Autoimmune disease gene detection device

By introducing protective strips, protective frames, slide rails, and electric telescopic rods into the gene detection device, the problem of cross-contamination between the detection chip and the reagent kit is solved, thereby improving the detection accuracy and the reliability of the results.

CN223906825UActive Publication Date: 2026-02-13BEIJING OUMENG WEIYI MEDICAL LAB CO LTD
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Patent Information

Application Number
CN202422904787.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-27
Publication Date
2026-02-13
Estimated Expiration
2034-11-27

AI Technical Summary

Technical Problem

In existing gene detection devices, the isolation and protection measures between the detection chip and the reagent to be tested are insufficient, leading to cross-contamination and affecting the accuracy and validity of the test results.

Method used

The design incorporates protective strips, a protective frame, slide rails, an electric telescopic rod, and a protective shell to achieve independent isolation and protection between the detection chip and the reagent kit. The coordinated movement of the electric telescopic rod and slide rails ensures that the reagent kit is isolated from the outside world and enables precise insertion and repositioning of the detection probe during testing.

Benefits of technology

This effectively reduces cross-contamination between the detection chip and the reagent kit, improving detection accuracy and the validity of results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of gene detection, in particular to an autoimmune disease gene detection device which comprises two supporting frames fixedly installed at the top of a base, first electric telescopic rods are fixedly installed on the inner sides of the supporting frames, and first movable plates are installed at the output ends of the first electric telescopic rods. A first movable plate is driven by a first electric telescopic rod, so that the first movable plate is in sealed butt joint with a protection frame, a kit above the first movable plate is protected, reagents in the kit are better isolated from the outside, a round hole is shielded and sealed by a baffle, the kit can be isolated from the outside when detection is not carried out, and the detection efficiency is improved. By arranging a second protective shell and a baffle, the detection chip can be isolated and protected, so that the detection chip and the kit are independently protected, cross contamination between the detection chip and the kit is reduced, the accuracy of the detection device is improved, and a final detection result is effective.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of gene detection, specifically to an autoimmune disease gene detection device. BACKGROUND

[0002] Autoimmune diseases are caused by the human immune system attacking normal cells, which in turn causes the death of normal cells or inflammation of tissues, which is called autoimmune diseases, and can be roughly divided into "direct attack by immune cells" and "attack by immune cells to produce antibodies or cause other immune reactions".

[0003] Gene detection is a technology for detecting DNA, which takes peripheral venous blood or other tissue cells of the detected person, amplifies the gene information, and detects the DNA molecular information in the cells of the detected person through a specific device to analyze the gene type and gene defect and whether the expression function is normal, and gene detection requires a gene detection device.

[0004] In the current detection process, a significant problem is that the isolation and protection measures between the detection chip and the test reagent are insufficient, which easily leads to cross contamination between the two, which in turn affects the accuracy of the detection device, makes it difficult to accurately determine the final detection result, and reduces the effectiveness of the entire detection process. UTILITY MODEL CONTENT

[0005] The utility model aims at providing an autoimmune disease gene detection device, which has isolation and protection and reduces cross infection.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: an autoimmune disease gene detection device, comprising two support frames fixedly installed on the top of the base, a first electric telescopic rod is fixedly installed on the inner side of the support frame, a first movable plate is installed on the output end of the first electric telescopic rod, a protective strip is fixedly installed on the top of the first movable plate, a fixed plate is fixedly sleeved on the outer side of the support frame, a protective frame is fixedly installed on the bottom of the fixed plate, a first protective shell is fixedly installed on the top of the fixed plate, a slide rail is fixedly installed on the inner side of the first protective shell, a baffle is slidably installed on the inner side of the slide rail, a second movable plate is arranged above the fixed plate, a second protective shell is fixedly installed on the top of the second movable plate, a detection chip is fixedly installed on the inner side of the second protective shell, and a detection needle is fixedly installed on the bottom of the detection chip.

[0007] In order to facilitate the movement, as an autoimmune disease gene detection device of the utility model preferably, the top of base is fixedly installed with support column, the baffle is slidably connected with the support column, the surface of fixed plate is provided with a round hole, the round hole is located at the inner side of slide rail, the side of support column is fixedly installed with return spring, one end of return spring is fixedly connected with the top of baffle.

[0008] In order to facilitate the pulling, as an autoimmune disease gene detection device of the utility model preferably, the bottom of second movable plate is fixedly installed with arc block, one end of the inner side of baffle is rotatably installed with roller, the arc block passes through the inner side of baffle, the arc block is rotatably installed with roller, the arc block is slidably installed with support column.

[0009] In order to facilitate the change of position, as an autoimmune disease gene detection device of the utility model preferably, the top of second movable plate is fixedly installed with second electric telescopic rod on both sides, the low end of second electric telescopic rod is fixedly connected with the upper surface of fixed plate.

[0010] In order to facilitate the placement, as an autoimmune disease gene detection device of the utility model preferably, the upper surface of first movable plate is fixedly installed with placing seat, the inner side of placing seat is placed with reagent box.

[0011] In order to isolate and protect, as an autoimmune disease gene detection device of the utility model preferably, the protective strip is correspondingly arranged above and below the protective frame, and the placing seat is located on the inner side of the protective strip and corresponds to the position of the protective frame.

[0012] In order to facilitate the shielding, as an autoimmune disease gene detection device of the utility model preferably, the baffle is slidably connected with the first protective shell, the baffle corresponds to the position of the round hole, and the first movable plate is located below the fixed plate.

[0013] Compared with the prior art, the utility model has the advantages that:

[0014] The first movable plate is driven by the first electric telescopic rod to be sealed and connected with the protective frame, so that the reagent box above the first movable plate is protected, the reagent in the reagent box is better isolated from the outside, the round hole is shielded and sealed by the baffle, the isolation of the reagent box from the outside can be ensured when detection is not performed, the detection chip can be isolated and protected by the second protective shell and the baffle, the detection chip and the reagent box are independently protected, cross contamination between the two is reduced, the accuracy of the detection device is improved, and the final detection result is effective. BRIEF DESCRIPTION OF DRAWINGS

[0015] Fig. 1The utility model discloses a top view three-dimensional structure drawing;

[0016] Fig. 2 The utility model discloses a left top view partial sectional three-dimensional structure drawing;

[0017] Fig. 3 The utility model discloses a right top view partial sectional three-dimensional structure drawing;

[0018] Fig. 4 The utility model discloses a partial three-dimensional structure drawing.

[0019] In the drawing: 1, base, 2, support frame, 3, first electric telescopic rod, 4, first movable plate, 5, fixed plate, 6, first protective shell, 7, second protective shell, 8, round hole, 9, second movable plate, 10, second electric telescopic rod, 11, detection needle, 12, detection chip, 13, protective strip, 14, placing seat, 15, reagent box, 16, protective frame, 17, support column, 18, sliding rail, 19, baffle, 20, roller, 21, arc block, 22, return spring. DETAILED DESCRIPTION

[0020] Please refer to Figs. 1 to 4 A kind of autoimmune disease gene detection device, including two support frames 2 of fixed installation at the top of base 1, the inner side of support frame 2 is fixedly installed with first electric telescopic rod 3, the output end of first electric telescopic rod 3 is installed with first movable plate 4, the top of first movable plate 4 is fixedly installed with protective strip 13, the outer side of support frame 2 is fixedly sleeved with fixed plate 5, the bottom of fixed plate 5 is fixedly installed with protective frame 16, the top of fixed plate 5 is fixedly installed with first protective shell 6, the inner side of first protective shell 6 is fixedly installed with sliding rail 18, the inner side of sliding rail 18 is slidably installed with baffle 19, the top of fixed plate 5 is provided with second movable plate 9, the top of second movable plate 9 is fixedly installed with second protective shell 7, the inner side of second protective shell 7 is fixedly installed with detection chip 12, the bottom of detection chip 12 is fixedly installed with detection needle 11.

[0021] In the embodiment: by setting protective strip 13, first movable plate 4 and protective frame 16 can be well contacted and sealed, better reagent box 15 above first movable plate 4 is isolated from the outside, by setting sliding rail 18, baffle 19 can better carry out horizontal sliding motion, when detection needle 11 detects reagent in reagent box 15, it can pass through first protective shell 6 and be inserted into reagent box 15 to carry out reagent detection operation.

[0022] As a technical optimization scheme of the utility model, the top of base 1 is fixedly installed with support column 17, baffle 19 is slidably sleeved with support column 17, the surface of fixed plate 5 is provided with round hole 8, round hole 8 is located at the inner side of slide rail 18, one side of support column 17 is fixedly installed with return spring 22, one end of return spring 22 is fixedly connected with the top of baffle 19.

[0023] In the embodiment: through setting support column 17, baffle 19 can be horizontally moved along support column 17, when not needing to detect reagent, baffle 19 can shield and protect round hole 8, through setting return spring 22, baffle 19 can be pulled and reset, the position of baffle 19 blocking round hole 8.

[0024] As a technical optimization scheme of the utility model, the bottom of second movable plate 9 is fixedly installed with arc block 21, one end inner side of baffle 19 is rotatably installed with roller 20, arc block 21 passes through the inner side of baffle 19, arc block 21 is rotatably installed with roller 20, arc block 21 is slidably installed with support column 17.

[0025] In the embodiment: through setting arc block 21, in the process of second movable plate 9 moving downward, arc block 21 will drive arc block 21 to slide and move downward along support column 17, so that arc block 21 and roller 20 roll and move, so that arc block 21 extrudes roller 20, so that roller 20 drives baffle 19 to slide and move along slide rail 18, so that round hole 8 leaks out to facilitate detection needle 11 to pass through round hole 8 and insert into reagent box 15 to detect reagent.

[0026] As a technical optimization scheme of the utility model, the top of second movable plate 9 is fixedly installed with second electric telescopic rod 10 on both sides, the low end of second electric telescopic rod 10 is fixedly connected with the upper surface of fixed plate 5.

[0027] In the embodiment: through setting second electric telescopic rod 10, second movable plate 9 can be driven to move upward or downward, so that second movable plate 9 drives detection needle 11 to insert into reagent box 15 to detect reagent.

[0028] As a technical optimization scheme of the utility model, the upper surface of first movable plate 4 is fixedly installed with placing seat 14, reagent box 15 is placed in the inner side of placing seat 14; protective strip 13 and protective frame 16 position correspond in up and down, placing seat 14 is located at the inner side of protective strip 13 and corresponds with the position of protective frame 16.

[0029] In the embodiment: through setting placing seat 14, reagent box 15 is placed stably, reagent box 15 can be placed directly below round hole 8, so that detection needle 11 can pass through round hole 8 to detect reagent in reagent box 15.

[0030] As a technical optimization scheme of the utility model, the baffle 19 is slidably sleeved with the first protective shell 6, the baffle 19 corresponds to the position of the round hole 8, and the first movable plate 4 is located below the fixed plate 5.

[0031] In the embodiment, the first protective shell 6 can protect the low end of the detection needle 11 and reduce the infection of the detection needle 11.

[0032] Working principle: first, the reagent to be detected is placed in the reagent box 15, the reagent box 15 is placed in the corresponding placing seat 14, then the first electric telescopic rod 3 is started to shrink to drive the first movable plate 4 to move upwards, so that the first movable plate 4 drives the reagent box 15 to move upwards, so that the protective frame 16 contacts and seals the protective strip 13 to isolate and protect the reagent box 15, when the detection operation is performed, the second electric telescopic rod 10 is started to shrink to drive the second movable plate 9 to move downwards, so that the detection needle 11 moves downwards, at this time, the second movable plate 9 drives the arc-shaped block 21 to extrude and roll the roller 20, so that the roller 20 drives the baffle 19 to move horizontally along the supporting column 17 and the sliding rail 18, so that the corresponding round hole 8 of the sliding rail 18 leaks out, at this time, the detection needle 11 penetrates through the round hole 8 and inserts into the reagent box 15 to detect the reagent, after the detection is completed, the second electric telescopic rod 10 is started to extend to drive the second movable plate 9 to reset, under the elastic action of the reset spring 22, the baffle 19 is reset, the second protective shell 7 is arranged to isolate and protect the detection chip 12, and cross infection is avoided.

[0033] The standard parts used in the utility model can be purchased from the market, the special-shaped parts can be ordered according to the description and the drawings, the specific connection mode of each part adopts the conventional means such as rivets and welding in the existing technology, the machinery, parts and equipment adopt the conventional type in the existing technology, the circuit connection adopts the conventional connection mode in the existing technology, which will not be described in detail here, the contents not described in detail in the specification belong to the existing technology known to the person skilled in the art, and all the electric equipment in the utility model is powered by an external power supply.

[0034] The above is only a preferred embodiment of the utility model, and does not limit the utility model, and any modification, equivalent replacement and improvement made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. An autoimmune disease gene detection device, comprising two support frames (2) fixedly installed on the top of a base (1), characterized in that: A first electric telescopic rod (3) is fixedly installed on the inner side of the support frame (2). A first movable plate (4) is installed at the output end of the first electric telescopic rod (3). A protective strip (13) is fixedly installed on the top of the first movable plate (4). A fixed plate (5) is fixedly sleeved on the outer side of the support frame (2). A protective frame (16) is fixedly installed at the bottom of the fixed plate (5). A first protective shell (6) is fixedly installed on the top of the fixed plate (5). A slide rail (18) is fixedly installed on the inner side of the first protective shell (6). A baffle (19) is slidably installed on the inner side of the slide rail (18). A second movable plate (9) is provided above the fixed plate (5). A second protective shell (7) is fixedly installed on the top of the second movable plate (9). A detection chip (12) is fixedly installed on the inner side of the second protective shell (7). A detection needle (11) is fixedly installed at the bottom of the detection chip (12).

2. The autoimmune disease gene detection device according to claim 1, characterized in that: A support column (17) is fixedly installed on the top of the base (1). The baffle (19) is slidably sleeved with the support column (17). A round hole (8) is opened on the surface of the fixing plate (5). The round hole (8) is located inside the slide rail (18). A return spring (22) is fixedly installed on one side of the support column (17). One end of the return spring (22) is fixedly connected to the top of the baffle (19).

3. The autoimmune disease gene detection device according to claim 2, characterized in that: An arc-shaped block (21) is fixedly installed at the bottom of the second movable plate (9). A roller (20) is rotatably installed on the inner side of one end of the baffle (19). The arc-shaped block (21) passes through the inner side of the baffle (19). The arc-shaped block (21) and the roller (20) are rolled together. The arc-shaped block (21) and the support column (17) are slidably installed together.

4. The autoimmune disease gene detection device according to claim 1, characterized in that: The second movable plate (9) has a second electric telescopic rod (10) fixedly installed on the top left and right sides, and the lower end of the second electric telescopic rod (10) is fixedly connected to the upper surface of the fixed plate (5).

5. The autoimmune disease gene detection device according to claim 1, characterized in that: A placement seat (14) is fixedly installed on the upper surface of the first movable plate (4), and a reagent kit (15) is placed inside the placement seat (14).

6. The autoimmune disease gene detection device according to claim 5, characterized in that: The protective strip (13) is vertically aligned with the protective frame (16), and the placement seat (14) is located inside the protective strip (13) and is aligned with the protective frame (16).

7. The autoimmune disease gene detection device according to claim 1, characterized in that: The baffle (19) is slidably sleeved with the first protective shell (6), the baffle (19) is positioned corresponding to the round hole (8), and the first movable plate (4) is located below the fixed plate (5).