Drug release capsule and capsule type endoscope
By using a memory metal adjustment component to control the temperature deformation of the drug cartridge in a capsule endoscope, the problem of drug release failure in capsule endoscopes has been solved, enabling targeted treatment of lesions in the digestive tract.
Patent Information
- Application Number
- CN202422961636.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-02
- Publication Date
- 2025-12-16
- Estimated Expiration
- 2034-12-02
AI Technical Summary
Existing capsule endoscopes lack drug delivery capabilities and cannot provide targeted treatment to detected lesions.
The regulating component, made of shape memory metal, is deformed by temperature control, which drives the drug chamber to move relative to the shielding component, exposing the drug outlet to release the drug.
It enables targeted drug release in specific areas of the digestive tract, thereby treating the affected areas.
Smart Images
Figure CN223667917U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to medical instrument technical field, especially release medicine capsule and capsule endoscope. BACKGROUND
[0002] As a new type of digestive tract examination instrument, compared with conventional gastroscopes, the capsule endoscope is a more convenient and comfortable examination instrument, and patients only need to swallow the capsule, which is painless, non-invasive and easy to be accepted by patients. Through magnetic control technology, the capsule endoscope can be controlled to move in the digestive tract, and the capsule can be applied to the examination of various parts of the upper digestive tract (esophagus, stomach and duodenum).
[0003] At present, most of the capsule endoscopes only have the function of examination, lack the function of drug release, and cannot perform targeted treatment on the detected lesion area. UTILITY MODEL CONTENT
[0004] The utility model provides a kind of release medicine capsule and capsule endoscope, when cooperating with capsule endoscope, it can release medicine in the specific area in digestive tract, to the lesion area detected by endoscope targeted treatment.
[0005] In a first aspect, the utility model provides a kind of release medicine capsule, comprising: medicine bin, the inside of medicine bin is formed with storage chamber, and medicine bin is provided with medicine outlet that communicates with storage chamber;Shielding piece, shielding piece is connected with medicine bin by adjusting piece, and shielding piece is used to shield medicine outlet;Wherein, adjusting piece is made of memory metal, and adjusting piece is configured to drive medicine bin to move relative to shielding piece when deforming, so that medicine outlet is exposed outside the shielding area of shielding piece.
[0006] In an embodiment, shielding piece is provided with conductive part, and conductive part is electrically connected with adjusting piece, and conductive part is used to energize adjusting piece, and adjusting piece is configured to heat and deform after energization.
[0007] In an embodiment, shielding piece is provided with first clamping structure, and medicine bin is provided with second clamping structure corresponding to first clamping structure;
[0008] When first clamping structure and second clamping structure are clamped, shielding piece shields medicine outlet.
[0009] In an embodiment, adjusting piece is provided as helical structure.
[0010] In an embodiment, shielding piece is covered outside medicine bin, and shielding piece is provided with opening;
[0011] Adjusting piece is configured to deform after heating to drive medicine bin to stretch out shielding piece from opening, so that medicine outlet is exposed.
[0012] In one embodiment, the outer surface of the cartridge comprises a first end surface facing the shielding member and an outer cylindrical surface, wherein the outer cylindrical surface is in abutment with the inner wall surface of the shielding member, and the first end surface and the shielding member enclose a receiving cavity, and the medicine outlet is arranged on the first end surface and / or the outer cylindrical surface.
[0013] In one embodiment, the adjusting member is located in the receiving cavity, and the adjusting member is connected to the first end surface.
[0014] In one embodiment, the first end surface is provided with a guide sleeve, the shielding member is provided with a guide column, the guide sleeve is sleeved outside the guide column, and the adjusting member is sleeved outside the guide sleeve.
[0015] In one embodiment, the shielding member is provided with a first clamping structure extending in the circumferential direction, the cartridge is provided with a second clamping structure extending in the circumferential direction, and the first clamping structure and the second clamping structure are matched to form a sealing structure surrounding the cartridge.
[0016] In a second aspect, the utility model also provides a capsule type endoscope, it includes: endoscope main part and above-mentioned release medicine capsule, release medicine capsule is connected with endoscope main part.
[0017] Compared with the prior art, the utility model has the advantages that since the adjusting member made of memory metal is arranged, when the target area is detected by the endoscope, the deformation degree of the adjusting member is controlled by adjusting the temperature of the adjusting member, so that the cartridge connected to the adjusting member is moved relative to the shielding member. The medicine outlet originally shielded by the shielding member is exposed, the release of the medicament in the cartridge is completed, and targeted treatment of the target area is realized. BRIEF DESCRIPTION OF DRAWINGS
[0018] In the following, the utility model will be described in more detail based on the embodiments and with reference to the drawings.
[0019] Figure 1 is the cross-sectional structure schematic view of the release medicine capsule in the embodiment of the utility model when the release medicine capsule is not releasing medicine;
[0020] Figure 2 is the cross-sectional structure schematic view of the release medicine capsule in the embodiment of the utility model when the release medicine capsule is releasing medicine;
[0021] Figure 3 is the three-dimensional structure schematic view of the cartridge in the embodiment of the utility model;
[0022] Figure 4 is the three-dimensional structure schematic view of the shielding member in the embodiment of the utility model;
[0023] Figure 5 is the three-dimensional structure schematic view of the shielding member in the embodiment of the utility model in the perspective view;
[0024] Figure 6 is Figure 1 a partial structural schematic view at A.
[0025] Reference signs:
[0026] 100, medicine bin; 110, medicine outlet; 120, second clamping structure; 130, first end surface; 140, outer cylindrical surface;
[0027] 200, shielding piece; 210, first clamping structure; 220, opening; 230, cylindrical portion; 231, inner wall surface; 240, semispherical portion;
[0028] 300, adjusting piece;
[0029] 400, conductive piece;
[0030] 500, guide sleeve; 510, window;
[0031] 600, guide column. DETAILED DESCRIPTION
[0032] The utility model will be further described below with reference to the drawings.
[0033] In the first aspect, referring to Figure 1 and Figure 2 , a medicine releasing capsule is provided, which comprises a medicine bin 100, a shielding piece 200 and an adjusting piece 300, the adjusting piece 300 is made of memory metal, and the shielding piece 200 is connected with the medicine bin 100 through the adjusting piece 300.
[0034] Referring to Figure 3 , the inside of the medicine bin 100 is formed with a medicine storage cavity, and the medicine bin 100 can store medicines in the medicine storage cavity during use. The medicine bin 100 has a medicine outlet 110 communicating with the medicine storage cavity, and the shielding piece 200 is used to shield the medicine outlet 110 to prevent the medicines in the medicine bin 100 from leaking.
[0035] Since the adjusting piece 300 is made of memory metal, the memory metal can automatically deform under a specific temperature environment and restore to a specific shape. When it is necessary to release the medicines, the temperature of the adjusting piece 300 can be adjusted to the deformation temperature, so as to drive the medicine bin 100 to move relative to the shielding piece 200, so that the shielding piece 200, which can originally shield the medicine outlet 110, cannot shield the medicine outlet 110, and the medicine outlet 110 is exposed outside the shielding area of the shielding piece 200. Thus, the medicines in the medicine bin 100 are released.
[0036] That is to say, the adjusting process only needs to control the temperature of the adjusting piece 300, and does not need to set a complex mechanical structure in the medicine releasing capsule, which is more conducive to miniaturizing the medicine releasing capsule.
[0037] Referring to Figure 1 As shown in some implementations, the shielding member 200 is not only arranged outside the medicine cartridge 100, but also is attached to the outer side of the medicine cartridge 100 where the medicine outlet 110 is arranged, so as to shield the medicine outlet 110.
[0038] It can be understood that in some other implementations, the shielding member 200 is not necessarily arranged outside the medicine cartridge 100, but can also be arranged inside the medicine cartridge 100, and the shielding member 200 is driven to move by the deformation of the adjusting member 300, so as to expose the medicine outlet 110 and release the medicine.
[0039] Even if the shielding member 200 is arranged outside the medicine cartridge 100, the shielding member 200 does not necessarily have to be arranged as a barrel-shaped structure as shown in the above embodiment, but can also be arranged as a plate-shaped structure attached to the outer side of the medicine cartridge 100. The medicine outlet 110 is covered by the shielding member 200 to prevent the medicine in the medicine cartridge 100 from leaking. When the medicine needs to be released, the medicine cartridge 100 can be moved along the extension direction of the shielding member 200 so that the medicine outlet 110 is misaligned with the shielding member 200 to expose the medicine outlet 110; or the medicine cartridge 100 can be moved away from the shielding member 200 along a direction perpendicular to the extension direction of the shielding member 200 so that the gap between the medicine outlet 110 and the shielding member 200 is increased, thereby exposing the medicine outlet 110 and releasing the medicine. Figure 1
[0040] In some implementations, the adjusting member 300 is made of a memory metal material. The specific memory metal material used in the adjusting member 300 is not particularly limited, and any one of copper-based memory alloy, nickel-titanium memory alloy, iron-based memory alloy, aluminum-based memory alloy, etc. can be selected.
[0041] Referring to Figure 4 and Figure 5 In some implementations, the shielding member 200 is provided with a conductive member 400, the conductive member 400 is electrically connected with the adjusting member 300, the conductive member 400 is used to electrify the adjusting member 300, and the adjusting member 300 is configured to deform by heating after being electrified.
[0042] In some implementations, the adjusting member 300 is made of a memory metal material. The specific memory metal material used in the adjusting member 300 is not particularly limited, and any one of copper-based memory alloy, nickel-titanium memory alloy, iron-based memory alloy, aluminum-based memory alloy, etc. can be selected.
[0043] The drug-release capsule can also be connected to an endoscope, and the conductive element 400 can be connected to the power supply and control circuit of the endoscope. This allows the endoscope's electrical energy to heat the adjusting element 300, and simultaneously control the timing of drug release while controlling the endoscope. This avoids placing the power supply or control circuit within the drug-release capsule, further reducing its size. The conductive element 400 partially passes through the obstruction element 200 and forms a contact. When the obstruction element 200 is connected to the endoscope, the contact of the conductive element 400 is electrically connected to the endoscope, achieving electrical connection between the conductive element 400 and the endoscope.
[0044] It is understandable that there are various ways to heat the regulating element 300, and it is not necessarily limited to directly energizing the regulating element 300. An electric heating wire can also be placed near the regulating element 300, and heating can be achieved by supplying power to the electric heating wire. Alternatively, the regulating element 300 can be heated through a chemical reaction, such as by reacting an acidic substance with an alkaline substance, or through other exothermic reactions.
[0045] See Figure 1 , Figure 3 as well as Figure 6 As shown, in some implementations, the blocking member 200 is provided with a first snap-fit structure 210, and the medicine container 100 is provided with a second snap-fit structure 120 corresponding to the first snap-fit structure 210. When the first snap-fit structure 210 and the second snap-fit structure 120 are snapped together, the blocking member 200 blocks the medicine outlet 110. That is to say, through the snap-fit of the first snap-fit structure 210 and the second snap-fit structure 120, the blocking member 200 is more secure in blocking the medicine outlet 110, preventing the medicine container 100 from falling off naturally.
[0046] See Figure 3 , Figure 5 as well as Figure 6 As shown, the first snap-fit structure 210 is a slot structure, while the second snap-fit structure 120 is a protrusion structure. The shielding member 200 and the medicine tank 100 are snap-fitted together by the second snap-fit structure 120 embedding into the first snap-fit structure 210. It is understandable that the first snap-fit structure 210 can also be a protrusion structure, and the second snap-fit structure 120 a slot structure, with the shielding member 200 and the medicine tank 100 snap-fitted together by the first snap-fit structure 210 embedding into the second snap-fit structure 120. Alternatively, both the first snap-fit structure 210 and the second snap-fit structure 120 can be configured with a portion being a slot and another portion being a protrusion, with the protrusion of the first snap-fit structure 210 embedded into the slot of the second snap-fit structure 120, and vice versa, to achieve the snap-fit connection of the first snap-fit structure 210.
[0047] It should be noted that the first clamping structure 210 and the second clamping structure 120 are configured to be separated when the adjusting member 300 is heated to a transition temperature, where the transition temperature refers to the temperature at which the adjusting member 300 deforms and recovers, which is determined according to the material of the adjusting member 300.
[0048] Referring to Figure 1 and Figure 2 , in some implementations, the adjusting member 300 is provided in a spiral structure. When the adjusting member 300 is heated and deformed, the spiral structure can have greater expansion and contraction in the length direction, thereby moving the cartridge 100 further and ensuring that the dispensing opening 110 is sufficiently exposed after the cartridge 100 is moved. The spiral structure can be a structure with a fixed spiral radius as shown in the figure, that is, the adjusting member 300 is made into a spring structure. The spiral structure can also be a structure with a variable spiral radius, such as a snail structure with a spiral radius that continuously decreases.
[0049] Referring to Figure 2 , Figure 3 and Figure 5 , in some implementations, the shielding member 200 is arranged outside the cartridge 100, and the shielding member 200 is provided with an opening 220; the adjusting member 300 is configured to deform after being heated to drive the cartridge 100 to extend out of the opening 220 of the shielding member 200, so that the dispensing opening 110 is exposed. That is, the cartridge 100 is accommodated inside the shielding member 200, and in the use process, the cartridge 100 can be protected better by avoiding being subjected to impact by using the shielding member 200. As shown in Figure 4 , the shielding member 200 includes a barrel portion 230 and a hemispherical portion 240, wherein the barrel portion 230 is connected to the hemispherical portion 240, and the opening 220 is formed on the side of the barrel portion 230 away from the hemispherical portion 240. The opening 220 formed by the barrel portion 230 limits the movement direction of the cartridge 100.
[0050] Referring to Figure 2 , Figure 3 and Figure 5 , in some implementations, the outer surface of the cartridge 100 includes a first end surface 130 facing the shielding member 200 and an outer cylindrical surface 140, wherein the outer cylindrical surface 140 is fitted with the inner wall surface 231 of the shielding member 200, and the first end surface 130 and the shielding member 200 form a receiving cavity, and the dispensing opening 110 is arranged on the first end surface 130 and / or the outer cylindrical surface 140.
[0051] That is, the dispensing opening 110 can be arranged on the first end surface 130 of the cartridge 100, or on the outer cylindrical surface 140, or on both the first end surface 130 and the outer cylindrical surface 140.
[0052] The medicine outlet 110 arranged at the outer cylindrical surface 140 is directly shielded by the shielding member 200 adhered to the outer cylindrical surface 140, and the medicine in the medicine cartridge 100 can be released only after the adjusting member 300 moves the medicine cartridge 100. The medicine outlet 110 arranged at the first end surface 130 can allow the medicine to flow from the medicine outlet 110 at the first end surface 130 to the receiving cavity, but the outer cylindrical surface 140 adheres to the inner wall surface 231, and the medicine in the receiving cavity cannot flow out. Only after the outer cylindrical surface 140 is separated from the inner wall surface 231 when the medicine cartridge 100 extends out of the opening 220, the medicine in the receiving cavity can flow out of the opening 220, and the release of the medicine is completed.
[0053] Referring to Figure 3 As shown in the figure, in some implementations, three medicine outlets 110 are arranged at the outer cylindrical surface 140, which can improve the speed of releasing the medicine compared to arranging only one medicine outlet 110. It can be understood that the number and aperture of the medicine outlets 110 can be adjusted according to the particle size and characteristics of the medicine.
[0054] Referring to Figure 1 and Figure 2 As shown in the figure, in some implementations, the adjusting member 300 is located in the receiving cavity, and the adjusting member 300 is connected to the first end surface 130. Arranging the adjusting member 300 in the receiving cavity avoids exposing the adjusting member 300 to the digestive tract of the human body during the process of swallowing the medicine, which can scratch the digestive tract. The connection between the adjusting member 300 and the medicine cartridge 100 can be a fixed connection mode such as clamping connection, adhesive connection or welding. The connection between the adjusting member 300 and the shielding member 200 can be a fixed connection mode such as clamping connection, adhesive connection or welding. That is, the shielding member 200 and the medicine cartridge 100 are fixedly connected to the adjusting member 300, and after the release of the medicine, the medicine cartridge 100 is still connected to the shielding member 200 through the adjusting member 300.
[0055] Referring to Figure 1 and Figure 2 As shown in the figure, in some implementations, the first end surface 130 is provided with a guide sleeve 500, the shielding member 200 is provided with a guide column 600, the guide sleeve 500 is sleeved outside the guide column 600, and the adjusting member 300 is sleeved outside the guide sleeve 500. Through the cooperation of the guide sleeve 500 and the guide column 600, the moving direction of the medicine cartridge 100 can be limited, and at the same time, the adjusting member 300 is sleeved outside the guide sleeve 500, which can also limit the position of the adjusting member 300 by the guide sleeve 500.
[0056] In some implementations, the guide sleeve 500 and the medicine cartridge 100 are integrally formed, and the shielding member 200 and the guide column 600 are integrally formed.
[0057] Referring to Figure 2 and Figure 3As shown, the inside of the guide column 600 is provided with a wire storage chamber, and the wire storage chamber is provided with an electric connection wire, one end of the electric connection wire is connected with the conductive part 400, and the other end of the electric connection wire extends out of the window 510 of the guide sleeve 500 and is electrically connected with the adjusting part 300 outside the guide sleeve 500. That is, the storage of the electric connection wire is realized through the wire storage chamber.
[0058] Referring to Figure 2 and Figure 3 As shown, the shielding part 200 is provided with a first clamping structure 210 extending in the circumferential direction, and the cartridge 100 is provided with a second clamping structure 120 extending in the circumferential direction, and the first clamping structure 210 cooperates with the second clamping structure 120 to form a sealing structure around the cartridge 100. That is, the cartridge 100 is sealed and connected on the shielding part 200 through the cooperation of the annular first clamping structure 210 and the annular second clamping structure 120.
[0059] Referring to Figure 3 As shown, the second clamping structure 120 is arranged at one end of the cartridge 100 away from the first end face 130.
[0060] In a second aspect, the utility model also provides a capsule endoscope, which comprises:
[0061] An endoscope main body; and the above-mentioned drug release capsule, which is connected with the endoscope main body.
[0062] When the capsule endoscope is used, the digestive system can be detected and photographed through the endoscope main body, and when the area needing treatment is detected, the drug release capsule can be controlled to release the medicament, so that the targeted treatment of the specific area is realized. The endoscope main body can be fixedly connected with the drug release capsule, and the connection mode between the endoscope main body and the drug release capsule can also be set as detachable connection.
[0063] Although the utility model has been described with reference to the preferred embodiments, various improvements can be made and equivalent parts can be replaced without departing from the scope of the utility model. In particular, as long as there is no structural conflict, each technical feature mentioned in each embodiment can be combined in any way. The utility model is not limited to the specific embodiments disclosed in the text, but includes all technical solutions falling within the scope of the claims.
Claims
1. A drug release capsule, characterized by, The application relates to a drug releasing capsule. The drug releasing capsule comprises a drug cartridge (100) having a drug storage cavity formed inside, and an outlet (110) of the drug cartridge (100) being communicated with the drug storage cavity; a shielding member (200) being connected with the drug cartridge (100) through an adjusting member (300), and the shielding member (200) being used for shielding the outlet (110). The adjusting member (300) is made of a memory metal, and the adjusting member (300) is configured to drive the drug cartridge (100) to move relative to the shielding member (200) when deformed, so that the outlet (110) is exposed outside a shielding area of the shielding member (200).
2. The drug releasing capsule according to claim 1, wherein the shielding member (200) is provided with an electrically conductive member (400) electrically connected with the adjusting member (300), the electrically conductive member (400) is used for electrifying the adjusting member (300), and the adjusting member (300) is configured to be deformed by heating after being electrified.
3. The drug releasing capsule according to claim 1, wherein the shielding member (200) is provided with a first clamping structure (210), and the drug cartridge (100) is provided with a second clamping structure (120) corresponding to the first clamping structure (210); and when the first clamping structure (210) is clamped with the second clamping structure (120), the shielding member (200) shields the outlet (110).
4. The drug releasing capsule according to claim 1, wherein the adjusting member (300) is provided in a spiral structure.
5. The drug releasing capsule according to any one of claims 1-4, wherein the shielding member (200) is arranged outside the drug cartridge (100), and the shielding member (200) is provided with an opening (220); and the adjusting member (300) is configured to be deformed after being heated, so as to drive the drug cartridge (100) to extend out of the shielding member (200) from the opening (220), and the outlet (110) is exposed.
6. The drug releasing capsule according to claim 5, wherein an outer surface of the drug cartridge (100) comprises a first end surface (130) facing the shielding member (200) and an outer cylindrical surface (140), the outer cylindrical surface (140) is attached to an inner wall surface (231) of the shielding member (200), the first end surface (130) and the shielding member (200) form a receiving cavity, and the outlet (110) is arranged on the first end surface (130) and / or the outer cylindrical surface (140).
7. The drug releasing capsule according to claim 6, wherein the adjusting member (300) is located in the receiving cavity, and the adjusting member (300) is connected with the first end surface (130).
8. The drug releasing capsule according to claim 6, wherein The first end face (130) is provided with a guide sleeve (500), the shielding piece (200) is provided with a guide column (600), the guide sleeve (500) is sleeved outside the guide column (600), and the adjusting piece (300) is sleeved outside the guide sleeve (500).
9. The drug release capsule according to claim 5, wherein, The shielding piece (200) is provided with a first clamping structure (210) extending in the circumferential direction, the cartridge (100) is provided with a second clamping structure (120) extending in the circumferential direction, and the first clamping structure (210) cooperates with the second clamping structure (120) to form a sealing structure surrounding the cartridge (100).
10. A capsule endoscope, characterized by, It comprises: an endoscope body; and The drug release capsule according to any one of claims 1-9, wherein the drug release capsule is connected to the endoscope body.