Anti-blocking sampling device of glycosylated hemoglobin instrument

Abstract

The utility model discloses an anti-clogging sampling device of a glycosylated hemoglobin instrument, and relates to the technical field of glycosylated hemoglobin analysis, the anti-clogging sampling device comprises a protein instrument shell, the top of the inner side wall of the protein instrument shell is fixedly provided with a support frame through a bolt, and the edge of one side of the support frame is movably connected with a moving assembly through a rotating shaft; a fixed table is fixedly mounted on the surface of one side of the moving assembly, an extension surface is arranged in the middle of the surface of one side of the fixed table, a sample injection pipe is connected to the extension surface of one side of the fixed table in a penetrating manner, and a hollow pipe body is movably connected to the inner arc surface of the sample injection pipe in a sleeving manner; according to the utility model, the fixed block slides along with the synchronous belt, so that the stability of transverse movement is ensured, and then the electric push rod is driven to enable the extension end of one side of the electric push rod to drive the fixed table to move downwards, so that the sample injection tube can stably move in the longitudinal direction, and the sample injection tube is aligned to a test tube body through the transverse and longitudinal stable movement; liquid sample injection can be accurately carried out, and the possibility of blockage is reduced.

Description

Technical Field

[0001] This utility model relates to the field of glycated hemoglobin analysis technology, specifically to an anti-clogging sample injection device for a glycated hemoglobin analyzer. Background Technology

[0002] Glycated hemoglobin is a stable compound in the blood where glucose is covalently bonded to the terminal valine residues of the hemoglobin chain. Its content is positively correlated with blood glucose concentration and reflects the average blood glucose level over the past 2-3 months. It has extremely important value in the diagnosis, treatment monitoring, and disease assessment of diabetes.

[0003] In the long-term management of diabetes, HbA1c levels can help doctors determine whether a patient's blood sugar is well controlled. If HbA1c is higher than the target value, it means that the patient's blood sugar has not been well controlled in the past period of time, and the treatment plan needs to be adjusted, such as changing the dosage or type of medication, adjusting diet and exercise plans, etc.

[0004] A key issue facing existing glycated hemoglobin analyzers is that blood samples are complex biological samples containing components such as blood cells, proteins, and clotting factors. Blood cells may clump together, or substances such as fibrin in the sample may deposit in the sample inlet channel. For example, when a blood sample is left for a period of time after collection, the clotting process begins, and fibrinogen is converted into fibrin. This fibrin can easily clog the tiny channels of the sample inlet device, preventing the sample from entering the detection system properly or resulting in an inaccurate sample volume. It also reduces detection efficiency, requires time to clean blockages or replace parts, increases the patient's waiting time for test results, and increases the maintenance cost of the instrument.

[0005] In view of the above, this application is hereby submitted. Utility Model Content

[0006] The purpose of this invention is to provide an anti-clogging sample injection device for a glycated hemoglobin analyzer, so as to solve the problems mentioned in the background art.

[0007] To solve the above-mentioned technical problems, this utility model provides an anti-clogging sample injection device for a glycated hemoglobin analyzer, including an analyzer housing. A support frame is fixedly installed on the top of the inner side wall of the analyzer housing by bolts. A movable component is movably connected to one side edge of the support frame via a rotating shaft. A fixed platform is fixedly installed on one side surface of the movable component. An extension surface is provided in the middle of one side surface of the fixed platform. A sample injection tube is connected through the extension surface of one side of the fixed platform. A hollow tube body is movably sleeved on the inner arc surface of the sample injection tube.

[0008] Furthermore, a support pipe section is provided on one side of the inner arc surface of the hollow tube body. The inner arc surface of the hollow tube body is provided with internal threads. A bearing is movably sleeved on the inner arc surface of the support pipe section. A helical spring head is fixedly installed on the inner arc surface of the bearing.

[0009] Furthermore, the outer arc surface of the helical spring head is movably adapted to the inner arc surface of the injection tube, and the bearings are all connected to the internal threads of the helical spring head and the hollow tube body, with the sample outlet head threadedly connected to the outer arc surface of the internal thread.

[0010] Furthermore, the outer arc surface of the sample outlet head is provided with an external thread, the external thread on the sample outlet head is connected with the internal thread, and a sealing end is provided at one edge of the outer arc surface of the sample outlet head, the outer arc surface of the sealing end is in contact with the inner arc surface of the hollow tube.

[0011] Furthermore, the front end of the sample outlet head is provided with anti-slip ridges, and the front end of the anti-slip ridges is connected to the injection tube.

[0012] Furthermore, a test tube rack is fixedly installed on the upper surface of the protein analyzer housing. The test tube rack has a through hole, and a test tube body is connected through the through hole. The hollow tube body is placed on top of the test tube body. The moving component includes a synchronous wheel fixedly installed on one side of the support frame. A synchronous belt is movably sleeved on the outer arc surface of the synchronous wheel.

[0013] Furthermore, a transverse guide rail is fixedly installed on one side of the support frame by bolts, a fixing block is fixedly installed on one side of the timing belt, a longitudinal guide rail is fixedly installed on one side of the fixing block, and an electric push rod is fixedly installed on the upper end of the fixing block.

[0014] Furthermore, one end of the electric push rod is bolted to a fixed platform, and four sliders are fixedly installed on the back of the fixed platform. One side of each of the four sliders is movably engaged with a longitudinal guide rail.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] 1. By sliding the fixed block along the synchronous belt, the stability of lateral movement is ensured. Then, by driving the electric push rod, one of its extended ends moves the fixed stage downward, ensuring that the injection tube can move smoothly in the longitudinal direction. The injection tube is aligned with the test tube body through smooth lateral and longitudinal movement, which can accurately inject liquid and reduce the possibility of blockage.

[0017] 2. The spiral structure of the spiral spring head makes it difficult for impurities to deposit on its surface when the sample passes through. Since the sample flows dynamically inside the spiral spring head, impurities will be washed away by the subsequent sample flow when they come into contact with the surface of the spiral spring head. The adhesion of impurities to the pipe wall will be greatly reduced, thus reducing blockage caused by long-term accumulation of impurities. Attached Figure Description

[0018] Figure 1 A schematic diagram of the connection structure between the moving component and the hollow tube of an anti-clogging sample injection device for a glycated hemoglobin analyzer;

[0019] Figure 2 This is a partial structural schematic diagram of an anti-clogging sample inlet device for a glycated hemoglobin analyzer;

[0020] Figure 3 A schematic diagram of the cross-sectional structure of the injection tube of an anti-clogging sample injection device for a glycated hemoglobin analyzer;

[0021] Figure 4 A schematic diagram of the disassembled structure of the hollow tube body of an anti-clogging sample injection device for a glycated hemoglobin analyzer;

[0022] Figure 5 A schematic cross-sectional view of the sample outlet head of an anti-clogging sample inlet device for a glycated hemoglobin analyzer;

[0023] Figure 6 This is a schematic diagram of the overall structure of an anti-clogging sample injection device for a glycated hemoglobin analyzer.

[0024] In the diagram: 1. Protein analyzer housing; 2. Support frame; 3. Moving component; 301. Synchronous pulley; 302. Synchronous belt; 303. Horizontal guide rail; 304. Fixing block; 305. Longitudinal guide rail; 306. Electric push rod; 307. Slider; 4. Fixed platform; 5. Sample dispensing tube; 6. Hollow tube body; 601. Support tube section; 602. Internal thread; 603. Bearing; 604. Helical spring head; 7. Sample dispensing head; 701. Sealing end; 702. Anti-slip texture; 703. Coagulation tube; 8. Test tube rack; 9. Test tube body. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figure 1 , Figure 2 and Figure 6This utility model provides a technical solution: a clogging-resistant sample feeding device for a glycated hemoglobin analyzer, comprising a synchronous wheel 301 fixedly installed on one side of a support frame 2, a synchronous belt 302 movably sleeved on the outer arc surface of the synchronous wheel 301, a transverse guide rail 303 fixedly installed on one side of the support frame 2 by bolts, a fixing block 304 fixedly installed on one side of the synchronous belt 302, a longitudinal guide rail 305 fixedly installed on one side of the fixing block 304, an electric push rod 306 fixedly installed on the upper end of the fixing block 304, one end of the electric push rod 306 being bolted to a fixed platform 4, and four sliders 307 fixedly installed on the back of the fixed platform 4, with one side of each slider 307 movably engaged with the longitudinal guide rail 305.

[0027] For details, please refer to [link / reference]. Figure 1 and Figure 2 The sampled injection tube 5 is placed on the test tube rack 8, and then placed in the fixed platform 4. The synchronous wheel 301 is driven to rotate by the motor. The fixed block 304 is fixedly connected to the synchronous belt 302. The fixed block 304 slides with the synchronous belt 302 to ensure the stability of the lateral movement. Then, the electric push rod 306 is driven to move the fixed platform 4 downward by its extended end, which ensures that the injection tube 5 can move smoothly in the longitudinal direction. The injection tube 5 is aligned with the test tube body 9 through the smooth lateral and longitudinal movement, which can accurately inject liquid and reduce the possibility of blockage.

[0028] Meanwhile, the X-axis and Y-axis moving components 3 enable the injection tube 5 to move precisely in multiple directions, ensuring that the needle can move straight in and out without causing movement in other directions inside the test tube body 9.

[0029] Furthermore, during the sample introduction process of the protein analyzer, the precise positioning of the moving component 3 ensures that the sample is accurately placed in the test tube body 9. For example, for trace amounts of protein samples, such as the detection of monoclonal antibody proteins in biopharmaceutical research and development, precise positioning allows the sample to enter the test tube body 9 at the correct angle and position, avoiding sample residue or splashing at the edge of the test tube body 9. Since the amount of these precious protein samples may be very small, even a small loss may affect the subsequent test results.

[0030] Please continue reading. Figure 3 , Figure 4 and Figure 5A support frame 2 is fixedly installed on the top of the inner wall of the protein analyzer housing 1 by bolts. A moving component 3 is movably connected to one side edge of the support frame 2 via a rotating shaft. A fixed platform 4 is fixedly installed on one side surface of the moving component 3. An extension surface is provided in the middle of one side surface of the fixed platform 4. A sample injection tube 5 is connected through the extension surface of one side of the fixed platform 4. A hollow tube body 6 is movably sleeved on the inner arc surface of the sample injection tube 5. A support tube section 601 is provided on one side of the inner arc surface of the hollow tube body 6. An internal thread 602 is provided on the inner arc surface of the hollow tube body 6. A bearing 603 is movably sleeved on the inner arc surface of the support tube section 601. A helical spring head 604 is fixedly installed on the inner arc surface of the bearing 603. The outer arc surface of the helical spring head 604 is movably adapted to the inner arc surface of the sample injection tube 5. The bearing 603 is connected to the helical spring head 604 and the internal thread 602 in the hollow tube body 6. A sample outlet head 7 is threadedly connected to the outer arc surface of the internal thread 602.

[0031] pass Figure 3 The hollow tube 6 is inserted into the injection tube 5. By rotating the support tube section 601, the support tube section 601 will move on the internal thread 602. When the bearing 603 on the support tube section 601 rotates, it drives the spiral spring head 604 to rotate. One end of the hollow tube 6 of the spiral spring head 604 is used to clear the blockage in the injection tube 5. Since the spiral spring head 604 is a conical spiral spring, it has a squeezing force and drilling force on the blockage in the pipe when it rotates, which makes it easy to loosen the blockage in the severely blocked pipe, and thus facilitates the discharge of the blockage from the pipe to clear the pipe.

[0032] Specifically, the direction in which the helical spring head 604 extends into the hollow tube body 6 is the direction in which the helical spring head 604 squeezes and drills into the blockage when clearing the pipe. As the pitch of the helical spring head 604 decreases, the spring coils of the helical spring head 604 become denser, making the head of the helical spring head 604 harder and more powerful when rotating and drilling, thus making it easier to loosen the blockage.

[0033] The material used for the support tube section 601 can be metal, such as stainless steel, copper, iron, etc. Since the hardness of the material used for the support tube section 601 is greater than that of the material of the hollow tube body 6, the support tube section 601 can more reliably support the helical spring head 604.

[0034] The spiral structure of the spiral spring head 604 makes it difficult for impurities to deposit on its surface when the sample passes through. Since the sample flows dynamically inside the spiral spring head 604, impurities will be washed away by the subsequent sample flow when they come into contact with the surface of the spiral spring head 604. The adhesion of impurities to the pipe wall will be greatly reduced, thus reducing blockage caused by long-term accumulation of impurities.

[0035] The outer arc surface of the sample outlet head 7 is provided with an external thread, which is connected to the internal thread 602. A sealing end 701 is provided at one edge of the outer arc surface of the sample outlet head 7. The outer arc surface of the sealing end 701 fits against the inner arc surface of the hollow tube body 6. The front end of the sample outlet head 7 is provided with an anti-slip ridge 702, and the front end of the anti-slip ridge 702 is connected to the condensate injection tube 703.

[0036] Furthermore, through Figure 5 When the sealing end 701 is inserted into the hollow tube 6, it achieves a sealing effect. The surface of the sample outlet 7 is conical, and the diameter of the cone gradually increases along the opening direction of the hollow tube 6, with the maximum diameter being greater than the outer diameter of the hollow tube 6. When the sample outlet 7 is sleeved with the hollow tube 6, the injection tube 703 is inserted into the sample outlet 7, and at the same time, the inner surface of the end of the hollow tube 6 abuts against the inner surface of the sealing end 701 to prevent external air or dust from entering the hollow tube 6, thus achieving a sealing effect.

[0037] When the injection tube 5 is in contact with dust for a long time, dust particles may wear down the surface of the needle, affecting the accuracy and service life of the injection needle. The sealing end 701 measure can reduce the contact between dust and mechanical parts, allowing the mechanical parts to work in a relatively clean environment.

Claims

1. A clogging-resistant sample inlet device for a glycated hemoglobin analyzer, characterized in that: The apparatus includes a protein analyzer housing (1), a support frame (2) is fixedly installed on the top of the inner wall of the protein analyzer housing (1) by bolts, a moving component (3) is movably connected to one side edge of the support frame (2) by a rotating shaft, a fixed platform (4) is fixedly installed on one side surface of the moving component (3), an extension surface is provided in the middle of one side surface of the fixed platform (4), a sample injection tube (5) is connected through the extension surface of one side of the fixed platform (4), and a hollow tube body (6) is movably sleeved on the inner arc surface of the sample injection tube (5).

2. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 1, characterized in that: The hollow tube (6) has a support tube section (601) on one side of its inner arc surface. The hollow tube (6) has an internal thread (602) on its inner arc surface. The support tube section (601) has a bearing (603) movably sleeved on its inner arc surface. The bearing (603) has a helical spring head (604) fixedly installed on its inner arc surface.

3. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 2, characterized in that: The outer arc surface of the helical spring head (604) is movably adapted to the inner arc surface of the injection tube (5). The bearings (603) are all connected to the internal threads (602) inside the helical spring head (604) and the hollow tube body (6). The outer arc surface of the internal thread (602) is threaded with the sample outlet head (7).

4. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 3, characterized in that: The outer arc surface of the sample outlet (7) is provided with an external thread, and the external thread on the sample outlet (7) is connected to the internal thread (602). A sealing end (701) is provided at one edge of the outer arc surface of the sample outlet (7), and the outer arc surface of the sealing end (701) is in contact with the inner arc surface of the hollow tube (6).

5. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 4, characterized in that: The front end of the sample outlet head (7) is provided with anti-slip ridges (702), and the front end of the anti-slip ridges (702) is connected to the injection tube (703).

6. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 2, characterized in that: The upper surface of the protein analyzer housing (1) is fixedly mounted with a test tube rack (8). The test tube rack (8) has a through hole. A test tube body (9) is connected through the through hole on the test tube rack (8). The hollow tube body (6) is placed on top of the test tube body (9). The moving component (3) includes a synchronous wheel (301) fixedly mounted on one side of the support frame (2). A synchronous belt (302) is movably sleeved on the outer arc surface of the synchronous wheel (301).

7. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 6, characterized in that: A transverse guide rail (303) is fixedly installed on one side of the support frame (2) by bolts, a fixing block (304) is fixedly installed on one side of the synchronous belt (302), a longitudinal guide rail (305) is fixedly installed on one side of the fixing block (304), and an electric push rod (306) is fixedly installed on the upper end of the fixing block (304).

8. The anti-clogging sample introduction device for a glycated hemoglobin analyzer as described in claim 7, characterized in that: One end of the electric push rod (306) is bolted to the fixed platform (4). A slider (307) is fixedly installed on the back of the fixed platform (4). There are four sliders (307), and one side of each slider (307) is movably engaged with the longitudinal guide rail (305).

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