GEn nuclease reagent split charging and storing device

Abstract

The utility model discloses a GEn nuclease reagent split charging and storing device which comprises a box body, a plurality of placing partition cavities formed in the front face of the box body and a plurality of L-shaped sliding plates connected to the inner sides of the placing partition cavities in a sliding mode. A reagent rack for placing a reagent is fixed on one side, facing the interior of the placing partition cavity, of the L-shaped sliding plate; different reagents are placed in the box body with a plurality of independent placement partition cavities, and a stable and uniform low-temperature storage environment is provided for the reagents in each placement partition cavity under the cooperation of a semiconductor chilling plate, a micro water pump, a heat exchange block, a heat exchange runner, a liquid pumping pipe, a liquid feeding pipe, an air inlet, an air inlet groove and an air supply fan; the low-temperature environment required by the reagent is kept, and meanwhile, the problem of severe temperature fluctuation caused by frequent taking and placing in traditional refrigerator type preservation is also avoided, so that the preservation and use effects are improved, the reagent is convenient to subpackage and store in a classified manner, and the flexibility of reagent management is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to reagent storage technical field especially, relates to a GEn nuclease reagent subpackaging storage device. BACKGROUND

[0002] In the field of biochemistry research, nucleases as an important enzyme class are widely used in molecular biology experiments, genetic engineering, disease diagnosis and treatment and many other fields. GEn nuclease as one of the nucleases with specific enzyme activity, due to its high efficiency, strong specificity and other characteristics, plays a vital role in scientific research and clinical application.

[0003] Because the activity and stability of GEn nuclease are susceptible to environmental temperature and storage conditions, improper storage conditions may lead to reduced enzyme activity, affecting the accuracy and reliability of subsequent experimental results, and the traditional nuclease reagent storage method mostly uses refrigerator or freezer for storage, in large laboratories or medical institutions, due to the large number of reagents and large demand, frequent opening of refrigerator or freezer door will cause temperature fluctuation of the whole storage reagent, affecting the stability of the reagent. SUMMARY

[0004] The utility model overcomes the insufficient prior art, provides a GEn nuclease reagent subpackaging storage device.

[0005] To achieve the above purpose, the utility model adopts the technical scheme of a GEn nuclease reagent subpackaging storage device, comprising: a box, a plurality of placing compartments are opened in the front of the box, and a plurality of L-shaped slides are slidingly connected to the inner side of the placing compartments;

[0006] The inner side of the box around the plurality of placing compartments is provided with an equipment cavity, both sides of the interior of the placing compartment are provided with an air inlet slot, the side of the box opposite to the air inlet slot is provided with a plurality of air inlets, the inner side of the air inlet slot is provided with a blower fan, and the interior of the equipment cavity is symmetrically provided with a plurality of temperature control mechanisms;

[0007] The temperature control mechanism comprises: a semiconductor refrigeration sheet and a micro water pump fixed on the top of the equipment cavity, two heat exchange blocks for installing the refrigeration end and the heating end of the semiconductor refrigeration sheet, and a heat exchange flow channel opened in the heat exchange block;The input end of the micro water pump is fixed with a liquid suction pipe between one end of the heat exchange flow channel, and the output end of the micro water pump is fixed with a liquid delivery pipe between the other end of the heat exchange flow channel.

[0008] In a preferred embodiment of the utility model, the inside of the air inlet groove is connected to the inside of the equipment cavity, and the side of the liquid delivery pipe at the refrigeration end of the semiconductor refrigerating sheet sequentially passes through the side of a plurality of air inlet grooves.

[0009] In a preferred embodiment of the utility model, the heat exchange flow channel and the liquid delivery pipe on the side of the air inlet groove are both in a serpentine distribution, so as to improve the temperature transfer effect.

[0010] In a preferred embodiment of the utility model, the liquid delivery pipe at the heating end of the semiconductor refrigerating sheet is provided with a heat dissipation fin, one end of the heat dissipation fin penetrates through the top of the box, and the bottom of the heat dissipation fin is provided with a heat dissipation fan.

[0011] In a preferred embodiment of the utility model, the front of the box is provided with a controller for sending or receiving instructions, and the front of the L-shaped sliding plate is provided with a temperature sensor for monitoring the internal environmental temperature of the placement partition cavity; the controller is electrically connected with the temperature sensor, the semiconductor refrigerating sheet, the micro water pump, the air supply fan and the heat dissipation fan.

[0012] In a preferred embodiment of the utility model, the front of the box near the bottom is provided with a sliding cavity, the top of the sliding cavity is connected to the inside of the equipment cavity, and the inside of the sliding cavity is slidably connected with a receiving frame; the receiving frame is used for receiving condensed water generated on the surface of the liquid delivery pipe.

[0013] In a preferred embodiment of the utility model, the front of the L-shaped sliding plate and the receiving frame is both fixed with a handle.

[0014] In a preferred embodiment of the utility model, the front of the L-shaped sliding plate is fixed with a label box for placing and distinguishing reagent type labels.

[0015] In a preferred embodiment of the utility model, the bottom of the box is provided with a plurality of universal wheels for facilitating the movement of the box.

[0016] In a preferred embodiment of the utility model, the bottom of the box is provided with a plurality of support foot cups for driving a plurality of universal wheels off the ground.

[0017] The utility model solves the defects in the background art and has the following beneficial effects:

[0018] (1) The utility model provides a kind of GEn nuclease reagent subpackaging storage device, by different reagent is placed in the box body with multiple independent placement isolation cavity, under the cooperation of semiconductor refrigerating sheet, micro water pump, heat exchange block, heat exchange runner, liquid suction pipe, liquid delivery pipe, air inlet, air inlet groove and air supply fan, a stable and uniform low-temperature storage environment is provided for the reagent in each placement isolation cavity, the low-temperature environment required to maintain reagent is realized, and the temperature fluctuation problem caused by frequent taking and placing in traditional refrigerator type storage is also avoided, so as to not only improve the storage and use effect, but also facilitate the subpackaging and classified storage of reagent, improve the flexibility of reagent management.

[0019] (2) In the utility model, by installing the liquid delivery pipe on the heat-generating end of the semiconductor refrigerating sheet, when the heat-generating end of the semiconductor refrigerating sheet forms a heat exchange runner, a liquid suction pipe, a micro water pump, and a flow circulation loop from the liquid delivery pipe to the heat exchange runner, the liquid medium in the liquid delivery pipe can be cooled through the cooperation of the heat dissipation fins, and the air flow can be accelerated through the cooperation of the heat dissipation fan, effectively improving the heat dissipation efficiency of the heat-generating end of the semiconductor refrigerating sheet, ensuring that the semiconductor refrigerating sheet can work continuously and stably, and helping to improve the refrigeration effect of the refrigeration end, thereby improving the temperature control effect of the liquid medium.

[0020] (3) In the utility model, by setting a controller on the front of the box, the low-temperature storage temperature in the placement isolation cavity can be set to the controller, and through the cooperation of the controller and the temperature sensor, the power of the semiconductor refrigerating sheet can be automatically controlled according to the temperature detected by the temperature sensor, so that the temperature of the liquid medium is maintained at a suitable temperature, and the air introduced into the placement isolation cavity is ensured to reach the set temperature value, thereby achieving intelligent temperature control effect. BRIEF DESCRIPTION OF DRAWINGS

[0021] The utility model will be further described below in combination with drawings and examples;

[0022] Figure 1 is the perspective structure diagram of the preferred embodiment of the utility model;

[0023] Figure 2 is the L-shaped slide plate and receiving frame separation structure diagram of the preferred embodiment of the utility model;

[0024] Figure 3 is the overall front view half cut structure and its local enlarged view of the preferred embodiment of the utility model;

[0025] Figure 4 is the box side view partial half cut structure diagram of the preferred embodiment of the utility model;

[0026] In the figure: 1, box; 2, placed partition cavity; 21, L-shaped slide plate; 22, reagent rack; 3, equipment cavity; 4, air inlet slot; 41, air inlet; 42, air supply fan; 5, semiconductor refrigeration sheet; 51, micro water pump; 52, heat exchange block; 53, liquid suction pipe; 54, liquid supply pipe; 6, heat dissipation fin; 61, heat dissipation fan; 7, controller; 71, temperature sensor; 8, sliding cavity; 81, receiving frame; 9, handle; 10, label box; 11, universal wheel; 12, support foot cup. DETAILED DESCRIPTION

[0027] The utility model will be explained in further detail now in combination with the drawings and examples, these drawings are all simplified schematic diagram, only with schematic way shows the basic structure of the utility model, therefore it shows only the related structure of the utility model.

[0028] As Figure 1 , Figure 2 and Figure 3 Indicated, a GEn nuclease reagent sub-packaging storage device, comprising: box 1, the opening in the front of box 1 several placed partition cavity 2, and the sliding connection in the inside of several placed partition cavity 2 several L-shaped slide plate 21;L-shaped slide plate 21 towards the side fixed for placing reagent reagent rack 22 in the inside of placed partition cavity 2;Box 1 is located in the inside of several placed partition cavity 2 four around equipment cavity 3, placed partition cavity 2 both sides are equipped with air inlet slot 4, the side of box 1 is equipped with several air inlets 41 to several air inlet slot 4, the inside of air inlet slot 4 is installed air supply fan 42, the inside of equipment cavity 3 is provided with several temperature control mechanisms symmetrically;Temperature control mechanism includes: fixed in the top of equipment cavity 3 semiconductor refrigeration sheet 5 and micro water pump 51, installs the two heat exchange blocks 52 of semiconductor refrigeration sheet 5 refrigeration end and heating end, and is equipped in the inside of heat exchange block 52 heat exchange flow channel;Micro water pump 51's input end and heat exchange flow channel one end between fixed liquid suction pipe 53, micro water pump 51's output end and heat exchange flow channel another end between fixed liquid supply pipe 54.

[0029] It needs to be explained that the inner side of the air inlet groove 4 penetrates to the inside of the equipment cavity 3, and the liquid delivery pipe 54 side of the semiconductor refrigeration sheet 5 refrigeration end is sequentially through the side of several air inlet grooves 4, and the liquid medium in the liquid delivery pipe 54 and the liquid delivery pipe 54 is preferably cooling liquid; by placing different reagents in the box 1 with multiple independent placement compartments 2, and placing the reagent rack 22 on one side of the L-shaped slide plate 21 located in the placement compartment 2, by starting the semiconductor refrigeration sheet 5, and simultaneously starting the micro water pump 51, the liquid medium in the liquid delivery pipe 54, after flowing into the heat exchange flow channel in the heat exchange block 52, can exchange heat with the refrigeration end of the semiconductor refrigeration sheet 5, can make the liquid medium in the heat exchange flow channel cooling, and through the liquid delivery pipe 54 of the output end, through the side of several air inlet grooves 4, and using the air inlet fan 42 to introduce the outside air through the air inlet 41, the low-temperature liquid medium in the liquid delivery pipe 54 is used to cool the air, and then blown into each placement compartment 2, to provide a stable and uniform low-temperature storage environment for the reagent, to realize the required low-temperature environment for keeping the reagent, and to avoid the temperature fluctuation problem caused by frequent taking and placing in the traditional refrigerator type storage, so as to not only improve the storage and use effect, but also facilitate the reagent sub-packaging and classified storage, and improve the flexibility of reagent management.

[0030] As shown in Figure 3 and Figure 4 , in some embodiments, the heat exchange flow channel and the liquid delivery pipe 54 located on the side of the air inlet groove 4 are in a serpentine distribution, which is used to improve the temperature transfer effect; through the serpentine distribution of the heat exchange flow channel, the flow length of the liquid medium in the heat exchange block 52 is increased, and the heat exchange efficiency is improved; through the serpentine distribution of the liquid delivery pipe 54, the heat exchange area and time are increased, so that the temperature transfer effect is more significant, and the temperature in the placement compartment 2 can be more effectively adjusted.

[0031] As shown in Figure 1 and Figure 3 , in some embodiments, the liquid delivery pipe 54 located on the heating end of the semiconductor refrigeration sheet 5 is provided with a heat dissipation fin 6, one end of the heat dissipation fin 6 penetrates to the top of the box 1, and the bottom of the heat dissipation fin 6 is provided with a heat dissipation fan 61.

[0032] It needs to be explained that when the heating end of the semiconductor refrigeration sheet 5 forms a heat exchange flow channel, a liquid delivery pipe 54, a micro water pump 51, and a flow circulation loop of the liquid delivery pipe 54 to the heat exchange flow channel, the liquid medium in the flow circulation loop absorbs the heat of the heating end, and at the same time, the liquid medium in the liquid delivery pipe 54 is cooled by the heat dissipation fin 6 on the liquid delivery pipe 54, and the air flow is accelerated by the heat dissipation fan 61, which can effectively improve the heat dissipation efficiency of the heating end of the semiconductor refrigeration sheet 5, ensure that the semiconductor refrigeration sheet 5 can work stably and continuously, help to improve the refrigeration effect of the refrigeration end, and thus improve the temperature control effect of the liquid medium.

[0033] In some embodiments, the front of the box 1 is provided with a controller 7 for issuing or receiving instructions, and the front of the L-shaped slide plate 21 is provided with a temperature sensor 71 for monitoring the temperature inside the placement compartment 2; the controller 7 is electrically connected to the temperature sensor 71, the semiconductor refrigeration sheet 5, the micro water pump 51, the air supply fan 42 and the heat dissipation fan 61 respectively.

[0034] It should be noted that the low-temperature storage temperature inside the placement compartment 2 can be set to the controller 7, the temperature inside the placement compartment 2 is detected by the temperature sensor 71 on the L-shaped slide plate 21, and the temperature value is transmitted to the controller 7; when the temperature value does not reach the set temperature, the controller 7 can automatically control the power of the semiconductor refrigeration sheet 5, so that the temperature of the liquid medium is maintained at a suitable temperature, and the air supplied into the placement compartment 2 ensures that the temperature reaches the set temperature value, so that it can achieve the effect of intelligent temperature control.

[0035] It can be understood that the control circuit of the controller 7 can be realized by simple programming by those skilled in the art, which belongs to the common knowledge in the art, and the present application file mainly protects mechanical devices, so the control mode and circuit connection will not be explained in detail, and will not be described in detail here.

[0036] In some embodiments, the front of the box 1 near the bottom is provided with a sliding cavity 8, the top of the sliding cavity 8 is through with the inside of the equipment cavity 3, and the inside of the sliding cavity 8 is slidably connected with a receiving frame 81, and the receiving frame 81 is used for receiving the condensed water generated on the surface of the liquid supply pipe 54.

[0037] It should be noted that when the semiconductor refrigeration sheet 5 works, the condensed water generated on the surface of the liquid supply pipe 54 of the refrigeration end can drop into the inside of the receiving frame 81 in the sliding cavity 8 from the inside of the equipment wall, so as to facilitate the collection of the generated condensed water, and the sliding receiving frame 81 can be conveniently taken out and cleaned.

[0038] In some embodiments, the front of the L-shaped slide plate 21 and the receiving frame 81 is fixed with a handle 9; through the setting of the handle 9, the user can operate the L-shaped slide plate 21 and the receiving frame 81, so that the extraction and push-in of the reagent rack 22 and the taking out and putting back of the receiving frame 81 are more convenient.

[0039] In some embodiments, the front of the L-shaped slide plate 21 is fixed with a label box 10 for placing labels distinguishing reagent types; the label box 10 is used for placing labels distinguishing reagent types, which facilitates the user to quickly identify the types of reagents, avoids confusion, and improves the efficiency and accuracy of reagent management.

[0040] In some embodiments, the bottom of the box 1 is provided with a plurality of universal wheels 11 for facilitating the movement of the box 1; the provision of the plurality of universal wheels 11 facilitates the movement of the box 1 and improves the flexibility of the box 1.

[0041] In some embodiments, the bottom of the box 1 is provided with a plurality of support foot cups 12 for lifting the plurality of universal wheels 11 off the ground; when the box 1 is moved to a fixed position, the support foot cups 12 can lift the plurality of universal wheels 11 off the ground, support the bottom of the box 1, and increase the stability of the device.

[0042] In use, the box 1, the placement compartment 2, and the L-shaped sliding plate 21 structure are used to place the reagent on the reagent rack 22 and push it into the respective independent placement compartment 2, start the semiconductor refrigeration sheet 5 and the micro water pump 51, the cooling liquid circulates under the action of the micro water pump 51, first flows through the refrigeration end of the semiconductor refrigeration sheet 5 for cooling, and then is arranged around the air inlet groove 4 through the liquid delivery pipe 54 in a serpentine distribution to enhance the heat exchange efficiency. At the same time, the air supply fan 42 introduces external air from the air inlet 41, and the air is cooled by the low-temperature cooling liquid circulating in the liquid delivery pipe 54 and blown into the placement compartment 2 to provide a stable and uniform low-temperature storage environment for the reagent. At the same time, the heating end of the semiconductor refrigeration sheet 5 absorbs the heat of the heating end through the liquid medium in the liquid suction pipe 53 and the liquid delivery pipe 54, and accelerates heat dissipation through the heat dissipation fins 6 and the heat dissipation fan 61 to ensure stable operation of the semiconductor refrigeration sheet 5. The temperature sensor 71 monitors the temperature in the placement compartment 2 and feeds back data to the controller 7, and the controller 7 automatically adjusts the working state of the semiconductor refrigeration sheet 5 and the air supply fan 42 according to the preset temperature to realize intelligent temperature control. In addition, the condensed water drops from the inside of the equipment cavity 3 into the receiving frame 81 of the sliding cavity 8 for easy collection and cleaning, and the handles 9 on the L-shaped sliding plate 21 and the receiving frame 81 are designed for easy operation and management by the user.

[0043] The above is based on the ideal embodiment of the utility model, and for those skilled in the art, the utility model is obviously not limited to the details of the above exemplary embodiments, and can be realized in other specific forms without departing from the spirit or basic characteristics of the utility model. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting, and the scope of the utility model is defined by the appended claims rather than the above description, and therefore all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the utility model. Any reference signs in the claims should not be considered as limiting the claims involved.

[0044] Furthermore, it should be understood that although the specification is described in terms of embodiments, not every embodiment includes every feature described. The specification can include implicit combinations of explicitly mentioned features and / or explicit combinations of implicitely mentioned features. Each embodiment depends on the explicit combinations of features and / or the implicit combinations of features made specifically within that embodiment, and each such embodiment can be combined with every other such embodiment to create further embodiments.

Claims

1. A GEn nuclease reagent aliquot storage device, comprising: Include: The box (1) is provided with a plurality of placing compartments (2) on the front of the box (1), and a plurality of L-shaped sliding plates (21) are slidably connected to the inner side of the plurality of placing compartments (2); the side of the L-shaped sliding plate (21) facing the inside of the placing compartment (2) is fixed with a reagent rack (22) for placing reagents; The inner side of the box (1) around the plurality of placing compartments (2) is provided with an equipment cavity (3), both sides of the inside of the placing compartment (2) are provided with an air inlet groove (4), the side of the box (1) opposite to the air inlet groove (4) is provided with a plurality of air inlets (41), the inner side of the air inlet groove (4) is provided with a supply fan (42), and the inside of the equipment cavity (3) is symmetrically provided with a plurality of temperature control mechanisms; The temperature control mechanism comprises a semiconductor refrigeration sheet (5) and a micro water pump (51) fixed on the top of the equipment cavity (3), two heat exchange blocks (52) installed on the refrigeration end and heating end of the semiconductor refrigeration sheet (5), and a heat exchange flow channel provided in the heat exchange block (52); the input end of the micro water pump (51) is fixed with a liquid suction pipe (53) between one end of the heat exchange flow channel, and the output end of the micro water pump (51) is fixed with a liquid supply pipe (54) between the other end of the heat exchange flow channel.

2. The device for storing GEn nuclease reagent in small quantities according to claim 1, characterized in that: The inner side of the air inlet groove (4) penetrates to the inside of the equipment cavity (3), and the side of the liquid supply pipe (54) located at the refrigeration end of the semiconductor refrigeration sheet (5) sequentially passes through one side of a plurality of air inlet grooves (4).

3. The device for storing GEn nuclease reagent in small quantities according to claim 1, characterized in that: The heat exchange flow channel and the liquid supply pipe (54) located on one side of the air inlet groove (4) are both in a serpentine distribution, which is used to improve the temperature transfer effect.

4. The device for storing GEn nuclease reagent in small quantities according to claim 1, characterized in that: The liquid supply pipe (54) located at the heating end of the semiconductor refrigeration sheet (5) is provided with a heat dissipation fin (6), one end of the heat dissipation fin (6) penetrates to the top of the box (1), and the bottom of the heat dissipation fin (6) is provided with a heat dissipation fan (61).

5. The device for storing GEn nuclease reagent in small quantities according to claim 4, characterized in that: The front of the box (1) is provided with a controller (7) for issuing or receiving instructions, and the front of the L-shaped sliding plate (21) is provided with a temperature sensor (71) for monitoring the temperature of the inside of the placing compartment (2); the controller (7) is electrically connected with the temperature sensor (71), the semiconductor refrigeration sheet (5), the micro water pump (51), the supply fan (42) and the heat dissipation fan (61) respectively.

6. The device for storing GEn nuclease reagent in small quantities according to claim 1, characterized in that: The front of the box (1) close to the bottom is provided with a sliding cavity (8), the top of the sliding cavity (8) penetrates to the inside of the equipment cavity (3), the inner side of the sliding cavity (8) is slidably connected with a receiving frame (81), and the receiving frame (81) is used to receive the condensed water generated on the surface of the liquid supply pipe (54).

7. The device for storing GEn nuclease reagent in small portions according to claim 6, characterized in that: The front of the L-shaped sliding plate (21) and the receiving frame (81) is fixed with a handle (9).

8. The device for storing GEn nuclease reagent in small portions according to claim 1, characterized in that: The front of the L-shaped sliding plate (21) is fixed with a label box (10) for placing labels distinguishing reagent types.

9. The device for storing GEn nuclease reagent in small portions according to claim 1, characterized in that: The bottom of the box (1) is provided with a plurality of universal wheels (11) for facilitating the movement of the box (1).

10. The device for storing GEn nuclease reagent in small portions according to claim 9, characterized in that: The bottom of the box (1) is provided with several supporting foot cups (12) for driving several universal wheels (11) off the ground.

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