Lopinavir centrifugal device

By designing a lopinavir centrifuge unit with centrifugation, scraping, and storage units, the problems of poor centrifugation effect and inconvenient material removal in existing devices have been solved, achieving full separation and convenient removal of materials and improving centrifugation efficiency.

CN224114227UActive Publication Date: 2026-04-14XIAMEN SICHONG BIOPHARMACEUTICAL TECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
XIAMEN SICHONG BIOPHARMACEUTICAL TECHNOLOGY CO LTD
Filing Date
2025-05-13
Publication Date
2026-04-14

AI Technical Summary

Technical Problem

Existing lopinavir centrifuge devices have poor centrifugation separation effect and are inconvenient to remove materials.

Method used

A lopinavir centrifuge device was designed, comprising a centrifugation unit, a scraping unit, and a storage unit. The device uses a rotating motor to drive the connecting rod and scraping plate to separate materials, and utilizes the partition and positioning groove of the storage cylinder to prevent material accumulation and facilitate material removal.

Benefits of technology

This method enables thorough centrifugation and convenient removal of materials, improves centrifugal separation efficiency, and reduces material accumulation and incomplete separation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a lopinavir centrifugal device, which belongs to the technical field of raw material separation, and comprises a centrifugal unit, a scraping unit and a material storage unit, the centrifugal unit comprises a rotating motor, the rotating motor is arranged on a support seat, the top of the rotating motor is provided with a rotating shaft, and the rotating shaft is arranged on the support seat. A connecting rod is fixedly connected to the top of the rotating shaft, a centrifugal cylinder is arranged on the connecting rod, a threaded hole is formed in the bottom of the centrifugal cylinder, the connecting rod is connected with the centrifugal cylinder through the threaded hole, and a plurality of discharging holes are formed in the inner wall of the centrifugal cylinder; the scraping unit comprises a connecting pipe extending into the centrifugal barrel, a scraping plate is fixedly installed on the outer wall of the connecting pipe, a discharging groove is formed in the side face of the scraping plate, and the top of the connecting pipe is connected with a driving shaft of a driving motor. And the condition of insufficient material accumulation and separation is reduced.
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Description

Technical Field

[0001] This utility model relates to the field of raw material separation technology, specifically a lopinavir centrifuge device. Background Technology

[0002] Lopinavir, with the molecular formula C37H48N4O5, is an HIV protease inhibitor and an antiretroviral drug used to treat HIV-1 infection in adults and pediatric patients over 6 months of age. The production process of lopinavir requires the extraction of necessary elements from various raw materials. In order to maximize the proportion of extracted elements, the raw materials are usually crushed and then sieved.

[0003] The crushed raw materials are usually centrifuged to separate the finely crushed and uncrushed materials for re-crushing. However, the existing centrifugation devices have poor centrifugation separation effect and are inconvenient to remove.

[0004] Therefore, it is necessary to propose a centrifuge device that has a better centrifugation effect and makes it convenient to remove the centrifuged material. Utility Model Content

[0005] The purpose of this invention is to provide a lopinavir centrifuge device to at least partially solve the above-mentioned technical problems, so as to facilitate the full centrifugation of materials and the removal of centrifuged materials.

[0006] To achieve the above objectives, this utility model provides the following technical solution: it includes a centrifugal unit, a scraping unit, and a storage unit. The centrifugal unit includes a rotating motor, which is mounted on a support base. A rotating shaft is mounted on the top of the rotating motor, and a connecting rod is fixedly connected to the top of the rotating shaft. A centrifugal cylinder is mounted on the connecting rod, and a threaded hole is provided at the bottom of the centrifugal cylinder. The connecting rod is connected to the centrifugal cylinder through the threaded hole, and several discharge holes are provided on the inner wall of the centrifugal cylinder.

[0007] The scraping unit includes a connecting pipe extending into the centrifuge cylinder, a scraping plate fixedly installed on the outer wall of the connecting pipe, a discharge groove opened on the side of the scraping plate, and the top of the connecting pipe connected to the drive shaft of the drive motor.

[0008] The storage unit includes a storage cylinder sleeved outside the centrifuge cylinder. A support foot is fixedly installed at the bottom of the storage cylinder. An insertion hole for the connecting rod to pass through is opened at the bottom of the storage cylinder. A circular positioning groove is opened on the lower surface inside the storage cylinder. A partition plate fixedly connected to the centrifuge cylinder is provided above the positioning groove. A cover plate is provided on the top of the storage cylinder. The drive motor is located on the top of the cover plate.

[0009] Furthermore, the rotating motor is located directly below the centrifuge cylinder and the storage cylinder, and the connecting rod does not contact the storage cylinder.

[0010] Furthermore, the upper surface area of ​​the insertion hole is larger than the upper surface area of ​​the connecting rod, the outer wall of the connecting rod is threaded, and the connecting rod is threadedly connected to the threaded hole.

[0011] Furthermore, the end of the scraper near the inner wall of the centrifuge cylinder is arc-shaped, and the scraper does not contact the inside of the centrifuge cylinder.

[0012] Furthermore, the discharge trough passes through the scraper plate, and the connecting pipe does not contact the inner wall of the centrifuge cylinder.

[0013] Furthermore, the partition does not contact the inner wall of the storage cylinder.

[0014] Furthermore, the connecting pipe is located at the center of the centrifuge cylinder, and the rotation speed of the rotating motor is different from that of the drive motor.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0016] 1. In use, the material is placed into the centrifuge cylinder from above the storage cylinder. The rotating motor drives the connecting rod to rotate, which in turn drives the centrifuge cylinder to rotate. The material inside the centrifuge cylinder is centrifuged, and the broken material is thrown out from several discharge holes. To prevent the material from adhering and accumulating on the centrifuge cylinder due to centrifugal force, the drive motor drives the connecting pipe and scraper to rotate. The scraper contacts the accumulated material and breaks it down onto the centrifuge cylinder for centrifugation. The drive motor drives the scraper to rotate in both directions, and its discharge trough can keep the material from accumulating near the scraper cylinder, effectively preventing the accumulation of material under centrifugal force. Through the above methods, the material is separated more fully during the centrifugation process, reducing the situation of insufficient separation due to material accumulation.

[0017] 2. In use, the centrifuge cylinder throws the crushed material from the discharge hole into the storage cylinder. Since the storage cylinder is fixed, the thrown material will contact the inner wall of the storage cylinder and fall down. The connecting rod and the bottom insertion hole are isolated by the partition to prevent the material from contacting them. The positioning groove is designed as a recess so that when the material accumulates, it will not pass too much through the gap between the partition and the positioning groove. When it is necessary to remove the material, the centrifuge cylinder and the storage cylinder are taken out together. After opening the cover, the centrifuge cylinder is taken out for cleaning. The material that is not fully crushed inside is crushed again and then centrifuged. Then the storage cylinder is pulled up to store the separated material stored inside for later use, which facilitates the centrifugal separation and packaging of materials. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a cross-sectional view of the overall structure of this embodiment;

[0020] Figure 2 This is an enlarged schematic diagram of the structure at point A in this embodiment;

[0021] Figure 3 This is a schematic diagram of the overall structure of this embodiment during assembly and use.

[0022] The attached diagram lists the components represented by each number as follows:

[0023] 100. Centrifuge unit; 110. Rotary motor; 111. Rotating shaft; 120. Connecting rod; 130. Centrifuge cylinder; 131. Threaded hole; 132. Discharge hole; 140. Support base;

[0024] 200, Scraping unit; 210, Drive motor; 211, Drive shaft; 220, Connecting pipe; 221, Scraping plate; 2211, Discharge chute;

[0025] 300, storage unit; 310, storage cylinder; 311, support foot; 312, insertion hole; 313, positioning groove; 320, partition; 330, cover plate. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0027] Please see Figure 1-3This utility model provides a technical solution: a lopinavir centrifuge device, including a centrifugation unit 100, a scraping unit 200, and a storage unit 300. The centrifugation unit 100 includes a rotating motor 110, which is located directly below the centrifuge cylinder 130 and the storage cylinder 310. The rotating motor 110 is mounted on a support base 140. A rotating shaft 111 is provided on the top of the rotating motor 110, and a connecting rod 120 is fixedly connected to the top of the rotating shaft 111. The centrifuge cylinder 130 is mounted on the connecting rod 120. The centrifuge cylinder 130 has a threaded hole 131 at its bottom. The outer wall of the connecting rod 120 is threaded. The connecting rod 120 is threaded to the threaded hole 131. The connecting rod 120 is connected to the centrifuge cylinder 130 through the threaded hole 131. The rotating motor 110 and its rotating shaft 111 can fully drive the centrifuge cylinder 130 to rotate and maintain its stable rotation. The threaded hole 131 at the bottom of the centrifuge cylinder 130 makes it easy to connect and disconnect the connecting rod 120 from it, that is, it is easy to assemble and disassemble the centrifuge cylinder 130 from the rotating mechanism.

[0028] The inner wall of the centrifuge cylinder 130 is provided with several discharge holes 132. The discharge holes 132 are narrow discharge holes 132, which are only large enough for materials that meet the crushing specifications to pass through. Materials larger than the diameter of the discharge hole 132 cannot pass through, that is, they are unqualified materials and need to be crushed again.

[0029] See Figure 1 In a preferred embodiment, the scraping unit 200 includes a connecting pipe 220 extending into the centrifuge cylinder 130. A scraping plate 221 is fixedly installed on the outer wall of the connecting pipe 220. The connecting pipe 220 is located at the center of the centrifuge cylinder 130. The top of the connecting pipe 220 is connected to the drive shaft 211 of the drive motor 210.

[0030] The connecting pipe 220 is located at the center of the centrifuge cylinder 130. When the drive motor 210 drives the connecting pipe 220 and the scraper 221 to rotate, the scraper 221 rotates in a circular motion, which can fully contact the material accumulated on the inner wall of the centrifuge cylinder 130, break up the accumulated material, improve centrifugation efficiency, and prevent the failure to fully distinguish between qualified and unqualified materials.

[0031] The rotation speeds of the rotating motor 110 and the drive motor 210 are different. The end of the scraper 221 near the inner wall of the centrifuge cylinder 130 is arc-shaped, and the scraper 221 does not contact the inside of the centrifuge cylinder 130. The arc shape at one end of the scraper 221 can prevent wear and tear on the machine caused by rubbing against the centrifuge cylinder 130 during rotation. The arc shape can also reduce resistance, and the material in contact with it cannot stay to the maximum extent. A discharge groove 2211 is provided on the side of the scraper 221. The discharge groove 2211 passes through the scraper 221. The connecting pipe 220 does not contact the inner wall of the centrifuge cylinder 130. The discharge groove 2211 allows the material remaining on the scraper 221 to be thrown out to a certain extent, reducing the material adhering to the scraper 221 and further improving the degree of material separation.

[0032] See Figure 1-3 In a further preferred embodiment, the storage unit 300 includes a storage cylinder 310 sleeved outside the centrifuge cylinder 130, and a support foot 311 is fixedly installed at the bottom of the storage cylinder 310.

[0033] The storage cylinder 310 can be placed directly on the support base 140 via the support foot 311 without the need for other structural support. Furthermore, structures such as the centrifuge cylinder 130 can be installed on the storage cylinder 310, making it easy to disassemble and assemble different structures, and ensuring that they do not affect each other when used simultaneously.

[0034] The bottom of the storage cylinder 310 is provided with a insertion hole 312 for the connecting rod 120 to pass through. The connecting rod 120 does not contact the storage cylinder 310, and the upper surface area of ​​the insertion hole 312 is larger than the upper surface area of ​​the connecting rod 120.

[0035] When the connecting rod 120 passes through the insertion hole 312 into the storage cylinder 310, the connecting rod 120 can be connected to the threaded hole 131, thus connecting the connecting rod 120 to the centrifuge cylinder 130. The rotation of the rotary motor 110 can be transmitted through the connecting rod 120, allowing the centrifuge cylinder 130 to perform centrifugal separation. At the same time, the insertion hole 312 facilitates the insertion of the connecting rod 120, further facilitating the placement and removal of the storage cylinder without affecting the normal operation of the centrifuge cylinder 130.

[0036] See Figure 1 and Figure 2 A circular positioning groove 313 is provided on the lower surface inside the storage cylinder 310. A partition 320 is fixedly connected to the centrifuge cylinder 130 above the positioning groove 313. The partition 320 does not contact the inner wall of the storage cylinder 310. A cover plate 330 is provided on the top of the storage cylinder 310, and the drive motor 210 is located on the top of the cover plate 330.

[0037] The partition 320 isolates the connecting rod 120 from the bottom insertion hole 312, preventing materials from contacting it and further preventing materials from falling from the insertion hole 312. The positioning groove 313 is designed as a recess, so that when materials accumulate, they will not pass too much through the gap between the partition 320 and the positioning groove 313.

[0038] In the description of this utility model, it should be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "side", "top", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0039] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0040] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A lopinavir centrifuge device, comprising a centrifugation unit (100), a scraping unit (200), and a storage unit (300), characterized in that: The centrifugal unit (100) includes a rotating motor (110), which is mounted on a support base (140). A rotating shaft (111) is mounted on the top of the rotating motor (110), and a connecting rod (120) is fixedly connected to the top of the rotating shaft (111). A centrifugal cylinder (130) is mounted on the connecting rod (120), and a threaded hole (131) is provided at the bottom of the centrifugal cylinder (130). The connecting rod (120) is connected to the centrifugal cylinder (130) through the threaded hole (131), and a plurality of discharge holes (132) are provided on the inner wall of the centrifugal cylinder (130). The scraping unit (200) includes a connecting pipe (220) extending into the centrifuge cylinder (130), a scraping plate (221) is fixedly installed on the outer wall of the connecting pipe (220), a discharge groove (2211) is provided on the side of the scraping plate (221), and the top of the connecting pipe (220) is connected to the drive shaft (211) of the drive motor (210). The storage unit (300) includes a storage cylinder (310) sleeved outside the centrifuge cylinder (130). A support foot (311) is fixedly installed at the bottom of the storage cylinder (310). An insertion hole (312) for the connecting rod (120) to pass through is opened at the bottom of the storage cylinder (310). A circular positioning groove (313) is opened on the lower surface inside the storage cylinder (310). A partition plate (320) fixedly connected to the centrifuge cylinder (130) is provided above the positioning groove (313). A cover plate (330) is provided at the top of the storage cylinder (310). The drive motor (210) is located on the top of the cover plate (330).

2. The lopinavir centrifuge device according to claim 1, characterized in that: The rotating motor (110) is located directly below the centrifuge cylinder (130) and the storage cylinder (310), and the connecting rod (120) does not contact the storage cylinder (310).

3. A lopinavir centrifuge device according to claim 2, characterized in that: The upper surface area of ​​the insertion hole (312) is larger than the upper surface area of ​​the connecting rod (120). The outer wall of the connecting rod (120) is threaded, and the connecting rod (120) is threadedly connected to the threaded hole (131).

4. A lopinavir centrifuge device according to claim 1, characterized in that: The scraper (221) is arc-shaped at one end near the inner wall of the centrifuge cylinder (130), and the scraper (221) does not contact the inside of the centrifuge cylinder (130).

5. A lopinavir centrifuge device according to claim 4, characterized in that: The discharge trough (2211) passes through the scraper (221), and the connecting pipe (220) does not contact the inner wall of the centrifuge cylinder (130).

6. A lopinavir centrifuge device according to claim 1, characterized in that: The partition (320) does not contact the inner wall of the storage cylinder (310).

7. A lopinavir centrifuge device according to claim 1, characterized in that: The connecting pipe (220) is located at the center of the centrifuge tube (130), and the rotation speed of the rotating motor (110) is different from that of the drive motor (210).