Gradient aperture stent for segmental bone defect

By designing a gradient pore size scaffold for segmental bone defects, the problems of difficult new bone ingrowth and insufficient vascularization of traditional scaffolds are solved, enabling effective osteoblast ingrowth and stable growth of new tissue, and providing shaping and connection fixation functions for biomimetic bone tissue.

CN223555016UActive Publication Date: 2025-11-18FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202422762736.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-13
Publication Date
2025-11-18
Estimated Expiration
2034-11-13

AI Technical Summary

Technical Problem

Traditional bone repair scaffolds have limitations in segmental bone defects due to difficulties in new bone ingrowth, insufficient material degradation, and inadequate vascularization of the scaffold, which restrict their widespread application.

Method used

A gradient aperture scaffold for segmental bone defects was designed, comprising a first sphere and a second sphere, the inner and outer spheres being connected to an inner cavity through a through hole, the inner skeleton being randomly distributed, and combined with a shaping tube, a reinforcing rod and a connecting sleeve, providing shaping, reinforcement and connection functions to assist in the growth of new tissue.

Benefits of technology

This scaffold facilitates osteoblast ingrowth and angiogenesis infiltration, mimicking the structure of human bone tissue to promote new tissue growth. It also provides an optimized cell growth environment through shaping and connection structures to achieve stable fixation.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223555016U_ABST
    Figure CN223555016U_ABST
Patent Text Reader

Abstract

The utility model discloses a gradient aperture stent for segmental bone defect, and particularly relates to the technical field of bone repair, the gradient aperture stent comprises a first ball body and a second ball body, the second ball body is fixed on the outer side of the first ball body, and auxiliary components for new tissue growth are arranged in the first ball body and the second ball body. Through the arrangement of the first inner cavity and the second inner cavity, the inside and the outside of the first ball body and the inside and the outside of the second ball body are communicated with each other under the assistance of the first through hole and the second through hole, and the first framework, the second framework, the third framework and the fourth framework in the first inner cavity and the second inner cavity are mutually combined and distributed disorderly, so that the internal osteogenesis space is favorably released; according to the invention, the structure is more beneficial to the growth of osteoblasts and the inward infiltration of vascular cells, the disordered structure is also beneficial to the crawling growth of osteoblasts on the surface of the stent, and meanwhile, the whole trabecular bone structure also simulates the structure of human bone tissues and assists the growth of tissues, so that the auxiliary function of the growth of new tissues when the stent is used is realized.
Need to check novelty before this filing date? Find Prior Art

Description

TECHNICAL FIELD

[0001] The utility model relates to bone repair technical field especially is related to a gradient aperture support for segmental bone defect. BACKGROUND

[0002] Bone defect repair is a thorny problem in clinic, and in recent years, bone defect caused by serious trauma, infection and tumor etc. presents the characteristics of high incidence and high disability rate;

[0003] With the rapid development of bone tissue engineering technology in recent years, bone tissue engineering scaffold implantation in bone defect area to treat bone defect becomes the current treatment new means, and the innovative design of bone regeneration scaffold occupies the dominant position. Although the traditional scaffold material can provide certain mechanical support and structure support for specific cells and guide new tissue growth after filling the defect site, there are still some problems such as difficulty in new bone growth, insufficient material degradation and insufficient vascularization in the center of the scaffold, which restrict its wide application.

[0004] Therefore, a gradient aperture support for segmental bone defect is needed to solve the above problems. UTILITY MODEL CONTENTS

[0005] The utility model aims at providing a gradient aperture support for segmental bone defect to solve the problem of inconvenient new tissue growth in the use of the support in the background art.

[0006] The utility model relates to a gradient aperture support for segmental bone defect, which comprises a first sphere and a second sphere, the outer side of the first sphere is fixed with the second sphere, the inside of the first sphere and the second sphere is provided with an auxiliary assembly for new tissue growth, the auxiliary assembly comprises a first through hole, a first inner cavity, a first positioning block, a first skeleton, a second skeleton, a second through hole, a second inner cavity, a second positioning block, a third skeleton and a fourth skeleton, the outer side wall of the first sphere is provided with the first through hole, the inside of the first sphere is provided with the first inner cavity, the inside of the first inner cavity is provided with the first positioning block, the outer side wall of the first positioning block is fixed with the first skeleton, the outer side wall of the first skeleton is fixed with the second skeleton, the outer side wall of the second sphere is fixed with the second through hole, the inside of the second sphere is provided with the second inner cavity, the inside of the second inner cavity is provided with the second positioning block, the outer side wall of the second positioning block is fixed with the third skeleton, and the outer side wall of the third skeleton is fixed with the fourth skeleton.

[0007] The utility model relates to a gradient aperture support for segmental bone defect, wherein the inner side wall of the first sphere is fixed with a shaped tube, the outer side wall of the shaped tube is fixed with a positioning table, the inside of the top end of the positioning table is provided with a first positioning groove, and the outside of the top end of the positioning table is provided with a second positioning groove.

[0008] The utility model discloses a gradient aperture support for segmental bone defect, wherein the positioning table is fixed with a plurality of positioning tables on the outer sidewall of the shaped tube.

[0009] The utility model discloses a gradient aperture support for segmental bone defect, wherein the outer sidewall of the shaped tube is provided with a through groove, and the inner sidewall of the shaped tube is fixed with a reinforcing rod.

[0010] The utility model discloses a gradient aperture support for segmental bone defect, wherein the through groove is provided with a plurality of through grooves on the outer sidewall of the shaped tube, and the plurality of through grooves are symmetrically distributed.

[0011] The utility model discloses a gradient aperture support for segmental bone defect, wherein the reinforcing rod is fixed with a plurality of reinforcing rods on the inner sidewall of the shaped tube, and the plurality of reinforcing rods are equidistantly distributed.

[0012] The utility model discloses a gradient aperture support for segmental bone defect, wherein the top end and the bottom end of the outer side of the second sphere are fixed with connecting sleeves, the bottom end of the connecting sleeve is fixed with a connecting piece, the inner sidewall of the connecting piece is provided with an antiskid groove, the bottom end of the outer sidewall of the connecting piece is provided with a fixing hole, the inside of the fixing hole is provided with a fixing bolt, the outer sidewall of the connecting piece is provided with a rope groove, and the inside of the rope groove is provided with a silk thread.

[0013] The utility model discloses a gradient aperture support for segmental bone defect, wherein the connecting piece is fixed with a plurality of connecting pieces at the bottom end of the connecting sleeve, and the plurality of connecting pieces are annularly distributed.

[0014] Compared with the prior art, the utility model has the beneficial effects that:

[0015] The gradient aperture support for segmental bone defect is provided with a first inner cavity and a second inner cavity, the first sphere and the second sphere are in communication under the assistance of the first through hole and the second through hole, the first skeleton and the second skeleton in the first inner cavity and the second inner cavity and the third skeleton and the fourth skeleton are combined with each other and are in disorderly distribution, which is beneficial to releasing the internal osteogenesis space, more conducive to the growth of osteoblasts and the infiltration of angioblasts, the disordered structure is also conducive to the growth of osteoblasts on the surface, and the whole trabecular bone structure also imitates the structure of human bone tissue, which is conducive to tissue growth and realizes the auxiliary function of new tissue growth when the support is used.

[0016] The utility model relates to a gradient aperture support for segmental bone defect through setting up the shaped tube, the shaped tube is located the inside of first sphere, the positioning platform of collocation outside, can position first sphere, second sphere position under the assistance of first positioning groove and second positioning groove, can assist first sphere, second sphere to carry out the shaping treatment as a whole, the surface multiple groups of through -groove, then assist inside and outside communication, the multiple groups of reinforcing rod of inside wall, then can assist to reinforce the treatment to the shaped tube, has realized the shaping reinforcement function when this support uses,

[0017] The utility model relates to a gradient aperture support for segmental bone defect through setting up the connecting sleeve and the connecting piece, the connecting sleeve is located the upper and lower end of first sphere, second sphere, when using, the connecting sleeve is covered in the fracture of bone with the connecting piece, silk thread can gather the connecting piece, fixed peg is used for fixing treatment, has realized the connecting fixed function of this support.

[0018] Below further illustrate the utility model's a gradient aperture support for segmental bone defect with the attached drawing. DRAWINGS

[0019] Figure 1 It is the front view cross -section structure schematic drawing of the utility model's a gradient aperture support for segmental bone defect,

[0020] Figure 2 It is the front view structure schematic drawing of the utility model's a gradient aperture support for segmental bone defect,

[0021] Figure 3 It is the front view cross -section structure schematic drawing of the utility model's a first sphere and second sphere in the gradient aperture support for segmental bone defect,

[0022] Figure 4 It is the front view cross -section structure schematic drawing of the utility model's a shaped tube in the gradient aperture support for segmental bone defect,

[0023] Figure 5 It is the front view cross -section structure schematic drawing of the utility model's a connecting sleeve and connecting piece in the gradient aperture support for segmental bone defect,

[0024] Marked in the drawing as follows: 1-first sphere;2-second sphere;3-first through -hole;4-first inner chamber;5-first positioning block;6-first framework;7-second framework;8-second through -hole;9-second inner chamber;10-second positioning block;11-third framework;12-fourth framework;13-shaped tube;14-positioning platform;15-first positioning groove;16-second positioning groove;17-through -groove;18-reinforcing rod;19-connecting sleeve;20-connecting piece;21-anti -slip groove;22-fixing hole;23-fixed peg;24-rope groove;25-silk thread. DETAILED DESCRIPTION

[0025] The following embodiments are used to illustrate the present application, but not to limit the scope of the present application.

[0026] Embodiment

[0027] Please refer to Figures 1-5 , the utility model provides an embodiment: a gradient aperture support for segmental bone defect, including first sphere 1 and second sphere 2, the outside of first sphere 1 is fixed with second sphere 2, the inside of first sphere 1, second sphere 2 is provided with the auxiliary assembly for new tissue growth, and the auxiliary assembly includes first through hole 3, first inner cavity 4, first locating block 5, first skeleton 6, second skeleton 7, second through hole 8, second inner cavity 9, second locating block 10, third skeleton 11 and fourth skeleton 12, the outside wall of first sphere 1 is provided with first through hole 3, the inside of first sphere 1 is provided with first inner cavity 4, the inside of first inner cavity 4 is provided with first locating block 5, the outside wall of first locating block 5 is fixed with first skeleton 6, the outside wall of first skeleton 6 is fixed with second skeleton 7, the outside wall of second sphere 2 is fixed with second through hole 8, the inside of second sphere 2 is provided with second inner cavity 9, the inside of second inner cavity 9 is provided with second locating block 10, the outside wall of second locating block 10 is fixed with third skeleton 11, and the outside wall of third skeleton 11 is fixed with fourth skeleton 12;

[0028] As Figure 1 , Figure 2 and Figure 3 As shown, in use, multiple groups of first sphere 1 and second sphere 2 are combined to form a double-layer tubular frame body, and meanwhile, multiple groups of first sphere 1 and second sphere 2 are in point contact with each other, so as to maximize the retention of extracellular matrix environment, and the spherical design can provide the maximum contact area of tissue fluid and stem cells in the tissue space, so as to provide optimal conditions for cell adhesion and proliferation and nutrient transport, and the first skeleton 6, the second skeleton 7, the third skeleton 11 and the fourth skeleton 12 in the first sphere 1 and the second sphere 2 are combined with each other in disordered distribution, which is beneficial to the release of internal osteogenesis space, and more conducive to the growth of osteoblasts and the infiltration of hemangioblasts, and the disordered structure is also conducive to the crawling growth of osteoblasts on the surface, and meanwhile, the whole trabecular bone structure also imitates the structure of human bone tissue, so as to assist tissue growth.

[0029] The inner side wall of the first sphere 1 is fixed with a shaping pipe 13, the outer side wall of the shaping pipe 13 is fixed with a positioning table 14, the positioning table 14 is fixed on the outer side wall of the shaping pipe 13 in several groups, the several positioning tables 14 are distributed in parallel, the inner side of the top end of the positioning table 14 is provided with a first positioning groove 15, the outer side of the top end of the positioning table 14 is provided with a second positioning groove 16, the outer side wall of the shaping pipe 13 is provided with a through groove 17, the through groove 17 is provided on the outer side wall of the shaping pipe 13 in several groups, the several through grooves 17 are distributed in symmetry, the inner side wall of the shaping pipe 13 is fixed with a reinforcing rod 18, the reinforcing rod 18 is fixed on the inner side wall of the shaping pipe 13 in several groups, the several reinforcing rods 18 are distributed at equal intervals;

[0030] As shown in Figure 1 and Figure 4 , in use, the shaping pipe 13 is located at the inner side of the first sphere 1, cooperates with the outer side first positioning groove 15 and the second positioning groove 16, can assist in auxiliary shaping and reinforcing treatment of the spherical frame body combined by the first sphere 1 and the second sphere 2, and the multiple groups of through grooves 17 on the surface of the shaping pipe 13 can assist in the flow of internal and external substances;

[0031] The top end and the bottom end of the outer side of the second sphere 2 are fixed with a connecting sleeve 19, the bottom end of the connecting sleeve 19 is fixed with a connecting piece 20, the connecting piece 20 is fixed on the bottom end of the connecting sleeve 19 in several groups, the several connecting pieces 20 are distributed in a ring shape, the inner side wall of the connecting piece 20 is provided with an anti-skid groove 21, the bottom end of the outer side wall of the connecting piece 20 is provided with a fixing hole 22, the inside of the fixing hole 22 is provided with a fixing bolt 23, the outer side wall of the connecting piece 20 is provided with a rope groove 24, and the inside of the rope groove 24 is provided with a silk thread 25;

[0032] As shown in Figure 1 , Figure 2 and Figure 5 , in use, the connecting sleeve 19 and the connecting piece 20 at the end position of the first sphere 1 and the second sphere 2 can be sleeved outside the broken bone, then the silk thread 25 can be wound at the rope groove 24 to assist in folding the multiple groups of connecting pieces 20, and then the fixing bolt 23 can be installed at the fixing hole 22 for further fixing operation.

[0033] Working principle: in use, a plurality of first ball 1 and second ball 2 combination into the outer double-layer pipe type ball rack structure, the second ball 2 combination into the spherical frame is located in the outer side of the first ball 1 combination into the spherical frame, the inner side of the first ball 1 is provided with a shaped tube 13, and the outer side positioning table 14 surface first positioning groove 15, second positioning groove 16 cooperation, can assist the first ball 1, second ball 2 combination into the spherical frame body for auxiliary shaping and reinforcement processing, a plurality of through slot 17 on the surface of the shaped tube 13 can assist the flow of internal and external material, in use, the connecting sleeve 19, connecting piece 20 of the first ball 1, second ball 2 end position can be sleeved on the outside of the broken bone, the first ball 1, second ball 2 is located between the broken bone, after placing, first in the rope groove 24 winding silk 25, assist a plurality of connecting piece 20 to gather, then, the fixed bolt 23 can be installed in the fixed hole 22, further fixed operation, complete installation and use, a plurality of first ball 1, second ball 2 between each other point contact, the maximum degree of preservation of extracellular matrix environment, spherical design can provide the maximum area of contact between tissue fluid and stem cells in the tissue space, provide the optimal conditions for cell adhesion proliferation, nutrition transport, under the assistance of the first through hole 3, second through hole 8, the first ball 1, second ball 2 realize internal and external communication, the first inner cavity 4, second inner cavity 9 inside the first skeleton 6, second skeleton 7 and third skeleton 11, fourth skeleton 12 combination, disorderly distributed, is beneficial to release the internal osteogenesis space, more conducive to osteoblasts and angioplasty cells into the infiltration, the structure of disorderly, also conducive to the osteoblasts on its surface crawling growth, while the whole trabecular bone structure also imitates the structure of human bone tissue, auxiliary tissue growth.

[0034] Although the utility model has been described in detail above with general description and specific embodiments, some modifications or improvements can be made on the basis of the utility model, which is obvious to those skilled in the art. Therefore, these modifications or improvements made on the basis of not deviating from the spirit of the utility model, all belong to the scope of the utility model claimed.

Claims

1. A gradient-pore scaffold for segmental bone defects, comprising a first sphere and a second sphere, characterized in that: The outer side of the first sphere is fixed with a second sphere, and the interiors of the first sphere and the second sphere are provided with an auxiliary assembly for new tissue growth; The auxiliary assembly comprises a first through hole, a first inner cavity, a first positioning block, a first framework, a second framework, a second through hole, a second inner cavity, a second positioning block, a third framework and a fourth framework, the outer side wall of the first sphere is provided with the first through hole, the interior of the first sphere is provided with the first inner cavity, the interior of the first inner cavity is provided with the first positioning block, the outer side wall of the first positioning block is fixed with the first framework, the outer side wall of the first framework is fixed with the second framework, the outer side wall of the second sphere is fixed with the second through hole, the interior of the second sphere is provided with the second inner cavity, the interior of the second inner cavity is provided with the second positioning block, the outer side wall of the second positioning block is fixed with the third framework, and the outer side wall of the third framework is fixed with the fourth framework.

2. The gradient-pore scaffold for segmental bone defect according to claim 1, wherein: The inner side wall of the first sphere is fixed with a shaping tube, the outer side wall of the shaping tube is fixed with a positioning table, the inner side of the top end of the positioning table is provided with a first positioning groove, and the outer side of the top end of the positioning table is provided with a second positioning groove.

3. The gradient-pore scaffold for segmental bone defect according to claim 2, wherein: The positioning table is fixed with a plurality of positioning tables on the outer side wall of the shaping tube, and the plurality of positioning tables are distributed in parallel.

4. The gradient-pore scaffold for segmental bone defect according to claim 2, wherein: The outer side wall of the shaping tube is provided with a through groove, and the inner side wall of the shaping tube is fixed with a reinforcing rod.

5. A gradient-pore scaffold for segmental bone defect according to claim 4, characterized in that: The through groove is provided with a plurality of through grooves on the outer side wall of the shaping tube, and the plurality of through grooves are distributed symmetrically.

6. The gradient-pore scaffold for segmental bone defect according to claim 4, wherein: The reinforcing rod is fixed with a plurality of reinforcing rods on the inner side wall of the shaping tube, and the plurality of reinforcing rods are distributed at equal intervals.

7. The gradient-pore scaffold for segmental bone defect according to claim 1, wherein: The top end and the bottom end of the outer side of the second sphere are fixed with connecting sleeves, the bottom end of the connecting sleeve is fixed with a connecting piece, the inner side wall of the connecting piece is provided with an anti-skid groove, the bottom end of the outer side wall of the connecting piece is provided with a fixing hole, the interior of the fixing hole is provided with a fixing bolt, the outer side wall of the connecting piece is provided with a rope groove, and the inner side of the rope groove is provided with a silk thread.

8. The gradient-pore scaffold for segmental bone defect according to claim 7, characterized in that: The connecting piece is fixed with a plurality of connecting pieces at the bottom end of the connecting sleeve, and the plurality of connecting pieces are distributed in a ring shape.