Device for inoculating tumor cells to mice

Abstract

The utility model relates to the field of biomedicine and experimental animal research, in particular to a device for inoculating tumor cells to a mouse. The utility model aims to provide a device for inoculating tumor cells to a mouse, which can be used for conveniently turning over the fixed mouse when the tumor cells are inoculated to the mouse, so that an operator can observe an inoculation part at any angle and carry out accurate inoculation work. According to the technical scheme, the device for inoculating the tumor cells to the mice comprises a supporting frame and square frames fixedly connected to the left side and the right side of the supporting frame, and the periphery of each square frame is rotationally connected with a limiting wheel. And the multiple limiting wheels on the two sides are each rotationally connected with a circular frame in a lap joint mode, a rectangular frame is fixedly connected between the two circular frames, the front side and the rear side of the rectangular frame are each slidably connected with an embedded base, and a strip-shaped frame is fixedly connected between the two embedded bases.

Description

Technical Field

[0001] This invention relates to the fields of biomedicine and laboratory animal research, and more specifically to a device for inoculating mice with tumor cells. Background Technology

[0002] In mouse tumor research, accurately and efficiently inoculating tumor cells into mice is a crucial step. However, traditional manual inoculation methods suffer from problems such as complex operation, poor accuracy, and stress on animals. Therefore, a novel device is needed to improve the accuracy and efficiency of inoculation while reducing the impact on experimental animals. Existing technologies, such as the mouse tumor inoculation fixation device described in application number 202121662955.5, involve multiple operators, resulting in high labor costs and the risk of lab technicians being bitten by mice, as well as significant mouse stress. This device is unsuitable for inoculating mice with tumor cells. A more efficient method would involve rotating the fixed mouse, allowing the operator to observe the inoculation site from any angle and perform precise inoculation. Utility Model Content

[0003] The purpose of this invention is to provide a device for inoculating mice with tumor cells. When inoculating mice with tumor cells, it is convenient to rotate the fixed mice so that the operator can observe the inoculation site from any angle and perform precise inoculation.

[0004] The purpose of this utility model is achieved through the following technical solution: a device for inoculating tumor cells into mice, comprising a support frame and square frames fixedly connected to the left and right sides of the support frame, a limiting wheel rotatably connected to the four sides of each square frame, a circular frame rotatably connected to the multiple limiting wheels on both sides, a rectangular frame fixedly connected between two circular frames, an insert seat slidably connected to the front and rear sides of the rectangular frame, and a strip frame fixedly connected between two insert seats.

[0005] Each of the limiting wheels has a thin wall on both sides, and the thin walls on both sides are in contact with the two sides of the corresponding circular frame.

[0006] The strip frame has a rectangular through hole on both the top and bottom sides.

[0007] The two square frames are set in a mirror image.

[0008] A right-angle frame is fixedly connected to the right side of the rectangular frame, and a handle is fixedly connected to the right side of the right-angle frame. Attached Figure Description

[0009] The present invention will now be described in further detail with reference to the accompanying drawings and specific implementation methods.

[0010] Figure 1This is a partial structural schematic diagram of the support frame of this utility model;

[0011] Figure 2 This is a utility model Figure 1 A magnified schematic diagram of a local structure;

[0012] Figure 3 This is a partial structural diagram of the rectangular frame of this utility model;

[0013] Figure 4 This is a partial structural schematic diagram of the sliding seat of this utility model;

[0014] Figure 5 This is a partial structural schematic diagram of the clamping base of this utility model;

[0015] Figure 6 This is a partial structural schematic diagram of the bar frame of this utility model;

[0016] Figure 7 and 8 These are all schematic diagrams of the overall structure of this utility model.

[0017] In the figure: support frame 101; square frame 102; limiting wheel 103; rectangular frame 201; positioning hole 202; circular frame 203; right-angle frame 204; sliding seat 301; clamping seat 302; spring 303; pin 304; strip frame 401; embedding seat 402. Detailed Implementation

[0018] A device for inoculating mice with tumor cells includes a support frame 101 and square frames 102 fixedly connected to the left and right sides of the support frame 101. Each square frame 102 is rotatably connected to a limiting wheel 103 around its perimeter. A circular frame 203 is rotatably attached to each of the multiple limiting wheels 103 on both sides. A rectangular frame 201 is fixedly connected between two circular frames 203. An insert seat 402 is slidably connected to the front and rear sides of the rectangular frame 201. A strip frame 401 is fixedly connected between two insert seats 402.

[0019] This section is based on Figure 1-8The working process described is as follows: When inoculating mice with tumor cells, to facilitate the rotation of the fixed mice so that the operator can observe the inoculation site at any angle and perform precise inoculation, preventing deviation in the inoculation position, the anesthetized mouse is placed through the strip frame 401, and the inoculation site is aligned with the center of the strip frame 401. The strip frame 401, along with the two insert seats 402, is pre-adjusted laterally on the rectangular frame 201. Then, when it is necessary to rotate the mouse and determine the inoculation position, the... The rectangular frame 201 is manually pushed and rotated along its central axis by two circular frames 203. To make the rotation limit more stable, the outer sides of the two circular frames 203 are respectively attached to the inner surfaces of the limit wheels 103 on both sides. The rotation of multiple limit wheels 103 provides rotation limit for the circular frames 203 on both sides, making the rotation of the circular frames 203 more stable. When inoculating mice with tumor cells, it is convenient to turn the fixed mice over so that the operator can observe the inoculation site at any angle and perform precise inoculation.

[0020] Each of the limiting wheels 103 has a thin wall on both sides, and the thin walls on both sides are in contact with the two sides of the corresponding circular frame 203.

[0021] This section is based on Figure 1-8 The working process described is as follows: each of the limiting wheels 103 has a thin wall on both sides, and the thin wall on both sides contacts the two sides of the corresponding circular frame 203, so that the circular frame 203 can be locked and limited by the thin wall protruding on both sides of each limiting wheel 103, preventing the circular frame 203 from falling off when rotating.

[0022] The strip frame 401 has a rectangular through hole on both the top and bottom sides.

[0023] This section is based on Figure 1-8 The process described is as follows: when inoculating mice, the inoculation area is aligned with the rectangular through-hole to improve the accuracy of the inoculation.

[0024] The two square frames 102 are set in a mirror image.

[0025] A right-angle frame 204 is fixedly connected to the right side of the rectangular frame 201, and a handle is fixedly connected to the right side of the right-angle frame 204.

[0026] This section is based on Figure 1-8 The working process described is as follows: when the rectangular frame 201 is rotated by the two circular frames 203, the person grabs the handle located on the right side of the right-angle frame 204, and after rotating the right-angle frame 204, the rectangular frame 201 is rotated by the two circular frames 203.

[0027] At each of the four corners of the rectangular frame 201, a sliding seat 301 is slidably connected, and a clamping seat 302 is slidably connected to each sliding seat 301. The adjacent side of each clamping seat 302 is semi-circular.

[0028] Two springs 303 are respectively sleeved on the outer side of each clamping seat 302, and the two sides of the two springs 303 are respectively fixedly connected to the corresponding sliding seat 301 and the corresponding clamping seat 302.

[0029] Each of the springs 303 is a compression spring.

[0030] This section is based on Figure 1-8 The working process described is as follows: To facilitate the fixation of the mouse's limbs and prevent the anesthetic strength from decreasing during inoculation and causing the mouse to struggle, during use, each clamping seat 302 slides towards the inside of the rectangular frame 201, causing each spring 303 to compress. Then, the mouse's limbs are clamped between the clamping seat 302 and the sliding seat 301 through the semi-circular position on one side of each clamping seat 302. The compression elasticity of each spring 303 provides clamping force for the above clamping movement, which facilitates the fixation of the mouse's limbs while preventing the anesthetic strength from decreasing during inoculation and causing the mouse to struggle. Furthermore, the spacing between each sliding seat 301 can be adjusted according to the lateral movement of each sliding seat 301, making it suitable for clamping and limiting mice of different lengths.

[0031] The rectangular frame 201 is provided with multiple positioning holes 202 evenly on its front and rear sides.

[0032] Each of the sliding seats 301 has a pin 304 inserted into it. The pin 304 on each sliding seat 301 is fixed and limited by being inserted into any of the positioning holes 202.

[0033] This section is based on Figure 1-8 The working process described is as follows: After adjusting the lateral position of each sliding seat 301, in order to facilitate the fixation and limitation of each sliding seat 301 and prevent the sliding seat 301 from moving again after the mouse is fixed, during use, after moving each sliding seat 301, the sliding seat 301 is moved to the corresponding positioning hole 202. Then, the pin 304 is inserted into the sliding seat 301 and passes through the positioning hole 202 to limit the sliding seat 301 and prevent the sliding seat 301 from moving again after the mouse is fixed.

Claims

1. A device for inoculating mice with tumor cells, comprising a support frame (101) and square frames (102) fixedly connected to the left and right sides of the support frame (101), characterized in that: Each of the square frames (102) is rotatably connected to a limiting wheel (103) around its perimeter. A circular frame (203) is rotatably attached to each of the multiple limiting wheels (103) on both sides. A rectangular frame (201) is fixedly connected between two circular frames (203). An embedded seat (402) is slidably connected to the front and rear sides of the rectangular frame (201). A strip frame (401) is fixedly connected between two embedded seats (402).

2. The device for inoculating tumor cells into mice according to claim 1, characterized in that: Each of the limiting wheels (103) has a thin wall on both sides, and the thin walls on both sides are in contact with the two sides of the corresponding circular frame (203).

3. The device for inoculating tumor cells into mice according to claim 1, characterized in that: The strip frame (401) has a rectangular through hole on both the top and bottom sides.

4. The device for inoculating tumor cells into mice according to claim 1, characterized in that: The two square frames (102) are set in a mirror image.

5. The device for inoculating tumor cells into mice according to claim 1, characterized in that: A right-angle frame (204) is fixedly connected to the right side of the rectangular frame (201), and a handle is fixedly connected to the right side of the right-angle frame (204).

6. The device for inoculating tumor cells into mice according to claim 1, characterized in that: At each of the four corners of the rectangular frame (201), a sliding seat (301) is slidably connected, and a clamping seat (302) is slidably connected on each sliding seat (301). The adjacent side of each clamping seat (302) is semi-circular.

7. The device for inoculating tumor cells into mice according to claim 6, characterized in that: Two springs (303) are respectively sleeved on the outer side of each clamping seat (302), and the two sides of the two springs (303) are respectively fixedly connected to the corresponding sliding seat (301) and the corresponding clamping seat (302).

8. The device for inoculating tumor cells into mice according to claim 7, characterized in that: Each of the springs (303) is a compression spring.

9. The device for inoculating tumor cells into mice according to claim 8, characterized in that: The rectangular frame (201) is provided with multiple positioning holes (202) evenly on its front and rear sides.

10. The device for inoculating tumor cells into mice according to claim 9, characterized in that: Each of the sliding seats (301) has a pin (304) inserted into it. The pin (304) on each sliding seat (301) is fixed and limited by being inserted into any of the positioning holes (202).

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