Liquid adding device

Abstract

The utility model discloses a liquid adding device, relates to the field of laboratory instruments, and aims to solve the problem that the surface flatness of an adsorbent column is damaged due to traditional direct liquid adding. According to the liquid adding device, a first flow guide component comprises a connecting pipe with one end leading in liquid and a drainage piece, the drainage piece is arranged in the connecting pipe, a circulation gap is formed between the drainage piece and the inner wall of the connecting pipe, and the drainage piece is used for draining the liquid to the circulation gap to flow out; one end of the second flow guide part is communicated with the other end of the connecting pipe, the second flow guide part is a hollow cylinder with a conical inner wall close to one end of the connecting pipe, and the other end of the second flow guide part is close to the inner wall of the chromatographic column and enables liquid to flow out along the edge of the bottom end. After being poured, liquid falls to the drainage piece along the connecting pipe and is blocked by the drainage piece, and downwards flows to the conical surface of the second flow guide part from the circulating gap by clinging to the inner wall of the connecting pipe, so that the speed of the liquid flowing to the edge of the bottom end of the second flow guide part is slowed down, and the damage to the surface flatness of an adsorbent column caused by the liquid flowing into the chromatographic column after liquid adding is reduced.

Description

Technical Field

[0001] This utility model relates to the field of laboratory experimental instruments, specifically to a liquid addition device. Background Technology

[0002] Column chromatography is commonly used to separate and purify target components and is an indispensable separation method in chemical experiments. It is a separation method that utilizes the partition equilibrium mechanism. The separation principle of column chromatography is that different substances have different adsorption capacities on the stationary phase, and different components are separated by elution with an eluent. The specific process of column chromatography usually includes column packing, sample loading, elution, and collection of the eluent.

[0003] In the elution process, eluent needs to be added to the stationary phase. Traditional methods of adding eluent usually involve using disposable droppers or funnels. The liquid flows down from the center and cannot flow down the inner wall of the chromatography column, resulting in a large impact force when the liquid falls. This damages the smoothness of the adsorbent column surface at the bottom of the chromatography column, making the adsorbent column surface uneven. Consequently, the active centers on the adsorbent column surface are unevenly distributed, reducing the separation efficiency of the adsorbent. Utility Model Content

[0004] The purpose of this invention is to provide a liquid addition device to reduce the damage to the surface smoothness of the adsorbent column inside the chromatography column during the liquid addition process.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a liquid dispensing device, comprising:

[0006] The first flow guiding component includes a connecting pipe and a flow guide. One end of the connecting pipe is used to introduce liquid, and the flow guide is disposed inside the connecting pipe. There is a flow gap between the flow guide and the inner wall of the connecting pipe. The flow guide is used to guide the liquid to flow out through the flow gap.

[0007] The second flow guide component is connected to the other end of the connecting tube at one end. The second flow guide component is a hollow cylinder, and the inner wall of the end of the hollow cylinder near the connecting tube is a conical surface. The other end of the second flow guide component is used to approach the inner wall of the chromatography column and allow the liquid to flow out along the bottom edge of the second flow guide component.

[0008] Optionally, in the above-mentioned liquid addition device, the drainage component includes a herringbone baffle, a U-shaped baffle, or a conical plate with a serrated structure at the bottom edge.

[0009] Optionally, in the above-mentioned liquid addition device, the width of the flow gap is 0.5 mm to 3 mm.

[0010] Optionally, in the above-mentioned liquid addition device, the outer wall of the second flow guiding component has a plurality of through holes arranged at intervals along its circumferential direction and / or axial direction. The through holes are used to disperse a portion of the liquid to flow out through the outer wall of the second flow guiding component.

[0011] Optionally, in the above-mentioned liquid adding device, the through hole includes a circular hole, an elliptical hole, or a polygonal hole.

[0012] Optionally, in the above-mentioned liquid addition device, multiple through holes are distributed along the axial direction of the second flow guide component in the area of ​​the second flow guide component near the end of the connecting pipe in 2 / 3 of the region.

[0013] Optionally, in the above-mentioned liquid addition device, the bottom edge of the second flow guiding component is provided with a flow guiding lip, which extends outward by bending.

[0014] Optionally, in the above-mentioned liquid addition device, the edge of the guide lip away from the second guide component has a serrated structure.

[0015] Optionally, the above-mentioned liquid adding device also includes a funnel, with an inlet and an outlet at each end of the funnel, and the outlet is connected to the end of the connecting pipe away from the second guide component.

[0016] Optionally, in the above-mentioned liquid addition device, the first flow guiding component and the second flow guiding component are integrally formed structures;

[0017] Alternatively, the first and second flow guiding components can be connected by snap-fit ​​or threaded connection.

[0018] Compared with the prior art, when using the above technical solution, the operator places the other end of the second flow guide component away from the first flow guide component close to the inner wall of the chromatography column, and then pours liquid into the connecting tube of the first flow guide component. The liquid falls axially along the connecting tube to the guide component. Due to the obstruction of the guide component, the speed of the liquid flow to the bottom edge of the second flow guide component is slowed down. The liquid flows out continuously downward from the flow gap between the guide component and the inner wall of the connecting tube, adhering to the inner wall of the connecting tube, to the second flow guide component. Then, the liquid flows continuously along the conical surface of the inner wall of the hollow column of the second flow guide component close to the connecting tube, so that the poured liquid can slowly flow out from the bottom edge of the second flow guide component, and the outflowing liquid can just flow along the inner wall of the chromatography column into the chromatography column, reducing the damage to the surface flatness of the adsorbent column inside the chromatography column during the liquid addition process. Attached Figure Description

[0019] The accompanying drawings, which are included to provide a further understanding of the present invention and constitute a part of this invention, illustrate exemplary embodiments of the present invention and, together with the description thereof, serve to explain the present invention and do not constitute an undue limitation thereof. In the drawings:

[0020] Figure 1 This is a schematic diagram of the overall structure of a liquid dispensing device provided in an embodiment of this utility model;

[0021] Figure 2 for Figure 1 Axial sectional view of the first type of drainage element in the structure;

[0022] Figure 3 for Figure 1 Axial sectional view of the second type of drainage component in the structure;

[0023] Figure 4 for Figure 1 Axial sectional view of the third type of drainage component in the structure;

[0024] Figure 5 for Figure 1 A front view showing the circular hole and the guide lip.

[0025] Figure 6 for Figure 1 A front view showing the oval hole and guide lip in the center;

[0026] Figure 7 for Figure 1 Bottom view when the edge of the middle guide lip has a serrated structure and a second type of guide element is used.

[0027] Figure label:

[0028] 1-First flow guiding component; 11-Connecting pipe; 12-Flow guiding component; 2-Second flow guiding component; 21-Through hole; 22-Flow guiding lip; 3-Function funnel; 4-Flow gap. Detailed Implementation

[0029] To make the technical problems, technical solutions, and beneficial effects of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0030] It should be noted that when a component is referred to as being "fixed to" or "set on" another component, it can be directly on or indirectly on that other component. When a component is referred to as being "connected to" another component, it can be directly connected to or indirectly connected to that other component.

[0031] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified. "Several" means one or more, unless otherwise explicitly specified.

[0032] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0033] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0034] like Figures 1-7 As shown in the figure, the liquid addition device provided in this embodiment of the present invention includes: a first flow guiding component 1 and a second flow guiding component 2.

[0035] The first flow guiding component 1 includes a connecting pipe 11 and a flow guide 12. One end of the connecting pipe 11 is used to introduce liquid, and the flow guide 12 is disposed inside the connecting pipe 11. There is a flow gap 4 between the flow guide 12 and the inner wall of the connecting pipe 11. The flow guide 12 is used to guide the liquid to flow out through the flow gap 4. One end of the second flow guiding component 2 is connected to the other end of the connecting pipe 11. The second flow guiding component 2 is a hollow column, and the inner wall of the hollow column near the connecting pipe 11 is a conical surface. The other end of the second flow guiding component 2 is used to approach the inner wall of the chromatography column and allow the liquid to flow out along the bottom edge of the second flow guiding component 2.

[0036] In specific implementation, such as Figure 1 As shown, after the operator places the other end of the second flow guide 2 away from the first flow guide 1 close to the inner wall of the chromatography column, liquid is poured in from the connecting tube 11 of the first flow guide 1. The liquid falls axially along the connecting tube 11 to the guide 12. Due to the obstruction of the guide 12, the speed of the liquid flow to the bottom edge of the second flow guide 2 is slowed down. The liquid flows out continuously from the flow gap 4 between the guide 12 and the inner wall of the connecting tube 11, adhering to the inner wall of the connecting tube 11, to the second flow guide 2. Then, the liquid flows continuously along the conical surface of the inner wall of the hollow column of the second flow guide 2 close to the connecting tube 11, so that the poured liquid can slowly flow out from the bottom edge of the second flow guide 2. The outflowing liquid can just flow along the inner wall of the chromatography column into the chromatography column, reducing the damage to the surface flatness of the adsorbent column inside the chromatography column during the liquid addition process.

[0037] like Figures 1-4 As shown, it should be noted that the conical surface of the inner wall of the hollow cylinder near the connecting pipe 11 is a conical surface that is inclined downward along the horizontal plane in the axial direction of the first flow guide component 1. That is, the inner wall diameter of the conical surface near the first flow guide component 1 is smaller than the inner wall diameter of the conical surface near the second flow guide component 2. As long as the connecting pipe 11 and the hollow cylinder can be smoothly connected through the conical surface, during the process of the liquid flowing from the first flow guide component 1 to the second flow guide component 2, it can continuously and slowly flow along the inner wall of the connecting pipe 11, the conical surface and the inner wall of the hollow cylinder to the bottom edge of the second flow guide component 2 and then flow out.

[0038] like Figure 2 , Figure 3 , Figure 4 and Figure 7 As shown, specifically in this embodiment, the drainage component 12 includes a herringbone baffle, a U-shaped baffle, or a conical plate with a serrated structure at the bottom edge. When the guide member 12 is a herringbone baffle, the guide member 12 is formed by two baffles crossing each other to form a herringbone shape inside the connecting pipe 11. The four ends of each baffle are fixedly connected to the inner wall of the connecting pipe 11, forming a flow gap 4. When the guide member 12 is a U-shaped baffle, the U-shaped baffle has a U-shaped groove. The axis of the U-shaped groove is relatively parallel to the pipe diameter direction of the connecting pipe 11, and the opening direction of the U-shaped groove faces the second guide member 2. The four ends of the U-shaped baffle are fixedly connected to the inner wall of the connecting pipe 11, forming a flow gap 4. When the guide member 12 is a conical plate with a serrated structure at the bottom edge, the tip of the conical plate faces the end of the connecting pipe 11 where the liquid is introduced. The serrated structure has multiple protruding ends at the edge. Each protruding end is fixedly connected to the inner wall of the connecting pipe 11, forming a flow gap 4 at the serrated structure. Of course, the flow guide 12 can also adopt other flow guiding structures, as long as the bottom edge of the flow guide structure can form a flow gap 4 after being fixedly connected to the inner wall of the connecting tube 11. The flow guide 12 forms a certain obstruction effect on the liquid poured into the connecting tube 11. After passing through the surface of the flow guide 12, the liquid is diverted to the flow gap 4 and flows out, so that the liquid can flow along the inner wall of the connecting tube 11. When flowing out to the chromatography column, the liquid falls along the bottom edge, reducing the risk of the liquid falling from the area near the axis of the connecting tube 11 and damaging the surface flatness of the adsorbent stored at the bottom of the chromatography column.

[0039] like Figure 2 and Figure 3As shown, specifically in this embodiment, the width of the flow gap 4 is 0.5mm to 3mm. For example, the width L of the flow gap 4 can be 0.5mm, 1mm, 2mm, 3mm, etc. When the width L of the flow gap 4 is greater than 0.5mm, it can ensure that the droplets pass smoothly through the flow gap 4 and ensure the flow rate of the liquid. When the width of the flow gap 4 is less than 3mm, it allows the liquid to continue flowing along the inner wall of the connecting tube 11 after passing through the flow gap 4, avoiding the risk that a small amount of liquid might fall from the middle area of ​​the connecting tube 11 into the chromatography column due to the excessive width of the flow gap 4, thus damaging the surface flatness of the adsorbent column stored at the bottom of the chromatography column.

[0040] like Figure 5 and Figure 6 As shown, specifically in this embodiment, the outer wall of the second flow guiding component 2 has a plurality of through holes 21 spaced apart along its circumferential direction and / or axial direction. The through holes 21 are used to disperse a portion of the liquid to flow out through the outer wall of the second flow guiding component 2. For example, the through holes 21 can be arranged in 2 rows, 3 rows, 5 rows, etc., spaced apart axially. The through holes 21 can also be arranged in 3 columns, 5 columns, 8 columns, etc., spaced apart along the circumferential direction of the outer wall of the second flow guiding component 2. The through holes 21 between adjacent rows or columns can also be staggered. Of course, the multiple through holes 21 can also adopt other arrangement methods, as long as the interval between two adjacent through holes 21 is ensured. When the liquid flows through the conical surface to the inner wall of the hollow column, because the hollow column is provided with multiple through holes 21, part of the liquid flows through the through holes 21 to the outer wall of the hollow column, while the other part of the liquid continues to flow along the inner wall of the hollow column. The structure of the through holes 21 guides and disperses the flow speed of the liquid, and finally flows out at the bottom edge of the second guide component 2, reducing the impact force when the liquid flows out.

[0041] like Figure 5 and Figure 6 As shown, specifically in this embodiment, the through hole 21 includes a circular hole, an elliptical hole, or a polygonal hole. For example, the shape of the through hole 21 can be circular, elliptical, or polygonal. When the through hole 21 is circular, the diameter of the circular hole can be 3mm to 5mm; when the through hole 21 is elliptical, the major axis of the elliptical hole can be 5mm to 8mm, and the minor axis of the elliptical hole can be 3mm to 4mm. Different shapes of through holes 21 allow a portion of the liquid to flow through the through hole 21 to the outer wall of the hollow column, while another portion of the liquid continues to flow along the inner wall of the hollow column. The structure of the through hole 21 guides and disperses the liquid, thereby reducing the speed of the liquid flow.

[0042] like Figure 5 and Figure 6As shown, specifically in this embodiment, multiple through holes 21 are distributed along the axial direction of the second flow guide 2 in the region of the second flow guide 2 near the end 2 / 3 of the connecting pipe 11. This arrangement allows the liquid to preferentially flow through the upper region of the second flow guide 2, where the flow velocity is reduced by the structure of the through holes 21, before flowing through the smooth lower region where no through holes 21 are provided. This reduces fluctuations after liquid diversion, allowing the liquid to flow smoothly out along the bottom edge of the second flow guide 2, ensuring the stability of the liquid outflow process.

[0043] like Figure 5 and Figure 6 As shown, further, in this embodiment, the bottom edge of the second flow guiding component 2 is provided with a flow guiding lip 22, which extends outward by bending. The surface of the flow guiding lip 22 is arc-shaped, and the radius of curvature R of the arc of the flow guiding lip 22 can be 4mm to 6mm, i.e., the radius of curvature R of the arc of the flow guiding lip 22 can be 4mm, 5mm, or 6mm, etc., as long as the liquid can flow smoothly out through the flow guiding lip 22. When the liquid is diverted through the through hole 21, it flows through the flow guiding lip 22. The arc-shaped guiding effect of the surface of the flow guiding lip 22 can reduce the resistance of the liquid flow on the flow guiding lip 22, so that the liquid on both the outer and inner walls of the second flow guiding component 2 can flow smoothly and steadily out along the bottom edge of the second flow guiding component 2, improving the liquid addition efficiency of the liquid adding device.

[0044] like Figure 7As shown, specifically, in this embodiment, the edge of the guide lip 22 away from the second guide component 2 has a serrated structure. The outline shape of each serrated unit can be semi-circular, triangular, rectangular, or polygonal, as long as the spacing of multiple serrated units ensures smooth liquid flow. When the edge of the guide lip 22 away from the second guide component 2 has a serrated structure, the diameter D at the edge of the serrated structure needs to be equal to the inner wall diameter of the chromatography column. In this case, since a flow hole 21 can be formed between two adjacent serrated units of the serrated structure, the edge of the serrated structure, while tightly adhering to the inner wall of the chromatography column, still ensures that the liquid flows smoothly through the flow hole 21 to the surface of the adsorbent column stored at the bottom of the chromatography column, ensuring the smooth progress of the experiment; or, when the edge of the guide lip 22 away from the second guide component 2 has a serrated structure, the diameter D at the edge of the serrated structure... The diameter of the serrated structure is 1mm to 6mm smaller than that of the inner wall of the chromatography column. That is, the gap between the edge of the serrated structure and the inner wall of the chromatography column is equal to the width of the flow gap 4. At this time, since there is no contact between the guide lip 22 and the inner wall of the chromatography column, the operator needs to hold and fix the liquid addition device to ensure the smooth progress of the experiment. The serrated structure of the edge of the guide lip 22 allows the liquid to flow through the edge of the lip to the inner wall of the chromatography column, and continue to flow down the inner wall of the chromatography column to the surface of the adsorbent column stored at the bottom of the chromatography column, reducing the damage to the surface smoothness of the adsorbent column inside the chromatography column during the liquid addition process.

[0045] like Figure 1 As shown, specifically in this embodiment, the liquid adding device further includes a funnel 3, with an inlet and an outlet at each end. The outlet is connected to the end of the connecting pipe 11 furthest from the second guide component 2. By pouring liquid into the inlet of the funnel 3, splashing of liquid during pouring is avoided, ensuring that the liquid flows smoothly into the connecting pipe 11, which facilitates operation.

[0046] In some embodiments, the first flow guiding component 1 and the second flow guiding component 2 are integrally formed; this configuration reduces the installation steps of the first flow guiding component 1 and the second flow guiding component 2, making operation more convenient.

[0047] In other embodiments, the first flow guiding component 1 and the second flow guiding component 2 are connected by snap-fit ​​or threaded connection. Of course, other detachable connection methods can also be used between the first flow guiding component 1 and the second flow guiding component 2, as long as the sealing of the connection between the first flow guiding component 1 and the second flow guiding component 2 is ensured. When a detachable connection method is adopted, the operator can select the corresponding diameter of the first flow guiding component 1 and the second flow guiding component 2 for docking according to the actual different diameter chromatography columns to meet the experimental requirements, which facilitates the installation and disassembly of the first flow guiding component 1 and the second flow guiding component 2 and improves the flexibility of the liquid addition device.

[0048] In the description of the above embodiments, specific features, structures, materials, or characteristics may be combined in any suitable manner in one or more embodiments or examples.

[0049] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the protection scope of the claims.

Claims

1. A liquid dispensing device, characterized in that, include: The first flow guiding component includes a connecting tube and a flow guide. One end of the connecting tube is used to introduce liquid, and the flow guide is disposed inside the connecting tube. There is a flow gap between the flow guide and the inner wall of the connecting tube. The flow guide is used to guide the liquid to flow out through the flow gap. The second flow guiding component has one end connected to the other end of the connecting tube. The second flow guiding component is a hollow cylinder, and the inner wall of the hollow cylinder near the connecting tube is a conical surface. The other end of the second flow guiding component is used to approach the inner wall of the chromatography column and allow the liquid to flow out along the bottom edge of the second flow guiding component.

2. The liquid addition device according to claim 1, characterized in that, The drainage component includes a herringbone baffle, a U-shaped baffle, or a conical plate with a serrated structure at the bottom edge.

3. The liquid addition device according to claim 1 or 2, characterized in that, The width of the flow gap is 0.5mm to 3mm.

4. The liquid addition device according to claim 1, characterized in that, The outer wall of the second flow guide component has a plurality of through holes spaced apart along its circumferential direction and / or axial direction. The through holes are used to disperse part of the liquid to flow out through the outer wall of the second flow guide component.

5. The liquid addition device according to claim 4, characterized in that, The through hole includes a circular hole, an elliptical hole, or a polygonal hole.

6. The liquid addition device according to claim 4, characterized in that, The plurality of through holes are distributed along the axial direction of the second flow guide component in the region of the second flow guide component near one end of the connecting pipe (2 / 3).

7. The liquid addition device according to claim 1, characterized in that, The bottom edge of the second flow guiding component is provided with a flow guiding lip, which extends outward by bending.

8. The liquid addition device according to claim 7, characterized in that, The edge of the guide lip away from the second guide component has a serrated structure.

9. The liquid addition device according to claim 1, characterized in that, It also includes a funnel, which has an inlet and an outlet at its two ends, respectively, and the outlet is connected to the end of the connecting pipe away from the second guide component.

10. The liquid addition device according to claim 1, characterized in that, The first flow guiding component and the second flow guiding component are integrally formed structures; Alternatively, the first flow guiding component and the second flow guiding component may be connected by a snap-fit ​​or threaded connection.

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