Fixing device for fetal monkey tissue slice

Abstract

The utility model discloses a fixing device for fetal monkey tissue slices, which comprises a mounting base, a bearing coaming is mounted on the surface of the mounting base to form a fence to avoid leakage during agar injection, a mounting rack is arranged on the upper side of the bearing coaming, and a needle bar is slidably connected to the inner side of the mounting rack; an agar inlet is formed in the rear side of the bearing coaming, and a hole-shaped structure is formed in the upper end of the bearing coaming; limiting columns corresponding to the hole-shaped structures at the upper ends of the bearing surrounding plates are fixed to the lower ends of the mounting frames, and the limiting columns and the bearing surrounding plates are connected in a clamped mode. The fetal monkey tissue recarving device has the following beneficial effects that a three-dimensional needle structure formed by the mounting frame and the needle rod is used for recarving the surface of the fetal monkey tissue, so that the growth change of the fetal monkey tissue can be conveniently observed in the later period; the height difference is formed between the needle rod which is not influenced by the gravity of the fetal monkey tissue on the periphery and the glided needle rod, so that a positioning structure is formed for the fetal monkey tissue, and later slicing is facilitated.

Description

Technical Field

[0001] This application relates to the field of fetal monkey tissue sectioning technology, specifically to a fixation device for fetal monkey tissue sectioning. Background Technology

[0002] Non-human primates (laboratory monkeys) possess brain structures and functions highly similar to humans, and their neural development processes are also very similar to those of humans. Therefore, culturing fetal brain tissue from primates (laboratory monkeys) is of great significance for scientific research.

[0003] Existing technology discloses a tumor tissue slicing device, belonging to the field of medical technology, which solves the technical problem of uneven texture of tumors during slicing. This tumor tissue slicing device can cut more uniform slices, making it easier to select and observe the best-performing slices, resulting in better performance.

[0004] During the experiment, the fixation method for fetal monkey brain tissue is different from that for conventional tissue sections due to the softness of the brain tissue itself. Care must be taken to avoid damaging the brain tissue. Furthermore, uneven slice thickness is prone to occur when slicing the whole tissue, and the ability to replicate the shape of the fetal monkey tissue is relatively low. Utility Model Content

[0005] Therefore, this application provides a fixation device for fetal monkey tissue slicing to solve the problems of uneven slice thickness and low replication ability of fetal monkey tissue shape when performing whole slicing in the prior art.

[0006] To achieve the above objectives, this application provides the following technical solution:

[0007] A fixation device for fetal monkey tissue sections includes:

[0008] The mounting base has a bearing plate installed on its surface to form a fence to prevent leakage during agar injection. The upper side of the bearing plate is provided with a mounting frame, and the inner side of the mounting frame is slidably connected to a needle rod.

[0009] An agar inlet is installed on the rear side of the load-bearing enclosure.

[0010] Optionally, the upper end of the supporting enclosure is provided with a perforated structure.

[0011] Optionally, the lower end of the mounting bracket is fixed with a limiting post corresponding to the hole-like structure at the upper end of the bearing enclosure, and the limiting post and the bearing enclosure are engaged.

[0012] Optionally, a mounting ear plate is also installed on the outer side of the mounting bracket, and a perforated structure is installed on the inner side of the mounting ear plate.

[0013] Optionally, the upper end of the mounting base is also equipped with a limiting rod corresponding to the mounting ear plate, and the limiting rod is installed through the mounting ear plate.

[0014] Optionally, a limiting bolt is also threaded onto the outer side of the limiting rod.

[0015] Optionally, a cover plate is also provided on the upper side of the mounting bracket, and the horizontal height of the inner surface of the cover plate is the same as the horizontal height of the upper end face of the needle bar.

[0016] Optionally, a rubber sleeve is also installed at the connection between the needle bar and the mounting bracket.

[0017] Optionally, the rubber sleeve is engaged with the mounting frame, and the rubber sleeve is fitted to the needle bar and the mounting frame.

[0018] Compared with the prior art, this application has at least the following beneficial effects:

[0019] 1. The three-dimensional needle structure consisting of the mounting frame and needle bar replicates the surface of the fetal monkey tissue, facilitating later observation of the growth and changes of the fetal monkey tissue.

[0020] 2. By utilizing the height difference between the needle bar that is not affected by the gravity of the fetal monkey tissue and the needle bar that has already slid down, a positioning structure is formed for the fetal monkey tissue, which facilitates subsequent sectioning. Attached Figure Description

[0021] To more intuitively illustrate the prior art and this application, exemplary drawings are provided below. It should be understood that the specific shapes and structures shown in the drawings should not generally be regarded as limiting conditions for implementing this application; for example, based on the technical concept disclosed in this application and the exemplary drawings, those skilled in the art are capable of making conventional adjustments or further optimizations to the addition / reduction / classification of certain units, their specific shapes, positional relationships, connection methods, size ratios, etc.

[0022] Figure 1 This is a frontal cross-sectional view of a fixation device for fetal monkey tissue sectioning provided in one embodiment of this application;

[0023] Figure 2 This is a bottom view of a fixation device for fetal monkey tissue sectioning in one embodiment of this application;

[0024] Figure 3 For this application Figure 1 Enlarged structural diagram at point A in the middle.

[0025] Explanation of reference numerals in the attached figures:

[0026] 1. Mounting base; 2. Bearing plate; 3. Mounting bracket; 4. Needle bar; 5. Cover plate; 6. Limiting rod; 7. Mounting ear plate; 8. Limiting bolt; 9. Limiting post; 10. Agar inlet; 11. Rubber sleeve. Detailed Implementation

[0027] The present application will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0028] This utility model provides a fixing device for fetal monkey tissue slicing, including a mounting base 1. A bearing plate 2 is installed on the surface of the mounting base 1 to form a fence to prevent leakage during agar injection. A mounting frame 3 is provided on the upper side of the bearing plate 2, and a needle bar 4 is slidably connected to the inner side of the mounting frame 3. It adopts a three-dimensional needle structure. The needle bar 4 is slid down by the weight of the fetal monkey tissue itself. The needle bar 4 that is not affected by the weight of the fetal monkey tissue cannot slide down and surrounds the needle bar 4, thereby forming a depression with the same shape as the fetal monkey tissue. The height difference between the needle bar 4 that is not affected by the weight of the fetal monkey tissue and the needle bar 4 that has slid down is used to position the fetal monkey tissue.

[0029] An agar inlet 10 is installed on the rear side of the supporting plate 2 for injecting agar, supporting the lower end of the slid-down needle bar 4 and blocking the agar formation. This ensures that when the agar is set, the internal pits and depressions are the same as the fetal monkey tissue placed at the upper end of the needle bar 4, which facilitates subsequent molding. After the needle bar 4 is limited by the agar, it can no longer move, thus completely positioning the fetal monkey tissue and facilitating subsequent sectioning.

[0030] The upper end of the bearing enclosure 2 is provided with a hole-like structure, and the lower end of the mounting frame 3 is fixed with a limiting post 9 corresponding to the hole-like structure at the upper end of the bearing enclosure 2. The limiting post 9 and the bearing enclosure 2 form a snap-fit ​​connection, so that the mounting frame 3 can be positioned with the bearing enclosure 2 to prevent random movement.

[0031] Mounting bracket 3 is also equipped with mounting ear plate 7 on the outside, and mounting ear plate 7 has a hole structure on the inside. Mounting base 1 is also equipped with a limiting rod 6 corresponding to mounting ear plate 7 at the upper end. The limiting rod 6 is installed through the mounting ear plate 7. The limiting rod 6 is also threaded with a limiting bolt 8 on the outside of the limiting rod 6 to position the mounting ear plate 7.

[0032] Specifically, after the limit bolts 8 are fixed, they work with the bearing plate 2 to form positioning on the upper and lower sides, preventing random movement and making it easier to remove the mounting bracket 3 later to take out the agar inside the bearing plate 2.

[0033] A cover plate 5 is also provided on the upper side of the mounting bracket 3. The horizontal height of the inner surface of the cover plate 5 is the same as the horizontal height of the upper end of the needle bar 4. This allows the cover plate 5 to increase a certain degree of pressure on the fetal monkey tissue after it is placed, so that the fetal monkey tissue can make contact with the needle bar 4 as much as possible, ensuring the complete replication of the shape of the fetal monkey tissue.

[0034] A rubber sleeve 11 is also installed at the connection between the needle bar 4 and the mounting frame 3. The rubber sleeve 11 and the mounting frame 3 form a snap-fit ​​connection, and the rubber sleeve 11 is fitted to the needle bar 4 and the mounting frame 3 to prevent the agar injected inside the bearing plate 2 from overflowing upwards to the upper surface of the mounting frame 3.

[0035] The technical features of the above embodiments can be combined in any way as long as there is no contradiction in the combination of these technical features. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described; these embodiments not explicitly written should also be considered to be within the scope of this specification.

Claims

1. A fixation device for fetal monkey tissue sections, characterized in that, include: Mounting base (1), the surface of which is mounted with a bearing enclosure (2) to form a fence to prevent leakage during agar injection, and a mounting frame (3) is provided on the upper side of the bearing enclosure (2), and a needle rod (4) is slidably connected to the inner side of the mounting frame (3). An agar inlet (10) is installed on the rear side of the bearing enclosure (2).

2. The fixation device for fetal monkey tissue sections according to claim 1, characterized in that, The upper end of the bearing enclosure (2) has a perforated structure.

3. The fixation device for fetal monkey tissue sections according to claim 2, characterized in that, The lower end of the mounting bracket (3) is fixed with a limiting post (9) corresponding to the hole structure at the upper end of the bearing enclosure (2), and the limiting post (9) and the bearing enclosure (2) are engaged.

4. The fixation device for fetal monkey tissue sectioning according to claim 1, characterized in that, The mounting bracket (3) is also equipped with a mounting ear plate (7) on its outer side, and the mounting ear plate (7) is equipped with a perforated structure on its inner side.

5. The fixation device for fetal monkey tissue sections according to claim 4, characterized in that, The upper end of the mounting base (1) is also equipped with a limiting rod (6) corresponding to the mounting ear plate (7), and the limiting rod (6) is installed through the mounting ear plate (7).

6. The fixation device for fetal monkey tissue sections according to claim 5, characterized in that, The limiting rod (6) is also threaded with a limiting bolt (8) on its outer side.

7. The fixation device for fetal monkey tissue sections according to claim 1, characterized in that, The mounting bracket (3) is also provided with a cover plate (5) on its upper side. The inner surface of the cover plate (5) is at the same horizontal height as the upper end face of the needle bar (4).

8. The fixation device for fetal monkey tissue sections according to claim 1, characterized in that, A rubber sleeve (11) is also installed at the connection between the needle bar (4) and the mounting bracket (3).

9. A fixation device for fetal monkey tissue sections according to claim 8, characterized in that, The rubber sleeve (11) and the mounting bracket (3) are engaged, and the rubber sleeve (11) is fitted to the needle bar (4) and the mounting bracket (3).

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