Customized porous titanium alloy jaw defect restoration

Abstract

The utility model discloses a customized porous titanium alloy jaw defect restoration which comprises a restoration body, the restoration body comprises a surface layer, a middle layer and a core layer, the middle layer is arranged on the outer side of the core layer, the surface layer is arranged on the outer side of the middle layer, a first through hole is formed in the surface layer, a second through hole is formed in the middle layer, and a third through hole is formed in the core layer. The restoration body is divided into the surface layer, the middle layer and the core layer, the through holes with different hole diameters are formed in the layers, the surface layer has the small hole diameter and the high porosity so that cell adhesion and initial bone ingrowth can be promoted, the hole diameter and the porosity of the middle layer are moderate, and the bone ingrowth rate can be increased. According to the present invention, the core layer has a large pore size and a low porosity, such that the overall mechanical strength and stability can be ensured, and the suitable mechanical support can be provided while the further osseointegration can be promoted, and the core layer has a large pore size and a low porosity. According to the layered design method, the characteristics of different layers are fully utilized, so that the optimal repairing effect is achieved.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to a customized porous titanium alloy jawbone defect repair body. Background Technology

[0002] Custom-designed porous titanium alloy jawbone defect prostheses are highly personalized medical implants that fully utilize modern digital technologies, such as CT scans and 3D printing, to be tailored to each patient's specific jawbone defect. The design goal of these prostheses is to significantly improve treatment outcomes, shorten surgical time, reduce postoperative complications, and greatly improve patient prognosis and quality of life.

[0003] However, despite significant advancements in many aspects of existing custom-designed porous titanium alloy jawbone prostheses, some shortcomings remain in practical application. In particular, the uniform pore size across the prosthesis makes it difficult to meet the diverse biological needs at different levels. For instance, the surface layer requires smaller pores to promote osteoblast adhesion and proliferation, while the interior requires larger pores to provide sufficient mechanical strength and support. The inability of a single-pore design to simultaneously satisfy these needs impacts biocompatibility.

[0004] There are currently no effective solutions to the problems in the relevant technologies. Utility Model Content

[0005] In response to the problems in related technologies, this utility model proposes a customized porous titanium alloy jawbone defect repair body to overcome the aforementioned technical problems existing in the existing related technologies.

[0006] Therefore, the specific technical solution adopted by this utility model is as follows:

[0007] A customized porous titanium alloy jawbone defect prosthesis includes a prosthesis body, which includes a surface layer, a middle layer and a core layer. The middle layer is located outside the core layer, the surface layer is located outside the middle layer, the surface layer has a first through hole, the middle layer has a second through hole, and the core layer has a third through hole.

[0008] Furthermore, to facilitate the installation of the restoration body, fixing plates are provided on both sides of the restoration body, and mounting holes are provided on the fixing plates.

[0009] Furthermore, in order to promote the integration of the prosthesis body and fixation plate with the host bone, and to provide local high concentrations of drug therapy, prevent infection, promote bone healing, and reduce systemic side effects, a drug-release coating is applied to the outer surface layer, and a bioactive coating is applied to the outer surface of the prosthesis body and fixation plate.

[0010] Furthermore, to facilitate cell adhesion and proliferation, the pore size of the first through-hole is 100-300 μm.

[0011] Furthermore, to facilitate the growth and permeation of new bone tissue, the pore size of the second through-hole is 300-600 μm.

[0012] Furthermore, to facilitate the transport of macromolecules and the penetration of newly formed bone tissue, the pore size of the third through-pore is 600-1000 μm.

[0013] Furthermore, the bioactive coating is composed of hydroxyapatite.

[0014] The beneficial effects of this utility model are as follows:

[0015] (1) By dividing the prosthesis body into three different layers—a surface layer, a middle layer, and a core layer—and setting through-pores of different diameters in each layer, the surface layer has smaller pores and higher porosity, which helps promote cell adhesion and initial bone ingrowth. The middle layer has moderate pore size and porosity, providing appropriate mechanical support and promoting further osseointegration. The core layer has larger pores and lower porosity to ensure overall mechanical strength and stability. This layered design method makes full use of the characteristics of different layers to achieve the best repair effect.

[0016] (2) By applying a bioactive coating to the outside of the prosthesis body and fixation plate, the integration of the prosthesis body and fixation plate with the host bone can be promoted, the stability and functionality of the prosthesis can be improved, and by setting a drug release coating, infection can be prevented, bone healing can be promoted, and systemic side effects can be reduced. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a front view of a customized porous titanium alloy jawbone defect repair body according to an embodiment of the present utility model;

[0019] Figure 2 This is a side view of a customized porous titanium alloy jawbone defect repair body according to an embodiment of the present utility model;

[0020] Figure 3 This is a structural diagram of a customized porous titanium alloy jawbone defect repair body according to an embodiment of the present utility model.

[0021] In the picture:

[0022] 1. Body of the prosthesis; 2. Surface layer; 3. Intermediate layer; 4. Core layer; 5. First through hole; 6. Second through hole; 7. Third through hole; 8. Fixation plate; 9. Mounting hole; 10. Drug release coating; 11. Bioactive coating. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] According to an embodiment of the present invention, a customized porous titanium alloy jawbone defect repair body is provided.

[0025] Example 1

[0026] like Figures 1-3As shown, the customized porous titanium alloy jawbone defect repair body according to an embodiment of this utility model includes a repair body 1. The repair body 1 includes a surface layer 2, an intermediate layer 3, and a core layer 4. The intermediate layer 3 is located outside the core layer 4, and the surface layer 2 is located outside the intermediate layer 3. The surface layer 2 has a first through-hole 5 with a pore diameter of 100-300 μm and a high porosity, which can promote the rapid growth and vascularization of bone cells. The intermediate layer 3 has a second through-hole 6 with a pore diameter of 300-600 μm, which is conducive to the growth and infiltration of new bone tissue. The core layer 4 has a third through-hole 7 with a pore diameter of 600-1000 μm. The μm diameter facilitates the transport of macromolecules and the penetration of newly formed bone tissue. The prosthesis body 1 has fixation plates 8 on both sides, with mounting holes 9 on the fixation plates 8. A drug-release coating 10 is applied to the outer side of the surface layer 2. The drug-release coating 10 can be made of antibiotics, growth factors, etc. A bioactive coating 11 is applied to the outer sides of the prosthesis body 1 and fixation plates 8. The bioactive coating 11 is composed of hydroxyapatite, a non-toxic and non-irritating material that does not cause rejection by the immune system, making it suitable for long-term implantation. Furthermore, the surface of hydroxyapatite has good cell affinity, promoting bone cell adhesion, proliferation, and differentiation, thus accelerating bone tissue regeneration and repair. Through this design, the prosthesis body 1 is divided into three distinct layers: a surface layer 2, a middle layer 3, and a core layer 4. Different pore sizes are incorporated into each layer, significantly improving the prosthesis's biocompatibility, bone integration capacity, and mechanical properties. This layered design fully utilizes the characteristics of different layers to achieve optimal repair results. First, the surface layer 2 typically has a smaller pore size and higher porosity, which helps promote cell adhesion and initial bone ingrowth. Small pore size provides more surface area, making it easier for cells to adhere and proliferate, thereby accelerating bone tissue repair and regeneration. Secondly, the intermediate layer 3 has moderate pore size and porosity, providing appropriate mechanical support while promoting further osseointegration. The design of the intermediate layer 3 needs to balance mechanical properties and biocompatibility to ensure that the prosthesis can effectively support bone tissue growth while bearing a certain mechanical load. Finally, the core layer 4 typically has a larger pore size and lower porosity to ensure overall mechanical strength and stability. The large pore size allows for the ingrowth of blood vessels and new bone, thereby improving the biocompatibility and osseointegration capacity of the prosthesis. In addition, the design of the core layer 4 also needs to consider the overall weight and elasticity of the prosthesis to accommodate the physiological movement of the mandible. During the installation of this prosthesis, the prosthesis body 1 is fixed by connecting it to the host bone through the mounting hole 9 with screws, and infection can be prevented by applying a drug-release coating 10 to the outer surface layer 2 of the prosthesis body 1.

[0027] In summary, by utilizing the above-mentioned technical solution of this utility model, the prosthesis body 1 is divided into three different layers: a surface layer 2, a middle layer 3, and a core layer 4. Different pore sizes are provided in each layer. The surface layer 2 has a smaller pore size and higher porosity, which helps promote cell adhesion and initial bone ingrowth. The middle layer 3 has a moderate pore size and porosity, providing appropriate mechanical support and promoting further bone integration. The core layer 4 has a larger pore size and lower porosity to ensure overall mechanical strength and stability. This layered design fully utilizes the characteristics of different layers to achieve the best repair effect. Furthermore, by applying a bioactive coating 11 to the outside of the prosthesis body 1 and the fixation plate 8, the integration of the prosthesis body 1 and the fixation plate 8 with the host bone can be promoted, improving the stability and functionality of the prosthesis. Finally, by providing a drug-release coating 10, infection can be prevented, bone healing promoted, and systemic side effects reduced.

[0028] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A customized porous titanium alloy jawbone defect repair body, characterized in that, The prosthesis includes a prosthesis body (1), which includes a surface layer (2), an intermediate layer (3) and a core layer (4). The intermediate layer (3) is located outside the core layer (4), the surface layer (2) is located outside the intermediate layer (3), the surface layer (2) has a first through hole (5), the intermediate layer (3) has a second through hole (6), and the core layer (4) has a third through hole (7). The diameter of the first through hole (5) is 100-300μm; the diameter of the second through hole (6) is 300-600μm; and the diameter of the third through hole (7) is 600-1000μm.

2. The customized porous titanium alloy jawbone defect repair body according to claim 1, characterized in that, The repair body (1) has fixing plates (8) on both sides, and the fixing plates (8) have mounting holes (9).

3. The customized porous titanium alloy jawbone defect repair body according to claim 1, characterized in that, The outer side of the surface layer (2) is coated with a drug-releasing coating (10), and the outer side of the prosthesis body (1) and the fixation plate (8) is coated with a bioactive coating (11).

4. A customized porous titanium alloy jawbone defect repair body according to claim 3, characterized in that, The bioactive coating (11) is composed of hydroxyapatite.

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