Novel pharmaceutical sterile filling device

Abstract

The utility model relates to the field of filling devices, in particular to a novel pharmaceutical sterile filling device which comprises a bearing plate, a collecting bottle, a supporting plate fixedly connected to the upper end of the bearing plate and a first bearing block fixedly connected to the upper end of the supporting plate. The first valve body and the infusion pump are opened, the infusion pump pumps liquid medicine in the sealing tank into the hollow box, the liquid medicine enters the guide cylinder along with gravity, the collecting assembly is opened to enable the collecting bottle to move upwards, the liquid outlet needle can penetrate through the sterile rubber plug to enter the collecting bottle for liquid injection, and when the interior of the hollow box needs to be emptied, the first valve body is closed; a third valve body and an air pump are opened, the air pump injects pressure gas into a hollow box, liquid in the hollow box can be emptied, a plurality of liquid outlet needles can rapidly fill a plurality of collecting bottles, and the problems that when an aseptic filling device in the prior art is used, the solution in a flow guide mechanism is difficult to rapidly emptied, and the filling efficiency is high are solved. And sterile filling is difficult to carry out on the whole row of bottle bodies.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the field of filling device, concretely relates to a novel pharmaceutical sterile filling device. BACKGROUND

[0002] With the rapid development of modern pharmaceutical industry, especially the production of high-end drugs such as biopharmaceuticals, vaccines and antibiotics, the sterile filling link in the pharmaceutical process plays a crucial role in ensuring the quality and safety of drugs. Sterile filling refers to the process of filling liquid drugs, injections or other preparations into containers under strict sterile conditions. This process directly affects the quality, effectiveness and safety of patients.

[0003] At present, the traditional sterile filling technology mainly includes laminar flow technology and negative pressure technology. By establishing a sterile local environment, it is ensured that the filling process is not contaminated by the outside world. However, the sterile filling device in the prior art has the problem that the solution in the flow guide mechanism is difficult to quickly empty, and the drug liquid adhering to the flow guide mechanism will cause inaccurate filling precision, and it is difficult to perform sterile filling on the whole row of bottles, which needs to be further improved.

[0004] Therefore, a novel pharmaceutical sterile filling device is proposed, which can quickly empty the solution in the flow guide mechanism, and the drug liquid will not adhere to the flow guide mechanism, thereby improving the filling precision and allowing sterile filling of the whole row of bottles. SUMMARY

[0005] In order to overcome the problem that the sterile filling device in the prior art is difficult to quickly empty the solution in the flow guide mechanism, the drug liquid adhering to the flow guide mechanism is easy to cause inaccurate filling precision, and it is difficult to perform sterile filling on the whole row of bottles, therefore, a novel pharmaceutical sterile filling device is proposed.

[0006] The technical scheme of the utility model is as follows: a novel pharmaceutical sterile filling device, comprising a bearing plate, a collection bottle, a support plate fixed to the upper end of the bearing plate, and a first bearing block fixed to the upper end of the support plate; a sealed tank and a liquid pumping pump are fixed to the upper end of the first bearing block, the liquid pumping end of the liquid pumping pump is connected to the liquid outlet end of the lower part of the side wall of the sealed tank, a flow guide assembly is arranged at the left end of the support plate, a gas pump is fixed to the side wall of the first bearing block, a collection assembly is arranged at the upper end of the bearing plate, a sterile rubber plug is fixed to the upper end of the collection bottle in a penetrating manner, one end of a first liquid outlet pipe is installed on the liquid outlet end of the liquid pumping pump, and one end of a connecting pipe is installed on the other end of the first liquid outlet pipe.

[0007] The diversion assembly comprises a hollow box, a first liquid inlet pipe, a first valve body, diversion cylinders, a second valve body, a liquid outlet needle, a fixing ring, an air inlet pipe and a third valve body; the left side of the support plate is provided with the hollow box, the upper end of the hollow box is provided with the first liquid inlet pipe, the first liquid inlet pipe is provided with the first valve body, the lower end of the hollow box is fixedly connected with the evenly distributed diversion cylinders in a penetrating manner, the sidewall of the diversion cylinders is provided with the second valve body at the lower part, the lower end of the diversion cylinders is fixedly connected with the liquid outlet needle, the sidewall of the diversion cylinders is fixedly connected with the fixing ring at the upper part, the side of the hollow box is fixedly connected with the air inlet pipe in a penetrating manner, the air inlet pipe is provided with the third valve body, the air outlet end of the air pump is connected to the air inlet end of the air inlet pipe through a hose, and the other end of the connecting pipe is screwed into the inner wall of the upper end of the first liquid inlet pipe.

[0008] Preferably, in use, the first valve body and the liquid suction pump are opened, the liquid suction pump draws the liquid medicine in the sealed tank into the hollow box, the liquid medicine enters the diversion cylinders under the action of gravity, the collection assembly is opened so that the collection bottles move upward, the liquid outlet needle can pass through the sterile rubber plug and enter the collection bottles to inject liquid, when it is needed to empty the hollow box, the first valve body is closed, the third valve body and the air pump are opened, the air pump injects pressure gas into the hollow box, the liquid in the hollow box can be emptied, and a plurality of liquid outlet needles can quickly fill a plurality of collection bottles, thereby solving the problem that the sterile filling device in the prior art is difficult to quickly empty the solution in the diversion mechanism and difficult to sterilely fill the bottles in a row.

[0009] Preferably, the left end of the support plate is fixedly connected with a connecting block, the left end of the connecting block is fixedly connected with a second bearing block, the upper and lower ends of the second bearing block are provided with evenly distributed through holes in a penetrating manner, the inner wall of the through holes is attached to the sidewall of the diversion cylinders, and the upper end of the second bearing block is attached to the lower end of the fixing ring.

[0010] Preferably, the diversion assembly further comprises a second liquid inlet pipe and a fourth valve body; the right end of the hollow box is fixedly connected with the second liquid inlet pipe in a penetrating manner, the hollow box is provided with the fourth valve body, the lower end of the sealed tank is fixedly connected with a second liquid outlet pipe, the second liquid outlet pipe is provided with a fifth valve body, and the lower end of the fifth valve body is connected to the inner wall of the right end of the hollow box through a hose.

[0011] Preferably, the upper end of the sealed tank is fixedly connected with a liquid injection pipe in a penetrating manner, and the liquid injection pipe is provided with a sixth valve body.

[0012] Preferably, the collection assembly comprises a U-shaped block, a rubber body, a placement groove, rubber protrusions, collection bottles and sterile rubber plugs; the upper end of the bearing plate is placed with the U-shaped block, the opening of the U-shaped block faces upward, the inner wall of the U-shaped block is fixedly connected with the rubber body at the bottom surface, the upper end of the rubber body is provided with evenly distributed placement grooves, the inner wall of the placement grooves is fixedly connected with evenly distributed rubber protrusions, the inner wall of the placement grooves is placed with the collection bottles, and the central axis of the sterile rubber plug is collinear with the central axis of the liquid outlet needle.

[0013] Preferably, handles are fixed to the edges of the upper end of the U-shaped block, and two limiting plates are fixed to the upper end of the bearing plate, and the ends of the two limiting plates close to each other are respectively attached to the left and right ends of the U-shaped block.

[0014] Preferably, the collecting assembly further comprises an electric cylinder, support legs are fixed to the edges of the lower end of the bearing plate, a bottom plate is fixed to the lower ends of the four support legs, the electric cylinder is fixed to the lower end of the bearing plate, the output shaft of the electric cylinder penetrates through the bearing plate and extends above the bearing plate, and the upper end of the output shaft of the electric cylinder is attached to the lower end of the U-shaped block.

[0015] The utility model discloses a beneficial effect: through opening first valve body and liquid pump, liquid pump is in the sealed jar Liquid is drawn into the hollow box, and the liquid enters the flow guide cylinder along the gravity, and opening collection assembly makes that the collecting bottle moves upward, and the liquid outlet needle can pass through the sterile rubber stopper and enter the collecting bottle and carry out liquid injection, needs to empty when the hollow box, closes first valve body, opens third valve body and air pump, and air pump injects pressure gas into the hollow box, can empty the liquid in the hollow box, and multiple liquid outlet needles can carry out the quick filling of multiple collecting bottles, solve the problem that the sterile filling device in the prior art is difficult to empty the solution in the flow guide mechanism quickly when using and is difficult to carry out the sterile filling of the whole row of bottle body. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 The utility model discloses a novel pharmaceutical sterile filling device's three -dimensional structure schematic diagram is shown;

[0017] Figure 2 The utility model discloses a novel pharmaceutical sterile filling device's flow guide subassembly's three -dimensional structure schematic diagram is shown;

[0018] Figure 3 The utility model discloses a novel pharmaceutical sterile filling device's second bearing block's three -dimensional structure schematic diagram is shown;

[0019] Figure 4 The utility model discloses a novel pharmaceutical sterile filling device's collecting assembly's three -dimensional structure schematic diagram is shown.

[0020] The marks in the drawings are: 1, bearing plate; 2, support plate; 3, first bearing block; 4, sealed tank; 5, liquid pump; 6, flow guide assembly; 601, hollow box; 602, first liquid inlet pipe; 603, first valve body; 604, flow guide cylinder; 605, second valve body; 606, liquid outlet needle; 607, fixing ring; 608, air inlet pipe; 609, third valve body; 610, second liquid inlet pipe; 611, fourth valve body; 7, air pump; 8, support leg; 9, bottom plate; 10, electric cylinder; 11, limiting plate; 12, first liquid outlet pipe; 13, connecting pipe; 14, second liquid outlet pipe; 15, fifth valve body; 16, connecting block; 17, second bearing block; 18, through hole; 19, U-shaped block; 20, rubber body; 21, placing groove; 22, rubber protrusion; 23, collection bottle; 24, sterile rubber plug; 25, handle; 26, liquid injection pipe; 27, sixth valve body. DETAILED DESCRIPTION

[0021] The utility model is further explained in connection with the drawings and examples.

[0022] Please refer to Figures 1-4 The utility model provides a new pharmaceutical sterile filling device, including bearing plate 1, collection bottle 23, support plate 2 of fixed connection on the upper end of bearing plate 1 and first bearing block 3 of fixed connection on the upper end of support plate 2, the upper end of first bearing block 3 is fixedly connected with sealed tank 4 and liquid pump 5, and the liquid end pipeline of liquid pump 5 is connected to the liquid outlet end of the lower part of the side wall of sealed tank 4, and the left end of support plate 2 is provided with flow guide assembly 6, and the side wall of first bearing block 3 is fixedly connected with air pump 7, and the upper end of bearing plate 1 is provided with collection assembly, and the upper end of collection bottle 23 is fixedly connected with sterile rubber plug 24 in the mode of penetrating, and one end of first liquid outlet pipe 12 is installed on the liquid outlet end of liquid pump 5, and one end of connecting pipe 13 is screw-mounted on the other end inner wall of first liquid outlet pipe 12,

[0023] Flow guide assembly 6 includes hollow box 601, first liquid inlet pipe 602, first valve body 603, flow guide cylinder 604, second valve body 605, liquid outlet needle 606, fixing ring 607, air inlet pipe 608 and third valve body 609, the left of support plate 2 is provided with hollow box 601, the upper end of hollow box 601 is installed with first liquid inlet pipe 602, and first valve body 603 is arranged on first liquid inlet pipe 602, and the lower end of hollow box 601 is fixedly connected with evenly distributed flow guide cylinder 604 in the mode of penetrating, and the lower part of the side wall of flow guide cylinder 604 is provided with second valve body 605, and the lower end of flow guide cylinder 604 is fixedly connected with liquid outlet needle 606, and the upper part of the side wall of flow guide cylinder 604 is fixedly connected with fixing ring 607, and air inlet pipe 608 is fixedly connected on one side of hollow box 601 in the mode of penetrating, and third valve body 609 is arranged on air inlet pipe 608, and the air outlet end of air pump 7 is connected to the air inlet end of air inlet pipe 608 through hose, and the other end of connecting pipe 13 is screw-mounted on the upper end inner wall of first liquid inlet pipe 602.

[0024] In use, the first valve body 603 and the liquid pump 5 are opened, the liquid pump 5 draws the liquid medicine in the sealed tank 4 into the hollow box 601, the liquid medicine enters the flow guide cylinder 604 under gravity, the collection assembly is opened so that the collection bottle 23 moves upward, the liquid outlet needle 606 can pass through the sterile rubber plug 24 to enter the collection bottle 23 to inject liquid, when it is needed to empty the hollow box 601, the first valve body 603 is closed, the third valve body 609 and the air pump 7 are opened, the air pump 7 injects pressure gas into the hollow box 601, and the liquid in the hollow box 601 can be emptied, and a plurality of liquid outlet needles 606 can quickly fill a plurality of collection bottles 23.

[0025] Please refer to Figure 1 and Figure 3 In the embodiment, the left middle part of the support plate 2 is fixedly connected with the connecting block 16, the left end of the connecting block 16 is fixedly connected with the second bearing block 17, the upper and lower ends of the second bearing block 17 are penetrated and uniformly distributed with the through holes 18, the inner walls of the through holes 18 are attached to the side walls of the flow guide cylinder 604, and the upper end of the second bearing block 17 is attached to the lower end of the fixed ring 607, so that the flow guide cylinder 604 is stably placed.

[0026] Please refer to Figure 1 and Figure 2 In the embodiment, the flow guide assembly 6 further comprises the second liquid inlet pipe 610 and the fourth valve body 611, the right end of the hollow box 601 is fixedly connected with the second liquid inlet pipe 610 in a penetrating mode, the fourth valve body 611 is arranged on the hollow box 601, the lower end of the sealed tank 4 is fixedly connected with the second liquid outlet pipe 14, the fifth valve body 15 is arranged on the second liquid outlet pipe 14, the lower end of the fifth valve body 15 is connected to the right end inner wall of the hollow box 601 through a hose, and opening of the fifth valve body 15 can place the liquid medicine in the sealed tank 4 into the hollow box 601 through the hose and the second liquid inlet pipe 610, so that the liquid inlet is accelerated.

[0027] Please refer to Figure 1 and Figure 4 In the embodiment, the upper end of the sealed tank 4 is fixedly connected with the liquid injection pipe 26 in a penetrating mode, and the sixth valve body 27 is arranged on the liquid injection pipe 26, so that the liquid injection pipe 26 can conveniently inject liquid into the sealed tank 4.

[0028] Please refer to Figure 1 and Figure 4In the embodiment, the collecting assembly comprises a U-shaped block 19, a rubber body 20, placing grooves 21, rubber protrusions 22, a collecting bottle 23 and a sterile rubber plug 24; the upper end of the bearing plate 1 is provided with the U-shaped block 19, the opening of the U-shaped block 19 faces upward, the inner wall of the U-shaped block 19 is fixedly connected with the rubber body 20, the upper end of the rubber body 20 is provided with the uniformly distributed placing grooves 21, the inner wall of the placing grooves 21 is fixedly connected with the uniformly distributed rubber protrusions 22, the inner wall of the placing grooves 21 is provided with the collecting bottle 23, the central axis of the sterile rubber plug 24 is collinear with the central axis of the liquid outlet needle 606, the filling is performed in a sterile chamber, the U-shaped block 19 is placed on the upper end of the bearing plate 1, so that the central axis of the sterile rubber plug 24 is collinear with the central axis of the liquid outlet needle 606, when the collecting bottle 23 moves upward, the liquid outlet needle 606 penetrates through the sterile rubber plug 24 and enters the inside of the collecting bottle 23, thereby facilitating the liquid injection into the inside of the collecting bottle 23.

[0029] Please refer to Figure 1 and Figure 4 In the embodiment, the upper end of the U-shaped block 19 is fixedly connected with the handle 25 on both sides, the upper end of the bearing plate 1 is fixedly connected with the two limiting plates 11, and the ends of the two limiting plates 11 close to each other are respectively attached to the left and right ends of the U-shaped block 19, thereby facilitating the stable movement of the U-shaped block 19.

[0030] Please refer to Figure 1 and Figure 4 In the embodiment, the collecting assembly further comprises the electric cylinder 10, the lower end of the bearing plate 1 is fixedly connected with the supporting legs 8 at the four corner edges, the lower ends of the four supporting legs 8 are fixedly connected with the bottom plate 9, the lower end of the bearing plate 1 is fixedly connected with the electric cylinder 10, the output shaft of the electric cylinder 10 penetrates through the bearing plate 1 and extends above the bearing plate 1, the upper end of the output shaft of the electric cylinder 10 is attached to the lower end of the U-shaped block 19, when the electric cylinder 10 is turned on and the output shaft of the electric cylinder 10 moves upward, the U-shaped block 19 can be pushed upward, thereby facilitating the upward movement of the U-shaped block 19, the liquid outlet needle 606 is inserted into the inside of the sterile rubber plug 24, and the liquid injection into the collecting bottle 23 is facilitated.

[0031] Working principle: firstly, the filling is performed in a sterile chamber, the U-shaped block 19 is placed on the upper end of the bearing plate 1, so that the central axis of the sterile rubber plug 24 is collinear with the central axis of the liquid outlet needle 606, when the collecting bottle 23 moves upward, the liquid outlet needle 606 penetrates through the sterile rubber plug 24 and enters the inside of the collecting bottle 23;

[0032] Then the first valve body 603 and the liquid suction pump 5 are turned on, the liquid suction pump 5 sucks the liquid in the sealing tank 4 into the hollow box 601, and the liquid enters the flow guide cylinder 604 under the action of gravity.

[0033] Then, the electric cylinder 10 is opened to make the output shaft of the electric cylinder 10 move upward, push the U-shaped block 19 upward, realize the upward movement of the U-shaped block 19, make the liquid outlet needle 606 insert into the inside of the sterile rubber plug 24, and open the second valve body 605 to inject liquid into the collection bottle 23;

[0034] When it is needed to empty the hollow box 601, the first valve body 603 is closed, the third valve body 609 and the air pump 7 are opened, the air pump 7 injects pressure gas into the hollow box 601, and the liquid in the hollow box 601 can be emptied;

[0035] The plurality of liquid outlet needles 606 can quickly fill the plurality of collection bottles 23, in addition, the liquid in the sealed tank 4 can be placed into the inside of the hollow box 601 through the hose and the second liquid inlet pipe 610 by opening the fifth valve body 15, and the liquid inlet can be accelerated.

[0036] The embodiments of the utility model are described in detail in combination with the drawings above, but the utility model is not limited to the above-mentioned embodiments, and various changes can be made within the knowledge range possessed by the person skilled in the art without departing from the purpose of the utility model.

Claims

1. A novel pharmaceutical aseptic filling device, comprising a support plate (1), a collection bottle (23), a support plate (2) fixed to the upper end of the support plate (1), and a first support block (3) fixed to the upper end of the support plate (2); characterized in that: The upper end of the first support block (3) is fixedly connected to a sealed tank (4) and a liquid pump (5). The liquid pump (5) is connected to the liquid outlet at the lower side wall of the sealed tank (4). The left end of the support plate (2) is provided with a flow guide assembly (6). The side wall of the first support block (3) is fixedly connected to an air pump (7). The upper end of the support plate (1) is provided with a collection assembly. The upper end of the collection bottle (23) is fixedly connected with a sterile rubber stopper (24). The liquid outlet of the liquid pump (5) is installed with one end of the first liquid outlet pipe (12). The other end of the first liquid outlet pipe (12) is threaded with one end of the connecting pipe (13). The flow guiding assembly (6) includes a hollow box (601), a first inlet pipe (602), a first valve body (603), a flow guiding tube (604), a second valve body (605), an outlet needle (606), a fixing ring (607), an air inlet pipe (608), and a third valve body (609); a hollow box (601) is provided on the left side of the support plate (2), the first inlet pipe (602) is installed on the upper end of the hollow box (601), the first valve body (603) is provided on the first inlet pipe (602), and a uniformly distributed flow guiding tube is fixedly connected through the lower end of the hollow box (601). The lower part of the side wall of the tube (604) is provided with a second valve body (605), the lower end of the tube (604) is fixedly connected with a liquid outlet needle (606), the upper part of the side wall of the tube (604) is fixedly connected with a fixing ring (607), the side of the hollow box (601) is fixedly connected with an air inlet pipe (608), the air inlet pipe (608) is provided with a third valve body (609), the air outlet of the air pump (7) is connected to the air inlet of the air inlet pipe (608) through a hose, and the other end of the connecting pipe (13) is threaded to the upper inner wall of the first liquid inlet pipe (602).

2. The novel pharmaceutical aseptic filling device according to claim 1, characterized in that: A connecting block (16) is fixed to the middle of the left end of the support plate (2), and a second bearing block (17) is fixed to the left end of the connecting block (16). The upper and lower ends of the second bearing block (17) are provided with evenly distributed through holes (18). The inner wall of the through hole (18) is in contact with the side wall of the guide tube (604), and the upper end of the second bearing block (17) is in contact with the lower end of the fixing ring (607).

3. The novel pharmaceutical aseptic filling device according to claim 1, characterized in that: The flow guiding assembly (6) also includes a second inlet pipe (610) and a fourth valve body (611); the second inlet pipe (610) is fixedly connected through the right end of the hollow box (601), the fourth valve body (611) is provided on the hollow box (601), the lower end of the sealed tank (4) is fixedly connected to a second outlet pipe (14), the second outlet pipe (14) is provided with a fifth valve body (15), and the lower end of the fifth valve body (15) is connected to the inner wall of the right end of the hollow box (601) through a hose.

4. The novel pharmaceutical aseptic filling device according to claim 1, characterized in that: A liquid injection pipe (26) is fixedly connected to the upper end of the sealed container (4), and a sixth valve body (27) is provided on the liquid injection pipe (26).

5. The novel pharmaceutical aseptic filling device according to claim 1, characterized in that: The collection assembly includes a U-shaped block (19), a rubber body (20), a placement groove (21), rubber protrusions (22), a collection bottle (23), and a sterile rubber stopper (24). A U-shaped block (19) is placed on the upper end of the support plate (1), with the opening of the U-shaped block (19) facing upward. A rubber body (20) is fixed to the bottom surface of the inner wall of the U-shaped block (19). A placement groove (21) is evenly distributed on the upper end of the rubber body (20). A rubber protrusion (22) is evenly distributed on the inner wall of the placement groove (21). A collection bottle (23) is placed on the inner wall of the placement groove (21). The central axis of the sterile rubber stopper (24) and the central axis of the dispensing needle (606) are collinear.

6. A novel pharmaceutical aseptic filling device according to claim 5, characterized in that: Handles (25) are fixed to both sides of the upper end of the U-shaped block (19). Two limiting plates (11) are fixed to the upper end of the bearing plate (1). The ends of the two limiting plates (11) that are close to each other are respectively attached to the left and right ends of the U-shaped block (19).

7. A novel pharmaceutical aseptic filling device according to claim 5, characterized in that: The collection assembly also includes an electric cylinder (10), and support legs (8) are fixed to the four corner edges of the lower end of the support plate (1). The lower ends of the four support legs (8) are fixed to a base plate (9). The lower end of the support plate (1) is fixed to an electric cylinder (10). The output shaft of the electric cylinder (10) passes through the support plate (1) and extends to the top of the support plate (1). The upper end of the output shaft of the electric cylinder (10) is in contact with the lower end of the U-shaped block (19).

Images