Sterile preparation liquid preparation device
By incorporating a circulation unit and a stirring assembly into the aseptic preparation preparation device, and utilizing an inclined nozzle to subject the powder to high-speed impact, the problem of powder clumping was solved, enabling rapid mixing of the liquid and powder and improving production efficiency.
Patent Information
- Application Number
- CN202520094054.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-15
- Publication Date
- 2026-01-06
- Estimated Expiration
- 2035-01-15
AI Technical Summary
During the preparation of sterile drug solutions, powders are prone to clumping, which prolongs the mixing time and affects production efficiency.
A sterile preparation preparation device was designed, comprising a preparation tank, an inlet, a stirring assembly, and an infusion assembly. The drug liquid raw material is circulated to the bottom of the inlet using a circulation unit, and the powder is impacted at high speed by an inclined nozzle. Combined with the stirring blades of the stirring assembly, the drug liquid and powder are rapidly mixed.
It effectively avoids powder clumping, improves mixing efficiency, and shortens solution preparation time.
Smart Images

Figure CN223760882U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of liquid preparation device technology, specifically a sterile preparation liquid preparation device. Background Technology
[0002] Sterile preparations refer to a class of pharmaceutical preparations that are prepared in a sterile environment using aseptic methods or techniques and do not contain any living microorganisms. Currently, the methods for producing sterile preparations in the pharmaceutical industry generally include the following process steps: transporting containers to a sterile room, cleaning containers, sterilizing containers, transporting containers under sterile conditions, preparing sterile drug solutions, preparing sterile drug solutions for filling, sterile filtration of drug solutions, transporting drug solutions under sterile conditions, supplying, cleaning and sterilizing caps, sealing caps under sterile conditions, and outputting from the sterile room.
[0003] When preparing sterile drug solutions, there is a situation where powder and drug solution are mixed together. When the powder enters the mixing tank, it is easy for it to clump together, which makes it take longer to complete the preparation operation. Based on this, a sterile preparation mixing device is provided. Utility Model Content
[0004] The purpose of this invention is to provide a sterile preparation solution device in order to solve the problems mentioned above.
[0005] To achieve the above objectives, the present invention provides the following technical solution: a sterile preparation solution preparation device, comprising a solution preparation assembly consisting of a solution preparation tank and an inlet, and a stirring assembly. The inlet is fixed to the top of the solution preparation tank and extends into the interior of the solution preparation tank. The stirring assembly is installed in the middle of the top of the solution preparation tank and extends into the interior of the solution preparation tank for stirring and mixing the drug solution inside the solution preparation tank. An infusion assembly extending into the inlet is provided on the outside of the solution preparation tank. The infusion assembly includes a draining unit and a circulation unit.
[0006] The drainage unit is used to transport the prepared medicine solution to the next process.
[0007] The circulation unit is used to circulate and transport the liquid raw materials to the bottom opening of the feed inlet, and to perform high-speed impact operation on the powder entering the liquid preparation tank through the feed inlet.
[0008] As a further embodiment of this utility model: the drainage unit includes a delivery pump, a connecting pipe, a three-way solenoid valve, and a delivery pipe;
[0009] The delivery pump is located at the bottom of the liquid preparation tank, and the input end of the delivery pump is connected to the inner cavity of the liquid preparation tank through a pipe.
[0010] The output end of the delivery pump is connected to the input end of the three-way solenoid valve through a connecting pipe. The infusion pipe is fixed to one output end of the three-way solenoid valve. The delivery pump is used to deliver the prepared medicine solution inside the preparation tank to the infusion pipe.
[0011] As a further embodiment of this utility model: the circulation unit includes a return pipe, an annular pipe, a two-way solenoid valve, and an inclined nozzle;
[0012] The return pipe is fixed to the other delivery end of the three-way solenoid valve, the annular pipe is distributed on the top of the outside of the liquid preparation tank, and the top of the return pipe is connected to the annular pipe.
[0013] The inclined nozzle is connected to the annular pipe via a two-way solenoid valve and extends through the liquid preparation tank to the inside of the feed inlet. The conveying channel, consisting of a conveying pump, connecting pipe, three-way solenoid valve, return pipe, annular pipe, two-way solenoid valve, and inclined nozzle, is used to convey the pharmaceutical raw materials to the inside of the feed inlet and to perform high-speed impact operation on the powder entering the liquid preparation tank through the feed inlet.
[0014] As a further improvement of this utility model: multiple feed inlets are provided, and the multiple feed inlets are evenly distributed along the circumferential direction;
[0015] The number and position of the two-way solenoid valves and the inclined nozzles correspond one-to-one with the number and position of the feed inlets.
[0016] As a further improvement of this utility model, the circulation unit also includes a rotating shaft and feeding blades;
[0017] The material feeding blades are provided in multiple ways. The multiple material feeding blades are circumferentially fixed to the outside of the rotating shaft. The material feeding blades are rotatably installed on the bottom inner side of the feed inlet through the rotating shaft. The end of the inclined nozzle away from the two-way solenoid valve is inclined towards the distribution area of the material feeding blades.
[0018] The high-speed water flow from the inclined nozzle impacts the feeding blades, causing them to rotate and thus enabling the small-scale feeding operation of the powder.
[0019] As a further embodiment of this utility model: the stirring assembly includes a drive motor, a stirring shaft, and stirring blades;
[0020] The drive motor is installed at the top center of the liquid preparation tank, the stirring shaft is fixed to the output end of the drive motor and extends into the interior of the liquid preparation tank, and the stirring blades are fixed to the bottom of the stirring shaft.
[0021] Compared with the prior art, the beneficial effects of this utility model are:
[0022] By setting up an infusion assembly with a circulation unit, the liquid raw material can be fed into the inclined nozzle and impacted into the feed inlet, achieving a high impact on the powder raw material. This not only achieves preliminary mixing of the liquid and powder raw materials, but also effectively avoids the clumping of the powder raw materials, further improving the mixing efficiency. Attached Figure Description
[0023] Figure 1 This is a schematic diagram of the structure of this utility model;
[0024] Figure 2 This is a structural cross-sectional view of the liquid preparation tank and infusion assembly of this utility model;
[0025] Figure 3 This is a cross-sectional view of the feed inlet and inclined nozzle of this utility model.
[0026] In the diagram: 1. Liquid preparation assembly; 101. Liquid preparation tank; 102. Feed inlet; 2. Stirring assembly; 201. Drive motor; 202. Stirring shaft; 203. Stirring blades; 3. Liquid delivery assembly; 301. Delivery pump; 302. Connecting pipe; 303. Three-way solenoid valve; 304. Delivery pipe; 305. Return pipe; 306. Circular pipe; 307. Two-way solenoid valve; 308. Inclined nozzle; 309. Rotating shaft; 310. Feeding blades. Detailed Implementation
[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0028] Please see Figures 1-3 In this embodiment of the present invention, a sterile preparation solution preparation device includes a solution preparation component 1 consisting of a solution preparation tank 101 and a feed inlet 102, and a stirring component 2. The feed inlet 102 is fixed to the top of the solution preparation tank 101 and extends into the interior of the solution preparation tank 101. The stirring component 2 is installed in the middle of the top of the solution preparation tank 101 and extends into the interior of the solution preparation tank 101 for stirring and mixing the drug solution inside the solution preparation tank 101. An infusion component 3 extending into the feed inlet 102 is provided on the outside of the solution preparation tank 101. The infusion component 3 includes a draining unit and a circulation unit.
[0029] The drainage unit is used to transport the prepared medicine solution to the next process.
[0030] The circulation unit is used to circulate and transport the raw materials of the medicine to the bottom opening of the feed inlet 102, and to perform high-speed impact operation on the powder that enters the liquid preparation tank 101 through the feed inlet 102.
[0031] The drainage unit includes a transfer pump 301, a connecting pipe 302, a three-way solenoid valve 303, and a delivery pipe 304;
[0032] The transfer pump 301 is located at the bottom of the liquid preparation tank 101, and the input end of the transfer pump 301 is connected to the inner cavity of the liquid preparation tank 101 through a pipe.
[0033] The output end of the delivery pump 301 is connected to the input end of the three-way solenoid valve 303 through the connecting pipe 302. The infusion pipe 304 is fixed to one output end of the three-way solenoid valve 303. The delivery pump 301 is used to deliver the prepared medicine solution inside the preparation tank 101 to the infusion pipe 304.
[0034] The circulation unit includes a return pipe 305, an annular pipe 306, a two-way solenoid valve 307, and an inclined nozzle 308;
[0035] The return pipe 305 is fixed to the other delivery end of the three-way solenoid valve 303, and the annular pipe 306 is distributed on the top of the outside of the liquid preparation tank 101. The top of the return pipe 305 is connected to the annular pipe 306.
[0036] The inclined nozzle 308 is connected to the annular pipe 306 through the two-way solenoid valve 307 and passes through the liquid preparation tank 101 to the inside of the feed inlet 102. The conveying channel composed of the conveying pump 301, connecting pipe 302, three-way solenoid valve 303, return pipe 305, annular pipe 306, two-way solenoid valve 307, and inclined nozzle 308 is used to convey the raw materials of the medicine liquid to the inside of the feed inlet 102, and to perform high-speed impact operation on the powder that enters the liquid preparation tank 101 through the feed inlet 102.
[0037] Multiple feed inlets 102 are provided, and the multiple feed inlets 102 are evenly distributed along the circumference;
[0038] The number and position of the two-way solenoid valves 307 and the inclined nozzles 308 correspond one-to-one with the number and position of the feed inlets 102.
[0039] The stirring assembly 2 includes a drive motor 201, a stirring shaft 202, and stirring blades 203;
[0040] The drive motor 201 is installed at the top center of the liquid preparation tank 101, the stirring shaft 202 is fixed to the output end of the drive motor 201 and extends into the interior of the liquid preparation tank 101, and the stirring blade 203 is fixed to the bottom of the stirring shaft 202.
[0041] In this embodiment, the operating principle of this solution preparation device for aseptic preparation is as follows:
[0042] Multiple feed inlets 102 are connected to the conveying pipes of each liquid preparation raw material, and then the liquid raw material is first conveyed to the inside of the liquid preparation tank 101;
[0043] Afterwards, the powder raw material is transported to the liquid preparation tank 101. During this process, the delivery pump 301 is started simultaneously, and the three-way solenoid valve 303 is activated to connect the connecting pipe 302 and the return pipe 305. The delivery pump 301 draws the liquid raw material from the liquid preparation tank 101 and transports it to the annular pipe 306 through the pipeline composed of the connecting pipe 302, the three-way solenoid valve 303, and the return pipe 305. At this time, the two-way solenoid valve 107 corresponding to the powder raw material inlet 102 is activated simultaneously. The liquid raw material inside the annular pipe 306 will enter the inlet 102 through the opened two-way solenoid valve 107 and the inclined nozzle 108, achieving a high impact on the powder raw material and achieving preliminary mixing of the liquid raw material and powder raw material. The preliminarily mixed raw material falls into the liquid preparation tank 101. This structure can effectively avoid the clumping of the powder raw material.
[0044] At the same time, the drive motor 201 is started, and the drive motor 201 drives the stirring shaft 202 and the stirring blade 203 to rotate at high speed, so as to achieve full mixing of the medicine liquid;
[0045] Once the medicine solution in the mixing tank 101 is completely mixed, the three-way solenoid valve 303 is controlled to connect the connecting pipe 302 and the infusion pipe 304. At this time, the delivery pump 301 is started, and the mixed medicine solution can be transported to the next process through the pipeline composed of the connecting pipe 302, the three-way solenoid valve 303, and the infusion pipe 304.
[0046] Please refer to this carefully. Figure 3 The circulation unit also includes a rotating shaft 309 and a feeding blade 310;
[0047] Multiple material feeding blades 310 are provided. Multiple material feeding blades 310 are circumferentially fixed to the outside of the rotating shaft 309. The material feeding blades 310 are rotatably installed on the inner bottom of the feed inlet 102 through the rotating shaft 309. The end of the inclined nozzle 308 away from the two-way solenoid valve 307 is inclined towards the distribution area of the material feeding blades 310.
[0048] The high-speed water flow from the inclined nozzle 308 impacts the feeding blade 310 to make the feeding blade 310 rotate, thereby realizing the small-powder feeding operation.
[0049] In this embodiment: the liquid medicine material sprayed at high speed through the inclined nozzle 308 can impact the feeding blades 310, causing multiple feeding blades 310 to rotate around the rotating shaft 309. In this way, not only can the powder material inside the feed inlet 102 be pushed downward to avoid powder blockage, but the powder material can also be better contacted with the liquid medicine material.
[0050] It should also be noted that the width of the feeding blade 310 is smaller than the diameter of the feed inlet 102, that is, the two sides of the feeding blade 310 do not come into contact with the feed inlet 102, which ensures that the feeding blade 310 rotates smoothly. The feeding blade 310 mainly plays the role of moving the powder raw material and will not obstruct the feeding of the liquid raw material.
[0051] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.
Claims
1. A sterile preparation solution preparation device, comprising a solution preparation assembly (1) composed of a solution preparation tank (101) and a feed inlet (102), the feed inlet (102) being fixed to the top of the solution preparation tank (101) and penetrating into the inside of the solution preparation tank (101), and a stirring assembly (2) installed at the middle of the top of the solution preparation tank (101) and extending into the inside of the solution preparation tank (101) for stirring and mixing the liquid medicine in the inside of the solution preparation tank (101), characterized in that, The outside of the liquid preparation tank (101) is provided with a liquid delivery assembly (3) extending to the inside of the feed port (102), the liquid delivery assembly (3) comprising a liquid discharge unit and a circulating unit; The liquid discharge unit is used for delivering the prepared liquid medicine to the next process; The circulating unit is used for circulating the liquid medicine raw material to the opening at the bottom of the feed port (102) to perform high-speed impact operation on the powder entering the inside of the liquid preparation tank (101) through the feed port (102).
2. The sterile preparation solution dispensing device according to claim 1, wherein The liquid discharge unit comprises a delivery pump (301), a connecting pipe (302), a three-way electromagnetic valve (303), and a liquid delivery pipe (304); The delivery pump (301) is arranged at the bottom of the liquid preparation tank (101), and the input end of the delivery pump (301) is communicated with the inner cavity of the liquid preparation tank (101) through a pipeline; The output end of the delivery pump (301) is communicated with the input end of the three-way electromagnetic valve (303) through the connecting pipe (302), and the liquid delivery pipe (304) is fixed to one output end of the three-way electromagnetic valve (303), and the delivery pump (301) is used for delivering the prepared liquid medicine in the liquid preparation tank (101) to the liquid delivery pipe (304).
3. The sterile preparation solution dispensing device according to claim 2, wherein The circulating unit comprises a return pipe (305), an annular pipe (306), a two-way electromagnetic valve (307), and an inclined spray pipe (308); The return pipe (305) is fixed to the other delivery end of the three-way electromagnetic valve (303), the annular pipe (306) is arranged at the top of the outside of the liquid preparation tank (101), and the top of the return pipe (305) is connected and communicated with the annular pipe (306); The inclined spray pipe (308) is communicated with the annular pipe (306) through the two-way electromagnetic valve (307) and penetrates the liquid preparation tank (101) to the inside of the feed port (102), and the delivery channel composed of the delivery pump (301), the connecting pipe (302), the three-way electromagnetic valve (303), the return pipe (305), the annular pipe (306), the two-way electromagnetic valve (307), and the inclined spray pipe (308) is used for delivering the liquid medicine raw material to the inside of the feed port (102) to perform high-speed impact operation on the powder entering the inside of the liquid preparation tank (101) through the feed port (102).
4. The sterile preparation solution dispensing device according to claim 3, wherein A plurality of feed ports (102) are arranged, and the plurality of feed ports (102) are uniformly distributed in the circumferential direction; The number and position of the two-way electromagnetic valve (307) and the inclined spray pipe (308) correspond to the number and position of the feed port (102) one by one.
5. The sterile preparation solution dispensing device according to claim 3, wherein The circulating unit further comprises a rotating shaft (309) and a stirring blade (310); A plurality of stirring blades (310) are arranged, and the plurality of stirring blades (310) are circumferentially fixed to the outside of the rotating shaft (309), the stirring blade (310) is rotatably arranged at the inside bottom of the feed port (102) through the rotating shaft (309), and the end of the inclined spray pipe (308) away from the two-way electromagnetic valve (307) is inclined towards the distribution area of the stirring blade (310); The high-speed water flow flowing out of the inclined spray pipe (308) impacts the stirring blade (310) to rotate the stirring blade (310), thereby achieving the small material stirring operation of the powder.
6. The aseptic preparation solution dispensing device according to claim 1, wherein The stirring assembly (2) comprises a driving motor (201), a stirring shaft (202) and stirring blades (203); The driving motor (201) is installed at the middle part of the top of the liquid preparation tank (101), the stirring shaft (202) is fixed to the output end of the driving motor (201) and penetrates into the inside of the liquid preparation tank (101), and the stirring blades (203) are fixed to the bottom of the stirring shaft (202).