Brain stereotactic skull leveling device

By designing a stereotactic cranial leveling device for brain positioning, and utilizing ear rod limiting and motor drive, the cumbersome problem of cranial leveling in existing technologies has been solved, enabling rapid leveling of mouse skulls and improving the efficiency of brain science research.

CN223601564UActive Publication Date: 2025-11-28SHENZHEN QINYE PHARM TECH CO LTD
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Patent Information

Application Number
CN202422602736.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-28
Publication Date
2025-11-28
Estimated Expiration
2034-10-28

AI Technical Summary

Technical Problem

In existing technologies, the operation of stereotaxic instruments for adjusting the horizontal plane of the skull is cumbersome, time-consuming, and labor-intensive, making it difficult to quickly locate the horizontal plane of the skull, which affects the efficiency of brain science research.

Method used

A stereotactic cranial leveling device for brain positioning was designed, including a fixed part and an adjustable part. The mouse head is limited by an ear rod, and combined with rotation and testing parts, the cranium is quickly leveled through a pressure sensing module and a motor drive.

Benefits of technology

This method enables rapid leveling of the mouse skull, shortens experimental time, simplifies procedures, and improves experimental efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a brain stereotactic skull leveling device which comprises a bottom plate, and a base and a wireless control display screen are fixedly installed on the top of the bottom plate. The internal structure of the pressure contact pin comprises a pin head, a spring and a pressure sensing module, the compression amount of the spring, namely the displacement amount of the pin head, is calculated according to the pressure borne by the pressure sensing module, namely the elastic force of the spring, and under the matched use of a brain map, after the position is adjusted in the X and Y directions, the pressure sensing module can be used for sensing the pressure. The method comprises the following steps: taking a mouse as a skull, taking the position of a fontangle as a coordinate origin (0, 0, 0), driving a pressure contact needle to move by utilizing a motor I and a motor II according to the origin, detecting coordinates (0, Y, Z1), (X, 0, Z2) and (-X, 0, Z3) of other three sites on the skull, and leveling the horizontal plane of the mouse skull to an allowable error range according to a data difference value of a Z axis in the coordinates, and the effect of quickly leveling the horizontal plane of the skull of the mouse is achieved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of brain science research, concretely is brain stereotaxy skull leveling device. BACKGROUND

[0002] Brain stereotaxy technology is widely used in the precise positioning of brain damage, stimulation and electroencephalogram recording, and becomes an indispensable tool for studying brain structure and function. Brain stereotaxy technology mainly uses brain stereotaxy instrument as a positioning instrument, uses a three-dimensional coordinate system defined by certain external markers of the skull (such as the anterior fontanel, the posterior fontanel, the external auditory canal, the eye socket, the sagittal suture, etc.) or other reference points to determine the position of certain neural structures under the cortex, so as to perform directional stimulation, destruction, injection of drugs, guidance of potential and other researches under non-direct exposure, and is an important research method in the fields of neuroanatomy, neurophysiology, neuropharmacology and neurosurgery.

[0003] In the research process of brain science field, the indispensable instrument is brain stereotaxy instrument, and precise positioning injection can be realized with the help of brain atlas. First, the mouse is fixed on the adapter, the needle of the micro-injection pump is used to contact the skull of the mouse, and then the coordinate position of the skull is judged. According to the mouse brain (anterior fontanel), the coordinate (0, 0, 0) point is required, and the skull is required to be adjusted to be a horizontal plane. Then, according to the corresponding point coordinates on the brain atlas, the target point is positioned. Among them, the requirement that the anterior fontanel and the two points of the herringbone point are on the same horizontal plane and the left and right brain symmetrical on the same horizontal plane. However, the operation method is complicated and the experimental time is long, from fixing the mouse to leveling, the required time is 40-60 minutes, at present, there is no good method to quickly position the skull plane, mainly manual positioning instrument repeatedly measures, repeatedly adjusts, the operation is complex, time-consuming and laborious, and this problem has become a pain point and difficulty for the laboratory personnel to position the target point in brain science research. UTILITY MODEL CONTENTS

[0004] The utility model aims at providing brain stereotaxy skull leveling device, achieves the purpose of solving the problem in the background art.

[0005] In order to achieve the above object, the utility model provides the following technical scheme: brain stereotaxy skull leveling device, including bottom plate, the top of the bottom plate is fixedly installed with base, wireless control display screen, the wireless control display screen is arranged at the right side of the base;

[0006] Adjusting and adapting assembly, the adjusting and adapting assembly is arranged at the top of the bottom plate;

[0007] Among them, the adjusting and adapting assembly includes fixed position, adjusting position, the fixed position and adjusting position are arranged at the top of the bottom plate;

[0008] A fixed-point test assembly is arranged on the top of the bottom plate.

[0009] The fixed-point test assembly comprises a rotating part and a test part, which are arranged on the top of the bottom plate.

[0010] Preferably, the fixing part comprises a clamping rod, the top of the bottom plate is provided with a U-shaped frame, the top of the U-shaped frame is fixedly provided with a fixing seat, a square column is movably arranged in the U-shaped frame, a clamping piece is movably arranged in the U-shaped frame, a rotating rod is movably arranged in the fixing seat in a threaded manner, the clamping rod is movably arranged in the fixing seat, clamping holes are linearly and equidistantly arranged in the square column and the U-shaped frame, the clamping piece is arranged in the clamping hole, and one end of the rotating rod is in contact with one end of the clamping rod.

[0011] Preferably, the adjusting part comprises a base frame, the base frame is fixedly provided with a first speed reducer, the top of the bottom plate is provided with a movable plate, both sides of the movable plate are fixedly provided with rotating shafts, the output end of the first speed reducer is fixedly provided with a connecting piece, the left end of the connecting piece is fixedly provided with a short column, the top of the bottom plate is movably provided with a lifting plate, the bottom of the lifting plate is fixedly provided with an extension rod, and one end of the rotating shaft is fixedly provided with a second speed reducer.

[0012] Preferably, the base frame is fixedly arranged in the bottom plate, the movable plate is movably arranged on the top of the lifting plate, the rotating shaft is movably arranged between the lifting plate, the left end of the short column is fixedly arranged in the U-shaped frame, the lifting plate is movably arranged on the top of the bottom plate, the extension rod is fixedly arranged in the bottom plate, and the second speed reducer is fixedly arranged on one side of the lifting plate.

[0013] Preferably, the rotating part comprises a movable seat, a base plate is movably arranged in the movable seat, an arc plate is movably arranged in the movable seat, a threaded rod is movably arranged in the arc plate, a rotating wheel is fixedly arranged at the left end of the threaded rod, a connecting column is fixedly arranged on the top of the base plate, a cylinder is arranged on the top of the bottom plate, and a fixing frame is fixedly arranged in the middle of the cylinder.

[0014] Preferably, the movable seat is movably arranged on the top of the base, the threaded rod and the connecting column are movably arranged in the interior of the movable seat, the left end of the threaded rod extends to the outside of the movable seat, the telescopic end of the air cylinder is fixedly arranged on the movable seat, and the fixed frame is fixedly arranged on the top of the base.

[0015] Preferably, the test part comprises a frame, a threaded column one is movably arranged in the interior of the frame, a motor one is arranged on the top of the base plate, a threaded seat is fixedly arranged on the right side of the motor one, a threaded column two is fixedly arranged on the output end of the motor one, a horizontal rod is fixedly arranged on the right side of the threaded seat, a motor two is fixedly arranged on the top end of the threaded column one, a support is movably arranged on the middle portion of the threaded column two, and a pressure contact needle is fixedly arranged on one side of the support; the pressure contact needle is located directly above the center of the U-shaped frame and is used in cooperation with a brain atlas, the threaded column one and the threaded column two are driven to rotate by the motor one and the motor two, the pressure contact needle moves along the X and Y axes, the head of the mouse is fixed on the center of the U-shaped frame, the needle is overlapped with the bregma of the mouse, and the needle is contacted under the action of the motor two, so that the skull positioning is completed, the mouse skull level is quickly leveled, and the experimental time is shortened.

[0016] Preferably, the frame is fixedly arranged on the top of the connecting column, the frame and the movable seat are movably arranged, the threaded column one and the threaded seat are movably arranged through threads, the threaded seat and the threaded column two are movably arranged, the right end of the threaded column two is movably arranged with a side plate, the right end of the horizontal rod is fixedly arranged with the side plate, the horizontal rod and the support are movably arranged, and the wireless control display screens are electrically connected with the motor one, the motor two, the pressure contact needle, the speed reducer motor one, the telescopic rod, the speed reducer motor two and the air cylinder.

[0017] The brain stereotactic skull leveling device has the following beneficial effects:

[0018] (1) The interior structure of the pressure contact needle comprises a needle head, a spring and a pressure sensing module, the compression amount of the spring, that is, the displacement amount of the needle head, is calculated according to the pressure, that is, the elastic force of the spring, received by the pressure sensing module, the position is adjusted in the X and Y directions after the cooperation of the brain atlas, the bregma position is taken as the coordinate origin (0, 0, 0), the pressure contact needle is moved by the motor one and the motor two according to the origin, the coordinates (0, Y, Z1) and (X, 0, Z2) and (-X, 0, Z3) of the remaining three points on the skull are detected, the mouse skull level is leveled to the allowable error range according to the data difference value of the Z axis in the coordinates, and the mouse skull level can be quickly leveled.

[0019] (2), the utility model discloses a fixed part is provided, the right -hand member of square column is fixedly installed with ear lever, after the mouse of anaesthesia is placed at the top of lifting plate, when the head position angle of mouse is adjusted, using ear lever inserts mouse external auditory meatus, through the limiting of card piece to square column, the head of mouse is limited, the head of mouse is at the center position of U -shaped frame at this moment, reached convenient mouse limiting, the effect of convenient experiment operation. BRIEF DESCRIPTION OF DRAWINGS

[0020] Figure 1 It is the structure schematic diagram of the utility model;

[0021] Figure 2 It is the right -hand member inside structure of the utility model leveling device;

[0022] Figure 3 It is the front view of the utility model leveling device;

[0023] Figure 4 It is the utility model Figure 2 The partial enlarged view of A;

[0024] Figure 5 It is the utility model Figure 3 The partial enlarged view of B.

[0025] In the drawing: 1 bottom plate, 2 base, 3 adjusting adaptation assembly, 31 fixed part, 311 abutting rod, 312 U-shaped frame, 313 strut, 314 square column, 315 card piece, 316 rotating rod, 32 adjusting part, 321 telescopic rod, 322 ball, 323 movable plate, 324 rotating shaft, 325 limiting cylinder, 326 limiting plate, 327 clamping rod, 328 end block, 329 sleeve, 4 fixed point test assembly, 41 rotating part, 411 movable seat, 412 base plate, 413 arc plate, 414 threaded rod, 415 rotating wheel, 416 connecting column, 417 air cylinder, 418 fixed frame, 42 test part, 421 frame, 422 threaded column one, 423 motor one, 424 threaded seat, 425 threaded column two, 426 cross bar, 427 motor two, 428 support, 429 pressure contact needle. DETAILED DESCRIPTION

[0026] The technical scheme in the embodiments of the utility model will be described clearly and completely below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the utility model.

[0027] Examples of the described embodiments are illustrated in the accompanying drawings, throughout which like reference characters represent like elements or elements with similar functionality. The embodiments described below, and illustrated in the accompanying drawings, are exemplary and are intended to explain the present application, and are not to be understood as limiting the present application.

[0028] Embodiment one:

[0029] The preferred embodiment of the brain stereotactic skull leveling device provided by the present application is shown in the accompanying drawings, wherein the brain stereotactic skull leveling device comprises a bottom plate 1, a base 2 is fixedly installed on the top of the bottom plate 1, and a wireless control display screen 5 is arranged on the right side of the base 2. Figures 1-5

[0030] Adjusting and adapting assembly 3 is arranged on the top of the bottom plate 1.

[0031] Among them, the adjusting and adapting assembly 3 comprises a fixed part 31 and an adjusting part 32, both of which are arranged on the top of the bottom plate 1.

[0032] The fixed part 31 comprises a clamping rod 311, the top of the bottom plate 1 is provided with a U-shaped frame 312, the top of the U-shaped frame 312 is fixedly installed with a fixed seat 313, a square column 314 is movably installed in the inside of the U-shaped frame 312, a clamping piece 315 is movably installed in the inside of the U-shaped frame 312 through clamping, a rotating rod 316 is movably installed in the inside of the fixed seat 313 through screwing, the clamping rod 311 is movably installed in the inside of the fixed seat 313, the inside of the square column 314 and the U-shaped frame 312 are linearly and equidistantly provided with clamping holes, the clamping piece 315 is arranged in the inside of the clamping hole, and one end of the rotating rod 316 is in contact with one end of the clamping rod 311; the right end of the square column 314 is fixedly installed with an ear rod, the mouse after anesthesia is placed on the top of the lifting plate 327, when the head position angle of the mouse is adjusted, the ear rod is inserted into the external auditory canal of the mouse, the square column 314 is limited by the clamping piece 315, the head of the mouse is limited, and at this time the head of the mouse is in the center position of the U-shaped frame 312.

[0033] ​The adjusting part 32 comprises a base frame 321, a speed reducer motor 322 is fixedly installed in the base frame 321, the top of the bottom plate 1 is provided with a movable plate 323, the movable plate 323 is provided with a rotating shaft 324 on both sides, the output end of the speed reducer motor 322 is fixedly installed with a connecting piece 325, the left end of the connecting piece 325 is fixedly installed with a short column 326, the top of the bottom plate 1 is movably installed with a lifting plate 327, the bottom of the lifting plate 327 is fixedly installed with a telescopic rod 328, one end of the rotating shaft 324 is fixedly installed with a speed reducer motor 329, the base frame 321 is fixedly installed in the bottom plate 1, the movable plate 323 is movably installed on the top of the lifting plate 327, the rotating shaft 324 is movably installed between the lifting plate 327, the left end of the short column 326 is fixedly installed with the U-shaped frame 312, the lifting plate 327 is movably installed on the top of the bottom plate 1, the telescopic rod 328 is fixedly installed in the bottom plate 1, and the speed reducer motor 329 is fixedly installed on one side of the lifting plate 327; the head position of the mouse is on the top of the movable plate 323, since the rotating shaft 324 is arranged at the left end of the movable plate 323, when the speed reducer motor 329 is started, the right end of the movable plate 323 is lifted, the head of the mouse is lifted, when the head of the mouse is placed horizontally, the speed reducer motor 329 stops working, and then the rotating rod 316 is rotated, one end of the rotating rod 316 moves in the fixed seat 313, pushes the abutting rod 311, and the abutting rod 311 is limited to the mouse's incisors.

[0034] Embodiment two:

[0035] On the basis of the first embodiment, the preferred embodiment of the brain stereotactic skull leveling device provided by the utility model comprises Figures 1-5 As shown in the figure: the fixed-point testing assembly 4 is arranged on the top of the bottom plate 1.

[0036] The fixed-point testing assembly 4 comprises a rotating part 41 and a testing part 42, and the rotating part 41 and the testing part 42 are arranged on the top of the bottom plate 1.

[0037] The rotating part 41 comprises a movable seat 411, the inside of the movable seat 411 movably mounting a bottom disc 412, the inside of the movable seat 411 movably mounting an arc plate 413, the inside of the arc plate 413 movably mounting a threaded rod 414, the left end of the threaded rod 414 fixedly mounting a rotating wheel 415, the top of the bottom disc 412 fixedly mounting a connecting column 416, the top of the bottom plate 1 being provided with a cylinder 417, the middle of the cylinder 417 fixedly mounting a fixing frame 418, the movable seat 411 movably being mounted on the top of the base 2 through clamping, the threaded rod 414 and the connecting column 416 all movably being mounted in the inside of the movable seat 411, the left end of the threaded rod 414 penetrating through the movable seat 411 and extending to the outside of the movable seat 411, the telescopic end of the cylinder 417 fixedly mounting the movable seat 411, the fixing frame 418 fixedly mounting on the top of the base 2; the bottom disc 412 and the connecting column 416 movably mounting in the inside of the movable seat 411, the frame 421 thus can rotate, rotating the rotating wheel 415, since the threaded mounting between the threaded rod 414 and the movable seat 411, the threaded rod 414 will drive the sliding plate 413 to move, abutting and limiting the bottom disc 412, preventing the angle of the whole testing part 42 from changing, starting the cylinder 417, the movable seat 411 moving back and forth on the top of the base 2, driving the testing part 42 to move in the Y-axis direction;

[0038] The test site 42 comprises a frame 421, a threaded column one 422 movably mounted in the frame 421, a motor one 423 provided on the top of the bottom plate 1, a threaded seat 424 fixedly mounted on the right side of the motor one 423, a threaded column two 425 fixedly mounted on the output end of the motor one 423, a cross rod 426 fixedly mounted on the right side of the threaded seat 424, a motor two 427 fixedly mounted on the top end of the threaded column one 422, a support 428 movably mounted on the middle of the threaded column two 425, a pressure contact needle 429 fixedly mounted on one side of the support 428, the frame 421 being fixedly mounted on the top of the connecting column 416 and movably mounted between the movable seat 411, the threaded column one 422 and the threaded seat 424 being movably mounted through threads, the threaded seat 424 and the threaded column two 425 being movably mounted, a side plate movably mounted on the right end of the threaded column two 425, the right end of the cross rod 426 and the side plate being fixedly mounted, the cross rod 426 and the support 428 being movably mounted, and the wireless control display screen 5 being electrically connected between the motor one 423, the motor two 427, the pressure contact needle 429, the speed reducer motor one 322, the telescopic rod 328, the speed reducer motor two 329 and the air cylinder 418; the internal structure of the pressure contact needle 428 comprises a needle head, a spring and a pressure sensing module, the compression amount of the spring, i.e. the displacement amount of the needle head, is calculated according to the pressure, i.e. the elastic force of the spring, that the pressure sensing module will bear, under the cooperation of the brain atlas, the fontanelle position is taken as the coordinate origin (0, 0, 0), and the pressure contact needle 429 is moved by the motor one 423 and the motor two 427 according to the origin, so as to detect the coordinates (0, Y, Z1) and (X, 0, Z2) and (-X, 0, Z3) of the remaining three points on the skull, the mouse skull horizontal plane is leveled to the allowable error range according to the data difference value of the Z axis in the coordinates, and the specific operation is that the pressure contact needle 429 is moved to (X, 0, Z2), the speed reducer motor one 322 is started to drive the U-shaped frame 312 to rotate, the needle head at the point position is raised or lowered under the action of the spring, and accordingly the movement amount of the needle head can be calculated to adjust the Z1 value, and the adjustment of the other two points is similar.

[0039] In use, the right end of the square column 314 is fixedly provided with an ear lever, a mouse after anesthesia is placed on the top of the lifting plate 327, and the head of the mouse is positioned on the top of the movable plate 323. Since the rotating shaft 324 is arranged at the left end of the movable plate 323, when the second speed reducer 329 is started, the right end of the movable plate 323 is lifted, and the head of the mouse is lifted. When the head of the mouse is horizontally positioned, the second speed reducer 329 is stopped. The ear lever is inserted into the external auditory canal of the mouse, the square column 314 is limited by the clamping piece 315, the head of the mouse is limited, and the head of the mouse is positioned at the center of the U-shaped frame 312. Then, the rotating lever 316 is rotated, one end of the rotating lever 316 moves in the fixed seat 313, pushes the abutting lever 311, and the abutting lever 311 limits the mouse's incisors. The base plate 412 and the connecting column 416 are movably arranged in the movable seat 411, and the frame 421 can be rotated. The rotating wheel 415 is rotated, the threaded rod 414 is screw-connected with the movable seat 411, the sliding plate 413 is moved, the base plate 412 is abutted and limited, the angle of the entire test part 42 is prevented from changing, the cylinder 417 is started, the movable seat 411 moves on the top of the base 2, the test part 42 moves in the Y-axis direction, and the internal structure of the pressure contact needle 428 includes a needle, a spring and a pressure sensing module. According to the pressure that the pressure sensing module receives, that is, the elastic force of the spring, the compression amount of the spring is calculated, that is, the displacement amount of the needle. In the cooperation of the brain atlas, the fontanel position is used as the coordinate origin (0, 0, 0), and according to the origin, the motor 1 423 and the motor 2 427 drive the pressure contact needle 429 to move, detect the coordinates (0, Y, Z1) and (X, 0, Z2) and (-X, 0, Z3) of the remaining three points on the skull, and according to the data difference of the Z-axis in the coordinates, the mouse skull horizontal plane is leveled to the allowable error range. The specific operation is as follows: the pressure contact needle 429 is moved to (X, 0, Z2), the first speed reducer 322 is started, the U-shaped frame 312 is rotated, the needle at the point is lifted or lowered under the action of the spring, and the movement amount of the needle is calculated, so that the Z1 value is adjusted. The adjustment of the other two points is similar.

[0040] Finally, it should be noted that the above description is only a preferred embodiment of the present application and is not intended to limit the present application. Although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments or make equivalent replacements to some technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A stereotactic cranial skull leveling device, characterized in that, Including the bottom plate (1), the top of the bottom plate (1) is fixedly installed with the base (2), the wireless control display screen (5), the wireless control display screen (5) is arranged on the right side of the base (2); Adjusting the adaptive component (3), the adjusting adaptive component (3) is arranged on the top of the bottom plate (1); Wherein, the adjusting adaptive component (3) includes a fixed site (31), an adjusting site (32), the fixed site (31), the adjusting site (32) are arranged on the top of the bottom plate (1); The fixed point test component (4) is arranged on the top of the bottom plate (1); Wherein, the fixed point test component (4) includes a rotating site (41), a test site (42), the rotating site (41), the test site (42) are arranged on the top of the bottom plate (1).

2. A brain stereotactic skull leveling device according to claim 1, characterized in that: The fixed site (31) includes a close-together rod (311), the top of the bottom plate (1) is provided with a U-shaped frame (312), the top of the U-shaped frame (312) is fixedly installed with a fixed seat (313), the inside of the U-shaped frame (312) is movably installed with a square column (314), the inside of the U-shaped frame (312) is movably installed with a clamping piece (315), the inside of the fixed seat (313) is movably installed with a rotating rod (316), the close-together rod (311) is movably installed in the inside of the fixed seat (313), the inside of the square column (314), the U-shaped frame (312) is linearly equidistantly provided with a clamping hole, the clamping piece (315) is arranged in the clamping hole, one end of the rotating rod (316) is in contact with one end of the close-together rod (311).

3. The brain stereotactic skull leveling device of claim 1, wherein: The adjusting site (32) includes a chassis (321), the inside of the chassis (321) is fixedly installed with a speed reducer one (322), the top of the bottom plate (1) is provided with a movable plate (323), both sides of the movable plate (323) are fixedly installed with a rotating shaft (324), the output end of the speed reducer one (322) is fixedly installed with a connecting piece (325), the left end of the connecting piece (325) is fixedly installed with a short column (326), the top of the bottom plate (1) is movably installed with a lifting plate (327), the bottom of the lifting plate (327) is fixedly installed with a telescopic rod (328), one end of the rotating shaft (324) is fixedly installed with a speed reducer two (329).

4. A cranial stereotactic skull leveling device according to claim 3, wherein: The chassis (321) is fixedly installed in the inside of the bottom plate (1), the movable plate (323) is movably installed on the top of the lifting plate (327), the rotating shaft (324) is movably installed between the lifting plate (327), the left end of the short column (326) is fixedly installed with the U-shaped frame (312), the lifting plate (327) is movably installed on the top of the bottom plate (1), the telescopic rod (328) is fixedly installed in the inside of the bottom plate (1), the speed reducer two (329) is fixedly installed on one side of the lifting plate (327).

5. The brain stereotactic skull leveling device of claim 1, wherein: The rotating part (41) includes a movable seat (411), the inside of the movable seat (411) movably installs a chassis (412), the inside of the movable seat (411) movably installs an arc plate (413), the inside of the arc plate (413) movably installs a threaded rod (414), the left end of the threaded rod (414) fixedly installs a rotating wheel (415), the top of the chassis (412) fixedly installs a connecting column (416), the top of the bottom plate (1) is provided with a pneumatic cylinder (417), the middle of the pneumatic cylinder (417) fixedly installs a fixing frame (418).

6. A cranial stereotactic skull leveling device according to claim 5, wherein: The movable seat (411) is movably installed on the top of the base (2) through clamping, the threaded rod (414) and the connecting column (416) are movably installed in the inside of the movable seat (411), the left end of the threaded rod (414) penetrates through the movable seat (411) and extends to the outside of the movable seat (411), the telescopic end of the pneumatic cylinder (417) is fixedly installed with the movable seat (411), and the fixing frame (418) is fixedly installed on the top of the base (2).

7. The brain stereotactic skull leveling device of claim 1, wherein: The testing part (42) includes a frame (421), the inside of the frame (421) movably installs a threaded column one (422), the top of the bottom plate (1) is provided with a motor one (423), the right side of the motor one (423) fixedly installs a threaded seat (424), the output end of the motor one (423) fixedly installs a threaded column two (425), the right side of the threaded seat (424) fixedly installs a cross rod (426), the top end of the threaded column one (422) fixedly installs a motor two (427), the middle of the threaded column two (425) movably installs a support (428) through threads, and one side of the support (428) fixedly installs a pressure contact needle (429).

8. A cranial stereotactic skull leveling device according to claim 7, wherein: The frame (421) is fixedly installed on the top of the connecting column (416), and is movably installed between the movable seat (411); the threaded column one (422) and the threaded seat (424) are movably installed through threads, the threaded seat (424) and the threaded column two (425) are movably installed, the right end of the threaded column two (425) movably installs a side plate, the right end of the cross rod (426) is fixedly installed with the side plate, the cross rod (426) and the support (428) are movably installed, and the wireless control display screen (5) is electrically connected between the motor one (423), the motor two (427), the pressure contact needle (429), the speed reducer motor one (322), the telescopic rod (328), the speed reducer motor two (329) and the pneumatic cylinder (417).