Anesthesia maintaining and fixing device and X-ray radiography anesthesia system

By designing an adjustable fixation plate and anesthesia mask device, the problems of flexible adjustment and anesthesia maintenance in the anteroposterior and lateral X-rays of the long bones of the experimental mice's limbs were solved, achieving efficient and clear X-ray imaging.

CN223453246UActive Publication Date: 2025-10-21INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES
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Patent Information

Application Number
CN202421957379.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-13
Publication Date
2025-10-21
Estimated Expiration
2034-08-13

AI Technical Summary

Technical Problem

The existing laboratory fixation board cannot flexibly adjust the body position for anteroposterior and lateral X-rays of the long bones of the limbs, and the experimental mice cannot maintain anesthesia during the X-ray process, resulting in unclear or distorted images.

Method used

A device consisting of a fixing plate, multiple fixing rods and an anesthesia mask was designed. The sliding grooves and fixing rods on the fixing plate can adjust the angle and position of the experimental mouse's limbs. The anesthesia mask keeps the experimental mouse in an anesthetized state during X-ray filming. Combined with a transparent anesthesia induction device, it facilitates independent operation.

Benefits of technology

It realizes the flexible adjustment of the fixed angles of the experimental mouse's limbs to meet the needs of shooting anteroposterior and lateral X-ray films, avoids unclear or deformed imaging caused by twisting of the animal's body, and improves the clarity of X-ray imaging and the convenience of operation.

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Abstract

The utility model relates to an anesthesia maintaining and fixing device and an X-ray radiography anesthesia system.The anesthesia maintaining and fixing device comprises a fixing plate, first sliding grooves extending in the front-back direction are formed in the left end and the right end of the fixing plate respectively, and second sliding grooves extending in the left-right direction are formed in the front end and the rear end of the fixing plate respectively; the fixing rods are slidably mounted on the first sliding grooves and the second sliding grooves respectively and used for fixing the four limbs of the laboratory mouse; the anaesthetic mask is mounted in the middle of the front end of the fixing plate. Thus, a plurality of fixing rods and sliding grooves are arranged on the fixing plate, the fixing angles and positions of the four limbs of the laboratory mouse can be flexibly adjusted by adjusting the positions of the fixing rods, and the shooting requirements of positive and lateral X-ray plain films of long bones of the four limbs are met. The laboratory mouse is kept in an anesthesia maintaining state in the X-ray radiography process through the anaesthetic mask, and unclear X-ray imaging or deformation caused by twisting of an animal body is avoided.
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Description

TECHNICAL FIELD

[0001] The present disclosure relates to the technical field of animal medical experiment auxiliary equipment, in particular, to an anesthesia maintaining and fixing device and an X-ray photographing anesthesia system. BACKGROUND

[0002] In the X-ray photographing process, the animal needs to be anesthetized and fixed. The experimental mouse fixing plate commonly used in the laboratory cannot flexibly adjust the body position required for the X-ray photographing of the long bones of the limbs in the front and side positions. The traditional device can only take the side position X-ray photograph of the long bones of the limbs of the experimental mouse, and cannot meet the requirement of taking the front position X-ray photograph. Moreover, the animal cannot be kept in the anesthetized state during the X-ray photographing process of the experimental mouse, and the body of the animal twists, resulting in unclear or deformed X-ray imaging. CONTENT OF THE UTILITY MODEL

[0003] The purpose of the present disclosure is to provide an anesthesia maintaining and fixing device and an X-ray photographing anesthesia system to at least partially solve the problems in the related art.

[0004] In order to achieve the above-mentioned purpose, the present disclosure provides an anesthesia maintaining and fixing device, comprising:

[0005] a fixing plate, two ends of the fixing plate are respectively formed with first sliding grooves extending in the front and back directions, and two ends of the fixing plate are respectively formed with second sliding grooves extending in the left and right directions;

[0006] a plurality of fixing rods, respectively and slidably installed on the first sliding grooves and the second sliding grooves, for fixing the limbs of the experimental mouse; and

[0007] an anesthesia mask, installed at the middle part of the front end of the fixing plate.

[0008] Optionally, two first sliding grooves are arranged at the left and right ends of the fixing plate, two second sliding grooves are arranged at the front and back ends of the fixing plate, and the anesthesia mask is installed between the two second sliding grooves at the front end of the fixing plate.

[0009] Optionally, an elastic rope is installed on each of the fixing rods, and the end of the elastic rope away from the fixing rod is used for fixing the limbs of the experimental mouse.

[0010] Optionally, a grid line is drawn on the fixing plate.

[0011] Optionally, a scale is installed on the fixing plate in the left and right directions and / or the front and back directions.

[0012] Optionally, a dot-shaped protrusion is formed at the scale of the scale.

[0013] Optionally, a plurality of fixing belts are connected to the anesthesia mask, and the fixing belts are sleeved on the fixing plate.

[0014] Optionally, an end of one side of the anesthesia mask is provided with a plurality of folding portions which can be folded in multiple sections, and the folding portions are configured to be folded upward to form an arc-shaped opening.

[0015] Optionally, a ventilation hole is formed in the anesthesia mask, and a cover is arranged on the ventilation hole.

[0016] According to a second aspect of the present disclosure, an X-ray radiography anesthesia system is also provided, which comprises an anesthesia induction device and the anesthesia maintenance and fixing device described above.

[0017] By the above technical solution, the plurality of fixing rods and sliding grooves are arranged on the fixing plate, and the angle and position of the limbs of the experimental mouse can be flexibly adjusted by adjusting the position of the fixing rods, so as to meet the shooting requirements of the anteroposterior and lateral X-ray radiography of the long bones of the limbs.

[0018] Other features and advantages of the present disclosure will be described in detail in the following specific embodiments. BRIEF DESCRIPTION OF DRAWINGS

[0019] The accompanying drawings are included to provide a further understanding of the present disclosure and constitute a part of the specification, and are used together with the following specific embodiments to explain the present disclosure, but do not constitute a limitation on the present disclosure. In the drawings:

[0020] Figure 1 is a structural schematic diagram of the anesthesia maintenance and fixing device provided by an exemplary embodiment of the present disclosure;

[0021] Figure 2 is a structural schematic diagram of the anesthesia mask in the anesthesia maintenance and fixing device provided by an exemplary embodiment of the present disclosure;

[0022] Figure 3 is a structural schematic diagram of the anesthesia induction device provided by an exemplary embodiment of the present disclosure.

[0023] LEGEND DESCRIPTION

[0024] 1 - fixed plate; 11 - first sliding groove; 12 - second sliding groove; 2 - fixed rod; 21 - elastic rope; 3 - anesthesia mask; 31 - fixing belt; 32 - arc-shaped opening; 33 - folding part; 34 - traction rope; 35 - air hole; 36 - breathing part; 37 - first connecting pipe; 38 - first flow regulating valve; 4 - grid line; 5 - scale; 6 - anesthesia induction device; 61 - hand rod; 7 - second connecting pipe; 8 - anesthesia bottle; 9 - second flow regulating valve DETAILED DESCRIPTION

[0025] The specific embodiments of the present disclosure are described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are only used to illustrate and explain the present disclosure, and are not used to limit the present disclosure.

[0026] In the present disclosure, the orientation words "upper", "lower", "top", "bottom" are defined based on the actual direction of use of the relevant components. "Inner", "outer" is in terms of the contour of the corresponding parts themselves. The purpose of using the terms "first", "second", etc. is to distinguish different components, and does not have sequentiality and importance. In the present disclosure, when the following description refers to the drawings, the same numbers in different drawings represent the same or similar elements, unless otherwise indicated.

[0027] Referring to Figures 1 to 3 The present disclosure provides an anesthesia maintenance and fixing device, which can include a fixed plate 1, a plurality of fixed rods 2, and an anesthesia mask 3. The left and right ends of the fixed plate 1 are respectively formed with first sliding grooves 11 extending in the front-rear direction, and the front and rear ends of the fixed plate 1 are respectively formed with second sliding grooves 12 extending in the left-right direction. The plurality of fixed rods 2 are respectively slidably installed on the first sliding grooves 11 and the second sliding grooves 12, for fixing the limbs of the experimental mouse. The limbs of the experimental mouse are fixed to the fixed rods 2 on the first sliding grooves 11, and the lateral film of the long bones of the limbs of the experimental mouse can be taken. The limbs of the experimental mouse are fixed to the fixed rods 2 on the second sliding grooves 12, and the frontal film of the long bones of the limbs of the experimental mouse can be taken. The anesthesia mask 3 is installed at the middle of the front end of the fixed plate 1.

[0028] Through the above technical solution, a plurality of fixed rods and sliding grooves are provided on the fixed plate. By adjusting the position of the fixed rod, the angle and position of the experimental mouse limbs can be flexibly adjusted to meet the shooting requirements of the long bone X-ray film. The experimental mouse remains in an anesthesia maintenance state during X-ray photography through the anesthesia mask, avoiding unclear or deformed X-ray imaging due to animal body twisting.

[0029] Specifically, referring to Figure 1The left and right ends of the fixing plate 1 are respectively provided with two first sliding grooves 11 arranged at intervals, and the front and back ends of the fixing plate 1 are respectively provided with two second sliding grooves 12 arranged at intervals. The anesthesia mask 3 is installed between the two second sliding grooves 12 at the front end of the fixing plate 1. When shooting the lateral film of the long bones of the limbs of the experimental mouse, the limbs of the experimental mouse can be fixed to the fixing rods 2 on the four first sliding grooves 11; when shooting the frontal film of the long bones of the limbs of the experimental mouse, the limbs of the experimental mouse are fixed to the fixing rods 2 on the four second sliding grooves 12.

[0030] The fixing plate commonly used in the laboratory at present needs to be bound with ropes or rubber bands and the like to fix the limbs of the experimental mouse, which is troublesome, time-consuming, easy to fall off, cannot be flexibly adjusted in length, and is not firm, and cannot quickly complete X-ray shooting. In the embodiments of the present disclosure, referring to Figure 1 , the elastic ropes 21 can be installed on each fixing rod 2, and the ends of the elastic ropes 21 away from the fixing rod 2 are used to fix the limbs of the experimental mouse. The elastic ropes 21 are used to fix the limbs of the experimental mouse, one end of the elastic rope 21 is bound on the fixing rod 2, the other end is sleeved on the joint at the end of the limbs, and then a spring buckle is used for locking, which is simple and fast in operation, can be flexibly adjusted in length, and is firm.

[0031] In some embodiments, referring to Figure 1 , the grid lines 4 can be drawn on the fixing plate 1, which can provide position information for fixing the experimental mouse and ensure that the position of the experimental mouse is consistent. In the embodiments of the present disclosure, the surface of the fixing plate 1 can be drawn with three longitudinally arranged grid lines and a plurality of transversely arranged grid lines, the middle longitudinal grid line can identify the central axis of the animal body, and the other two longitudinal grid lines can identify the position of the end joint of the animal limb abduction position.

[0032] In some embodiments, referring to Figure 1 , the fixing plate 1 can be provided with a scale 5 in the left-right direction and / or the front-back direction, and the scale 5 can provide scale information after X-ray imaging. Specifically, the scale 5 is provided with a bending part on both sides, which can be clamped on the end of the fixing plate 1, facilitating installation and disassembly. The present disclosure does not limit the position of the scale 5, and the scale 5 can be installed at any position of the fixing plate according to actual needs.

[0033] Further, the scale 5 can be provided with a dot-shaped protrusion at the scale. Specifically, the scale 5 is made of metal, and a dot-shaped protrusion is formed at every 1cm scale on the scale 5, so as to be imaged during X-ray photography, thereby providing scale information.

[0034] As an exemplary embodiment of the present disclosure, referring to Figure 2The anesthesia mask 3 can be connected with a plurality of fixing bands 31, which are sleeved on the fixing plate 1. Specifically, the fixing bands 31 can be made of silica gel, and the position of the anesthesia mask 3 can be fixed by the fixing bands 31. The anesthesia mask 3 can be provided with hooks for mounting the fixing bands 31, and the ends of the plurality of fixing bands 31 away from the anesthesia mask 3 can be provided with buckles, and the ends of the plurality of fixing bands 31 away from the anesthesia mask 3 can be connected by the buckles at the bottom end of the fixing plate 1.

[0035] According to an exemplary embodiment of the present disclosure, referring to Figure 2 The end of one side of the anesthesia mask 3 can be provided with a folding part 33 which can be folded in multiple sections, and the folding part 33 is configured to be folded upward to form an arc-shaped opening 32. The anesthesia mask 3 is also provided with a traction rope 34, which is configured to pull the folding part 33 upward or downward to adjust the size of the arc-shaped opening 32 for the head and neck of the experimental mouse to pass through. Specifically, the folding part 33 has left and right parts, and the traction rope 34 has two parts, respectively used to pull the left and right parts of the folding part 33. It should be noted that the principle of pulling the folding part 33 by the traction rope 34 is the same as that of the folding of the shutter, which will not be described here. The folding part 33 can be folded multiple times to form arc-shaped openings 32 of different sizes for the head and neck of experimental mice of different sizes to pass through, so as to meet the different experimental mice and the arc-shaped opening 32 of the anesthesia mask 3 without large gaps.

[0036] Further, referring to Figure 2 The anesthesia mask 3 can be provided with a ventilation hole 35, and the ventilation hole 35 is provided with a cover. If the concentration of anesthetic gas in the anesthesia mask 3 is too high, the cover can be quickly opened to allow air to flow in from the ventilation hole 35 to ensure the safety of the experimental mouse.

[0037] In some embodiments, referring to Figure 2 The anesthesia mask 3 is provided with a through hole, and the through hole is provided with a breathing part 36, and the breathing part 36 is formed with a breathing hole. The breathing part 36 is also provided with an adjusting valve, and the amount of air entering the anesthesia mask 3 can be controlled by the valve.

[0038] In some embodiments, referring to Figure 2 The anesthesia mask 3 is connected with an anesthesia bottle through a first connecting pipe 37, and the first connecting pipe 37 is also connected with a first flow adjusting valve 38 to adjust the speed of anesthetic gas entering the anesthesia mask 3.

[0039] Before X-ray photography of experimental mice or other operations with shorter time, the animal needs to be induced by gas anesthesia. The animal gas anesthesia machine commonly used in the laboratory is large in size, inconvenient to carry, and the anesthesia induction device and anesthesia maintenance device cannot be used independently, which cannot meet the needs of segmented operation. In the related art, the way of manually grabbing and fixing the size of the mouse is mainly used, and the head is buried in the anesthesia bottle. This operation cannot accurately adjust the inhaled flow of anesthetic gas, which can easily lead to the death of animals due to anesthesia, and consumes time and manpower.

[0040] Therefore, according to a second aspect of the present disclosure, as shown in Figure 1 、 Figure 3 An X-ray radiography anesthesia system is also provided, which can include the anesthesia induction device 6 and the anesthesia maintenance and fixing device described above. The anesthesia induction device 6 is configured as a transparent box, and two second connecting pipes 7 are provided on the transparent box. One of the second connecting pipes 7 is used to communicate with the anesthesia bottle 8, and the other is used to communicate with the atmosphere. Through the above arrangement, the anesthesia induction device 6 is small in size and can be separated from the anesthesia maintenance and fixing device, which is convenient for independent carrying and carrying. The flow of anesthetic gas and air into the anesthesia induction device 6 is adjusted by the second flow regulating valve 9 on the second connecting pipe 7, which is convenient for independent use and has the advantages of time saving, rapidity and convenience. The anesthesia induction device 6 is a transparent box, which is convenient for observing the state of the animal. The lid is provided with a carrying rod 61, which is convenient for carrying and transporting. In the embodiment of the present disclosure, the length of the anesthesia induction device 6 is 40-42 cm, specifically 41 cm, the width is 25-30 cm, specifically 28 cm, and the height is 20-25 cm, specifically 23 cm. 5-8 rats can be induced into an anesthetic state at the same time, without the need for manual grabbing of animals, saving time and effort. The experimental mouse X-ray radiography anesthesia system has all the beneficial effects of the anesthesia maintenance and fixing device described above, which will not be repeated here.

[0041] The use process of the X-ray anesthesia system is as follows: 1. Anesthesia induction: 5-8 rats are placed into the anesthesia induction device 6 at one time, the isoflurane concentration in the anesthesia induction device 6 is maintained at 3%-4% through the second flow regulating valve 9, and the experimental mouse breathes deeply and slowly, the body is soft and there is no obvious struggle, which indicates that the anesthesia induction is successful. 2. Anesthesia maintenance: the experimental mouse is transferred to the fixing plate 1 of the anesthesia maintenance and fixing device, the head and neck are inserted into the anesthesia mask 3, the large diameter of the arc-shaped opening 32 is adjusted to be about 0.5 cm apart from the experimental mouse neck; the breathing hole of the anesthesia mask 3 and the first flow regulating valve 38 are opened, and the isoflurane flow is maintained at 0.4 L / min-0.6 L / min, if the experimental mouse is observed to have respiratory depression, the first flow regulating valve 38 should be closed immediately, and the amount of air entering the anesthesia mask 3 is increased at the breathing part 36, and the experimental mouse breathes deeply and slowly, the body is soft and there is no obvious struggle, which indicates that the anesthesia maintenance is successful. 3. Experimental mouse double lower limb lateral film shooting: the experimental mouse is in a supine position, two elastic ropes 21 are used to fix the ankle parts of the experimental mouse double lower limbs respectively, so that the double lower limbs are 45° outwardly extended, and the double lower limb lateral film shooting is performed. 4. Experimental mouse double lower limb anteroposterior film shooting: the experimental mouse is in a supine position, two elastic ropes 21 are used to fix the ankle parts of the experimental mouse double lower limbs respectively, so that the double lower limbs are straight downward, the toes are upward and slightly inwardly rotated, and the double lower limb anteroposterior film shooting is performed. 5. Experimental mouse removal and state observation: after the double lower limb anteroposterior and lateral X-ray film shooting is completed, the fixing is released, the size of the arc-shaped opening 32 is increased, the head of the experimental mouse is away from the anesthesia mask 3, and the state of the experimental mouse is observed after the experimental mouse is returned to the cage, and the respiratory rate is gradually accelerated, and the experimental mouse tail has a response to stimulation, which indicates that the vital signs of the experimental mouse are good.

[0042] The preferred embodiments of the present disclosure are described in detail above with reference to the drawings, but the present disclosure is not limited to the specific details in the above-described embodiments, and various simple modifications can be made to the technical solutions of the present disclosure within the technical concept of the present disclosure, and these simple modifications all belong to the protection scope of the present disclosure.

[0043] In addition, it should be noted that various specific technical features described in the above specific embodiments can be combined in any appropriate manner without contradiction, and in order to avoid unnecessary repetition, various possible combination manners are not described again in the present disclosure.

[0044] In addition, various different embodiments of the present disclosure can also be combined in any appropriate manner, as long as they do not deviate from the idea of the present disclosure, and they should also be considered as disclosed by the present disclosure.

Claims

1. An anesthesia maintenance, immobilization device, characterized in that, include: A fixed plate, wherein first sliding grooves extending in the front-to-back direction are respectively formed at the left and right ends of the fixed plate, and second sliding grooves extending in the left-to-right direction are respectively formed at the front and rear ends of the fixed plate; A plurality of fixing rods, slidably mounted on the first sliding groove and the second sliding groove, respectively, for fixing the limbs of the experimental mouse; as well as An anesthesia mask is mounted on the middle portion of the front end of the fixing plate.

2. The anesthesia maintenance, immobilization device of claim 1, wherein, Two first sliding grooves arranged at intervals are formed at the left and right ends of the fixing plate, and two second sliding grooves arranged at intervals are formed at the front and rear ends of the fixing plate. The anesthesia mask is installed between the two second sliding grooves located at the front end of the fixing plate.

3. The anesthesia maintenance, immobilization device of claim 1, wherein, An elastic rope is installed on each of the fixing rods, and one end of the elastic rope away from the fixing rod is used to fix the limbs of the experimental mouse.

4. The anesthesia maintenance, immobilization device of claim 1, wherein, Grid lines are drawn on the fixing plate.

5. The anesthesia maintenance, immobilization device of claim 1, wherein, A scale is mounted on the fixing plate along the left-right direction and / or the front-back direction.

6. The anesthesia maintenance, immobilization device of claim 5, wherein, The scale of the scale ruler is formed with dot-shaped protrusions.

7. The anesthesia maintenance, immobilization device of claim 1, wherein, A plurality of fixing straps are connected to the anesthesia mask, and the fixing straps are sleeved on the fixing plate.

8. The anesthesia maintenance, immobilization device of claim 1, wherein, The end of one side of the anesthesia mask is provided with a folding portion that can be folded in multiple sections. The folding portion is configured to fold upward to form an arc-shaped opening. A traction rope is also installed on the anesthesia mask. The traction rope is configured to pull the folding portion to fold upward or downward to adjust the size of the arc-shaped opening for the head and neck of the experimental mouse to pass through.

9. The anesthesia maintenance, immobilization device of claim 1, wherein, A vent hole is provided on the anesthesia mask, and a cover body is provided on the vent hole.

10. An x-ray radiography system, characterized in that, It comprises an anesthesia induction device and an anesthesia maintenance and fixation device according to any one of claims 1 to 9, wherein the anesthesia induction device is constructed as a transparent box, and two second connecting tubes are provided on the transparent box, one of which is used to connect to the anesthesia bottle, and the other is used to connect to the atmosphere.