Reaction kettle for ursodesoxycholic acid production

Abstract

The utility model relates to the technical field of reaction kettles, and discloses a reaction kettle for ursodesoxycholic acid production, which comprises supporting legs, the upper surfaces of the supporting legs are fixedly connected with a reaction container, the upper surface of the reaction container is fixedly connected with a feed pipe, the inner wall of the feed pipe is provided with an adjusting assembly, the adjusting assembly comprises a top cover, and the top cover is fixedly connected with the reaction container. The top cover is arranged on the upper surface of the feeding pipe, the upper surface of the top cover is fixedly connected with a handle, the outer wall of the feeding pipe is fixedly connected with a motor, the output end of the motor is rotatably connected with a turnover disc, one end of the turnover disc is fixedly connected with a first connecting shaft, and the inner wall of the feeding pipe is slidably connected with a baffle. The outer wall of the feeding pipe is fixedly connected with an air cylinder. According to the ursodesoxycholic acid discharging device, the discharging speed can be controlled, meanwhile, the motor is started, the overturning disc is driven to rotate, raw materials are stirred for the first time, the discharging speed is more uniform, and therefore the purity and the quality stability of ursodesoxycholic acid products are improved.

Description

Technical Field

[0001] This utility model relates to the field of reaction vessel technology, and in particular to a reaction vessel for the production of ursodeoxycholic acid. Background Technology

[0002] Ursodeoxycholic acid is an important pharmaceutical ingredient, and its production process places extremely high demands on the performance of the reaction vessel. The reaction vessel plays a crucial role in the production of ursodeoxycholic acid, requiring not only precise control of the input of various raw materials but also the provision of a suitable environment for the reaction. Its performance directly affects the quality and production efficiency of ursodeoxycholic acid products.

[0003] Currently, in the existing technology of reactors for ursodeoxycholic acid production, the feeding process usually adopts a relatively simple gravity feeding method, relying on the material's own gravity to flow from the storage container into the reactor through the pipeline. Although this method is simple in structure, it lacks effective means to control the feeding speed. It is mainly achieved by manually adjusting the size of the opening at the bottom of the storage container. However, this adjustment method is not precise enough and it is difficult to adjust it quickly in real time according to the reaction requirements.

[0004] However, the simple feeding and stirring method in the existing technology makes it difficult to ensure uniform feeding speed during the production of ursodeoxycholic acid. Uneven feeding speed will lead to inconsistent distribution of raw materials in the reactor, which will affect the reaction and ultimately make it difficult to achieve the ideal purity and quality stability of the product, making it difficult to meet the increasingly stringent pharmaceutical production standards. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a reaction vessel for the production of ursodeoxycholic acid, aiming to improve the problem that existing reaction vessels cannot guarantee a uniform feeding speed. Uneven feeding speed leads to inconsistent distribution of raw materials in the reaction vessel, which in turn affects the reaction process and ultimately makes it difficult to achieve the ideal purity and quality stability of the product, thus failing to meet increasingly stringent pharmaceutical production standards.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a reaction vessel for the production of ursodeoxycholic acid, comprising a support leg, a reaction vessel fixedly connected to the upper surface of the support leg, a feed pipe fixedly connected to the upper surface of the reaction vessel, and an adjustment component provided on the inner wall of the feed pipe;

[0007] The adjustment assembly includes a top cover, which is disposed on the upper surface of the feed pipe. A handle is fixedly connected to the upper surface of the top cover. A motor is fixedly connected to the outer wall of the feed pipe. A rotating disk is rotatably connected to the output end of the motor. A connecting shaft is fixedly connected to one end of the rotating disk. A baffle is slidably connected to the inner wall of the feed pipe. A cylinder is fixedly connected to the outer wall of the feed pipe. A connecting rod is fixedly connected to the output end of the cylinder. The upper surface of the connecting rod is fixedly connected to the lower surface of the baffle.

[0008] Furthermore, a sliding rod is fixedly connected to the inner wall of the reaction vessel, a scraper is slidably connected to the outer wall of the sliding rod, a threaded rod is threadedly connected to the inner wall of the scraper, a knob is fixedly connected to one end of the threaded rod, a nozzle is fixedly connected to the inner wall of the reaction vessel, and a water pipe is fixedly connected to one end of the nozzle.

[0009] Furthermore, a worm gear is fixedly connected to the outer wall of the connecting shaft, a worm wheel is meshed with the outer wall of the worm gear, a stirring rod is fixedly connected to the outer wall of the worm wheel, and stirring blades are fixedly connected to the outer wall of the stirring rod.

[0010] Furthermore, the outer wall of the baffle is slidably connected to the inner wall of the feed pipe, and the baffle is used to control the opening and closing of the feed pipe.

[0011] Furthermore, the outer wall of the scraper is slidably connected to the inner wall of the reaction vessel, and the scraper is used to scrape material from the inner wall of the reaction vessel.

[0012] Furthermore, the threaded rod is externally rotatably connected inside the reaction vessel, and the threaded rod is used to drive the scraper to move.

[0013] Furthermore, the outer wall of the stirring rod is rotatably connected to the inner wall of the reaction vessel, and the stirring rod is used to drive the stirring blades to rotate.

[0014] Furthermore, the outer wall of the tilting disc is rotatably connected to the inner wall of the feed pipe, and the tilting disc is used to prevent the feed pipe from becoming blocked.

[0015] This utility model has the following beneficial effects:

[0016] 1. In this utility model, the cylinder pushes the connecting rod to move when the feeding speed needs to be adjusted, thereby moving the baffle and controlling the feeding speed. At the same time, the motor starts and drives the rotating disc to rotate, which stirs the raw material for the first time, making the feeding speed more uniform and thus improving the purity and quality stability of the ursodeoxycholic acid product.

[0017] 2. In this utility model, by using the knob, when it is necessary to clean the reaction vessel, turning the knob will drive the threaded rod to rotate, causing the scraper to move up and down along the slide rod, thereby cleaning the inner wall of the reaction vessel and effectively preventing residual materials from affecting the next operation. Attached Figure Description

[0018] Figure 1 This is a three-dimensional structural diagram of a reaction vessel for the production of ursodeoxycholic acid according to the present invention.

[0019] Figure 2 A schematic diagram of the tilting plate of a reaction vessel for the production of ursodeoxycholic acid proposed in this utility model;

[0020] Figure 3 This is a schematic diagram of the scraper of a reaction vessel for the production of ursodeoxycholic acid according to this utility model.

[0021] Legend:

[0022] 1. Support leg; 2. Reaction vessel; 3. Feed pipe; 4. Nozzle; 5. Handle; 6. Top cover; 7. Baffle; 8. Motor; 9. Tilting disc; 10. Connecting shaft one; 11. Worm gear; 12. Worm wheel; 13. Cylinder; 14. Connecting rod; 15. Stirring rod; 16. Stirring blade; 17. Slide rod; 18. Scraper; 19. Threaded rod; 20. Water pipe; 21. Knob. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Reference Figure 1 - Figure 3 An embodiment of this utility model provides a reaction vessel for the production of ursodeoxycholic acid, comprising a support leg 1, a reaction vessel 2 fixedly connected to the upper surface of the support leg 1, a feed pipe 3 fixedly connected to the upper surface of the reaction vessel 2, an adjustment component provided on the inner wall of the feed pipe 3, the adjustment component including a top cover 6, the top cover 6 being disposed on the upper surface of the feed pipe 3, a handle 5 fixedly connected to the upper surface of the top cover 6, a motor 8 fixedly connected to the outer wall of the feed pipe 3, a rotating disk 9 rotatably connected to the output end of the motor 8, a connecting shaft 10 fixedly connected to one end of the rotating disk 9, a baffle 7 slidably connected to the inner wall of the feed pipe 3, a cylinder 13 fixedly connected to the outer wall of the feed pipe 3, a connecting rod 14 fixedly connected to the output end of the cylinder 13, and the upper surface of the connecting rod 14 fixedly connected to the lower surface of the baffle 7.

[0025] Specifically, support leg 1 primarily supports the entire reactor structure, ensuring the stability and safety of the reactor during operation. Reaction vessel 2 is fixedly connected to the upper surface of support leg 1. Reaction vessel 2 is the main site for the ursodeoxycholic acid production reaction. Feed pipe 3 is fixedly connected to the upper surface of reaction vessel 2, serving as the channel for raw materials to enter the reactor 2. A top cover 6 is located on the upper surface of feed pipe 3, sealing and protecting the upper part of feed pipe 3 to prevent impurities from entering. It also facilitates inspection and maintenance. A handle 5 is fixedly connected to the upper surface of top cover 6, allowing operators to open or close the top cover 6 for operation or inspection inside feed pipe 3. A motor 8 is fixedly connected to the outer wall of feed pipe 3, providing power for the subsequent rotation of tilting disc 9, ensuring its continuous and stable operation. The output end of motor 8 is rotatably connected to tilting disc 9. One end of the rotating disc 9 is fixedly connected to a connecting shaft 10. The rotating disc 9 rotates under the drive of the motor 8. Its function is to prevent the feed pipe 3 from being blocked. By rotating itself, it can avoid the accumulation and blockage of raw materials in the feed pipe 3, ensuring the smooth conveying of raw materials. A baffle 7 is slidably connected to the inner wall of the feed pipe 3, and a cylinder 13 is fixedly connected to the outer wall of the feed pipe 3. A connecting rod 14 is fixedly connected to the output end of the cylinder 13. The upper surface of the connecting rod 14 is fixedly connected to the lower surface of the baffle 7. The cylinder 13 is a power component. Its output end pushes the baffle 7 to slide on the inner wall of the feed pipe 3 through the connecting rod 14. When it is necessary to adjust the feeding speed, the cylinder 13 can precisely control the stroke of the output end, thereby driving the baffle 7 to move, thereby achieving precise control of the opening and closing degree of the feed pipe 3, and achieving the purpose of controlling the feeding speed. At the same time, in conjunction with the action of the motor 8, it can achieve more precise and flexible adjustment of the feeding speed, which helps to improve the purity and quality stability of ursodeoxycholic acid products.

[0026] Reference Figure 1 - Figure 3 A slide rod 17 is fixedly connected to the inner wall of the reaction vessel 2. A scraper 18 is slidably connected to the outer wall of the slide rod 17. A threaded rod 19 is threadedly connected to the inner wall of the scraper 18. A knob 21 is fixedly connected to one end of the threaded rod 19. A nozzle 4 is fixedly connected to the inner wall of the reaction vessel 2. A water pipe 20 is fixedly connected to one end of the nozzle 4. A worm gear 11 is fixedly connected to the outer wall of the connecting shaft 10. A worm wheel 12 is meshed with the outer wall of the worm gear 11. A stirring rod 15 is fixedly connected to the outer wall of the worm wheel 12. A stirring blade 16 is fixedly connected to the outer wall of the stirring rod 15.

[0027] Specifically, a slide rod 17 is fixedly connected to the inner wall of the reaction vessel 2. The slide rod 17 provides guidance and support for the up-and-down movement of the scraper 18, ensuring that the scraper 18 will not deviate or shake during movement, making the movement of the scraper 18 more stable. The scraper 18 is slidably connected to the outer wall of the slide rod 17, and a threaded rod 19 is threadedly connected to the inner wall of the scraper 18. The function of the scraper 18 is to effectively scrape off the residual material on the inner wall of the reaction vessel 2 when cleaning is required, preventing the residual material from affecting the next production process. A knob 21 is fixedly connected to one end of the threaded rod 19. The threaded rod 19 is externally rotatably connected to the inside of the reaction vessel 2. When the knob 21 is turned, the threaded rod 19 will rotate accordingly. Due to the threaded connection between the scraper 18 and the threaded rod 19, the scraper 18 moves along the slide rod 17. The screw rod 19 moves downwards to clean different positions on the inner wall of the reaction vessel 2. The screw rod 19 drives the scraper 18 to move. A nozzle 4 is fixedly connected to the inner wall of the reaction vessel 2. A water pipe 20 is fixedly connected to one end of the nozzle 4. The nozzle 4 can spray cleaning liquid or other liquid into the reaction vessel 2 through the water pipe 20. With the scraping of the scraper 18, the inner wall of the reaction vessel 2 can be cleaned more thoroughly. A worm gear 11 is fixedly connected to the outer wall of the connecting shaft 10. A worm wheel 12 is meshed with the outer wall of the worm gear 11. A stirring rod 15 is fixedly connected to the outer wall of the worm wheel 12. A stirring blade 16 is fixedly connected to the outer wall of the stirring rod 15. The stirring rod 15 rotates under the drive of the power, which drives the stirring blade 16 to rotate. The stirring blade 16 stirs the raw materials in the reaction vessel 2, so that the raw materials are fully mixed and the uniformity and efficiency of the reaction are improved.

[0028] Reference Figure 1 - Figure 3 The outer wall of the baffle 7 is slidably connected to the inner wall of the feed pipe 3. The baffle 7 is used to control the opening and closing of the feed pipe 3. The outer wall of the scraper 18 is slidably connected to the inner wall of the reaction vessel 2. The scraper 18 is used to scrape the material from the inner wall of the reaction vessel 2. The threaded rod 19 is externally rotatably connected to the inside of the reaction vessel 2. The threaded rod 19 is used to drive the scraper 18 to move. The outer wall of the stirring rod 15 is rotatably connected to the inner wall of the reaction vessel 2. The stirring rod 15 is used to drive the stirring blade 16 to rotate. The outer wall of the tilting disc 9 is rotatably connected to the inner wall of the feed pipe 3. The tilting disc 9 is used to prevent the feed pipe 3 from being blocked.

[0029] Specifically, the outer wall of the baffle 7 is slidably connected to the inner wall of the feed pipe 3. The baffle 7 is used to control the opening and closing of the feed pipe 3. By precisely controlling the position of the baffle 7 inside the feed pipe 3, the flow rate of the raw material entering the reaction vessel 2 can be controlled to adjust the feeding speed. The outer wall of the scraper 18 is slidably connected to the inner wall of the reaction vessel 2. The scraper 18 is used to scrape the material from the inner wall of the reaction vessel 2. By moving the scraper 18 up and down, residual material adhering to the inner wall of the reaction vessel 2 can be removed, ensuring the cleanliness of the inside of the reaction vessel 2. The threaded rod 19 is used to drive the scraper 18 to move. By rotating the threaded rod 19, the material can be removed. The scraper 18 is adjusted up and down to complete the comprehensive scraping and cleaning of the inner wall of the reaction vessel 2. The outer wall of the stirring rod 15 is rotatably connected to the inner wall of the reaction vessel 2. The stirring rod 15 is used to drive the stirring blade 16 to rotate. During the reaction, the rotation of the stirring rod 15 causes the stirring blade 16 to continuously stir the raw materials, promote the mixing and reaction between the raw materials, and improve the reaction effect. The outer wall of the tilting plate 9 is rotatably connected to the inner wall of the feed pipe 3. The tilting plate 9 is used to prevent the feed pipe 3 from being blocked. Its rotation can prevent the raw materials from accumulating in the feed pipe 3 and ensure that the raw materials can smoothly enter the reaction vessel 2.

[0030] Working principle: When the reactor is needed, the support leg 1 firmly supports the reactor. During feeding, the motor 8 drives the rotating disc 9 to rotate, preventing blockage of the feed pipe 3. When the feeding speed needs to be adjusted, the output end of the cylinder 13 pushes the connecting rod 14, causing the baffle 7 to slide on the inner wall of the feed pipe 3, precisely controlling the opening and closing degree of the feed pipe 3. At the same time, the motor 8, in conjunction with the rotating disc 9, performs initial stirring of the raw materials, achieving uniform feeding and improving product purity and quality stability. During the reaction process, the connecting shaft 10 rotates, driving the worm gear 11. The worm wheel 12, which meshes with the worm gear 11, rotates, thereby driving the stirring. The rotating rod 15 and stirring blade 16 thoroughly stir the raw materials, improving the uniformity and efficiency of the reaction. When the reaction vessel 2 needs to be cleaned, the knob 21 is turned to drive the threaded rod 19 to rotate. Because the scraper 18 is threadedly connected to the threaded rod 19 and the slide rod 17 provides guidance, the scraper 18 moves up and down along the slide rod 17 to scrape off the residual material on the inner wall. At the same time, the nozzle 4 sprays cleaning liquid through the water pipe 20 to assist the scraper 18 in cleaning more thoroughly and avoid residual material affecting subsequent production. The entire reactor achieves efficient production of ursodeoxycholic acid and convenient maintenance of the equipment through the coordinated work of various components.

[0031] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A reaction vessel for the production of ursodeoxycholic acid, comprising a support leg (1), characterized in that: The upper surface of the support leg (1) is fixedly connected to the reaction vessel (2), the upper surface of the reaction vessel (2) is fixedly connected to the feed pipe (3), and the inner wall of the feed pipe (3) is provided with an adjustment component; The adjustment assembly includes a top cover (6), which is disposed on the upper surface of the feed pipe (3). A handle (5) is fixedly connected to the upper surface of the top cover (6). A motor (8) is fixedly connected to the outer wall of the feed pipe (3). A rotating disk (9) is rotatably connected to the output end of the motor (8). A connecting shaft (10) is fixedly connected to one end of the rotating disk (9). A baffle (7) is slidably connected to the inner wall of the feed pipe (3). A cylinder (13) is fixedly connected to the outer wall of the feed pipe (3). A connecting rod (14) is fixedly connected to the output end of the cylinder (13). The upper surface of the connecting rod (14) is fixedly connected to the lower surface of the baffle (7).

2. The reaction vessel for producing ursodeoxycholic acid according to claim 1, characterized in that: The inner wall of the reaction vessel (2) is fixedly connected to a slide rod (17), the outer wall of the slide rod (17) is slidably connected to a scraper (18), the inner wall of the scraper (18) is threadedly connected to a threaded rod (19), one end of the threaded rod (19) is fixedly connected to a knob (21), the inner wall of the reaction vessel (2) is fixedly connected to a nozzle (4), one end of the nozzle (4) is fixedly connected to a water pipe (20).

3. The reaction vessel for producing ursodeoxycholic acid according to claim 1, characterized in that: A worm (11) is fixedly connected to the outer wall of the connecting shaft (10), a worm wheel (12) is meshed with the outer wall of the worm (11), a stirring rod (15) is fixedly connected to the outer wall of the worm wheel (12), and a stirring blade (16) is fixedly connected to the outer wall of the stirring rod (15).

4. The reaction vessel for producing ursodeoxycholic acid according to claim 1, characterized in that: The outer wall of the baffle (7) is slidably connected to the inner wall of the feed pipe (3), and the baffle (7) is used to control the opening and closing of the feed pipe (3).

5. The reaction vessel for producing ursodeoxycholic acid according to claim 2, characterized in that: The outer wall of the scraper (18) is slidably connected to the inner wall of the reaction vessel (2), and the scraper (18) is used to scrape the material from the inner wall of the reaction vessel (2).

6. The reaction vessel for producing ursodeoxycholic acid according to claim 2, characterized in that: The threaded rod (19) is externally rotatably connected to the inside of the reaction vessel (2), and the threaded rod (19) is used to drive the scraper (18) to move.

7. The reaction vessel for producing ursodeoxycholic acid according to claim 3, characterized in that: The outer wall of the stirring rod (15) is rotatably connected to the inner wall of the reaction vessel (2), and the stirring rod (15) is used to drive the stirring blade (16) to rotate.

8. The reaction vessel for producing ursodeoxycholic acid according to claim 1, characterized in that: The outer wall of the rotating disc (9) is rotatably connected to the inner wall of the feed pipe (3), and the rotating disc (9) is used to prevent the feed pipe (3) from being blocked.

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