Chicken embryo allantoic fluid collecting device

Abstract

The utility model belongs to the technical field of biological pharmacy, and particularly relates to a chick embryo allantoic fluid collecting device which comprises a syringe needle, a needle stem and a pintle. The anti-blocking filtering piece comprises a sleeve, a housing and a connecting piece, the front end of the needle stem is covered with the housing, the risk that yolk is damaged in the collecting process can be reduced by means of the characteristics that the outer surface of the housing is smooth and free of edges and corners, and the egg yolk collecting device is convenient, rapid and high in yield and provides convenient conditions for follow-up production; a plurality of liquid inlet holes are formed outside the housing, so that liquid inlet paths can be dispersed, and the blocking risk caused by a single channel is reduced; the needle stem is sleeved with the sleeve, stable support is provided for the housing, and the stability of the collecting process is guaranteed; and finally, the connecting piece is arranged to be detachably connected with the pintle, so that assembling and disassembling can be facilitated, and cleaning and replacement are facilitated.

Description

Technical Field

[0001] This utility model belongs to the field of biopharmaceutical technology, specifically relating to a chicken embryo allantoic fluid collection device. Background Technology

[0002] Chicken embryo allantoic fluid is an important biological resource in fields such as avian embryonic development research, vaccine production, and biological product extraction. Chicken embryo allantoic fluid refers to the fluid present in the allantoic cavity of chicken embryos. It plays a crucial role in embryonic development, serving as an important site for gas exchange and nutrient absorption, a storage place for metabolic waste, and providing a stable developmental environment for the embryo.

[0003] The extraction of chicken embryo allantoic fluid is of great significance. In scientific research, it helps to deepen the understanding of mechanisms such as gas exchange and nutrient metabolism during embryonic development, providing materials and data for research in avian embryology and other fields. In vaccine production, many viruses can proliferate within the allantoic cavity of chicken embryos, and the extracted allantoic fluid, after processing, can be used to make vaccines. Furthermore, the bioactive substances contained within it have wide applications in biopharmaceuticals and other fields. In addition, chicken embryo allantoic fluid is also used for biosafety assessment in drug and cosmetic development.

[0004] Currently, the main method involves using a vacuum pump connected to a syringe needle to extract allantoic fluid from the allantoic cavity of the chicken embryo. However, this method has significant drawbacks. Specifically, during the extraction process, the shell membrane is easily drawn into the needle, causing blockage, which affects extraction efficiency, increases costs, and may damage the needle. At the same time, due to the sharpness of the needle and the uncertainty of the operation, the yolk is easily punctured, leading to contamination of the allantoic fluid and thus affecting the quantity and quality of the allantoic fluid harvested. Utility Model Content

[0005] The purpose of this invention is to provide a chicken embryo allantoic fluid collection device, which solves the technical problems of shell membrane clogging the needle and easy yolk puncture in the existing technology during the chicken embryo allantoic fluid collection process.

[0006] This utility model discloses a device for collecting chicken embryo allantoic fluid, comprising:

[0007] Syringe needles, including

[0008] The needle stalk has a hollow tubular structure.

[0009] The needle plug is located at the rear end of the needle shaft;

[0010] Anti-clogging filter element, fitted around the syringe needle, includes

[0011] A cannula is fitted over the needle shaft.

[0012] A cover is provided at the front end of the sleeve and covers the front end of the needle shaft through an internal receiving cavity. The outer periphery of the cover has multiple liquid inlet holes that communicate with the receiving cavity.

[0013] A connector is located at the rear end of the sleeve and is detachably connected to the needle plug.

[0014] This application utilizes a cover to enclose the front end of the needle stem, taking advantage of its smooth and edgeless outer surface to reduce the risk of yolk breakage during harvesting. This method is convenient, fast, and yields a high harvest, providing favorable conditions for subsequent production. Furthermore, by opening multiple liquid inlet holes on the outside of the cover, the liquid inlet path can be dispersed, thereby reducing the risk of blockage caused by a single channel. Additionally, by installing a sleeve around the needle stem, the cover provides stable support, ensuring a smooth harvesting process. Finally, by incorporating a connector for detachable connection with the needle plug, assembly and disassembly are facilitated, making cleaning and replacement convenient.

[0015] Based on the above technical solution, the solution of this application can be further improved as follows:

[0016] Preferably, the casing has a spherical structure; with this design, the outer surface is smooth, which can reduce the risk of scratching the embryonic tissue and cover a wider angle range, ensuring that there is a liquid inlet channel available no matter how the needle is tilted, and making the volume of the collection cavity larger and the shape more regular, thereby ensuring collection efficiency.

[0017] Preferably, the liquid inlet holes are located in the lower half of the cover and are spaced apart from each other; this design enhances the anti-clogging capability and can better intercept heavier impurities (such as shell membranes, tissue fragments, etc.) that sink with the liquid, preventing them from entering the needle shaft.

[0018] Preferably, the inlet hole has a circular structure; this design ensures that the inlet hole has no sharp edges, so that no turbulence or eddies are generated when the liquid flows through it, thus ensuring uniform flow rate, reducing the risk of impurities accumulating at the inlet hole, reducing the frictional resistance between the liquid and the hole wall, and improving the liquid flow efficiency.

[0019] Preferably, the front end of the needle plug has a frustum, and the smaller end face of the frustum is connected to and coaxially arranged with the needle shaft; by adopting this solution, a tapered transition structure is formed, which can match the outer diameter of the needle shaft, reducing the risk of liquid leakage during collection.

[0020] Preferably, the rear end of the frustum has an annular groove, and the connector includes:

[0021] A cover is fitted onto the smaller end of the frustum.

[0022] Multiple claws are configured and evenly distributed on the top surface of the cover, and can engage with the annular slot. This solution allows for quick assembly and disassembly without tools, significantly improving the ease of assembly, connection stability, and modular adaptability of the device, thus enhancing its practical performance.

[0023] Through the above technical solution, this utility model achieves the following beneficial effects:

[0024] 1. This application uses a cover to cover the front end of the needle stem. The smooth and edgeless outer surface of the cover reduces the risk of yolk breakage during the harvesting process. It is convenient, fast, and yields a high harvest, providing convenient conditions for subsequent production.

[0025] 2. This application reduces the risk of blockage caused by a single channel by opening multiple liquid inlet holes on the outside of the casing, thereby dispersing the liquid inlet path;

[0026] 3. This application provides stable support for the casing by setting a sleeve around the needle shaft, thus ensuring a smooth receiving process;

[0027] 4. This application uses a connector to detachably connect the pin, which facilitates assembly and disassembly, making it convenient for cleaning and replacement. Attached Figure Description

[0028] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0029] Figure 1 This is a front view of the chicken embryo allantoic fluid collection device according to a specific embodiment of the present invention;

[0030] Figure 2 for Figure 1 Front sectional view of the chicken embryo allantoic fluid collection device shown;

[0031] Figure 3 for Figure 1 A schematic diagram of the syringe needle in the chicken embryo allantoic fluid collection device shown;

[0032] Figure 4 for Figure 1 A front cross-sectional view of the anti-clogging filter element in the chicken embryo allantoic fluid collection device shown.

[0033] Explanation of reference numerals in the attached figures:

[0034] 1. Syringe needle; 11. Needle shaft; 12. Needle plug; 121. Frustum; 122. Annular groove;

[0035] 2. Anti-clogging filter element; 21. Sleeve; 22. Cover; 221. Collection cavity; 222. Liquid inlet; 23. Connector; 231. Cover; 232. Claw. Detailed Implementation

[0036] The embodiments of the present invention will now be described in detail with reference to the accompanying drawings. These embodiments are merely illustrative of the present invention and should not be construed as limiting the scope of protection of the present invention.

[0037] First, it should be noted that some directional terms used in the following description to clearly illustrate the technical solution of this utility model, such as the terms "upper," "lower," "front," "rear," "vertical," "horizontal," "top," "bottom," "inner," and "outer," are all derived from the normal orientation of the components in the chicken embryo allantoic fluid collection device. They are only used to facilitate the description of this utility model and simplify the description, and are not intended to indicate or imply that the device or component referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0038] In this application, unless otherwise expressly specified and limited, the terms "installation" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0039] To better understand the above technical solutions, the following will provide a detailed description of the technical solutions in conjunction with the accompanying drawings and specific embodiments.

[0040] Example:

[0041] like Figures 1-4 As shown in the figure, this application discloses a chicken embryo allantoic fluid collection device for extracting allantoic fluid from the chicken embryo allantoic cavity, which can avoid the shell membrane clogging the needle and reduce the risk of yolk rupture, thereby improving the quantity and quality of allantoic fluid collection. Its specific structure includes: a syringe needle 1 and an anti-clogging filter 2.

[0042] Syringe needle 1 includes:

[0043] Needle 11, which has a hollow tubular structure, is used to absorb allantoic fluid;

[0044] The needle plug 12 is located at the rear end of the needle shaft 11 to facilitate connection with aspiration equipment (vacuum pump, syringe, etc.) to ensure stable aspiration of allantoic fluid.

[0045] The anti-clogging filter element 2 is fitted around the syringe needle 1 to prevent the shell membrane from clogging the needle and reduce the risk of yolk breakage. It includes:

[0046] The sleeve 21 is fitted over the needle shaft 11 and is used to provide support for the cover 22;

[0047] The cover 22 is located at the front end of the sleeve 21 and covers the front end of the needle rod 11 through the internal collection cavity 221. The outer periphery of the cover 22 has multiple inlet holes 222 that communicate with the collection cavity 221, so as to allow allantoic fluid to enter the collection cavity 221 from multiple directions, thereby reducing the risk of blockage of a single channel by dispersing the inlet path.

[0048] The connector 23 is located at the rear end of the sleeve 21 and is detachably connected to the needle plug 12, enabling quick assembly and disassembly of the anti-clogging filter 2 and the syringe needle 1, thus facilitating cleaning and replacement.

[0049] This invention, by setting a cover 22 to cover the front end of the needle stem 11, utilizes the smooth and edgeless outer surface of the cover to reduce the risk of yolk breakage during collection, making it convenient, fast, and yielding high harvests, thus providing favorable conditions for subsequent production. Furthermore, by opening multiple liquid inlet holes 222 on the outside of the cover 22, the liquid inlet path can be dispersed, thereby reducing the risk of blockage caused by a single channel. In addition, by setting a sleeve 21 to be fitted over the needle stem 11, the cover 22 provides stable support and ensures a smooth collection process. Finally, by setting a connector 23 to detachably connect to the needle plug 12, it is easy to assemble and disassemble, thus facilitating cleaning and replacement.

[0050] In some embodiments, such as Figure 3-4 As shown, the casing 22 has a spherical structure with a smooth outer surface, which reduces the risk of scratching the embryonic tissue and can cover a wider range of angles, ensuring that there is a liquid inlet channel available no matter how the needle is tilted. It also makes the volume of the collection cavity 221 larger and the shape more regular, thereby ensuring collection efficiency.

[0051] In some embodiments, such as Figure 1 As shown, liquid inlet holes 222 are opened in the lower half of the cover 22 and are spaced apart from each other.

[0052] The above design enhances the anti-clogging capability. By setting the liquid inlet hole 222 in the lower part, heavier impurities (such as shell membranes, tissue fragments, etc.) that sink with the liquid can be better intercepted, preventing them from entering the needle stem 11.

[0053] In some embodiments, such as Figure 1As shown, the liquid inlet hole 222 has a circular structure.

[0054] The above design ensures that the inlet hole 222 has no sharp edges, thus preventing turbulence or eddies when the liquid flows through, ensuring uniform flow rate, reducing the risk of impurities accumulating at the inlet, reducing frictional resistance between the liquid and the hole wall, and improving liquid flow efficiency.

[0055] In some embodiments, such as Figure 3 As shown, the front end of the needle plug 12 has a frustum 121, and the smaller end face of the frustum 121 is connected to and coaxially arranged with the needle shaft 11.

[0056] The above design creates a tapered transition structure that can fit with the outer diameter of the needle shaft 11, reducing the risk of liquid leakage during the collection process.

[0057] Based on the above embodiments, the rear end of the frustum 121 has an annular groove 122, and the connector 23 includes:

[0058] Cover 231 is fitted onto the smaller end of frustum 121.

[0059] Multiple claws 232 are configured and evenly distributed on the top surface of the cover 231, and can engage with the annular slot 122.

[0060] Specifically, the dimensions of the annular groove 122, such as its width and depth, are standardized to match the elastic deformation range of the claw 232, thereby ensuring the stability of the engagement.

[0061] Specifically, multiple claws 232 are evenly distributed on the top surface of the cover 231, which can form multi-point contact, thereby effectively dispersing axial and radial loads and preventing the connector 23 from loosening; and the elastic deformation range of the claws 232 has a safety threshold, which automatically disengages when the external force exceeds the limit, thereby facilitating the disassembly of the anti-clogging filter element 2.

[0062] The above design enables rapid assembly and disassembly without tools, significantly improving the ease of assembly, connection stability, and modular adaptability of the device, thereby enhancing its practical application.

[0063] The working principle of the above technical solution is as follows:

[0064] When aspirating allantoic fluid, the needle plug 12 is connected to the suction device to use negative pressure to aspirate the allantoic fluid. Then, the sleeve 21 is fitted over the needle stem 11, so that the front end of the needle stem 11 extends into the collection cavity 221 of the cover 22. At the same time, it is detachably connected to the needle plug 12 through the connector 23, so that the anti-clogging filter 2 can be kept fixed. Specifically, the operator presses the cover 231, so that the cover 231 is fitted onto the bottom end of the frustum 121, and at the same time, the claw 232 is elastically deformed until it is axially pushed into the annular groove 122 to complete the locking connection.

[0065] Next, the cover 22 is inserted into the allantoic cavity of the chicken embryo, allowing the allantoic fluid to enter the collection cavity 221 through the various inlet holes 222. The fluid is then drawn in by the tip of the needle shank 11, which filters and blocks the eggshell membrane, preventing blockage. Even if some inlet holes 222 are blocked by the eggshell membrane, the overall suction process remains unaffected. Furthermore, because the outer surface of the cover 22 is smooth and without sharp edges, it will not damage the yolk even upon contact.

[0066] Numerous specific details are set forth in this specification. However, it will be understood that embodiments of this invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this specification.

[0067] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0068] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and not to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model, and they should all be covered within the scope of the claims and specification of this utility model.

Claims

1. A device for collecting chicken embryo allantoic fluid, characterized in that, include: Syringe needles, including The needle stalk has a hollow tubular structure. The needle plug is located at the rear end of the needle shaft; Anti-clogging filter element, fitted around the syringe needle, includes A cannula is fitted over the needle shaft. A cover is provided at the front end of the sleeve and covers the front end of the needle shaft through an internal receiving cavity. The outer periphery of the cover has multiple liquid inlet holes that communicate with the receiving cavity. A connector is located at the rear end of the sleeve and is detachably connected to the needle plug.

2. The chicken embryo allantoic fluid collection device according to claim 1, characterized in that, The casing has a spherical structure.

3. The chicken embryo allantoic fluid collection device according to claim 2, characterized in that, The liquid inlet holes are located in the lower half of the cover and are spaced apart from each other.

4. The chicken embryo allantoic fluid collection device according to claim 1, characterized in that, The liquid inlet hole has a circular structure.

5. The chicken embryo allantoic fluid collection device according to claim 1, characterized in that, The needle plug has a frustum at its front end, and the smaller end face of the frustum is connected to and coaxially arranged with the needle shaft.

6. The chicken embryo allantoic fluid collection device according to claim 5, characterized in that, The rear end of the frustum has an annular groove, and the connector includes: A cover is fitted onto the smaller end of the frustum. Multiple claws are configured and evenly distributed on the top surface of the cover, and can engage with the annular slot.

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