, it is first preliminarily filtered through the porous filter plate to remove large particles, suspended matter, microorganisms and other impurities to prevent these impurities from clogging or damaging the ultrafiltration membrane. Then, further ultrafiltration is carried out through the ultrafiltration membrane. As a high-molecular active ingredient, cone snail toxin can be separated from small molecular substances by the ultrafiltration membrane. After separation, it flows into the container through the liquid outlet pipe for storage, which is convenient for the next step of the process. In this process, the column firmly supports the ultrafiltration box. When all ultrafiltration is completed, the rectangular sealing cover is opened by lifting the handle. The porous filter plate is positioned and connected to the ultrafiltration box along the rectangular clamping groove through the rectangular clamping block. The porous filter plate can be taken out and cleaned to avoid affecting the filtering effect of the porous filter plate. Then, the rotating shaft drives the rectangular frame to rotate through the drive of the motor, so that the ultrafiltration membrane is flipped so that the side with residual matter faces downward, which is convenient for subsequent cleaning.

[0006] Preferably, a liquid outlet pipe is installed at the lower end of the ultrafiltration box, and columns are installed at the external corners of the liquid outlet pipe. Multiple groups of first plug holes for positioning and connecting rectangular sealing covers are opened laterally symmetrically on both sides of the upper side of the ultrafiltration box, and rectangular card slots are opened laterally symmetrically on both sides of the inner wall of the ultrafiltration box. When cone snail toxin enters the ultrafiltration box, it is first preliminarily filtered through the porous filter plate to remove large particulate matter, suspended matter, microorganisms and other impurities to prevent these impurities from clogging or damaging the ultrafiltration membrane.

[0007] Preferably, one side of the inner wall of the ultrafiltration box is provided with two groups of rectangular snap-in grooves with an arc-shaped snap-in groove between them, and the inner wall of the ultrafiltration box is provided with a connecting hole corresponding to the arc-shaped snap-in groove on the side away from the arc-shaped snap-in groove. The inner side of the ultrafiltration box is provided with an ultrafiltration membrane, and the outer side of the ultrafiltration membrane is provided with a rectangular frame. Then, further ultrafiltration is performed through the ultrafiltration membrane. As a high-molecular active ingredient, conotoxin can be separated from small-molecule substances through the ultrafiltration membrane. After separation, it flows into the container through the outlet pipe for storage, which is convenient for the next step.

[0008] Preferably, rotating shafts passing through the ultrafiltration box are symmetrically installed on both sides of the rectangular frame, and a motor is installed on the end of the rotating shaft away from the rectangular frame. A porous filter plate is provided above the ultrafiltration membrane, and two groups of rectangular clamping blocks are installed laterally symmetrically on both sides of the porous filter plate. The rectangular clamping blocks drive the porous filter plate to be positioned and clamped with the ultrafiltration box along the rectangular clamping groove. During this process, the columns provide firm support for the ultrafiltration box. When all ultrafiltration is completed and the porous filter plate is taken out, the rotating shaft drives the rectangular frame to rotate through the drive of the motor, thereby flipping the ultrafiltration membrane so that the side with residual matter faces downward, which is convenient for subsequent cleaning.

[0009] Preferably, a liquid inlet pipe is installed in the middle of the upper end of the rectangular sealing cover, and handles fixedly connected to the rectangular sealing cover are symmetrically provided on both sides of the liquid inlet pipe. A rectangular sealing ring is installed at the lower end of the rectangular sealing cover corresponding to the inner wall of the ultrafiltration box, and first plug-in posts are installed at the edges of both sides of the lower end of the rectangular sealing cover corresponding to the first plug-in holes. The first plug-in posts drive the rectangular sealing cover to be positioned and connected to the ultrafiltration box through the first plug-in holes. At the same time, the rectangular sealing ring is fitted and connected along the inner wall of the ultrafiltration box to increase the sealing of the ultrafiltration box. Then, the cone snail toxin is poured into the ultrafiltration box through the liquid inlet pipe for ultrafiltration. When all ultrafiltration is completed, the rectangular sealing cover is opened by lifting the handle, and the porous filter plate is positioned and connected to the ultrafiltration box along the rectangular plug-in groove through the rectangular plug-in block. The porous filter plate can be taken out and cleaned to avoid affecting the filtering effect of the porous filter plate.

[0010] Preferably, a water pump is installed at a corner of one side of the water supply tank, a water inlet pipe is installed at a corner of the side of the water supply tank away from the ultrafiltration tank, a water outlet pipe is installed at the middle part of the upper end of the water supply tank, the outlet pipe is fixedly connected to the ultrafiltration tank through a connecting hole, and a plurality of second plug holes for the second plug column to pass through are arranged around the edge of one end of the outlet pipe away from the water supply tank, and a connecting water pipe is provided at the end of the outlet pipe away from the water supply tank, and the connecting water pipe is positioned and connected to the ultrafiltration tank along the arc-shaped plug groove. When the ultrafiltration membrane is flipped, the connecting water pipe is taken out and positioned and connected to the ultrafiltration tank along the arc-shaped plug groove. At the same time, the second plug column drives the connecting water pipe to be fixedly connected to the outlet pipe through the second plug hole. Then the water source is poured into the water supply tank through the inlet pipe. Driven by the water pump, the water source enters the outlet pipe from the water supply tank to the connecting water pipe, and is flushed to the ultrafiltration membrane through the nozzle.

[0011] Preferably, a second plug-in column is installed at the edge of one end of the connecting water pipe close to the water outlet pipe corresponding to the second plug-in hole, and multiple groups of connecting shafts are installed horizontally at the lower end of the connecting water pipe. A nozzle is provided below the connecting shaft, and the nozzle is rotatably connected to the connecting water pipe through the connecting shaft. A rotating driver is installed on one side of the connecting shaft. During this process, the nozzle is driven by the rotating driver to be rotatably connected to the connecting water pipe through the connecting shaft, thereby expanding the cleaning area and cleaning the ultrafiltration membrane from the reverse direction, thereby effectively removing dirt on the membrane surface and restoring the filtration performance of the membrane.

[0012] Beneficial effects of the utility model:

[0013] 1. According to the previous ultrafiltration process of cone snail toxins, hollow fiber membrane structures are mostly used. Since the vibration of the membrane wire may be too large during the ultrafiltration process, the membrane wire is prone to breakage during operation, which may cause the leakage and contamination of cone snail toxins, thereby affecting the normal operation of the equipment. The difference is that when cone snail toxins enter the ultrafiltration box, they are first filtered through the porous filter plate to remove large particles, suspended matter, microorganisms and other impurities to prevent these impurities from clogging or damaging the ultrafiltration membrane. Then, further ultrafiltration is carried out through the ultrafiltration membrane. As a high-molecular active ingredient, cone snail toxins can pass through the ultrafiltration membrane. It can achieve separation from small molecular substances. After the separation is completed, it flows into the container through the liquid outlet pipe for storage, which is convenient for the next step. In this process, the column firmly supports the ultrafiltration box. When all ultrafiltration is completed, the rectangular sealing cover is opened by lifting the handle. The hole filter plate is positioned and connected with the ultrafiltration box along the rectangular clamping groove through the rectangular clamping block. The hole filter plate can be taken out and cleaned to avoid affecting the filtering effect of the hole filter plate. Then, the motor drives the rotating shaft to drive the rectangular frame to rotate, so that the ultrafiltration membrane is flipped so that the side with residual substances is facing down, which is convenient for subsequent cleaning.

[0014] 2. After the ultrafiltration membrane is flipped, take out the connecting water pipe and position it along the arc-shaped connecting groove with the ultrafiltration box. At the same time, the second connecting column drives the connecting water pipe to be fixedly connected to the outlet pipe through the second connecting hole. Then pour the water source into the water supply tank through the water inlet pipe. Driven by the water pump, the water source enters the outlet pipe from the water supply tank to the connecting water pipe, and is flushed towards the ultrafiltration membrane through the nozzle. In this process, the nozzle is driven by the rotating driver to rotate and connect with the connecting water pipe through the connecting shaft, thereby expanding the cleaning area and cleaning the ultrafiltration membrane from the reverse direction, thereby effectively removing dirt on the membrane surface and restoring the filtration performance of the membrane. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is an exploded schematic diagram of the overall structure of the utility model;

[0016] Figure 2 This is an exploded schematic diagram of the ultrafiltration box structure of the present utility model;

[0017] Figure 3 This is a schematic diagram of the rectangular sealing cover structure of the present utility model;

[0018] Figure 4 This is an exploded schematic diagram of the water supply tank structure of the present utility model.

[0019] Explanation of the accompanying drawings: 1. Ultrafiltration box; 2. Rectangular sealing cover; 3. Water supply box; 101. Liquid outlet pipe; 102. Column; 103. Connecting hole; 104. First plug-in hole; 105. Arc-shaped snap-in groove; 106. Rectangular snap-in groove; 107. Rectangular frame; 108. Ultrafiltration membrane; 109. Rotating shaft; 110. Motor; 111. Rectangular snap-in block; 112. Porous filter plate; 201. Liquid inlet pipe; 202. Handle; 203. Rectangular sealing ring; 204. First plug-in column; 301. Water pump; 302. Water inlet pipe; 303. Water outlet pipe; 304. Second plug-in hole; 305. Second plug-in column; 306. Connecting water pipe; 307. Connecting rotating shaft; 308. Rotating drive; 309. Spray nozzle. DETAILED DESCRIPTION

[0020] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0021] See also Figure 1-2 The utility model provides an embodiment: an ultrafiltration device for preparing concentrated cone snail toxins for anti-aging and wrinkle removal, comprising an ultrafiltration box 1, a rectangular sealing cover 2 and a water supply box 3; a rectangular sealing cover 2 for sealing the ultrafiltration box 1 and conveniently opening the interior of the ultrafiltration box 1 for cleaning is provided on the top of the ultrafiltration box 1, a water supply box 3 for supplying water to clean the interior of the ultrafiltration box 1 to avoid affecting the ultrafiltration effect is provided on one side of the ultrafiltration box 1, a liquid outlet pipe 101 is installed at the lower end of the ultrafiltration box 1, and columns 102 are installed at the external corners of the liquid outlet pipe 101, a plurality of groups of first plug holes 104 for positioning and connecting the rectangular sealing cover 2 are symmetrically provided on both sides of the upper side of the ultrafiltration box 1, rectangular clamping grooves 106 are symmetrically provided on both sides of the inner wall of the ultrafiltration box 1, and two groups of rectangular An arc-shaped snap-fitting groove 105 is provided between the snap-fitting grooves 106, and a connecting hole 103 is provided on the inner wall of the ultrafiltration box 1 away from the side of the arc-shaped snap-fitting groove 105 corresponding to the arc-shaped snap-fitting groove 105. An ultrafiltration membrane 108 is provided on the inner side of the ultrafiltration box 1. The material of the ultrafiltration membrane 108 is polyvinylidene fluoride, and a rectangular frame 107 is provided on the outer side of the ultrafiltration membrane 108. Rotating shafts 109 passing through the ultrafiltration box 1 are symmetrically installed on both sides of the rectangular frame 107. A motor 110 is installed on one end of the rotating shaft 109 away from the rectangular frame 107. A porous filter plate 112 is provided above the ultrafiltration membrane 108, and two groups of rectangular snap-fitting blocks 111 are laterally symmetrically installed on both sides of the porous filter plate 112. The rectangular snap-fitting blocks 111 drive the porous filter plate 112 to be positioned and snap-fitted with the ultrafiltration box 1 along the rectangular snap-fitting groove 106.

[0022] See also Figure 3-4In this embodiment, a liquid inlet pipe 201 is installed in the middle of the upper end of the rectangular sealing cover 2, and handles 202 fixedly connected to the rectangular sealing cover 2 are symmetrically provided on both sides of the liquid inlet pipe 201. A rectangular sealing ring 203 is installed at the lower end of the rectangular sealing cover 2 corresponding to the inner wall of the ultrafiltration box 1, and first plug-in columns 204 are installed at the edges of both sides of the lower end of the rectangular sealing cover 2 corresponding to the first plug-in holes 104. A water pump 301 is installed at the corner of one side of the water supply box 3, and a water inlet pipe 302 is installed at the corner of the side of the water supply box 3 away from the ultrafiltration box 1. A water outlet pipe 303 is installed in the middle of the upper end of the water supply box 3, and the water outlet pipe 303 is fixedly connected to the ultrafiltration box 1 through the connecting hole 103. The water outlet pipe 303 is away from the supply box A plurality of second plug holes 304 for the second plug columns 305 to pass through are provided around the edge of one end of the water tank 3. A connecting water pipe 306 is provided at the end of the water outlet pipe 303 away from the water supply tank 3. The connecting water pipe 306 is positioned and connected with the ultrafiltration box 1 along the arc-shaped clamping groove 105. A second plug column 305 is installed at the edge of one end of the connecting water pipe 306 close to the water outlet pipe 303 corresponding to the second plug hole 304. A plurality of connecting shafts 307 are horizontally installed at the lower end of the connecting water pipe 306. A nozzle 309 is provided below the connecting shaft 307. The nozzle 309 is rotatably connected to the connecting water pipe 306 through the connecting shaft 307, and a rotation driver 308 is installed on one side of the connecting shaft 307.

[0023] During operation, the first plug-in column 204 drives the rectangular sealing cover 2 to be positioned and connected with the ultrafiltration box 1 through the first plug-in hole 104. At the same time, the rectangular sealing ring 203 is fitted along the inner wall of the ultrafiltration box 1 to increase the sealing performance of the ultrafiltration box 1. Then, the conus toxin is poured into the ultrafiltration box 1 through the liquid inlet pipe 201 for ultrafiltration.

[0024] When the conotoxin enters the ultrafiltration box 1, it is first preliminarily filtered through the porous filter plate 112 to remove impurities such as large particles, suspended matter, and microorganisms to prevent these impurities from clogging or damaging the ultrafiltration membrane 108. Then, further ultrafiltration is performed through the ultrafiltration membrane 108. As a high-molecular active ingredient, the conotoxin can be separated from small molecules by the ultrafiltration membrane 108. After separation, it flows into a container through the liquid outlet pipe 101 for storage, which is convenient for the next step. During this process, the column 102 provides a stable support to the ultrafiltration box 1;

[0025] When all ultrafiltration is completed, the rectangular sealing cover 2 is opened by lifting the handle 202, and the porous filter plate 112 is positioned and connected to the ultrafiltration box 1 along the rectangular clamping groove 106 through the rectangular clamping block 111. The porous filter plate 112 can be taken out and cleaned to avoid affecting the filtering effect of the porous filter plate 112. Then, the motor 110 drives the rotating shaft 109 to rotate the rectangular frame 107, thereby turning the ultrafiltration membrane 108 over so that the side with residual substances faces downward, which is convenient for subsequent cleaning.

[0026] When the ultrafiltration membrane 108 is turned over, the connecting water pipe 306 is taken out and is positioned and clamped along the arc-shaped clamping groove 105 and the ultrafiltration box 1, meanwhile the second plug-in column 305 drives the connecting water pipe 306 to be fixedly connected with the water outlet pipe 303 through the second plug-in hole 304, then the water source is poured into the water supply box 3 through the water inlet pipe 302, under the driving of the water pump 301, the water source enters the water outlet pipe 303 from the water supply box 3 to the connecting water pipe 306, and the ultrafiltration membrane 108 is washed through the spray head 309, in the process, the spray head 309 is rotationally connected with the connecting water pipe 306 through the connecting shaft 307 by driving the rotating driver 308, thereby expanding the cleaning area, and the ultrafiltration membrane 108 is cleaned from the opposite direction, so that the dirt on the membrane surface is effectively removed, and the filtering performance of the membrane is recovered.

[0027] Through the above steps, when the conotoxin enters the ultrafiltration box 1, the large-particle substances, suspended matters, microorganisms and other impurities are removed through the hole filter plate 112 for preliminary filtration, so as to prevent the impurities from causing blockage or damage to the ultrafiltration membrane 108, then the conotoxin is further ultrafiltrated through the ultrafiltration membrane 108, the conotoxin as a high-molecular active component can be separated from small-molecule substances through the ultrafiltration membrane 108, after the separation is completed, the liquid outlet pipe 101 flows to the container for storage, so that the next process is facilitated, in the process, the stand 102 stably supports the ultrafiltration box 1, when the ultrafiltration is completed, the handle 202 is lifted, the rectangular sealing cover 2 is opened, the hole filter plate 112 is positioned and clamped along the rectangular clamping groove 106 and the ultrafiltration box 1 through the rectangular clamping block 111, so that the hole filter plate 112 can be taken out and cleaned, so as to avoid affecting the filtering effect of the hole filter plate 112, then the rectangular frame 107 is driven to rotate by the motor 110, so that the ultrafiltration membrane 108 is turned over, so that the one side of the residual substances faces downward, and the subsequent cleaning is facilitated.

[0028] The embodiments of the utility model are described in detail above combined with the drawings, but the utility model is not limited to the above-mentioned embodiments, and various changes can be made within the knowledge range of the person skilled in the art without departing from the purpose of the utility model.

Claims

1. An ultrafiltration device for conus toxin concentration and preparation for anti-aging and wrinkle-removing, comprising an ultrafiltration box (1); characterized in that: The invention also includes a rectangular sealing cover (2) and a water supply box (3); a rectangular sealing cover (2) for sealing the ultrafiltration box (1) and conveniently opening to clean the interior of the ultrafiltration box (1) is provided above the ultrafiltration box (1); and a water supply box (3) for supplying water to clean the interior of the ultrafiltration box (1) to avoid affecting the ultrafiltration effect is provided on one side of the ultrafiltration box (1).

2. The ultrafiltration device for conotoxin concentration and preparation for anti-aging and anti-wrinkle according to claim 1, characterized in that: A liquid outlet pipe (101) is installed at the lower end of the ultrafiltration box (1), and columns (102) are installed at the outer corners of the liquid outlet pipe (101). Multiple groups of first plug holes (104) for positioning and connecting the rectangular sealing cover (2) are symmetrically opened on both sides of the upper side of the ultrafiltration box (1), and rectangular clamping grooves (106) are symmetrically opened on both sides of the inner wall of the ultrafiltration box (1).

3. The ultrafiltration device for conotoxin concentration and preparation for anti-aging and anti-wrinkle according to claim 2, characterized in that: One side of the inner wall of the ultrafiltration box (1) is provided with two groups of rectangular clamping grooves (106), between which an arc-shaped clamping groove (105) is provided. A connecting hole (103) is provided on the side of the inner wall of the ultrafiltration box (1) away from the arc-shaped clamping groove (105) and corresponding to the arc-shaped clamping groove (105). An ultrafiltration membrane (108) is provided on the inner side of the ultrafiltration box (1), and a rectangular frame (107) is provided on the outer side of the ultrafiltration membrane (108).

4. The ultrafiltration device for conotoxin concentration and preparation for anti-aging and anti-wrinkle according to claim 2, characterized in that: Rotating shafts (109) passing through the ultrafiltration box (1) are symmetrically mounted on both sides of the rectangular frame (107); a motor (110) is mounted on one end of the rotating shaft (109) away from the rectangular frame (107); a porous filter plate (112) is disposed above the ultrafiltration membrane (108); two groups of rectangular clamping blocks (111) are symmetrically mounted on both sides of the porous filter plate (112); the rectangular clamping blocks (111) drive the porous filter plate (112) to be positioned and clamped with the ultrafiltration box (1) along the rectangular clamping groove (106).

5. The ultrafiltration device for conotoxin concentration and preparation for anti-aging and anti-wrinkle according to claim 2, characterized in that: A liquid inlet pipe (201) is installed in the middle of the upper end of the rectangular sealing cover (2), and handles (202) fixedly connected to the rectangular sealing cover (2) are symmetrically provided on both sides of the liquid inlet pipe (201). A rectangular sealing ring (203) is installed at the lower end of the rectangular sealing cover (2) corresponding to the inner wall of the ultrafiltration box (1), and first plug-in columns (204) are installed at the edges of both sides of the lower end of the rectangular sealing cover (2) corresponding to the first plug-in holes (104).

6. The ultrafiltration device for conus toxin concentration and preparation for anti-aging and anti-wrinkle according to claim 3, characterized in that: A water pump (301) is installed at a corner of one side of the water supply box (3), a water inlet pipe (302) is installed at a corner of a side of the water supply box (3) away from the ultrafiltration box (1), a water outlet pipe (303) is installed at the middle of the upper end of the water supply box (3), the water outlet pipe (303) is fixedly connected to the ultrafiltration box (1) through the connecting hole (103), a plurality of groups of second plug holes (304) for the second plug columns (305) to pass through are arranged around the edge of one end of the water outlet pipe (303) away from the water supply box (3), a connecting water pipe (306) is provided at one end of the water outlet pipe (303) away from the water supply box (3), and the connecting water pipe (306) is positioned and connected to the ultrafiltration box (1) along the arc-shaped connecting groove (105).

7. The ultrafiltration device for conotoxin concentration and preparation for anti-aging and anti-wrinkle according to claim 6, characterized in that: A second plug-in column (305) is installed at the edge of one end of the connecting water pipe (306) close to the water outlet pipe (303) corresponding to the second plug-in hole (304). A plurality of connecting shafts (307) are installed transversely at the lower end of the connecting water pipe (306). A nozzle (309) is provided below the connecting shaft (307). The nozzle (309) is rotatably connected to the connecting water pipe (306) through the connecting shaft (307). A rotation driver (308) is installed on one side of the connecting shaft (307).

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