An implant device suitable for use in a mouse's first molar

By designing an implant device that includes a handle, a push rod, and an implant pin, and by using the method of breaking the connecting rod to quickly implant the implant pin, the problem of complex operation and large trauma of traditional mouse implantation is solved, and the operation is simplified and the experimental efficiency is improved.

CN224307448UActive Publication Date: 2026-06-02SHANGHAI TONGJI STOMATOLOGY HOSPITAL (TONGJI UNIVERSITY AFFILIATED STOMATOLOGY HOSPITAL)

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI TONGJI STOMATOLOGY HOSPITAL (TONGJI UNIVERSITY AFFILIATED STOMATOLOGY HOSPITAL)
Filing Date
2025-01-22
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Traditional mouse implant designs lack specificity, resulting in complex and time-consuming procedures that are prone to causing hemorrhagic shock, failing to meet the requirements for implantation stability and operational efficiency.

Method used

Design an implant device comprising a handle, a push rod, and an implant staple. The push rod and the implant staple are connected by a connecting rod that is easy to break. The connecting rod is broken by using appropriate torque to quickly implant the implant staple, simplifying the operation and reducing trauma.

Benefits of technology

It improves the safety and success rate of mouse experiments, reduces surgery time and mouse recovery time, and provides a more efficient experimental tool.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a kind of implant device suitable for mouse mandibular first molar, it is related to biomedical engineering field, provide a kind of implant device suitable for mouse mandibular first molar, including handle and the implant of being connected with handle, the implant includes the push rod being connected with handle and the implant nail being connected with push rod, connecting rod is equipped between push rod and implant nail, facilitating breaking down. The utility model is easy to operate, without jaw bone preparation hole, after removing 4 weeks old mouse mandibular first molar, manually implanting implant in distal root alveolar crypt, it can break under suitable torque, reduce operation time and mouse postoperative recovery time, improve experimental efficiency and success rate.
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Description

Technical Field

[0001] This invention relates to the field of biomedical engineering, and in particular to an implant device suitable for the first mandibular molar of mice. Background Technology

[0002] Traditional mouse implant designs often lack specificity, resulting in complex and time-consuming procedures. Furthermore, they are prone to adverse reactions such as hemorrhagic shock in mice during implantation, which seriously affects the success rate of experiments and the reliability of data.

[0003] Currently available implants typically fail to meet the experimental requirements for implant placement stability and operational efficiency. Furthermore, most mouse implant designs suffer from the following drawbacks and limitations: 1. The implant and screwdriver are separate components. Due to space constraints and limited manufacturing processes, they are often designed with a flathead screwdriver tip, which hinders stable grip during operation; 2. Considering the osseointegration of the implant, the implant is made of pure titanium, which is non-magnetic and cannot be designed as a magnetic screwdriver, further reducing the screwdriver's grip on the implant; 3. The diameter, length, and thread design of the implant are not conducive to immediate implant placement in fresh extraction sockets; 4. The mandibular molars in mice exhibit significant lingual inclination, and the mandible is difficult to stabilize during surgery, making implant placement challenging. Utility Model Content

[0004] To address the aforementioned problems, this invention aims to provide an implant device specifically designed for the mandibular first molars of 4-week-old mice. This device ensures ease of operation while significantly reducing trauma and bleeding risks to the mice, thereby improving the safety and success rate of experiments.

[0005] The main idea of ​​the technical solution adopted in this utility model is as follows: by setting a push rod and an implant screw in the implant device, and setting a thin connecting rod between the two, the connecting rod can be broken under appropriate torque after the implant screw is implanted into the mouse's alveolar socket, so that the implant screw can be quickly implanted into the mouse's alveolar socket, reducing the operation time and the mouse's postoperative recovery time, and improving the efficiency and success rate of the experiment.

[0006] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0007] An implant device for the mandibular first molar of mice is characterized in that it includes a handle and an implant connected to the handle, the implant including a push rod connected to the handle and an implant post connected to the push rod, and a connecting rod for easy breakage is provided between the push rod and the implant post.

[0008] Furthermore, the connecting rod consists of two inverted cones connected together after the tips have been ground flat.

[0009] Furthermore, both the push rod and the implant nail are integrally formed with a right-hand single-threaded thread.

[0010] Furthermore, the length of the connecting rod is 0.20 cm.

[0011] Furthermore, the push rod, planting nail, and connecting rod are all made of pure titanium.

[0012] The beneficial effects of this invention are as follows: Compared with the prior art, the improvement of this invention lies in its ease of operation. It requires no jawbone preparation; after extracting the first mandibular molar of a 4-week-old mouse, the implant is manually inserted into the distal root alveolar socket and breaks under appropriate torque. This reduces surgical time and postoperative recovery time for the mouse, improving experimental efficiency and success rate. This innovative design not only fills a market gap but also provides researchers with a more efficient and reliable experimental tool. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the overall structure of the implant device of this utility model.

[0014] Figure 2 This is a schematic diagram showing the overall structure of the implant device of this utility model.

[0015] Figure 3 This is an enlarged view of part A of this utility model.

[0016] Figure 4 This is a schematic diagram of the structure of the planting nail after the connecting rod of this utility model has been broken.

[0017] Figure 5 This is a schematic diagram of a section of hard tissue in the mandible of a mouse, showing the implant of the present invention.

[0018] Figure 6 This is a schematic diagram of the implant screw removed from the mandible according to this utility model.

[0019] The components include: 1. Handle, 2. Push rod, 3. Planting nail, and 4. Connecting rod. Detailed Implementation

[0020] To enable those skilled in the art to better understand the technical solution of this utility model, the technical solution of this utility model will be further described below in conjunction with the accompanying drawings and embodiments.

[0021] Please see Figures 1-6To simplify the procedure of implanting dental implants into the mandible of mice and reduce trauma to the mice, this application discloses an implant device suitable for the mandibular first molar of mice, including a handle 1 and an implant connected to the handle 1. The implant includes a push rod 2 connected to the handle 1 and an implant pin 3 connected to the push rod 2. A connecting rod 4 for easy breakage is provided between the push rod 2 and the implant pin 3. Figure 1 As shown, the connecting rod 4 is a cylindrical shape with a concave center. The concave part is relatively thin, making it easy to break the connecting rod 4 in the middle.

[0022] Specifically, such as Figure 2 and Figure 3 As shown, in order to facilitate the breaking of the connecting rod 4, the connecting rod 4 of this application is preferably two inverted cones connected after the tips are ground flat, and the connection point of the two inverted cones is the narrowest point, with a diameter of 0.20 mm. When the implant 3 is implanted into the first mandibular molar of the mouse, the connecting rod 4 can be broken. Due to the unique design of the connecting rod 4, the connecting rod 4 can be easily broken from the narrowest point, and the height of the broken connecting rod 4 is lower than that of the adjacent tooth, so it will not cause harm to the mouse.

[0023] The handle 1 of this application is made of plastic, 2.5mm wide and 20mm long, with a regular hexagonal cross-section, which is convenient for gripping and applying force.

[0024] The implant nail 3 is 1.8 mm long, and the connecting rod 4 is 0.20 cm long. It is designed to break under appropriate torque, specifically 5-8 N·cm.

[0025] Both the push rod 2 and the implant nail 3 are provided with right-hand single-threaded threads. The diameter of the push rod (including the thread) is D=0.65mm, the diameter of the implant nail 3 is d=0.45mm, the thread depth is 0.18mm, and the thread pitch is 0.27mm.

[0026] The push rod 2 can also be without threads.

[0027] It should be noted that the push rod 2, planting nail 3, and connecting rod 4 are all made of pure titanium and are machined using a CNC multi-functional machine tool to ensure biocompatibility and mechanical stability.

[0028] Example

[0029] When using the implant described in this application, 4-week-old C57 mice were anesthetized, placed in a supine position, and the mouth and tongue were pulled back to expose the mandibular first molar. Using a #5 injection needle, force was applied to the buccal surface to loosen the molar, which was then removed using micro-forceps. Local pressure was applied to stop bleeding. The implant post 3 was then slowly and manually screwed into the distal root of the extraction socket. When the neck was level with the gingiva, the connecting rod 4 broke due to the appropriate torque. After the mouse regained consciousness, it was returned to its enclosure.

[0030] Tissue samples were taken from the mandible, heart, liver, spleen, lungs, and kidneys at 3, 7, 14, and 28 days post-surgery for sectioning. No biohazards were found.

[0031] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. An implant device suitable for the mandibular first molar in mice, characterized in that: It includes a handle (1) and an implant connected to the handle (1). The implant includes a push rod (2) connected to the handle (1) and an implant pin (3) connected to the push rod (2). A connecting rod (4) is provided between the push rod (2) and the implant pin (3) for easy breakage.

2. The implant device for the mandibular first molar of mice according to claim 1, characterized in that: The connecting rod (4) consists of two inverted cones connected together after the tips are ground flat.

3. The implant device for the mandibular first molar of mice according to claim 1, characterized in that: Both the push rod (2) and the planting nail (3) are integrally formed with a right-hand single thread.

4. The implant device for the mandibular first molar of a mouse according to claim 2, characterized in that: The length of the connecting rod (4) is 0.20cm.

5. The implant device for the mandibular first molar of mice according to claim 1, characterized in that: The push rod (2), planting nail (3), and connecting rod (4) are all made of pure titanium.