Dual-purpose system for liquid chromatography and ion chromatography

Abstract

The utility model discloses a liquid chromatography and ion chromatography dual-purpose system which comprises a mobile phase bottle, a liquid phase pump, a sample injector, a column oven, a detector and a waste liquid bottle which are sequentially communicated, a control valve is arranged at the joint of the column oven and the detector, and the detector comprises a liquid phase detector and a conductivity detector. A liquid outlet channel of the control valve is respectively connected with liquid inlets of the liquid phase detector and the conductivity detector, liquid outlets of the liquid phase detector and the conductivity detector are connected to a waste liquid bottle through connecting pipes, and data output ends of the liquid phase detector and the conductivity detector are respectively and electrically connected to a multi-channel data acquisition software operating system; a software operating system can reversely control linkage of all components, according to needs, a set of dual-purpose system can be adopted to achieve separation detection of liquid chromatography and ion chromatography, the dual-purpose system shares a liquid phase pump, a sample injector, a column oven, a waste liquid bottle and a data acquisition system, and the cost and occupied space for configuring the two systems are reduced.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of chromatographic separation and analysis, and particularly relates to a liquid chromatography and ion chromatography dual-purpose system. BACKGROUND

[0002] A liquid chromatography (HPLC) system is an analysis system for separating components of organic compounds, which separates components in a mixture by using the solubility, distribution coefficient, adsorption capacity, etc. of substances in a stationary phase and a mobile phase. An ion chromatography (IC) system is an analysis system for separating inorganic anions and cations, which separates ions in a sample by using ion exchange principles through anion-cation exchange columns. The liquid chromatography system and the ion chromatography system have similar structures, and both mainly include a mobile phase bottle, a liquid phase pump, a sample injector, a column oven, a detector, a waste liquid bottle and a data acquisition and processing system. Currently, when liquid chromatography and ion chromatography analysis are performed, two independent systems, i.e. an HPLC system and an IC system, are used. In detection activities with low utilization rates of the HPLC system and the IC system, the configuration cost of the two systems is high, the space occupied by the two systems is large, and the maintenance cost during use is increased. UTILITARY MODEL

[0003] In view of the problems in the above background art, the utility model aims to provide a liquid chromatography and ion chromatography dual-purpose system.

[0004] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme:

[0005] A liquid chromatography and ion chromatography dual-purpose system includes a mobile phase bottle, a liquid phase pump, a sample injector, a column oven, a detector and a waste liquid bottle connected in sequence, a control valve is arranged at the connection between the column oven and the detector, the detector includes a liquid phase detector and a conductivity detector, the liquid outlet channels of the control valve are connected to the liquid inlets of the liquid phase detector and the conductivity detector respectively, the liquid outlets of the liquid phase detector and the conductivity detector are connected to the waste liquid bottle through connecting pipes, and the data output ends of the liquid phase detector and the conductivity detector are electrically connected to a multi-channel data acquisition system respectively.

[0006] Further, the column oven is provided with two groups of chromatographic column interfaces on the liquid inlet side and the liquid outlet side respectively, and the chromatographic columns for liquid chromatography and ion chromatography are connected between the two groups of chromatographic column interfaces respectively.

[0007] Further, the control valve adopts a multi-way switching valve, the multi-way switching valve comprises a first liquid inlet channel, a second liquid inlet channel, a first liquid outlet channel and a second liquid outlet channel, the first liquid inlet channel is communicated with the first liquid outlet channel, and the second liquid inlet channel is communicated with the second liquid outlet channel; the first liquid inlet channel and the second liquid inlet channel are respectively connected with the outside of two groups of chromatographic column interfaces on the liquid outlet side of the column oven, and the first liquid outlet channel and the second liquid outlet channel are respectively connected with the liquid inlet ports of the liquid phase detector and the conductivity detector.

[0008] Further, a multi-way valve is arranged between the sample injector and the column oven, one side of the multi-way valve is communicated with the flow phase pipeline and the sample injector, and the other side of the multi-way valve is connected with the outside of the chromatographic column interfaces on the liquid inlet side of the column oven through flow channel switching.

[0009] Further, the liquid inlet port of the liquid phase pump is connected with a plurality of flow phase bottles through the multi-way valve, and the plurality of flow phase bottles are respectively used for different chromatographic analysis.

[0010] Further, the liquid phase detector and the conductivity detector are arranged in a detection box, and a liquid discharge interface is arranged on the detection box and connected with a waste liquid bottle through a connecting pipe.

[0011] Compared with the defects and deficiencies of the prior art, the utility model has the following beneficial effects:

[0012] The liquid phase chromatograph and the ion chromatograph share the liquid phase pump, the sample injector, the column oven, the waste liquid bottle and the data acquisition system, the liquid phase detector and the conductivity detector are connected in parallel in the system, a dual-purpose system is formed, liquid phase chromatography and ion chromatography analysis can be carried out respectively, the cost of configuring two systems is reduced, the occupied space is small, and cleaning and maintenance are facilitated. BRIEF DESCRIPTION OF DRAWINGS

[0013] Figure 1 is the structure schematic view of the dual-purpose system of the liquid phase chromatograph and the ion chromatograph provided by the utility model embodiment;

[0014] Figure 2 is the structure schematic view of the column oven provided by the utility model embodiment;

[0015] Figure 3 is the structure schematic view of the detection box and the waste liquid bottle connection provided by the utility model embodiment;

[0016] In the drawing: 1, flow phase bottle, 2, liquid phase pump, 3, sample injector, 4, column oven, 5, liquid phase detector, 6, conductivity detector, 7, waste liquid bottle, 8, multi-channel data acquisition system, 9, detection box, 10, multi-way valve, 11, control valve, 12, connecting pipe, 13, liquid discharge interface, 14, chromatographic column interface, 15, multi-way valve, 16, sample bottle. DETAILED DESCRIPTION

[0017] In order to make the purpose, technical scheme and advantages of the utility model clearer and more apparent, the utility model will be further described in detail below in combination with specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the utility model and not to limit the utility model.

[0018] As shown in Figure 1 , the utility model provides a kind of liquid chromatography and ion chromatography dual-purpose system, including mobile phase bottle 1, liquid phase pump 2, sample injector 3, column oven 4, liquid phase detector 5, conductive detector 6, waste bottle 7 and data acquisition system 8, mobile phase bottle 1, liquid phase pump 2, sample injector 3, column oven 4 are sequentially communicated, column oven 4 is connected with liquid phase detector 5 and conductive detector 6 respectively by control valve 11, and the liquid outlet of liquid phase detector 5 and conductive detector 6 is connected to waste bottle 7 by connecting pipe 12, and the data output end of liquid phase detector 5 and conductive detector 6 is electrically connected to multichannel data acquisition system 8 respectively.

[0019] Since liquid chromatography and ion chromatography are used, different chromatographic columns are used, so two groups of chromatographic column interfaces 14 are respectively arranged on the liquid inlet side and the liquid outlet side of column oven 4, referring to Figure 2 , the chromatographic column of liquid chromatography and ion chromatography is connected between the two groups of chromatographic column interfaces 14. To facilitate the connection of chromatographic column, multichannel valve 10 is arranged between sample injector 3 and column oven 4, one side of multichannel valve 10 is communicated with mobile phase pipeline and sample injector 3, and the other side of multichannel valve 10 is externally connected with chromatographic column interface 14 on the liquid inlet side of column oven 4 by flow path switching.

[0020] During detection, the sample is placed in sample bottle 16, then enters sample injector 3, and then enters detector for detection after passing through chromatographic column. To facilitate use, the liquid inlet of liquid phase pump 2 is connected with multiple mobile phase bottles 1 by multichannel valve 15, which are respectively used for different chromatographic analysis. After the product detected by detector, to facilitate the connection of connecting pipe 12, liquid phase detector 5 and conductive detector 6 are arranged in detection box 9, referring to Figure 3 , detection box 9 is provided with liquid discharge interface 13, the inlet end of liquid discharge interface 13 is connected with the liquid outlet of liquid phase detector 5 and conductive detector 6 in the interior of detection box 9 by connecting pipe, and the outlet end of liquid discharge interface 13 is connected with waste bottle 7 by connecting pipe 12 outside detection box 9.

[0021] In order to facilitate the control detection, the control valve 11 adopts a multi-way switching valve, the multi-way switching valve includes a first liquid inlet channel, a second liquid inlet channel, a first liquid outlet channel and a second liquid outlet channel, the first liquid inlet channel is communicated with the first liquid outlet channel, the second liquid inlet channel is communicated with the second liquid outlet channel; the first liquid inlet channel and the second liquid inlet channel are respectively connected with the outside of the two groups of column oven 4 liquid outlet side chromatographic column interfaces 14, and the first liquid outlet channel and the second liquid outlet channel are respectively connected with the liquid inlet of the liquid chromatograph detector 5 and the conductivity detector 6.

[0022] The above merely describes the preferred embodiments of the present application and is not intended to limit the present application, and any modification, equivalent replacement and improvement within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A dual liquid chromatography and ion chromatography system, characterized by, The liquid chromatograph comprises sequentially connected flow phase bottles, a liquid phase pump, a sample injector, a column oven, a detector, and a waste liquid bottle, a control valve is arranged at the connection between the column oven and the detector, the detector comprises a liquid phase detector and a conductivity detector, the liquid outlet channels of the control valve are respectively connected with the liquid inlets of the liquid phase detector and the conductivity detector, the liquid outlets of the liquid phase detector and the conductivity detector are connected to the waste liquid bottle through connecting pipes, and the data output ends of the liquid phase detector and the conductivity detector are respectively electrically connected to a multi-channel data acquisition system.

2. The dual liquid chromatography-ion chromatography system of claim 1, wherein, The liquid inlet side and the liquid outlet side of the column oven are respectively provided with two groups of chromatographic column interfaces, and the chromatographic columns of the liquid chromatograph and the ion chromatograph are respectively connected between the two groups of chromatographic column interfaces.

3. The dual liquid chromatography-ion chromatography system of claim 2, wherein, The control valve adopts a multi-way switching valve, the multi-way switching valve comprises a first liquid inlet channel, a second liquid inlet channel, a first liquid outlet channel, and a second liquid outlet channel, the first liquid inlet channel is in communication with the first liquid outlet channel, and the second liquid inlet channel is in communication with the second liquid outlet channel, the first liquid inlet channel and the second liquid inlet channel are respectively connected with the outside of the two groups of chromatographic column interfaces on the liquid outlet side of the column oven, and the first liquid outlet channel and the second liquid outlet channel are respectively connected with the liquid inlets of the liquid phase detector and the conductivity detector.

4. The dual liquid chromatography-ion chromatography system of claim 2, wherein, A multi-way valve is arranged between the sample injector and the column oven, one side of the multi-way valve is in communication with the flow phase pipeline and the sample injector, and the other side of the multi-way valve is externally connected with the chromatographic column interfaces on the liquid inlet side of the column oven through flow channel switching.

5. The dual liquid chromatography-ion chromatography system of claim 1, wherein, The liquid inlets of the liquid phase pump are connected with multiple flow phase bottles through a multi-way valve.

6. The dual liquid chromatography-ion chromatography system of claim 1, wherein, The liquid phase detector and the conductivity detector are arranged in a detection box, a liquid discharge interface is arranged on the detection box, and the liquid discharge interface is connected with the waste liquid bottle through a connecting pipe.

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