Full-automatic chemiluminescence analyzer

Abstract

The utility model relates to a full-automatic chemiluminescence analyzer which comprises a rack, a bottom plate is arranged on the rack, a first guide rail penetrating through the rack is arranged on the bottom plate, a reaction module is connected to the first guide rail in a sliding mode, a reaction bin is arranged on the end face, away from the bottom plate, of the reaction module, a mounting groove is formed in the reaction bin, and a reagent strip is clamped in the reaction bin; the rack is provided with a second guide rail towards the bottom plate, the second guide rail is slidably connected with a sampling transfer module, the sampling transfer module comprises a sampling support, a pipetting assembly and a magnetic attraction assembly, the sampling support is slidably connected to the second guide rail, the pipetting assembly is connected to the sampling support, and the pipetting assembly is provided with a gun head towards the reagent strip; the magnetic attraction assembly is connected to the rack and located above the reagent strip, the sampling support is connected to one side of the magnetic attraction assembly, the other side of the magnetic attraction assembly is provided with a detection module facing the bottom plate, and the detection module is provided with a lifting structure relative to the reagent strip. The utility model aims to realize high integration of the machine body, improve the space utilization rate and avoid reagent pollution.

Description

Technical Field

[0001] This utility model relates to the field of immunoassay technology, and in particular to a fully automated chemiluminescence analyzer. Background Technology

[0002] Chemiluminescence immunoassay has become an important technique in modern clinical diagnosis due to its high sensitivity, high selectivity, and broad application prospects. In recent years, fully automated chemiluminescence analyzers have been widely used in clinical laboratories, hospitals, and other medical institutions, playing a particularly important role in early disease screening, tumor marker detection, cardiovascular disease detection, and infectious disease detection. Fully automated chemiluminescence analyzers offer advantages such as high throughput, high automation, and fast detection speed, significantly improving detection efficiency and accuracy.

[0003] Existing fully automated chemiluminescence analyzers typically use reagent kits or reagent strips for detection, but these devices have several drawbacks. First, the handling of reagent strips in existing equipment is complex, prone to inaccurate reagent addition and difficulty in reagent replacement, increasing the workload of operators. Second, while fully automated chemiluminescence analyzers achieve some degree of automation in sample and reagent processing, the lack of an effective tip management and retrieval system still poses a risk of cross-contamination, affecting the accuracy of test results. Furthermore, the devices are bulky and require limited space, making them unsuitable for small medical institutions. Utility Model Content

[0004] The main purpose of this invention is to provide a fully automated chemiluminescence analyzer, which aims to achieve a high degree of integration of the machine body, improve space utilization, and avoid reagent contamination.

[0005] To achieve the above objectives, this utility model proposes a fully automated chemiluminescence analyzer, comprising a frame, a base plate, a first guide rail passing through the frame, a reaction module slidably connected on the first guide rail, a first driving component at one end facing the reaction module, a reaction chamber at the end of the reaction module away from the base plate, a waste liquid box at the bottom edge of the reaction module away from the first driving component, and a mounting groove inside the reaction chamber for securing a reagent strip.

[0006] The frame is provided with a second guide rail facing the base plate. A sampling transfer module is slidably connected to the second guide rail. The sampling transfer module includes a sampling bracket, a pipetting assembly, and a magnetic suction assembly. The sampling bracket is slidably connected to the second guide rail and is connected to a second driving component. The pipetting assembly is connected to the sampling bracket and has a pipette tip facing the reagent strip.

[0007] The magnetic suction assembly is connected to the frame and positioned above the reagent strip. The sampling bracket is connected to one side of the magnetic suction assembly, and the other side of the magnetic suction assembly facing the base plate has a detection module. The detection module has a lifting structure relative to the reagent strip.

[0008] In one embodiment of this application, the reaction module includes a support plate and a reaction base. The support plate is slidably connected to a first guide rail. The waste liquid box is connected to the support plate and is positioned toward the reagent strip. One end of the reaction base is connected to the support plate, and the other end is connected to the reaction chamber. The reaction base is provided with a heating structure away from the reaction chamber.

[0009] The reaction chambers are provided in multiple locations, and the multiple reaction chambers are spaced apart along a direction perpendicular to the first guide rail.

[0010] In one embodiment of this application, the pipetting assembly includes a pipette and a negative pressure assembly. The pipette is connected to the end face of the sampling bracket away from the magnetic suction assembly, and the negative pressure assembly is connected to the pipette and has a pipette tip facing the reagent strip.

[0011] In one embodiment of this application, the negative pressure assembly includes a third guide rail, a cylinder, a piston rod, and a slider. The cylinder is connected to a pipette, the third guide rail is connected to the pipette in a direction perpendicular to the cylinder, the slider is slidably connected to the third guide rail and connected to a third driving member away from the cylinder, the piston rod passes through the cylinder and is provided with a sealing plug relative to the cylinder, and the slider is driven and connected to the piston rod.

[0012] In one embodiment of this application, the magnetic suction assembly includes a magnetic suction plate and a permanent magnet. The magnetic suction plate is parallel to the base plate and connected to the frame. The magnetic suction plate is provided with a fourth guide rail relative to the permanent magnet. The end of the permanent magnet away from the pipetting assembly is driven to be connected to a fourth driving member.

[0013] In one embodiment of this application, the permanent magnet is provided with a connecting structure facing the pipetting assembly, and the connecting structure is located between the reagent strip and the pipette tip.

[0014] In one embodiment of this application, the detection module includes a slider connecting block and a photon counter. The slider connecting block is connected to the side edge of the magnetic suction plate and is located above the reaction module. The photon counter is slidably connected to the slider connecting block and is connected to a lifting structure away from the bottom plate.

[0015] In one embodiment of this application, a fifth guide rail perpendicular to the first guide rail is provided on the side of the magnetic suction plate away from the pipetting assembly. A detection bracket is slidably connected to the fifth guide rail, and a fifth driving member is provided relative to the detection bracket. The detection bracket is driven to be connected to the slider connecting block.

[0016] In one embodiment of this application, the outer periphery of the frame and the base plate is covered with a shell, and the end face of the shell opposite to the first driving member is provided with an inlet and outlet opposite to the reaction module. The inlet and outlet are rotatably connected to a chamber door, the first guide rail is connected to the chamber door, and the reaction module passes through the inlet and outlet.

[0017] The outer casing is detachably connected to a controller module.

[0018] In one embodiment of this application, the silo door is rotatably connected to the bottom edge of the inlet / outlet and is provided with a torsion spring relative to the outer shell, and the reaction module is provided with a top block protruding towards the silo door.

[0019] By adopting the above technical solution, this utility model has the following advantages:

[0020] 1. The frame is mounted on the base plate. Using these two as a framework facilitates the design of the installation positions of other mechanisms. The first guide rail allows the reaction module to move back and forth with the assistance of the first drive component. A reagent strip is installed and fixed in the reaction chamber on the reaction module. The reagent strip has a TIP head mounting hole, multiple reaction grooves, and a light-shielding test groove along the direction from the pipetting assembly to the detection module. The sampling bracket and pipetting assembly are fixed to the frame via the second guide rail and can only move up and down. The first guide rail allows different grooves of the reagent strip to pass through the bottom of the pipetting assembly in sequence. The pipetting tip on the pipetting assembly punches holes in the sealing film on the grooves, allowing the TIP head structure to easily reach into the grooves to collect and transfer liquid for testing. With the help of the first guide rail, the pipetting tip punches holes in multiple reaction grooves along the direction from the detection module to the pipetting assembly in sequence. When the TIP head structure reaches the bottom of the pipetting tip, the pipetting tip connects it using a snap-fit ​​method. The TIP head structure, further enhanced by the rotating reaction module, allows the TIP head to pass sequentially through multiple reaction grooves with the aid of the pipette tip connected to the pipette assembly. This facilitates the sequential handling of the test liquid, dilution liquid, and liquid transfer. A magnetic suction component filters the liquid during the reaction process, removing useless or non-magnetic portions, thus cleaning the reagent liquid. After the TIP head completes its task, the reaction module reverses its direction. Passing through the TIP head mounting hole, the pipette assembly, in conjunction with the TIP head, separates the TIP head from the pipette tip. This allows the TIP head to be delivered along with the reagent strip from the reaction module to the bottom of the detection module for final testing. After testing, the TIP head can be retrieved together with the reagent strip. This structure achieves a high degree of integration within the instrument, improving detection efficiency and effectively saving space. This allows for a smaller analyzer, making it suitable for a wider range of applications.

[0021] 2. The reaction module has a waste liquid box at the end facing the TIP head mounting hole of the reagent strip away from the first driving component. With the help of the waste liquid box, when the TIP head structure is re-inserted into the TIP head mounting hole after testing, but before the recycling process, the waste liquid inside will be directly received by the waste liquid box, which can effectively avoid contamination. It also makes it easier to recycle the TIP head structure together with the tested reagent strip, which can effectively improve the testing efficiency.

[0022] 3. The sampling and transfer module includes a second guide rail, a sampling bracket, a pipetting assembly, and a magnetic suction assembly. The second guide rail is located between the frame and the magnetic suction assembly. The pipetting assembly can reciprocate along the vertical line in cooperation with the sampling bracket and the second guide rail. The structures of the first, second, and third driving components are similar, all of which can be a screw-motor structure. By using the screw logic with the sampling bracket, the distance of object movement can be controlled more flexibly and with higher precision. This can effectively prevent the TIP head structure from hitting the groove of the reagent strip and causing damage, thus effectively ensuring safe use. Attached Figure Description

[0023] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0024] Figure 1 This is a schematic diagram of the structure of the fully automated chemiluminescence analyzer of this utility model;

[0025] Figure 2 This is another structural schematic diagram of the fully automated chemiluminescence analyzer of this utility model;

[0026] Figure 3 This is a cross-sectional view of the fully automated chemiluminescence analyzer of this utility model;

[0027] Figure 4 This is a schematic diagram of the frame structure of the fully automated chemiluminescence analyzer of this utility model from one perspective;

[0028] Figure 5 This is a schematic diagram of the frame structure of the fully automated chemiluminescence analyzer of this utility model from another perspective;

[0029] Figure 6 This is a schematic diagram of the pipetting assembly of the fully automated chemiluminescence analyzer of this utility model;

[0030] Figure 7 This is a cross-sectional view of the pipetting assembly of the fully automated chemiluminescence analyzer of this invention.

[0031] Explanation of icon numbers:

[0032] 1. Frame; 11. Base plate; 12. First guide rail; 13. Second guide rail; 2. Reaction module; 21. Support plate; 22. Waste liquid box; 23. Reaction base; 24. Reaction chamber; 3. Reagent strip; 4. Sampling and transfer module; 41. Sampling bracket; 5. Pipette assembly; 51. Pipette plate; 52. Negative pressure assembly; 6. Magnetic suction assembly; 61. Magnetic suction plate; 62. Permanent magnet; 7. Detection module; 71. Fifth guide rail; 72. Detection bracket; 73. Slider connecting block; 74. Photon counter; 8. Outer shell; 81. Chamber door; 9. Controller module.

[0033] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0034] To make the objectives, technical solutions, and advantages of this application clearer, the following detailed description is provided in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application.

[0035] Reference Figures 1 to 7 To achieve the above objectives, this utility model proposes a fully automated chemiluminescence analyzer, including a frame 1, a base plate 11, a first guide rail 12 passing through the frame 1, a reaction module 2 slidably connected on the first guide rail 12, and a first driving component at one end facing the reaction module 2. The reaction module 2 has a reaction chamber 24 on the end face away from the base plate 11, and a waste liquid box 22 is provided on the bottom edge of the reaction module 2 away from the first driving component. The reaction chamber 24 has an installation groove and a reagent strip 3 is snapped into place.

[0036] The frame 1 is provided with a second guide rail 13 facing the base plate 11. A sampling transfer module 4 is slidably connected to the second guide rail 13. The sampling transfer module 4 includes a sampling bracket 41, a pipetting assembly 5, and a magnetic suction assembly 6. The sampling bracket 41 is slidably connected to the second guide rail 13 and is connected to a second driving component. The pipetting assembly 5 is connected to the sampling bracket 41 and has a pipette tip facing the reagent strip 3.

[0037] The magnetic suction assembly 6 is connected to the frame 1 and is located above the reagent strip 3. The sampling bracket 41 is connected to one side of the magnetic suction assembly 6. The other side of the magnetic suction assembly 6 facing the base plate 11 is provided with a detection module 7. The detection module 7 is provided with a lifting structure relative to the reagent strip 3.

[0038] The frame 1 is mounted on the base plate 11. Using these two as a framework facilitates the design of the installation positions of other mechanisms. The first guide rail 12 allows the reaction module 2 to move back and forth with the help of the first driving component. The reaction chamber 24 on the reaction module 2 contains a reagent strip 3. The reagent strip 3 has a TIP head mounting hole, multiple reaction grooves, and a light-shielding test groove along the direction from the pipetting assembly 5 to the detection module 7. The sampling bracket 41 and the pipetting assembly 5 are fixed to the frame 1 by the second guide rail 13 and can only move up and down. The first guide rail 12 allows the different grooves of the reagent strip 3 to pass through the bottom of the pipetting assembly 5 in sequence. The pipette tip on the pipetting assembly 5 punches holes in the sealing film on the grooves, allowing the TIP head structure to easily reach into the grooves to collect and transfer liquid for testing. With the help of the first guide rail 12, the pipette tip punches holes in multiple reaction grooves along the direction from the detection module 7 to the pipetting assembly 5 in sequence. When the TIP head structure reaches the bottom of the pipette tip, the pipette tip... The TIP head structure is connected via a snap-fit ​​mechanism. Furthermore, the reaction module 2 rotates and moves, allowing the TIP head structure to sequentially pass through multiple reaction grooves with the aid of the pipette tip connected to the pipette assembly 5. This facilitates the sequential handling of multiple steps, including taking the test liquid, diluting the liquid, and transferring the liquid. The magnetic suction assembly 6 can be used to screen the liquid during the reaction process, removing useless or non-magnetic portions, thus achieving the purpose of cleaning the reagent liquid. After the TIP head structure completes its task, the reaction module 2 moves in the opposite direction again. When passing through the TIP head mounting hole, the TIP head structure can be separated from the pipette tip with the assistance of the pipette assembly 5. This allows the TIP head to be delivered along with the reagent strip 3 from the reaction module 2 to the bottom of the detection module 7 for final testing. After testing, the TIP head can be recovered together with the reagent strip. This structure achieves a high degree of integration of the internal structure, improving detection efficiency and effectively saving space, allowing for a smaller analyzer that can be applied to more scenarios.

[0039] The reaction module 2, facing away from the first driving component, has a waste liquid box 22 at the TIP head mounting hole of the reagent strip 3. With the help of the waste liquid box 22, when the TIP head structure is re-inserted into the TIP head mounting hole after testing, but before the recycling process, the waste liquid inside will be directly received by the waste liquid box 22, which can effectively avoid contamination. It also makes it easier to recycle the TIP head structure together with the tested reagent strip 3, which can effectively improve the testing efficiency.

[0040] The sampling transfer module 4 includes a second guide rail 13, a sampling bracket 41, a pipetting assembly 5, and a magnetic suction assembly 6. The second guide rail 13 is located between the frame 1 and the magnetic suction assembly 6. The pipetting assembly 5 can reciprocate along the vertical line with the cooperation of the sampling bracket 41 and the second guide rail 13. The structures of the first, second, and third driving components are generally similar, and they can all be a structure of lead screw and motor. The lead screw is screwed to the sampling bracket 41, which can more flexibly and with high precision control the distance of the object movement. It can effectively avoid the TIP head structure hitting the groove of the reagent strip 3 and causing damage, and can effectively ensure the safety of use.

[0041] See also Figure 4 The reaction module 2 includes a support plate 21 and a reaction base 23. The support plate 21 is slidably connected to the first guide rail 12. The waste liquid box 22 is connected to the support plate 21 and is positioned towards the reagent strip 3. One end of the reaction base 23 is connected to the support plate 21 and the other end is connected to the reaction chamber 24. The reaction base 23 is provided with a heating structure away from the reaction chamber 24. There are multiple reaction chambers 24, which are spaced apart along a direction perpendicular to the first guide rail 12.

[0042] The support plate 21 can move the reaction base 23 away from the base plate 11, making it easier for the heating structure, such as the heating film, installed at the bottom of the reaction base plate 11 to be heated. At the same time, the support plate 21 can make the reaction chamber 24 higher, so that when the TIP head structure is inserted into the TIP head mounting hole, the TIP head structure can be suspended relative to the waste liquid box 22, avoiding damage to the TIP head structure. The extension direction of the reaction chamber 24 is set along the extension direction of the first guide rail 12. The reagent strip 3 is inserted into the reaction chamber 24. Multiple reaction chambers 24 are spaced apart along the direction perpendicular to the first guide rail 12, so that the analyzer can test multiple reagent strips 3 at the same time to improve the testing efficiency.

[0043] See also Figures 4 to 7 The pipetting assembly 5 includes a pipetting plate 51 and a negative pressure assembly 52. ​​The pipetting plate 51 is connected to the end face of the sampling bracket 41 away from the magnetic suction assembly 6. The negative pressure assembly 52 is connected to the pipetting plate 51 and has a pipette tip facing the reagent strip 3.

[0044] The pipette 51 is connected to the sampling bracket 41 and together with the sampling bracket 41 completely covers the second guide rail 13. This structure can effectively ensure the stability of the moving track of the pipette assembly 5, effectively ensure the stable gripping of the TIP head structure by the pipette tip, and ensure the moving trajectory of the TIP head structure. The negative pressure assembly 52 is used to generate negative pressure. Through the cooperation of the pipette tip and the TIP head structure, it can achieve the effect of stabilizing the TIP head structure to aspirate and transfer liquid, and effectively prevent liquid leakage caused by the shaking of the TIP head structure, thus effectively preventing contamination.

[0045] Furthermore, to facilitate the automatic removal of the TIP head structure from the gun head, combined with Figure 6 and Figure 7 As can be seen in one feasible embodiment, a push plate is also provided below the pipetting assembly 5. Guide posts are provided on both sides of the push plate. The guide posts pass through both sides of the cylinder body and are fixedly connected to the push plate. The guide posts are also slidably connected to the cylinder body. A spring is sleeved on the other end of the guide post. A limit block is provided at the top of the guide post. The spring is located between the limit block and the cylinder body. Through this structure, before the limit block is subjected to any additional force other than the weight of the entire mechanism and the elastic force of the spring, the limit block can keep the push plate in contact with the bottom surface of the cylinder body under the action of the spring force. The push plate is also provided with a through hole adapted to the pipette tip. This through hole is clearance-fitted with the pipette tip, and the pipette tip can pass freely through the through hole. In addition, after the TIP head structure is picked up, the end face of the TIP head structure is in contact with the bottom surface of the push plate to ensure that the TIP head structure is locked more securely. After the experiment is completed, the TIP head structure needs to be retracted back into the TIP head mounting hole of reagent strip 3. Driven by the third drive unit, the slider moves downward, causing the piston rod to move downward as well. This creates a positive pressure on the liquid inside the TIP head, squeezing the liquid into the corresponding groove of reagent strip 3. As the piston rod continues to move downward, all the liquid inside the TIP head is squeezed out. When the slider exceeds the normal cyclic movement range, it continues to push the piston rod downward under the drive of the lead screw. At this time, the two ends of the slider apply a downward pressure to the limit block and spring, causing the push plate to move downward, thus automatically pushing the TIP head structure off the pipette tip. This pipette assembly can perform actions such as reagent aspiration, transfer, and cleaning, while also picking up and unloading the TIP head structure and automatically puncturing the heat-sealed aluminum film of reagent strip 3. This integrates multiple functions into one mechanism, greatly saving equipment space, reducing costs, and improving production efficiency.

[0046] See also Figures 6 to 7 The negative pressure assembly 52 includes a third guide rail, a cylinder, a piston rod, and a slider. The cylinder is connected to the pipette 51. The third guide rail is connected to the pipette 51 in a direction perpendicular to the cylinder. The slider is slidably connected to the third guide rail and is connected to a third driving member away from the cylinder. The piston rod passes through the cylinder and is provided with a sealing plug relative to the cylinder. The slider is driven and connected to the piston rod.

[0047] The slider is slidably mounted on the pipette 51 in the vertical direction via the third guide rail structure. The output end of the third drive unit is connected to the slider to drive the slider to slide in the vertical direction. The piston rod is slidably connected to the cylinder in the vertical direction. The top of the piston rod is exposed outside the cylinder and connected to the slider. A sealing ring that fits tightly with the piston rod is provided inside the cylinder. The third drive unit drives the slider to move upward, which can pull the piston rod, thereby forming a negative pressure cavity between the piston rod and the cylinder, thus realizing liquid aspiration. The lead screw can ensure the aspiration accuracy and efficiency.

[0048] See also Figures 3 to 5 The magnetic suction assembly 6 includes a magnetic suction plate 61 and a permanent magnet 62. The magnetic suction plate 61 is parallel to the base plate 11 and connected to the frame 1. The magnetic suction plate 61 is provided with a fourth guide rail relative to the permanent magnet 62. The end of the permanent magnet 62 facing away from the pipetting assembly 5 is driven to be connected to a fourth driving component.

[0049] The magnetic suction assembly 6 includes a permanent magnet 62 and a magnetic suction plate 61. The permanent magnet 62 is parallel to the first guide rail 12 via a fourth guide rail structure and is slidably mounted on the magnetic suction plate 61. The magnetic suction plate 61 is fixedly connected to the frame 1, and the sampling bracket 41 is fixed to the front of the magnetic suction plate 61. The permanent magnet 62 is fixed to the back of the magnetic suction plate 61. A fourth driving component is also provided on the back of the magnetic suction plate 61. The fourth driving component can drive the permanent magnet 62 to move along the fourth guide rail toward the pipetting assembly 5 and engage with the TIP tip, thereby adsorbing magnetic beads in the reagent when the TIP tip picks up the reaction reagent, and then discharging the reaction reagent without magnetic beads through the piston rod and cylinder structure to achieve a cleaning effect.

[0050] See also Figure 4 The permanent magnet 62 is provided with a connecting structure facing the pipetting assembly 5, and the connecting structure is located between the reagent strip 3 and the pipette tip.

[0051] In this application, the connecting structure is provided with a permanent magnet 62 away from the pipetting assembly 5. By utilizing the connecting structure, the permanent magnet 62 can cover a larger area of ​​the TIP head structure, which can effectively improve the cleaning effect.

[0052] See also Figure 5 The detection module 7 includes a slider connecting block 73 and a photon counter 74. The slider connecting block 73 is connected to the side edge of the magnetic suction plate 61 and is located above the reaction module 2. The photon counter 74 is slidably connected to the slider connecting block 73. The photon counter 74 is connected to a lifting structure away from the base plate 11.

[0053] The slider connecting block 73 is provided with a guide rail that moves and limits the photon counter 74 up and down, and is also connected to a lifting structure relative to the photon counter 74. Using this structure, when the light-shielding test slot on the reagent strip 3 is directly below it, the photon counter 74 will move down and be sealed and locked into the light-shielding test slot, which can effectively improve the detection efficiency.

[0054] See also Figure 5 The magnetic suction plate 61 is provided with a fifth guide rail 71 perpendicular to the first guide rail 12 on the side away from the pipetting assembly 5. A detection bracket 72 is slidably connected on the fifth guide rail 71, and a fifth driving member is provided relative to the detection bracket 72. The detection bracket 72 is driven to be connected to the slider connecting block 73.

[0055] Because there are multiple reaction chambers 24 and multiple reagent strips 3, in order to test multiple reagent strips 3 in different positions, the detection module 7 also includes a detection bracket 72 and a fifth guide rail 71. The slider connecting block 73 is fixed on the detection bracket 72. With the help of the fifth guide rail 71 and the upgraded structure, even if the photon counter 74 has only a single test probe, it can successfully detect multiple reagent strips 3.

[0056] See also Figures 1 to 3 The outer periphery of the frame 1 and the base plate 11 is covered by a shell 8. The end face of the shell 8 facing away from the first drive component is provided with an inlet and outlet opposite to the reaction module 2. The inlet and outlet are rotatably connected to a chamber door 81. The first guide rail 12 is connected to the chamber door 81. The reaction module 2 passes through the inlet and outlet. The shell 8 is detachably connected to a controller module 9.

[0057] The outer casing 8 can protect the internal components, and the inlet and outlet ports can facilitate the free entry and exit of the reaction module 2 and the loading and unloading of reagent strips 3. The inlet and outlet door 81 can be a door structure that is automatically controlled by the controller module 9. The controller module 9 itself can be disassembled, and one controller module 9 can control one or more chemiluminescence analyzers using network cable, WiFi, Bluetooth, etc., which can effectively improve the user experience.

[0058] See also Figure 3 The silo door 81 is rotatably connected to the bottom edge of the inlet and outlet, and is provided with a torsion spring relative to the outer shell 8. The reaction module 2 is provided with a top block protruding towards the silo door 81.

[0059] In this application, when the chamber door 81 is installed and the machine is not in operation, it can firmly seal the inlet and outlet ports with the help of a torsion spring. The bottom edge of the reaction module 2 is provided with a top block. Using the top block, the chamber door 81 can be automatically opened when the reaction module 2 moves toward the chamber door 81. At this time, the reagent strip 3 can be removed from or installed on the reaction module 2. Driven by the motor, the reaction module 2 can slide inward along the first guide rail 12 until the chamber door 81 is completely closed under the torque of the torsion spring. The chamber door 81 can be automatically opened and closed without manual operation, which can effectively improve the user experience.

[0060] In the accompanying drawings of this embodiment, the same or similar reference numerals correspond to the same or similar components. In the description of this application, it should be understood that if terms such as "upper," "lower," "left," and "right" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, they are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the terms used to describe positional relationships in the accompanying drawings are only for illustrative purposes and should not be construed as limiting this patent. For those skilled in the art, the specific meaning of the above terms can be understood according to the specific circumstances.

[0061] The above are merely preferred embodiments of this application and are not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A fully automated chemiluminescence analyzer comprising a machine frame, characterized in that, The rack is provided with a bottom plate, the bottom plate is provided with a first guide rail penetrating the rack, a reaction module is slidably connected to the first guide rail, a first driving element is arranged at one end of the reaction module, an end face of the reaction module away from the bottom plate is provided with a reaction chamber, a waste liquid box is arranged at the bottom edge of the reaction module away from the first driving element, an installation groove is arranged in the reaction chamber, and a reagent strip is clamped in the installation groove; The rack is provided with a second guide rail facing the bottom plate, a sampling transfer module is slidably connected to the second guide rail, the sampling transfer module comprises a sampling support, a pipetting assembly and a magnetic assembly, the sampling support is slidably connected to the second guide rail and is connected with a second driving element, the pipetting assembly is connected to the sampling support, and a gun head is arranged on the pipetting assembly facing the reagent strip; The magnetic assembly is connected to the rack and is above the reagent strip, one side of the sampling support is connected to the magnetic assembly, and a detection module is arranged on the other side of the magnetic assembly facing the bottom plate, and the detection module is provided with a lifting structure relative to the reagent strip.

2. The fully automated chemiluminescence analyzer according to claim 1, wherein The reaction module comprises a support plate and a reaction base, the support plate is slidably connected to the first guide rail, the waste liquid box is connected to the support plate and is arranged facing the reagent strip, one end of the reaction base is connected to the support plate, and the other end of the reaction base is connected to the reaction chamber, and the reaction base is provided with a heating structure away from the reaction chamber; The reaction chamber is provided with a plurality of reaction chambers, and the plurality of reaction chambers are arranged in a spaced manner along a direction perpendicular to the first guide rail.

3. The fully automated chemiluminescence analyzer according to claim 1, wherein The pipetting assembly comprises a pipetting plate and a negative pressure assembly, the pipetting plate is connected to an end face of the sampling support away from the magnetic assembly, and the negative pressure assembly is connected to the pipetting plate and is provided with a gun head facing the reagent strip.

4. The fully automated chemiluminescence analyzer according to claim 3, wherein The negative pressure assembly comprises a third guide rail, a cylinder body, a piston rod, and a sliding block, the cylinder body is connected to the pipetting plate, the third guide rail is connected to the pipetting plate along a direction perpendicular to the cylinder body, the sliding block is slidably connected to the third guide rail and is connected with a third driving element away from the cylinder body, the piston rod penetrates the cylinder body and is provided with a sealing plug relative to the cylinder body, and the sliding block is drivingly connected to the piston rod.

5. The fully automated chemiluminescence analyzer according to claim 1, wherein The magnetic assembly comprises a magnetic plate and a permanent magnet, the magnetic plate is parallel to the bottom plate and is connected to the rack, the magnetic plate is provided with a fourth guide rail relative to the permanent magnet, and one end of the permanent magnet away from the pipetting assembly is drivingly connected with a fourth driving element.

6. The fully automated chemiluminescence analyzer according to claim 5, wherein The permanent magnet is provided with a connecting structure facing the pipetting assembly, and the connecting structure is between the reagent strip and the gun head.

7. The fully automated chemiluminescence analyzer according to claim 5, wherein The detection module comprises a sliding block connecting block and a photon counter, the sliding block connecting block is connected to a side edge of the magnetic plate and is above the reaction module, the photon counter is slidably connected to the sliding block connecting block, and the photon counter is connected with a lifting structure away from the bottom plate.

8. The fully automated chemiluminescence analyzer according to claim 7, wherein One side of the magnetic plate away from the pipetting assembly is provided with a fifth guide rail perpendicular to the first guide rail, a detection support is slidably connected to the fifth guide rail and is provided with a fifth driving element relative to the detection support, and the detection support is drivingly connected to the sliding block connecting block.

9. The fully automated chemiluminescence analyzer according to claim 1, wherein The outer periphery of the rack and the bottom plate is covered with an outer shell, an end face of the outer shell away from the first driving element is provided with an inlet and outlet opening relative to the reaction module, the inlet and outlet opening is rotatably connected with a chamber door, the first guide rail is connected to the chamber door, and the reaction module penetrates the inlet and outlet opening; The outer shell is detachably connected with a controller module.

10. The fully automated chemiluminescence analyzer according to claim 9, wherein The door is rotatably connected to the bottom edge of the inlet and outlet, and is provided with a torsion spring relative to the shell, and the reaction module protrudes a top block towards the door.

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