Detection device, detection method thereof and reagent strip storage reactor

Abstract

The application discloses a detection device, a detection method thereof and a reagent strip storage reactor, wherein the detection device comprises a shell, a reagent strip storage reactor is arranged in the shell, the reagent strip storage reactor comprises a carrier plate, a rocking bed is arranged on the carrier plate, a first fixing device for fixing a reagent strip tray on the rocking bed is arranged on the rocking bed, and a releasing device for driving the first fixing device to release the fixation of the reagent strip tray on the rocking bed is further arranged on the carrier plate, and the releasing device is detachably connected with the first fixing device. The reagent strip can be shaken by the rocking bed, the reagent strip in shaking can make the reaction more efficient and sufficient, and the detection efficiency and the detection precision are improved. The releasing device and the first fixing device are detachably connected, when the rocking bed needs to shake, the releasing device is separated from the first fixing device, so that the releasing device is prevented from shaking with the rocking bed, the load of the rocking bed is reduced, and the structural stability of the releasing device is ensured.

Description

Technical Field

[0001] This invention relates to the field of medical devices, and in particular to a detection device, a detection method thereof, and a reagent strip storage reactor capable of performing immunoassays using reagent strips. Background Technology

[0002] Fluorescent immunoassay is a highly sensitive fluorescent immunoassay that enhances the intensity of fluorescence signals through certain methods, thereby enabling the detection of low-concentration targets.

[0003] Patent document CN112782415B discloses a pretreatment device for fluorescence immunoassay.

[0004] In this device, the reagent strip remains stationary when the probe is immersed into different wells of the reagent strip, which limits the improvement of reaction efficiency. Summary of the Invention

[0005] The purpose of this invention is to solve the above-mentioned problems existing in the prior art and to provide a detection device, its detection method and reagent strip storage reactor.

[0006] The objective of this invention is achieved through the following technical solution:

[0007] The testing device includes a housing, within which a reagent strip storage reactor is disposed. The reagent strip storage reactor includes a carrier plate, on which a shaker is disposed. The shaker is provided with a first fixing device for fixing a reagent strip tray on the shaker by a fixing claw. The carrier plate is also provided with a releasing device for driving the first fixing device to release the fixing of the reagent strip tray on the shaker. The releasing device is detachably connected to the first fixing device. When the releasing device is separated from the first fixing device, the first fixing device fixes the reagent strip tray on the shaker.

[0008] Preferably, the first fixing device includes a set of fixing claws that move and open / close at least along a second horizontal direction, the second horizontal direction being perpendicular to a first horizontal direction, the first horizontal direction being defined as the length direction of the platform of the shaking bed, an elastic element is provided between each fixing claw and the platform of the shaking bed to keep the fixing claw in a fixed position, and each fixing claw is provided with a release passive element for being detachably connected to the release device below the platform.

[0009] Preferably, the release device includes a release block, which is provided with a release driving surface corresponding to each of the release passive members. The release block is connected to a release driving mechanism that drives it to move up and down. During the upward movement of the release block, the release driving surface drives the release passive member to move away from the platform so that the plurality of fixing claws open.

[0010] Preferably, the carrier plate is provided with rotatable limiting gears on both sides, and the housing is provided with limiting racks that can be separably meshed with each of the limiting gears. The limiting racks extend along a first horizontal direction, and when the shaking table is located inside the housing, the limiting gear on each side meshes with the limiting rack on its corresponding side.

[0011] Preferably, the shaking bed is disposed on the top of the carrier plate and located at the outer end of the carrier plate. The shaking bed can be moved from inside the housing to outside the housing. The outer end of the carrier plate is provided with a first compartment door, and the inner side of the first compartment door is hinged to the carrier plate.

[0012] Preferably, the outer shell is provided with a material storage component located next to the reagent strip storage reactor, the outer shell is provided with a second compartment door corresponding to the material storage component, the material storage component is disposed on a rotating mechanism that drives its rotation, and the rotating mechanism is provided with a second fixing device for fixing the material storage component on the rotating mechanism.

[0013] Preferably, the material storage assembly includes a storage tank and a material storage device detachably disposed above the storage tank, wherein the material storage device is provided with a waste recycling channel communicating with the storage tank.

[0014] Preferably, the second fixing device includes a sample tube holder, and a cap-removing mechanism is provided inside the housing next to the material storage component. The cap-removing mechanism removes the cap by having a cap-removing needle pass horizontally through the cap on the sample tube and move upward.

[0015] Preferably, the top of the material storage assembly is provided with a centrifuge tube storage position, and the outer shell is also provided with a centrifugation mechanism.

[0016] A reagent strip storage reactor includes a carrier plate, on which a shaker is mounted. A first fixing device is mounted on the shaker to fix a reagent strip tray on the shaker via a fixing claw. The carrier plate also includes a release device that drives the first fixing device to release the reagent strip tray from the shaker. The release device is detachably connected to the first fixing device. When the release device is separated from the first fixing device, the first fixing device fixes the reagent strip tray on the shaker.

[0017] The detection method based on any of the detection devices described above includes the following steps:

[0018] Move the shaker outside the casing;

[0019] The retaining claw of the first fixing device is opened by the release device;

[0020] Place the reagent strip tray containing the reagent strips on the shaker, and separate the release device from the first fixing device so that the fixing claw closes to fix the reagent strip tray on the shaker.

[0021] Move the shaker into the housing.

[0022] The advantages of the technical solution of this invention are mainly reflected in:

[0023] This invention incorporates a shaker within a reagent strip storage reactor. During testing, the shaker drives the reagent strip to vibrate. Compared to a stationary reagent strip, a vibrating reagent strip allows for a more efficient and complete reaction, improving detection efficiency and accuracy. Furthermore, a detachable release device works in conjunction with a first fixing device. When the shaker needs to vibrate, the release device separates from the first fixing device, preventing it from vibrating with the shaker. This reduces the load on the shaker and ensures the structural stability of the release device.

[0024] The first compartment door of the present invention is mounted on the carrier plate and hinged to the carrier plate, and can automatically open and close the first compartment door when the carrier plate moves, without the need for manual operation. At the same time, when the first compartment door is open, it can rotate downward relative to the carrier plate to avoid it, thereby facilitating manual operation and effectively improving the convenience of operation.

[0025] The present invention incorporates a centrifugation mechanism that allows for the centrifugation of samples before the reaction, facilitating the classification and extraction of different components and thereby improving the accuracy of detection.

[0026] The cap removal mechanism of the present invention can automatically remove the cap in conjunction with the sample tube holder, and uses a cap removal needle to insert into the cap, thereby completing the cap removal operation more reliably. Attached Figure Description

[0027] Figure 1 This is a perspective view of the detection device of the present invention;

[0028] Figure 2 This is a perspective view of the detection device of the present invention with the outer casing removed;

[0029] Figure 3 This is a perspective view of the reagent strip storage reactor, reading assembly, and reagent strip processing mechanism areas in the detection device of the present invention;

[0030] Figure 4This is a first-view perspective perspective view of the reagent strip storage reactor of the present invention;

[0031] Figure 5 This is a second-view perspective perspective view of the reagent strip storage reactor of the present invention;

[0032] Figure 6 This is a side view of the reagent strip storage reactor of the present invention;

[0033] Figure 7 This is a side sectional view of the reagent strip storage reactor of the present invention;

[0034] Figure 8 yes Figure 5 A magnified view of a portion of the image;

[0035] Figure 9 This is an end cross-sectional view of the reagent strip storage reactor of the present invention;

[0036] Figure 10 This is a perspective view of the material storage component, rotating mechanism, and second fixing mechanism of the present invention;

[0037] Figure 11 This is an exploded view of the material storage component of the present invention;

[0038] Figure 12 This is a perspective view of the material storage assembly, rotating mechanism and second fixing mechanism provided with a cover in the third storage position of the present invention;

[0039] Figure 13 This is a side view of the material storage component of the present invention;

[0040] Figure 14 This is a partial schematic diagram of the cap-removing mechanism of the present invention;

[0041] Figure 15 This is a perspective view of the cap-removing mechanism of the present invention;

[0042] Figure 16 This is a side view of the material storage assembly, rotating mechanism, and second fixing mechanism of the present invention;

[0043] Figure 17 This is a cross-sectional view of the centrifuge mechanism of the present invention;

[0044] Figure 18 This is a perspective view of the centrifuge mechanism of the present invention;

[0045] Figure 19 This is a partial front view of the reagent strip processing mechanism of the present invention;

[0046] Figure 20 This is a partial perspective view of the reagent strip processing mechanism of the present invention;

[0047] Figure 21 This is a bottom cross-sectional view of the processing component of the present invention;

[0048] Figure 22 This is a side view of the processing component of the present invention;

[0049] Figure 23 This is a perspective view of the sample consumable transfer mechanism of the present invention;

[0050] Figure 24 This is a side view of the pipette of the present invention;

[0051] Figure 25 This is a cross-sectional view of the pipette of the present invention. Detailed Implementation

[0052] The objectives, advantages, and features of this invention will be illustrated and explained through the following non-limiting description of preferred embodiments. These embodiments are merely typical examples of applying the technical solutions of this invention, and all technical solutions formed by equivalent substitutions or equivalent transformations fall within the scope of protection claimed by this invention.

[0053] In the description of the solution, it should be noted that the terms "center," "upper," "lower," "left," "right," "front," "rear," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience and simplification of description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. Example 1

[0054] The detection device disclosed in this invention will now be described in conjunction with the accompanying drawings, as shown below. Figure 1 -Appendix Figure 4 As shown, it includes a housing 100, a base inside the housing 100, a reagent strip storage reactor 200 on the base, a carrier plate 201, a shaker 202 on the carrier plate 201, a first fixing device 203 on the shaker 202 for fixing a reagent strip tray 300 on the shaker 202 by fixing claws 204, and a release device 205 on the carrier plate 201 for driving the first fixing device 203 to release the fixing of the reagent strip tray 300 on the stage 211. The release device 205 is detachably connected to the first fixing device 203. When the release device 205 is separated from the first fixing device 203, the multiple fixing claws 204 of the first fixing device 203 close to fix the reagent strip tray 300 positioned on the shaker 202.

[0055] In one embodiment, as shown in the appendix Figure 1 -Appendix Figure 3 As shown, the carrier plate 201 can be fixed inside the outer shell 100 and near the first doorway (not shown in the figure) on the side of the outer shell 100. A first compartment door 101 is provided at the first doorway. At this time, after opening the first compartment door 101, the reagent strip 303 can be placed on the reagent strip tray 300 on the shaker 202 through the first doorway, or the reagent strip tray can be replaced directly.

[0056] It is obviously inconvenient to load and unload reagent strips 303 inside the housing 100. Therefore, in order to facilitate the loading and unloading of reagent strips 303, the carrier plate 201 is movable inside the housing 100 along the first horizontal direction X. The first horizontal direction X is defined as the length direction of the carrier plate, and the horizontal direction perpendicular to the first horizontal direction X is defined as the second horizontal direction Y.

[0057] As attached Figure 3 As shown, the carrier plate 201 is movably mounted on a first guide rail 206 inside the housing 100 via a first slider. The first guide rail 206 extends along a first horizontal direction and is mounted on a base. Simultaneously, the outer end of the carrier plate 201 can move to the outside of the housing 100. Correspondingly, the shaker 202 is mounted on the carrier plate 201 and close to its outer end, allowing the shaker to follow the carrier plate from inside the housing 100 through the first opening to the outside. At this time, the loading and unloading of reagent strips 303 can be performed outside the housing 100. Furthermore, to allow the shaker to be completely moved outside the housing, the base is movably mounted on a bottom guide rail (not shown) on the base along a first horizontal direction. Additionally, baffles are provided at both ends of the first guide rail 206. When the first slider abuts against the inner side of one of the baffles, it can move the base.

[0058] In addition, to reduce additional door opening actions, the first compartment door 101 can be located at the outer end of the carrier plate 201. Therefore, when the carrier plate 201 moves outward from the outer shell 100, the first compartment door 101 can be automatically opened, and when the carrier plate 201 moves inward from the outer shell 100, the first compartment door 101 can be automatically closed.

[0059] Furthermore, since the top of the first door 101 is higher than the carrier plate 201 and will obstruct the front of the shaking table 202, in order to reduce the interference of the first door 101 with the loading and unloading operations, the inner side of the first door 101 is hinged to the outer end of the carrier plate 201. When the shaking table 202 moves outside the housing 100, the first door 101 can rotate downward under the action of gravity, reducing its top height and increasing the distance between it and the outer end of the carrier plate 201, thereby reducing interference with manual operation.

[0060] The movement of the carrier plate 201 can be achieved by manually pushing or pulling the first compartment door 101. In a more preferred embodiment, as shown in the attached... Figure 3 As shown, the carrier plate 201 is connected to a first drive mechanism 207 that drives it to reciprocate along the first guide rail 206. The first drive mechanism 207 can be of various feasible structures, such as a servo linear module or a structure composed of a motor and a ball screw. In this embodiment, the first drive mechanism 207 uses a motor and a synchronous belt mechanism to drive the carrier plate 201 to translate. The synchronous belt mechanism includes two first pulleys 209 distributed along the first horizontal direction X and close to both ends of the carrier plate. The axes of the two first pulleys 209 extend along the second horizontal direction Y, and a first synchronous belt 210 is fitted on the two first pulleys. At this time, one first pulley can be connected to a first motor 208 that drives its rotation, and the other first pulley can be rotatably disposed inside the housing 100. Of course, in other embodiments, a drive wheel (not shown in the figure) and a steering wheel (not shown in the figure) can also be provided. In this case, two first pulleys are rotatably arranged inside the housing 100. The drive wheel is connected to the inner side of the first synchronous belt and connected to the first motor 208 that drives its rotation. The steering wheel is attached to the outer side of the first synchronous belt and close to the steering wheel. The steering wheel causes the first synchronous belt to bend upward locally and maintain a more stable connection with the drive wheel.

[0061] The shaker 202 can adopt a known feasible structure, as shown in the attached figure in this embodiment. Figure 5 As shown, the shaker 202 includes a stage 211, which is used to support and position the reagent strip tray 300. The shape of the stage 211 can be designed as needed and is not limited here.

[0062] As attached Figure 6 As shown, the bottom of the platform 211 is movably mounted on the second guide rail 213 via the second slider 212. The second guide rail 213 extends along the first horizontal direction X and is mounted on the top of the movable plate 214. The bottom of the movable plate 214 is movably mounted on the third guide rail 216 via the third slider 215. The third guide rail 216 extends along the second horizontal direction Y and is fixed on the platform 201.

[0063] As attached Figure 7 As shown, the platform 211 is also connected to a second drive mechanism 217 that drives its swaying. The second drive mechanism 217 includes a second motor 218 disposed at the bottom of the carrier plate 201. The power output shaft of the second motor passes through a through hole on the carrier plate 201 and is connected to a first eccentric shaft 219. The first eccentric shaft 219 includes a first shaft segment 220 coaxial with the power output shaft and a second shaft segment 221 eccentrically distributed with respect to the first shaft segment 220. A roller 222 is coaxially connected above and on the second shaft segment 221. The roller 222 can be a bearing or bushing, etc., which is not limited here. The roller 222 is disposed in an embedded hole 223 at the bottom of the platform 211. Thus, when the second motor 218 drives the first eccentric shaft 219 to rotate, the roller 222 rotates around the first shaft segment 220, thereby causing the platform 211 to sway.

[0064] As attached Figure 3 Appendix Figure 4 As shown, to prevent the carrier plate from shaking during the operation of the shaker, limiting gears 240 are provided on the top surface of the carrier plate on its two long sides. The axis of each limiting gear 240 extends vertically and can be separably engaged with a limiting rack 241 fixed in the housing. The limiting rack 241 extends in a first horizontal direction. When the carrier plate is inside the housing, the limiting gears 240 and the limiting rack 241 engage, thereby limiting the carrier plate in a second horizontal direction. When the shaker moves outside the housing, the limiting gears 240 and the limiting rack 241 separate, which shortens the length of the limiting rack 241 and improves support.

[0065] As attached Figure 4 Appendix Figure 7 As shown, the first fixing device 203 includes at least two horizontally movable fixing claws 204. The fixing claws 204 are preferably two and distributed on the two long sides of the platform 211. They move and open and close along the second horizontal direction Y. Of course, in some embodiments, the number of fixing claws can also be three or four. When the number of fixing claws is three, one of them can move and open and close along the first horizontal direction.

[0066] The better ones are as follows: Figure 7 Appendix Figure 8As shown, the fixing claw 204 includes a generally L-shaped body. The body includes a first portion 225 movably disposed at the bottom of the stage 211 along a second horizontal direction, and a second portion 226 located on one side of the stage 211 in the width direction. The second portion 226 extends above the bearing surface of the stage 211. Notches 227 are provided on the long side of the stage 211 for the second portion 226 to be inserted. Thus, when limiting protrusions 228 are provided around the bearing surface of the stage 211, the second portion 226 can move into the notches 227 to fix the reagent strip tray 300 located within the limiting protrusions 228. Of course, the notches 227 and the limiting protrusions 228 are not essential and can be omitted. Simultaneously, the long side of the reagent strip tray 300 can protrude beyond the side of the stage 211.

[0067] As attached Figure 8 As shown, the top of the second part 226 has a pressing part 229 protruding towards the stage 211. Simultaneously, a recessed fixing opening 301 is provided on the long side of the reagent strip tray 300. The pressing part 229 extends into the fixing opening 301, and its lower surface 230 presses against the bottom surface of the fixing opening 301, thereby fixing the reagent strip tray 300. Of course, the fixing opening 301 is not mandatory; the pressing part 229 can directly adhere to or press against the top of the long side of the reagent strip tray 300. More preferably, the lower surface 230 of the pressing part 229 is an inclined surface, and the opposite ends of the two lower surfaces 230 of the two pressing parts 229 are higher than the other end. When the pressing part presses the reagent strip tray, the opposite ends of the two lower surfaces 230 of the two pressing parts 229 are higher than the bottom surface of the fixing opening 301, and the opposite ends of the two lower surfaces 230 are lower than the bottom surface of the fixing opening 301. Thus, the pressing part 229 can more easily press and fix the reagent strip tray 300.

[0068] As attached Figure 6 Appendix Figure 7 Appendix Figure 9 As shown, an elastic element 224 is provided between the two fixing claws 204 and the platform 211 to keep the two fixing claws 204 in a fixed position. Each fixing claw is provided with a release passive element 231 for being detachably connected to the release device below the platform 211.

[0069] Specifically, an elastic element mounting part 232 is provided on the side of the first part 225 facing the first compartment door 101. The elastic element mounting part 232 is provided with a mounting groove for mounting the elastic element 224. The elastic element 224 can be, for example, a spring, an elastic buffer, or other feasible device, which is not limited here. A portion of the elastic element 224 extends into the mounting groove, and its outer end outside the mounting groove abuts against the lower protrusion 233 at the bottom of the platform 211. Taking the spring as an example, the elastic element 224 is normally in a compressed state. The reaction force of the two springs will exert a force on the two fixing claws 204 to drive them to move towards each other, thereby keeping the two fixing claws 204 in a fixed position. At this time, if a reagent strip tray 300 is positioned on the platform 211, the two fixing claws 204 press against the long side of the reagent strip tray 300 and fix the reagent strip tray.

[0070] When it is necessary to release the two retaining claws 204 from the reagent strip tray 300, the two retaining claws 204 are moved in opposite directions to separate from the reagent strip tray 300. At this time, the two retaining claws 204 switch to the released position. Specifically, this is achieved through the release device 205.

[0071] Correspondingly, the release passive member 231 is provided on the side of the first part 225. The release passive member 231 is located on the side of the first part 225 facing away from the first compartment door 101. The release passive member 231 can be a rolling element whose axis extends along the first horizontal direction X. The rolling element can be a bearing, roller, etc., which are not limited here.

[0072] As attached Figure 6 Appendix Figure 9As shown, the release device 205 includes a release block 234 located above the carrier plate 201 and below the platform. The release block 234 is provided with a release driving surface 235 corresponding to each of the release passive components 231. The release driving surface 235 is an inclined surface, an arc surface, etc., preferably an inclined surface parallel to the first horizontal direction X, and the two release driving surfaces 235 are distributed in a figure-eight shape. The release block 234 is connected to a release drive mechanism 236 that drives it to move up and down. The release drive mechanism 236 can be various feasible devices, such as an electric cylinder, a pneumatic cylinder, a hydraulic cylinder, etc. In this embodiment, the release drive mechanism 236 includes a third motor 237 disposed at the bottom of the carrier plate 201. The third motor 237 is a known lead screw motor. The movable nut 238 of the lead screw motor is connected to the release block 234, so that the lead screw motor drives the movable nut to move up and down along the screw, thereby driving the release block 234 to move up and down. At the same time, the bottom of the release block 234 is provided with a guide rod 239 extending in the vertical direction. The guide rod 239 is movably disposed in a guide sleeve disposed on the carrier plate 201. When the fixed claw 204 is in the fixed position, the gap between the two release driving surfaces 235 is located below the two release passive members 231. When it is necessary to switch the fixed claw 204 to the fixed release position, the release block 234 is driven to rise by the third motor 237. After the two release driving surfaces 235 contact each of the release passive members 231, as the release driving surfaces 235 continue to rise, they push the two release passive members 231 to move back to back, thereby causing the two fixed claws 204 to move back to back to open and switch to the fixed release position.

[0073] Of course, in other embodiments, the release driving surface 235 may also be provided on the fixing claw 204, and the release passive member 231 may be provided on the release block 234.

[0074] Simultaneously, a proximity sensor or similar device can be installed on the platform 211 to detect whether a reagent strip tray 300 is placed on the platform 211. When a reagent strip tray 300 is detected or an instruction to close the first compartment door 101 is received, the control device controls the release mechanism to drive the release block 234 downward, causing the two fixing claws 204 to reset to their fixed positions and fix the reagent strip tray 300 on the platform 211. When the control device receives an instruction to open the first compartment door 101, it can control the release mechanism to release the first fixing device 203 from fixing the reagent strip tray 300 after the first compartment door 101 is opened.

[0075] As attached Figure 1 Appendix Figure 2As shown, a material storage component 400 is provided inside the outer shell 100, located next to the reagent strip storage reactor 200. The material storage component 400 and the reagent strip storage reactor 200 are located on the same side of the outer shell 100. A second door opening corresponding to the material storage component 400 is provided on the outer shell 100, and a second compartment door 102 for opening and closing the second door opening is provided on the outer shell 100.

[0076] As attached Figure 10 , 12 As shown, the material storage assembly 400 includes a storage body 401. The top of the storage body 401 is provided with a first storage position 402, a second storage position 403, and a third storage position 404. The first storage position 402 is used to store centrifuge tubes 405, test tubes, etc.; the second storage position 403 is used to store pipette tips 406; and the third storage position 404 is used to store medicine bottles 407. The first and second storage positions 402 and 403 are insertion / receiving pipes, distributed around the outer periphery of the third storage position 404. The third storage position 404 is a storage slot located at the top center of the storage body 401. The top opening of the medicine bottle at the third storage position 404 can be covered by a detachable cap 408. Furthermore, a top cover (not shown in the figure) can be detachably connected to the top of the storage body 401 via a snap-fit ​​connection. The top cover effectively covers the top of the storage body 401, thereby preventing consumables from being contaminated by the external environment.

[0077] As attached Figure 11As shown, since the nozzle 406 needs to be replaced frequently, a certain recycling container is required to store the discarded nozzle 406. In order to avoid the recycling container occupying extra space, the recycling container is set in the material storage component. Specifically, the storage body 401 includes a storage slot 410 and a material storage device 411 disposed above the storage slot 410. The material storage device 411 and the storage slot 410 are detachably connected, for example, they are connected by a snap-fit, or the two are connected by a rotating snap-fit ​​structure. Specifically, the material storage 411 includes a base plate 412 and a storage body 413 disposed on the base plate 412. The base plate 412 has a plurality of snap-fit ​​holes 414 evenly distributed around its edge. The snap-fit ​​holes 414 are L-shaped. At the same time, a snap-fit ​​block 415 corresponding to each snap-fit ​​hole 414 is disposed on the top of the storage groove 410. The snap-fit ​​block 415 is L-shaped or C-shaped. When snapping, the wider part of the snap-fit ​​hole 414 is aligned with the snap-fit ​​block 415 and the snap-fit ​​block passes through the wider part. Then, the storage body 413 is rotated so that the snap-fit ​​block 415 rotates to the narrower part of the snap-fit ​​hole 414, thereby realizing the connection between the two. At this time, the axis of the base plate 412 extends in the vertical direction. Furthermore, a through hole 416 communicating with the storage slot is provided on the base plate 412, and an insertion hole 417 matching the through hole 416 is provided on the memory body 413. The through hole 416 and the insertion hole 417 are combined to form a waste recycling channel, and the storage slot 410 is the recycling container.

[0078] As attached Figure 2 As shown, the material storage component 400 is detachably mounted on a rotating mechanism 500 that drives its rotation, the rotating mechanism being mounted on a base.

[0079] As attached Figure 10As shown, the rotating mechanism includes a turntable 502, which is used to support and position the material storage assembly 400 and to install a second fixing device. The turntable 502 is connected to a rotating power mechanism that drives its rotation. The rotating power mechanism is, for example, a servo turntable. Of course, in other embodiments, the side of the turntable 502 is a circumferential surface and it is rotatably mounted on a support platform 503 via bearings. The rotating power mechanism includes a friction wheel 504 that fits against the side of the turntable 502. The friction wheel 504 is connected to a friction drive motor 505 that drives its rotation. The friction drive motor 505 is fixed on the support platform 503 and its position can be adjusted radially along the turntable. Meanwhile, a locking mechanism 506 is also provided on the support platform 503. The locking mechanism 506 includes a locking pin 507, which is connected to a locking drive mechanism 508 that drives it to translate radially along the turntable 502. The locking drive mechanism 508 is, for example, a cylinder or an electric cylinder. Preferably, the locking drive mechanism 508 includes a second eccentric shaft 509. The main shaft portion of the second eccentric shaft 509 is concentrically connected to a locking drive motor 510 that drives its rotation. The eccentric portion of the second eccentric shaft 509 is concentrically connected to a roller 511. The roller 511 abuts against the end of the locking pin 507 facing away from the turntable 502. Meanwhile, the locking pin 507 is reciprocally mounted on a mounting base 529. The locking pin 507 is also connected to an energy storage element (not shown in the figure) that keeps it abutting against the roller 511. The energy storage element is preferably a spring fitted on the locking pin 507 and located inside the mounting base 529. Of course, the energy storage element can also be located outside the mounting base, or it can be other parts that can produce elastic deformation, such as a spring sheet, etc., which are not limited here. Furthermore, the side of the turntable 502 is provided with a plurality of locking holes 530 that are adapted to the locking pin 507. The position of the locking holes can be determined according to the position to which the turntable 502 needs to rotate, and is not limited here. When the turntable 502 rotates to a stop position, one of the locking holes is directly opposite the locking pin 507. At this time, the locking drive motor 510 drives the roller 511 to rotate, thereby causing the locking pin 507 to extend into the locking hole to lock the turntable 502. When unlocking, the locking drive motor 510 continues to rotate or rotates in the opposite direction, thereby causing the locking pin 507 to retract from the locking hole, and the turntable 502 can continue to rotate.

[0080] As attached Figure 12 As shown, the rotating mechanism 500 is provided with a second fixing device 501 for fixing the material storage component on the rotating mechanism 500.

[0081] As attached Figure 11 Appendix Figure 12As shown, to facilitate the installation of the second fixing device 501, the side of the material storage component 400 includes a first side that is generally flat and a second side that is generally semi-circular. Correspondingly, the second fixing device 501 includes a sample tube holder 512 fixed on the turntable. The side of the sample tube holder 512 includes a first mating surface adapted to the first side and a second mating surface adapted to the second side. Thus, the material storage component 400 and the sample tube holder 512 form a shape similar to an oak barrel. Of course, the shape of the material storage component 400 and the sample tube holder 512 can also be set to other shapes as needed.

[0082] To effectively secure the material storage assembly 400 to the rotating mechanism 500, as shown in the attached figure... Figure 12 As shown, a clamping device 513 is provided on the sample tube holder 512. The clamping device 513 includes two clamping rods 514, which are approximately J-shaped, and their lower ends are connected to the two ends of a rotating shaft 515. The rotating shaft 515 extends horizontally and is rotatably mounted on the sample tube holder 512. A first gear 516 is coaxially mounted on the rotating shaft 515. The first gear 516 meshes with a first rack 517, which extends vertically and is fixed on a vertically movable frame 518. The vertically movable frame 518 is movably mounted on a fourth guide rail 519 and is connected to a clamping power source 520 that drives its vertical movement. The clamping power source 520 is fixed on the turntable 502 and can be an electric cylinder, hydraulic cylinder, pneumatic cylinder, or lead screw motor, etc., without limitation here. The fourth guide rail 519 is located on the side of the clamping power source 520.

[0083] As attached Figure 12 Appendix Figure 13 As shown, the bent portions 521 at the upper ends of the two clamping rods 514 extend towards the material storage assembly 400. Thus, when the clamping power source 520 drives the rotating shaft 515 to rotate, the clamping rods 514 rotate downwards, causing their bent portions 521 to press against the top of the material storage assembly 400 for fixation. Simultaneously, a positioning boss can be provided below the bent portions 521. A pressure block 418 is provided on the top of the material storage assembly 400, and the pressure block 418 has a positioning groove 419 corresponding to the positioning boss. During clamping, the positioning boss is embedded in the positioning groove 419, thus better limiting the horizontal movement of the material storage assembly 400.

[0084] When it is necessary to replace the material storage component 400 or the material storage device 411, after opening the second compartment door, the clamping rod 514 can be driven to rotate upward to separate from the material storage component 400. The clamping rod 514 is rotated to a position that does not affect the replacement operation and then stopped. At this time, the material storage component can be completely replaced, or only the material storage device can be replaced.

[0085] As attached Figure 12 As shown, the sample tube holder 512 has at least one sample tube storage position. Each sample tube storage position includes a countersunk hole 522 extending downwards from the top of the sample tube holder 512 and an insertion slot 523, spaced apart and coaxially disposed below the countersunk hole 522, with a gap maintained between the insertion slots. A vial 524 can be stored in the countersunk hole 522. Simultaneously, a sample tube 525 can be inserted into the insertion slot 523 through the countersunk hole 522. At this time, the cap 527 of the sample tube 525 is located above the sample tube holder 512. Furthermore, a clearance opening 526 corresponding to each countersunk hole 522 is formed at the second mating surface of the sample tube holder 512 to facilitate barcode reading on the side wall of the sample tube 525; however, this is not mandatory.

[0086] As attached Figure 2 Appendix Figure 12 As shown, the reason for maintaining a gap between the countersunk hole 522 and the insertion slot 523 is to cooperate with the cap removal mechanism 600 to remove the cap 527 of the sample tube 525. Specifically, the cap removal mechanism 600 is provided inside the housing 100, located next to the material storage assembly 400, and the cap removal mechanism 600 is located inside the rotating mechanism 500.

[0087] As attached Figure 14 As shown, the cap-removing mechanism 600 removes the cap by having a cap-removing needle 601 pass horizontally through the cap 527 on the sample tube 525 and move upward.

[0088] In detail, see attached Figure 15 As shown, the cap-removing mechanism 600 includes a vertical plate 602, on which a first gripper 603 is movably mounted vertically. The first gripper 603 is connected to a lifting drive mechanism 604 that drives its vertical movement. The first gripper 603 includes a C-shaped fixing frame 605, which is movably mounted on the vertical plate and connected to the lifting drive mechanism. The specific structure of the lifting drive mechanism 604 can be customized as needed, for example, by using a lead screw motor or other devices capable of linear movement; this is not limited here.

[0089] As attached Figure 15As shown, a first claw body 606 is horizontally movably disposed at the bottom of the upper plate of the fixing frame 605. The first claw body 606 includes a vertical clamping part 607. The first claw body 606 is connected to a first driver 608 that drives its horizontal movement. A second claw body 609 is horizontally movably disposed at the top of the lower plate of the fixing frame 605. The second claw body 609 is connected to a second driver 610 that drives its horizontal movement. The second claw body 609 includes a cap-pulling pin 601 with its tip facing the vertical clamping part 607 and corresponding to the position of the vertical clamping part 607. The axial direction of the cap-pulling pin is consistent with the movement direction of the first and second claw bodies. The first driver 608 and the second driver 610 can both be cylinders, electric cylinders, or lead screw motors, etc., and are not limited here.

[0090] When it is necessary to remove the cap, the first driver 608 and the second driver 610 maintain a distance between the vertical clamping part 607 and the cap-removing needle 601 that is not less than the outer diameter of the cap 527. When the cap 527 is directly below the gap between the vertical clamping part 607 and the cap-removing needle 601, the lifting drive mechanism 604 drives the first gripper 603 to move down until the vertical clamping part 607 and the cap-removing needle 601 are on both sides of the cap 527. At this time, the first driver 608 and the second driver 610 drive the vertical clamping part 607 and the cap-removing needle 601 to move towards each other, so that the cap-removing needle 601 penetrates the cap 527 and cooperates with the vertical clamping part 607 to clamp the cap 527. Then, the lifting drive mechanism 604 drives the first gripper 603 to move up, separating the cap 527 from the tube body 528, and finally removing the cap.

[0091] Since the tube body 528 is not fixed when the first gripper 603 moves upward, in order to prevent the tube body 528 from moving with the tube cap 527, as shown in the attached... Figure 15 As shown, the cap removal mechanism 600 further includes a second gripper 612, which is used to fix the tube body 528 of the sample tube 525 in the sample tube holder 512 when the cap removal needle 601 moves upward to remove the cap, and to cooperate with the cap removal needle 601 to separate the cap 527 from the tube body 528 after the cap 527 is separated from the tube body 528.

[0092] Specifically, the second gripper 612 is mounted on a transfer frame 613 on the side of the upright plate. The transfer frame and the fixed frame 605 are located on the same side of the upright plate. A turbine 614 is rotatably mounted on the transfer frame 613. The axis of the turbine 614 is horizontal and perpendicular to the moving direction of the first gripper body 606 and the second gripper body 609. The turbine 614 meshes with a worm gear 615. The worm gear 615 extends vertically and is connected to a power source 616 that drives its rotation. The power source is a motor and is fixed on the transfer frame 613. The power source 616 drives the worm gear 615 to rotate, thereby driving the turbine 614 to rotate.

[0093] A synchronizing arm 617 is connected to the side of the turbine 614. The synchronizing arm 617 is connected to the top of a second gripper 612 and near the tail end of the second gripper 612. The second gripper 612 can be a known electric gripper or pneumatic gripper. The opening and closing directions of the two gripping claws 618 of the second gripper 612 are parallel to the axial direction of the turbine 614. When the turbine 614 rotates, the second gripper 612 can rotate between a horizontal state and a vertical state or an inclined state. In the horizontal state, the length direction of the second gripper 612 is parallel to the moving direction of the first claw 606 and the second claw 609 and extends approximately along the first horizontal direction. In the vertical or inclined state, the gripping claws of the second gripper face downwards. Meanwhile, when the second gripper 612 is in a horizontal state, the two gripping claws of the second gripper 612 can extend into the gap between the countersunk hole 522 and the insertion groove 523 and clamp and fix the tube body 528 of the sample tube 525, thereby preventing the tube body 528 from moving upward with the tube cap 527 when the first gripper 603 moves upward.

[0094] Of course, in other embodiments, the second gripper is not necessary. For example, a clamping mechanism can be provided on the sample tube holder to fix the sample tube body. The corresponding clamping mechanism is a known technology. For example, a cylinder can be used to drive a pressure head to press against the side wall of the tube body. This is not limited here.

[0095] After the first and second grippers work together to remove the cap from the sample tube, the first gripper retracts away from the sample tube, while the second gripper rotates in the opposite direction to either an inclined or vertical position.

[0096] When it is necessary to remove the cap 527 from the first gripper 603, as shown in the attached... Figure 14As shown, when the second gripper 612 is in a horizontal state, the two gripping claws of the second gripper 612 can be opened first, and then the first gripper 603 can be lowered to move the cap 527 it is holding between the two gripping claws of the second gripper 612. Next, the second gripper 612 drives the two gripping claws to close and hold the lower part of the cap 527. Subsequently, the second actuator 610 drives the second claw 609 to move away from the first claw 606, thereby pulling the cap removal needle 601 out of the cap. At this time, the cap is held by the second gripper 612. Then, the second gripper 612 can rotate downward to its lowest state and discard the cap it holds into the waste box (not shown in the figure). Of course, the second gripper can also drop the cap into the storage slot through the cap dropping port described below. In this case, the upright plate needs to be set on a translational avoidance mechanism. The translational avoidance mechanism is, for example, a servo linear module. Of course, it can also be other mechanisms that can realize linear movement, which are not limited here. The translational avoidance mechanism drives the upright plate to move along the axial direction of the cap removal needle. When it is necessary to detach the cap from the cap removal needle, the translational avoidance mechanism drives the upright plate to move away from the rotating mechanism, so that the first gripper and the second gripper will not interfere with the rotation of the material storage component and the sample tube holder on the rotating mechanism.

[0097] Of course, in other embodiments, as shown in the appendix Figure 16 As shown, a cap-feeding opening 420 can be provided at an appropriate height on the side of the storage slot. The cap-feeding opening 420 is close to the sample tube holder, and there can be one or more cap-feeding openings. Preferably, there are two cap-feeding openings 420, which are respectively on both sides of the sample tube holder.

[0098] When a cap is discarded, after the first gripper pulls out the cap and retracts, the rotating mechanism drives the receiving slot 410 to rotate, causing the cap-dispensing opening 420 to rotate towards the first gripper. Then, the first gripper can move downwards so that the cap it grips is directly opposite the cap-dispensing opening 420. Next, the first gripper drives the cap to move into the cap-dispensing opening 420. Subsequently, the first gripper moves downwards a certain distance so that a portion of the cap is below the cap-dispensing opening 420. At this time, the second gripper moves away from the cap-dispensing opening 420. Because the cap is blocked by the inner wall of the receiving slot, it is pulled out of the cap when the cap-pulling needle retracts, and the cap falls into the receiving slot. This avoids the need for an additional waste box and a translational avoidance mechanism, simplifying the overall structure and increasing efficiency by eliminating the need for a second gripper. After a cap is discarded, the first gripper moves back to its original position, waiting for the next cap-pulling operation.

[0099] As attached Figure 2As shown, a centrifugation mechanism 700 is also provided inside the outer casing 100. The centrifugation mechanism 700 is located on the side of the cap removal mechanism 600 near the reagent strip storage reactor 200 and adjacent to the material storage assembly.

[0100] As attached Figure 17 Appendix Figure 18 As shown, the centrifuge mechanism 700 includes a centrifuge worktable 701 mounted on a base. The worktable is approximately C-shaped with a notch to avoid the cap-removing mechanism. A centrifuge shaft 702 is rotatably mounted on the worktable 701. The centrifuge shaft 702 extends vertically, and its lower end is connected to a centrifuge drive motor 704 via a transmission mechanism 703. The transmission mechanism 703 can be, for example, a known synchronous belt drive mechanism, gear drive mechanism, or a structure consisting of a sprocket and chain, and is not limited here. The upper end of the centrifuge shaft 702 is coaxially connected to a centrifuge disc 705. The centrifuge disc 705 has multiple centrifuge tube storage sleeves 706 evenly spaced around its circumference for inserting centrifuge tubes 405. The centrifuge tube storage sleeves 706 normally extend vertically and can be hinged to the centrifuge disc, so that the centrifuge tube storage sleeves can be in an inclined state during centrifugation. Meanwhile, a protective cover 707 is also provided on the centrifuge workbench 701. An operating hole is provided on the top plate of the protective cover (not shown in the figure). Each centrifuge tube storage sleeve 706 can be rotated to a position directly opposite the operating hole so that the centrifuge tube 405 can be placed into the centrifuge tube storage sleeve 706. The cap removal mechanism is also provided on the centrifuge workbench.

[0101] As attached Figure 2 Appendix Figure 19 As shown, the outer casing 100 also contains a reagent strip processing mechanism 800, which is used to perform operations such as opening the cap and membrane of the reagent strip 303 and moving the probe 304. The reagent strip processing mechanism 800 includes a multi-directional moving mechanism 801, which is connected to the processing component 802 and drives it to move along a first horizontal direction and a vertical direction. The multi-directional moving mechanism 801 drives the processing component 802 to move to the reagent strip 303 on the shaker 202 to perform operations such as opening the membrane, opening the cap, and moving the probe 304.

[0102] As attached Figure 20As shown, the multi-directional movement mechanism 801 is located on the inner wall of the frame on the base within the housing 100 and above the reagent strip storage reactor 200. The multi-directional movement mechanism 801 includes a lateral movement mechanism, which can employ a known servo module or a structure consisting of a motor and a lead screw to drive a lateral movement frame 816 to reciprocate along a first horizontal direction. A height adjustment frame 817 is movably mounted on the lateral movement frame 816, and the height adjustment frame 817 is connected to a height adjustment drive mechanism (not shown in the figure) that drives its vertical movement. The processing component 802 is mounted on the height adjustment frame 817.

[0103] The specific structure of the processing component 802 can be referred to the structure described in the patent documents cited in the background art.

[0104] As attached Figure 20 As shown, in this embodiment, the processing component 802 includes a probe gripper 803, a cap opener 804, and a film opener 805 disposed on the height adjustment frame 817.

[0105] As attached Figure 21 Appendix Figure 22 As shown, the probe gripper 803 includes a gripper base 806, on which a gripping strip 807 is provided. The gripping strip 807 extends along the second horizontal direction Y, and a row of gripping grooves 808 arranged along the second horizontal direction Y are formed on the gripping strip 807. The gripping grooves 808 extend upward from the bottom surface of the gripping strip 807, and the opening of the gripping groove 808 is located on the side of the gripping strip 807 facing away from the first compartment door 101. The gripping grooves 808 are V-shaped grooves or wedge-shaped grooves, and their number and position correspond one-to-one with the number and position of the probes 304 of the reagent strip 303 on the reagent strip tray 300 on the shaker 202.

[0106] The gripper seat 806 is further provided with a gripping block 809. The gripping block 809 is movably disposed at the bottom of the gripper seat 806 along a first horizontal direction X, and is connected to a gripping driver 810 that drives its movement along the direction X. The gripping driver 810 may be an electric cylinder or other device connected to the gripping block 809. In this embodiment, the gripping driver 810 is a lead screw motor, and the nut of the lead screw motor is connected to the gripping block 809, so that when the nut moves along the screw of the lead screw motor, it drives the gripping block 809 to move. The gripping block 809 is provided with an elastic gripper 811 facing each of the gripping slots 808. The elastic gripper 811 may be a known ball plunger, or it may be a structure similar to a ball plunger, which is not limited here.

[0107] During clamping, the groove wall of the clamping groove 808 is first brought into contact with the needle body of the probe 304. Then, the clamping driver 810 drives the clamping block 809 to move towards the clamping bar. The ball head of the elastic clamp 811 presses the probe 304 into the clamping groove 808. Then, the probe jaws move upward to pick up and move the probe 304.

[0108] As attached Figure 20 Appendix Figure 22 As shown, the cap opener 804 is disposed on the side of the gripper seat 806 facing the first compartment door 101, and includes a plurality of downwardly extending cap opening strips 812. The plurality of cap opening strips 812 are evenly distributed along the second horizontal direction Y. Each cap opening strip 812 is adapted to the position of the probe protection cap 305 of a reagent strip 303 on the reagent strip tray 300. The lower end of the cap opening strip 812 forms an insertion cone, which can be inserted between the two elastic buckles 306 of the probe protection cap 305 and make them move along the second horizontal direction Y. The horizontal Y-axis opening enables the release of the buckle. At the same time, the bottom of the opening insert 812 is higher than the bottom of the clamping strip 807, and a predetermined gap is maintained between the opening insert 812 and the clamping strip 807. When the opening insert 812 is inserted between the two elastic buckles 306, the side of the clamping strip 807 facing the opening insert 812 abuts against the end of the elastic buckle 306. Thus, after the elastic buckle 306 is released, the movement of the clamping strip 807 can drive the probe protective cover 305 to flip upward and open.

[0109] As attached Figure 20 Appendix Figure 22 As shown, the membrane opener 805 includes a membrane opener plate 813. Below the membrane opener plate 813 is a row of membrane opener cones 814, each corresponding to a cap-opening insert 812, with their tips pointing downwards. The membrane opener plate 813 is connected to a membrane opener actuator 815 that drives its up-and-down movement. The membrane opener actuator 815 can be an electric cylinder, a lead screw motor, or other feasible device; no limitation is made here. It is mounted on the height adjustment frame 817 and connected to the membrane opener plate 813 via a sliding frame 818 that can move up and down relative to the height adjustment frame 817. When membrane opening is required, the membrane opener cones 814 are moved directly above the protective membrane to be opened. Then, the membrane opener actuator 815 drives the membrane opener plate 813 downwards, causing the tips of the membrane opener cones 814 to move below the probe grippers and puncture the protective membrane on the reagent strip 303.

[0110] As attached Figure 2 Appendix Figure 23As shown, the testing device further includes a sample consumable transfer mechanism 900. The sample consumable transfer mechanism 900 includes a base frame 901, on which a first translation mechanism 902 is disposed. A second translation mechanism 903 is disposed on the first translation mechanism 902, and a vertical movement mechanism 904 is disposed on the second translation mechanism 903. A pipette 905 is disposed on the vertical movement mechanism 904. The first translation mechanism 902 drives the second translation mechanism to move along a second horizontal direction Y, the second translation mechanism 903 drives the vertical movement mechanism 904 to move along a first horizontal direction X, and the vertical movement mechanism 904 drives the pipette 905 to move vertically. The first translation mechanism 902, the second translation mechanism 903, and the up-down movement mechanism 904 can drive the pipette 905 to move to the material storage component 400 to obtain consumables, and can also move consumables, medicines, samples, etc. to the centrifugation mechanism 700 and the reagent strip 303. The specific movement range of the pipette 905 driven by them can be designed as needed and is not limited here.

[0111] The first translation mechanism 902 includes a first slide 907 movably mounted on a first slide rail 906 on the base frame 901. The first slide 907 is also connected to a first translation drive mechanism 908 that drives it to move along the first slide rail 906. The first translation drive mechanism 908 is implemented by a first motor 909 and a synchronous belt mechanism. The first motor 909 is located at one end of the base frame 901 and is connected to one pulley of the synchronous belt mechanism. The other pulley of the synchronous belt mechanism is rotatably mounted at the other end of the base frame 901. A synchronous belt is fitted between the two pulleys and is connected to the first slide 907.

[0112] As attached Figure 23 As shown, since the first slide 907 is cantilevered on the base frame 901, in order to ensure the stable movement of the first slide 907, a limiting wheel 910 is provided at the end of the first slide 907 connected to the base frame 901. The axis of the limiting wheel 910 extends along the first horizontal direction X. At the same time, the limiting wheel 910 is rolled in the strip hole 911 on the base frame 901. The strip hole extends along the second horizontal direction. Thus, the limiting wheel 910 can minimize the impact of the outer end of the first slide 907 on the sliding on the first slide rail 906 due to the drooping of the load and gravity.

[0113] The specific structures of the second translation mechanism 903 and the vertical movement mechanism 904 can be referred to the first translation mechanism 902, and will not be described in detail here. Of course, in other embodiments, the first translation mechanism 902, the second translation mechanism 903, and the vertical movement mechanism 904 can also be implemented using other structures, for example, they can be assembled using known servo linear modules.

[0114] As attached Figure 24 Appendix Figure 25 As shown, the pipette 905 includes a suction tube 912, the lower end of which can be inserted into a pipette tip or centrifuge tube to grasp them. The suction tube 912 is movably mounted on a sleeve 913 in a vertical direction. The sleeve 913 is fixed to a lifting frame 918 of a vertical moving mechanism 904. The lifting frame 918 is C-shaped, and the sleeve 913 is fixed below the lower plate of the lifting frame 918. The lifting frame is also equipped with a suction assembly 914, which includes a sealing connection to the... On the upper end of the suction tube 912, a sealing sleeve 915 is provided, and a piston rod 916 is sealed inside the sealing sleeve 915. The upper end of the piston rod 916 extends above the sealing sleeve 915 and is connected to the upper connecting plate 919 of the lifting frame 918. The sealing sleeve 915 is movably mounted on the lifting frame 918 via a known guide rail assembly 920, and is connected to a suction actuator 917 that drives its up-and-down movement. The suction actuator 917 may be, for example, an electric cylinder fixed on the lifting frame 918. More preferably, to make the structure more compact, the suction driver 917 is a lead screw motor. The motor body of the lead screw motor is connected to the sealing sleeve, and the nut of the lead screw motor is fixedly connected to the upper connecting plate 919 of the lifting frame 918. Thus, when the lead screw motor drives its screw to rotate, the screw moves up and down relative to the fixed nut, causing the motor body to move up and down, which in turn drives the sealing sleeve 915 to move up and down for suction. Thus, the sealing sleeve 915 drives the suction tube 912 to move up and down. When the suction tube 912 moves above the sleeve 913, the centrifuge tube 405, test tube, etc. inserted at the lower end of the suction tube 912 can be blocked by the bottom surface of the sleeve 913 and thus separated from the suction tube 912.

[0115] As attached Figure 3 As shown, a reading component A is also provided inside the housing 100. The reading component A is located inside the shaker 202 within the housing, and below the reading hole where the reagent strips 303 on the shaker 202 extend out of the stage 211. The reading component A generates fluorescence by laser excitation on the surface of the probe 304, and receives the light signal through a receiver to obtain and output the detection result. Its specific structure and detection principle are known technologies and are not innovative in this invention, so they will not be described in detail here. The reading component A is mounted on a position switching mechanism B, which drives the reading component A to move along the second horizontal direction Y, thereby realizing the reading of multiple reagent strips 303 on the reagent strip tray 300. The position switching mechanism B can use a structure composed of a motor and a lead screw to drive the platform to move, or it can use a known servo module to drive the platform to move, which is not limited here. The reading component A is mounted on the platform.

[0116] As attached Figure 2 Appendix Figure 3 As shown, the housing 100 also contains multiple information readers C, such as barcode scanners or electronic tag readers. One information reader C is used to read the barcode or electronic tag information on the side wall of the sample tube 525, and another information reader C is used to read the barcode or electronic tag information on the reagent strip 303. Furthermore, to facilitate reliable information reading, each information reader can be mounted on a direction switching mechanism D that drives it to change its reading direction. For example, a geared motor can be used to drive a rotating base to rotate as the direction switching mechanism D; this is not limited here. Simultaneously, proximity switches or other sensors can be installed at appropriate locations to determine whether each mechanism has moved into position and to detect whether there is a reagent strip tray 300 on the shaker 202. These are known technologies and will not be elaborated upon here.

[0117] As attached Figure 1 As shown, a human-machine interface screen E is also provided outside the outer shell 100. The human-machine interface screen E is located on the side where the first compartment door 101 is located. The operator can control the detection equipment through the human-machine interface screen E, such as controlling the detection equipment to open the first compartment door 101 and start the detection, etc. The human-machine interface screen E can also display the detection results, etc.

[0118] The following section focuses on the detection method of the aforementioned detection equipment, and the steps are as follows:

[0119] Before testing, the operator can open the second compartment door 102, place the reagent bottle to be used in the third storage position of the material storage component 400, place the centrifuge tube 405 in the first storage position 402, and place the pipette tip 406 in the second storage position. Then, the operator can control the second fixing device to fix the material storage component 400 through the human-machine interface screen E or control buttons. Of course, in other embodiments, the reagent bottle, centrifuge tube 405, and pipette tip 406 can also be externally mounted onto the material storage component 400, and then the entire material storage component 400 can be installed onto the receiving slot 410. Finally, the operator can control the second fixing device to fix the material storage component 400. At the same time, after the second fixing device fixes the material storage component 400, the operator can control the rotating mechanism 500 to rotate the second fixing device to face the second compartment door 102 for placing the sample tube 525.

[0120] Simultaneously, the operator can send a command to the control device of the testing equipment to open the first compartment door 101 through the human-machine interface screen E. The control device controls the first drive mechanism 207 to drive the carrier plate 201 to move outward and move the shaker 202 to the outside of the housing 100. The fixing claws 204 of the first fixing mechanism are opened by the release device 205. The test strip tray 300 loaded with test strips 303 is placed on the platform 211 of the shaker manually. Then, the operator sends an instruction to the control device to close the first compartment door 101 through the human-machine interface screen E. Before or simultaneously with the control device controlling the first drive mechanism 207 to drive the carrier plate 201 to move into the housing 100, the control device controls the release device 205 to separate from the first fixing device 203 so that the two fixing claws 204 close and fix the test strip tray 300 on the shaker 202.

[0121] When testing is required, the second compartment door 102 can be opened to insert the sample tube 525 into the sample tube holder 512. After closing the second compartment door 102, a start testing command can be sent through the human-machine interface screen E, or a start testing signal can be generated through the start button.

[0122] Subsequently, the control device rotates the sample tube 525 to the cap removal position according to a preset program. At this time, the information of the sample tube 525 is read first to determine the items to be tested. Simultaneously or subsequently, the control device controls the cap removal mechanism 600 to remove the cap 527 from the sample tube 525 and reset it after cap removal.

[0123] While removing the cap, the control device reads the information of the reagent strip 303 through the information reader C. When it is determined that the reagent strip 303 matches the test item, the control device controls the reagent strip processing mechanism to open the cap and open the film of the reagent strip 303.

[0124] Simultaneously or after removing the cap, the control device controls the sample consumable transfer mechanism 900 to pick up the centrifuge tube 405 and place it on the centrifugation mechanism 700. Then, the control device controls the sample consumable transfer mechanism 900 to pick up the pipette tip 406 and add the sample from the sample tube with the cap 527 removed to the centrifuge tube 405 at the centrifugation mechanism. Subsequently, the control device controls the centrifugation mechanism to perform centrifugation and controls the sample consumable transfer mechanism 900 to discard the used pipette tip 406 and replace it with another pipette tip 406. After the centrifugation mechanism 700 completes centrifugation, the control device controls the sample consumable transfer mechanism 900 to aspirate the centrifuged sample and add it to the sample well of the reagent strip 303. Then, the control device controls the sample consumable transfer mechanism 900 to replace the pipette tip 406 and add the reagent from the reagent bottle 407 to the reagent strip 303 to complete the liquid addition.

[0125] Upon entering the reaction process, the control device controls the reagent strip processing mechanism to grasp the probes 304 on the reagent strip 303 and, according to the determined reaction process, cause the probes 304 to sequentially enter different holes on the reagent strip 303. When the probes are inserted into the holes, the control device controls the shaker 202 to start and shake the reagent strip 303, finally causing the reacted probes to remain in the reading holes.

[0126] Finally, the control device controls the position switching mechanism B to drive the reading component A to move below the reading hole of the corresponding reagent strip 303 to take a reading, and displays the reading result on the human-machine interaction screen E.

[0127] This invention has many other embodiments, and all technical solutions formed by equivalent transformations or equivalent transformations fall within the protection scope of this invention.

Claims

1. A testing device, comprising a housing, wherein a reagent strip storage reactor is disposed within the housing, characterized in that: The reagent strip storage reactor includes a carrier plate, on which a shaker is mounted. The shaker has a first fixing device for securing a reagent strip tray on the shaker using fixing claws. The carrier plate also has a releasing device for releasing the first fixing device from securing the reagent strip tray on the shaker. The releasing device is detachably connected to the first fixing device. When the releasing device is separated from the first fixing device, the first fixing device secures the reagent strip tray on the shaker. The first fixing device includes a set of fixing claws that move and open / close at least along a second horizontal direction, perpendicular to the first horizontal direction. The first horizontal direction is defined as the length direction of the platform of the shaking table. An elastic element is provided between each fixed claw and the platform of the shaking table to keep the fixed claw in a fixed position. Each fixed claw is provided with a release passive element for detachable connection with the release device below the platform. The release device includes a release block, and the release block is provided with a release driving surface corresponding to each release passive element. The release block is connected to a release driving mechanism that drives it to move up and down. During the upward movement of the release block, the release driving surface drives the release passive element to move away from the platform so that the multiple fixed claws open. The platform is connected to a second drive mechanism that drives its swaying. The second drive mechanism includes a second motor disposed at the bottom of the platform. The power output shaft of the second motor passes through a through hole in the platform and is connected to a first eccentric shaft. The first eccentric shaft includes a first shaft segment coaxial with the power output shaft and a second shaft segment eccentrically distributed with respect to the first shaft segment. A roller is coaxially connected to the second shaft segment above the first shaft segment and on the second shaft segment. The roller is disposed in an embedded hole at the bottom of the platform.

2. The detection device according to claim 1, characterized in that: The carrier plate is provided with rotatable limiting gears on both sides, and the housing is provided with limiting racks that can be separably meshed with each of the limiting gears. The limiting racks extend along a first horizontal direction. When the shaking table is located inside the housing, the limiting gear on each side meshes with the limiting rack on its corresponding side.

3. The detection device according to claim 1, characterized in that: The shaking bed is located on top of the carrier plate and at the outer end of the carrier plate. The shaking bed can be moved from inside the housing to outside the housing. The outer end of the carrier plate is provided with a first compartment door, and the inner side of the first compartment door is hinged to the carrier plate.

4. The detection device according to any one of claims 1-3, characterized in that: The outer shell contains a material storage component located next to the reagent strip storage reactor. The outer shell has a second compartment door corresponding to the material storage component. The material storage component is mounted on a rotating mechanism that drives its rotation. The rotating mechanism has a second fixing device that fixes the material storage component on the rotating mechanism.

5. The detection device according to claim 4, characterized in that: The material storage assembly includes a storage tank and a material storage device detachably disposed above the storage tank, wherein the material storage device is provided with a waste recycling channel communicating with the storage tank.

6. The detection device according to claim 4, characterized in that: The material storage assembly has a centrifuge tube storage position on its top, and a centrifuge mechanism is also provided inside the outer shell.

7. A reagent strip storage reactor, comprising a carrier plate, characterized in that: A shaker is provided on the carrier plate, and a first fixing device is provided on the shaker for fixing the reagent strip tray on the shaker by fixing claws. The carrier plate is also provided with a release device for driving the first fixing device to release the fixing of the reagent strip tray on the shaker. The release device is detachably connected to the first fixing device. When the release device is separated from the first fixing device, the first fixing device fixes the reagent strip tray on the shaker. The first fixing device includes a set of fixing claws that move and open / close at least along a second horizontal direction, which is perpendicular to a first horizontal direction. The first horizontal direction is defined as the length direction of the platform of the shaking table. An elastic element is provided between each fixing claw and the platform of the shaking table to keep the fixing claw in a fixed position. Each fixing claw is provided with a release passive element for detachable connection to the release device below the platform. The release device includes a release block, which is provided with a release driving surface corresponding to each release passive element. The release block is connected to a release driving mechanism that drives it to move up and down. During the upward movement of the release block, the release driving surface drives the release passive element to move away from the platform to open the plurality of fixing claws. The platform is connected to a second drive mechanism that drives its swaying. The second drive mechanism includes a second motor disposed at the bottom of the platform. The power output shaft of the second motor passes through a through hole in the platform and is connected to a first eccentric shaft. The first eccentric shaft includes a first shaft segment coaxial with the power output shaft and a second shaft segment eccentrically distributed with respect to the first shaft segment. A roller is coaxially connected to the second shaft segment above the first shaft segment and on the second shaft segment. The roller is disposed in an embedded hole at the bottom of the platform.

8. The detection method of the detection equipment according to any one of claims 1-6, characterized in that, Includes the following steps: Move the shaker outside the casing; The fixing claw of the first fixing device is opened by the release device; Place the reagent strip tray containing the reagent strips on the shaker, and separate the release device from the first fixing device so that the fixing claw closes to fix the reagent strip tray on the shaker. Move the shaker into the housing.

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