Liquid preparation system with loop structure

Abstract

The utility model discloses a liquid preparation system with a loop structure, and relates to the technical field of pharmaceutical processes. Comprising a liquid preparation tank, a liquid storage tank and a loop structure, the loop structure is located between the liquid preparation tank and the liquid storage tank, an inlet pipeline and an outlet pipeline are further connected to the loop structure, a first valve is arranged on the pipeline between the liquid preparation tank and the loop structure, and a second valve is arranged on the pipeline between the liquid preparation tank and the loop structure. An eighth valve is arranged on the pipeline between the liquid storage tank and the loop structure, a third valve is arranged at the position, close to the loop structure, of the inlet pipeline, and a seventh valve is arranged at the position, close to the loop structure, of the outlet pipeline. After the loop structure is additionally arranged, 1-2 hours can be saved for complete cleaning and sterilization of each set of liquid preparation system, and the working efficiency can be effectively improved in a workshop with many liquid preparation systems.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of pharmaceutical process technology, and specifically relates to a liquid preparation system with loop structure. BACKGROUND

[0002] In the pharmaceutical process, the liquid preparation system is a relatively important system, and the liquid preparation system is usually composed of two tanks (a liquid preparation tank PT and a liquid storage tank ST), each of which is connected with one end of a pipeline, and the two pipelines are connected through some connections and finally connected in series to form a closed system. In the production process, cleaning and sterilization of the two pipelines are important operations, which are important procedures to ensure aseptic production.

[0003] As shown in the prior art liquid preparation system pipeline Figure 1 The liquid preparation tank cleaning and sterilization flow path is from valve 2 to valve 1, and the liquid storage tank cleaning and sterilization flow path is from valve 3 to valve 4. Because of the shared pipeline in the middle, the cleaning and sterilization of the pipelines of the liquid preparation tank and the liquid storage tank must be separated. Complete cleaning and sterilization of the liquid preparation system requires four procedures, namely, liquid preparation tank cleaning, liquid storage tank cleaning, liquid preparation tank sterilization, and liquid storage tank sterilization. The complete cleaning and sterilization of the entire liquid preparation system takes a long time, about 6-8 hours. SUMMARY

[0004] The utility model mainly aims at providing a liquid preparation system with loop structure to overcome the problems in the prior art.

[0005] To solve the above technical problems, the utility model adopts the following technical scheme:

[0006] A liquid preparation system with loop structure, comprising a liquid preparation tank, a liquid storage tank, and a loop structure, the loop structure being located between the liquid preparation tank and the liquid storage tank, the loop structure further being connected with an inlet pipeline and an outlet pipeline, a first valve being arranged on the pipeline between the liquid preparation tank and the loop structure, an eighth valve being arranged on the pipeline between the liquid storage tank and the loop structure, a third valve being arranged on the inlet pipeline close to the loop structure, and a seventh valve being arranged on the outlet pipeline close to the loop structure.

[0007] Further, the loop structure comprises four pipelines connected in sequence, namely a first pipeline, a second pipeline, a third pipeline, and a fourth pipeline.

[0008] Further, the first pipeline is located between the liquid preparation tank and the inlet pipeline, the second pipeline is located between the liquid preparation tank and the outlet pipeline, the third pipeline is located between the outlet pipeline and the liquid storage tank, and the fourth pipeline is located between the inlet pipeline and the liquid storage tank.

[0009] Further, the first pipeline is provided with a second valve, the second pipeline is provided with a fourth valve, the third pipeline is provided with a sixth valve, and the fourth pipeline is provided with a fifth valve.

[0010] Further, the outlet pipeline is provided with a temperature probe.

[0011] Compared with the prior art, the utility model has the following beneficial effects:

[0012] By increasing the loop structure, the complete cleaning and sterilization of each set of liquid preparation system can save 1-2 hours, and for the workshop with more liquid preparation systems, the work efficiency can be greatly improved. BRIEF DESCRIPTION OF DRAWINGS

[0013] Figure 1 It is a schematic diagram of the liquid preparation system in the prior art.

[0014] Figure 2 It is a schematic diagram of the liquid preparation system of the utility model.

[0015] Reference signs: 1, first valve; 2, second valve; 3, third valve; 4, fourth valve; 5, fifth valve; 6, sixth valve; 7, seventh valve; 8, eighth valve. DETAILED DESCRIPTION

[0016] The technical scheme of the utility model is further described below by means of drawings and examples.

[0017] In combination Figure 2 , the embodiment provides a liquid preparation system with a loop structure, wherein PT represents a liquid preparation tank, ST represents a liquid storage tank, and T represents a temperature probe.

[0018] The liquid preparation system of the embodiment specifically comprises a liquid preparation tank, a liquid storage tank and a loop structure, the loop structure is located between the liquid preparation tank and the liquid storage tank, the loop structure is further connected with an inlet pipeline and an outlet pipeline, a first valve 1 is arranged on the pipeline between the liquid preparation tank and the loop structure, an eighth valve 8 is arranged on the pipeline between the liquid storage tank and the loop structure, a third valve 3 is arranged on the inlet pipeline close to the loop structure, and a seventh valve 7 is arranged on the outlet pipeline close to the loop structure.

[0019] In the embodiment, the loop structure comprises four pipelines connected in sequence, namely a first pipeline, a second pipeline, a third pipeline and a fourth pipeline. The first pipeline is located between the liquid preparation tank and the inlet pipeline, the second pipeline is located between the liquid preparation tank and the outlet pipeline, the third pipeline is located between the outlet pipeline and the liquid storage tank, and the fourth pipeline is located between the inlet pipeline and the liquid storage tank. A second valve 2 is arranged on the first pipeline, a fourth valve 4 is arranged on the second pipeline, a sixth valve 6 is arranged on the third pipeline, and a fifth valve 5 is arranged on the fourth pipeline.

[0020] The liquid preparation system of the embodiment adds a loop structure, the flow path of the looped liquid preparation tank cleaning and sterilization is the first valve 1→the second valve 2→the fifth valve 5→the sixth valve 6→the seventh valve 7, the flow path of the non-looped liquid preparation tank cleaning and sterilization is the first valve 1→the fourth valve 4→the seventh valve 7, the flow path of the looped liquid storage tank cleaning and sterilization is the third valve 3→the second valve 2→the fourth valve 4→the seventh valve 7 and the third valve 3→the fifth valve 5→the eighth valve 8, and the flow path of the non-looped liquid storage tank cleaning and sterilization is the third valve 3→the fifth valve 5→the eighth valve 8.

[0021] According to the actual production condition, the flow path of the non-looped liquid preparation tank cleaning and sterilization and the flow path of the non-looped liquid storage tank cleaning and sterilization are two independent lines, and the two can be performed simultaneously, the complete cleaning and sterilization of the liquid preparation system needs three program times, namely, liquid preparation tank cleaning or liquid storage tank cleaning, liquid preparation tank cleaning and liquid storage tank sterilization or liquid storage tank cleaning and liquid preparation tank sterilization, and liquid preparation tank sterilization or liquid storage tank sterilization, one program time can be saved in production, the complete cleaning and sterilization of each set of liquid preparation system can save 1-2 hours, and for a workshop with more liquid preparation systems, the work efficiency can be greatly improved.

[0022] In a further embodiment, a temperature probe is arranged on the outlet pipeline. The temperature probe can monitor the temperature in the pipeline.

[0023] The above is only a preferred embodiment of the present application, and does not limit the technical scope of the present application, so any slight modification, equivalent change and modification made according to the technical essence of the present application to the above embodiment still belongs to the technical scope of the present application.

Claims

1. A liquid preparation system with a loop structure, characterized in that, The application relates to a liquid preparation device, which comprises a liquid preparation tank, a liquid storage tank and a loop structure, wherein the loop structure is arranged between the liquid preparation tank and the liquid storage tank, an inlet pipeline and an outlet pipeline are further connected to the loop structure, a first valve (1) is arranged on the pipeline between the liquid preparation tank and the loop structure, an eighth valve (8) is arranged on the pipeline between the liquid storage tank and the loop structure, a third valve (3) is arranged on the inlet pipeline close to the loop structure, and a seventh valve (7) is arranged on the outlet pipeline close to the loop structure.

2. The reconstitution system with a loop structure according to claim 1, wherein, The loop structure comprises four pipelines connected in sequence, namely a first pipeline, a second pipeline, a third pipeline and a fourth pipeline.

3. The reconstitution system with a loop structure according to claim 2, wherein, The first pipeline is arranged between the liquid preparation tank and the inlet pipeline, the second pipeline is arranged between the liquid preparation tank and the outlet pipeline, the third pipeline is arranged between the outlet pipeline and the liquid storage tank, and the fourth pipeline is arranged between the inlet pipeline and the liquid storage tank.

4. The reconstitution system with a loop structure according to claim 3, wherein, A second valve (2) is arranged on the first pipeline, a fourth valve (4) is arranged on the second pipeline, a sixth valve (6) is arranged on the third pipeline, and a fifth valve (5) is arranged on the fourth pipeline.

5. The reconstitution system with a loop structure according to claim 1, wherein, A temperature probe is arranged on the outlet pipeline.

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