Rotatable freezing tube rack for adipose-derived stem cells

Abstract

The utility model discloses a rotatable freezing tube rack for adipose-derived stem cells, which belongs to the technical field of stem cell research and comprises a base, a supporting rod is fixedly connected above the base, and a plurality of placing mechanisms are rotatably connected to the periphery of the supporting rod. After the placing mechanism is connected to the periphery of the supporting rod in a sleeving mode, the two L-shaped rods are moved oppositely, the L-shaped rods move to drive the limiting rods to move, the limiting rods move to extrude the reset springs, then the inserting rods are inserted into the inserting cavities, then the L-shaped rods are loosened, the reset springs lose the external force to drive the limiting rods to move and be inserted into the limiting grooves, and then the placing mechanism is placed. The inserting rod and the supporting rod can be inserted and fixed through the limiting rod, the fixed plug is limited and fixed to the end of the supporting rod under the connecting action of the ejector block, the fixed plug can be conveniently disassembled and assembled, and then workers can conveniently disassemble and assemble the placing mechanisms and the supporting rods of different numbers.

Description

Technical Field

[0001] This utility model belongs to the field of stem cell research technology, specifically relating to a rotatable cryopreservation rack for adipose stem cells. Background Technology

[0002] Adipose-derived stem cells (ADSCs) are a type of stem cell with multipotent differentiation potential isolated from adipose tissue in recent years. They primarily restore the repair function of tissue cells, promote cell regeneration, and restore a youthful appearance while significantly improving bodily functions. This effectively addresses sub-health conditions, premature aging, and other ailments, truly combating aging from the inside out.

[0003] Chinese Patent Application No. 202322151620.2 discloses a rotatable cryopreservation rack for adipose stem cells, including a base and a rotating ring. The base has a bottom rod, a support rod, and a fixing plug at the top of the support rod. The rotating ring has a fixed upper plate parallel to its top surface and a placement hole. A fixed lower plate, parallel to its bottom surface, is also provided. The rotating ring has a rotating rod, and a central axial hole allows it to be mounted on the support rod. This novel rotatable cryopreservation rack for adipose stem cells allows for convenient storage and retrieval.

[0004] In the aforementioned patent, a fixed plug is fixedly connected above the support rod. The fixed plug can easily affect the movement and connection of the rotating ring, making it difficult for the operator to adjust the number of rotating rings placed on the support rod as needed, thus affecting the overall performance of the device. In addition, the isolation column is used to separate two adjacent rotating rings, but the height of the isolation column is fixed, which results in a fixed distance between the two rotating rings, making it difficult to place cryopreservation tubes of different heights. Utility Model Content

[0005] To address the problems mentioned in the background section, this invention provides a rotatable cryopreservation holder for adipose-derived stem cells, which is easy to assemble, disassemble, and adjust.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a rotatable cryopreservation tube rack for adipose stem cells, including a base, a support rod fixedly connected above the base, a plurality of placement mechanisms rotatably connected around the support rod, a fixed plug provided at the end of the support rod away from the base, an adjustable isolation component provided between two adjacent placement mechanisms, and a plug-in component provided between the fixed plug and the support rod.

[0007] Preferably, the plug-in assembly includes a plug-in cavity, a return spring, a cavity, a plug-in rod, a limiting groove, a pushing component, a moving plate, and a limiting rod. The plug-in rod is provided at one end of the fixed plug near the support rod. A plug-in cavity is provided inside the support rod at the position corresponding to the plug-in rod. A cavity is provided inside the plug-in rod. Moving plates are slidably connected to both sides of the cavity. A return spring is fixedly connected between the two moving plates. A limiting rod is fixedly connected to the side of the two moving plates that are far apart from each other. A limiting groove is provided on the side wall of the plug-in cavity at the position corresponding to the limiting rod. A pushing component is provided on the side wall of the limiting rod.

[0008] Preferably, the pushing component includes an L-shaped rod, a top block, and a pushing groove. The top block is fixedly connected between the fixed plug and the plug rod. An L-shaped rod is fixedly connected to the side wall of the limiting rod. A pushing groove is provided on the side wall of the cavity at the position corresponding to the L-shaped rod.

[0009] Preferably, a limiting slider is fixedly connected to the side wall of the movable plate, and a limiting groove is formed on the inner side wall of the cavity at the position corresponding to the limiting slider.

[0010] Preferably, the adjustable isolation assembly includes a fixed cylinder, a lifting ring, a push rod, a top plate, a threaded column, a connecting spring, a threaded sleeve, and a side plate. The fixed cylinder is sleeved around the support rod and located between the two placement mechanisms. The side plate is fixedly connected to the side wall of the fixed cylinder. The threaded column is fixedly connected to the top of the side plate. The threaded sleeve is threadedly connected to the outer side wall of the threaded column. The push rod is slidably connected around the threaded sleeve and located above the threaded sleeve. The top plate is fixedly connected to the top of the threaded column. The connecting spring is fixedly connected between the top plate and the push rod and located around the threaded column. The lifting ring is fixedly connected to one end of the push rod.

[0011] Preferably, a guide post is fixedly connected to one end of the lifting ring near the fixed cylinder, and a guide hole is provided inside the fixed cylinder at the position corresponding to the guide post.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] 1. This utility model is equipped with a plug-in assembly. After the placement mechanism is sleeved onto the periphery of the support rod, two L-shaped rods move towards each other. The movement of the L-shaped rods drives the movement of the limiting rod. The movement of the limiting rod compresses the return spring, and then the plug-in rod is inserted into the plug-in cavity. Then the L-shaped rods are released, and the return spring loses its external force, causing the limiting rod to move and insert into the limiting groove. The limiting rod can be used to plug and fix the plug-in rod and the support rod. Under the connection of the top block, the fixing plug is fixed to the end of the support rod, which facilitates the disassembly and assembly of the fixing plug. This makes it easier for workers to disassemble and assemble different numbers of placement mechanisms and support rods.

[0014] 2. This utility model features an adjustable isolation assembly. After one placement mechanism is fitted onto the outer periphery of the support rod, a fixing sleeve is fitted onto the outer periphery of the support rod, positioning it above the placement mechanism. The lifting ring is then fitted onto the outer periphery of the support rod. The threaded sleeve is then rotated, causing it to move along the threaded post. The rotation of the threaded sleeve moves the pushing rod, which in turn moves the lifting ring and compresses the connecting spring. Once the lifting ring reaches the appropriate height, the rotation of the threaded sleeve is stopped. The other placement mechanism is then fitted onto the outer periphery of the support rod. When the placement mechanism is in contact with the side wall of the lifting ring, it stops moving due to obstruction. The remaining placement mechanisms are then fitted onto the outer periphery of the support rod in the same manner. This allows for adjustment of the distance between the two placement mechanisms, facilitating the storage of cryopreservation tubes of different heights using the placement mechanisms. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model;

[0016] Figure 2 This is a cross-sectional view of the present invention;

[0017] Figure 3 This is a cross-sectional view of the adjustable isolation component of this utility model;

[0018] Figure 4 This utility model Figure 3 Enlarged view of point A in the middle;

[0019] Figure 5 This is a partial sectional view showing the connection between the fixed plug and the support rod of this utility model.

[0020] In the diagram: 1. Fixed plug; 2. Placement mechanism; 3. Support rod; 4. Base; 5. Adjustable isolation assembly; 51. Fixed cylinder; 52. Lifting ring; 53. Push rod; 54. Top plate; 55. Threaded column; 56. Connecting spring; 57. Threaded sleeve; 58. Side plate; 6. Insertion assembly; 61. Insertion cavity; 62. Return spring; 63. Cavity; 64. Insertion rod; 65. Limiting groove; 66. Pushing component; 661. L-shaped rod; 662. Top block; 663. Pushing groove; 67. Moving plate; 68. Limiting rod. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Example 1

[0023] Please see Figure 1-5 The present invention provides the following technical solution: a rotatable cryopreservation tube rack for adipose stem cells, including a base 4, a support rod 3 fixedly connected above the base 4, a plurality of placement mechanisms 2 rotatably connected around the support rod 3, a fixed plug 1 provided at the end of the support rod 3 away from the base 4, an adjustable isolation component 5 provided between two adjacent placement mechanisms 2, and a plug-in component 6 provided between the fixed plug 1 and the support rod 3.

[0024] Specifically, the plug-in assembly 6 includes a plug-in cavity 61, a return spring 62, a cavity 63, a plug-in rod 64, a limiting groove 65, a pushing component 66, a moving plate 67, and a limiting rod 68. The fixed plug 1 has a plug-in rod 64 at one end near the support rod 3. A plug-in cavity 61 is formed inside the support rod 3 at the position corresponding to the plug-in rod 64. A cavity 63 is formed inside the plug-in rod 64. Moving plates 67 are slidably connected to both sides of the cavity 63. A return spring 62 is fixedly connected between the two moving plates 67. A limiting rod 68 is fixedly connected to the side of the two moving plates 67 that are far apart from each other. A limiting groove 65 is formed on the side wall of the plug-in cavity 61 at the position corresponding to the limiting rod 68. A pushing component 66 is provided on the side wall of the limiting rod 68.

[0025] By adopting the above technical solution, after the placement mechanism 2 is attached to the periphery of the support rod 3, the pushing component 66 drives the limiting rod 68 to move and retract into the cavity 63. The limiting rod 68 moves and squeezes the reset spring 62, and then the insertion rod 64 is inserted into the insertion cavity 61. Then the pushing component 66 is released, the reset spring 62 loses the external force and returns to its original state, driving the limiting rod 68 to move and insert into the limiting groove 65. The limiting rod 68 and the limiting groove 65 can be used to insert and fix the insertion rod 64 and the support rod 3, thereby limiting and fixing the fixing plug 1 to the end of the support rod 3, which facilitates the disassembly and assembly of the fixing plug 1, and thus facilitates the disassembly and assembly of the placement mechanism 2.

[0026] Specifically, the pushing component 66 includes an L-shaped rod 661, a top block 662, and a pushing groove 663. The top block 662 is fixedly connected between the fixed plug 1 and the plug rod 64. The L-shaped rod 661 is fixedly connected to the side wall of the limiting rod 68. The pushing groove 663 is provided on the side wall of the cavity 63 at the position corresponding to the L-shaped rod 661.

[0027] By adopting the above technical solution, two L-shaped rods 661 are moved in opposite directions, so that they move along the push groove 663. The movement of the L-shaped rods 661 drives the movement of the limiting rod 68, which facilitates the movement operation of the limiting rod 68. After the plug rod 64 is plugged and fixed inside the support rod 3, under the connection action of the top block 662, the fixing plug 1 is fixed to the end of the support rod 3, which facilitates the disassembly and assembly operation of the fixing plug 1.

[0028] Specifically, a limiting slider is fixedly connected to the side wall of the movable plate 67, and a limiting groove is formed on the inner side wall of the cavity 63 at the position corresponding to the limiting slider.

[0029] By adopting the above technical solution, the moving plate 67 moves and drives the limiting slider to move inside the limiting groove. With the cooperation of the limiting slider and the limiting groove, the moving plate 67 can be guided. When the limiting slider moves and fits against the side wall of the limiting groove, the limiting slider is blocked and stops moving, thereby preventing the moving plate 67 from moving out of the cavity 63.

[0030] In this embodiment, the appropriate placement mechanism 2 is fitted onto the periphery of the support rod 3 according to the amount of cryopreservation tubes containing stored adipose stem cells. Then, the two L-shaped rods 661 are moved towards each other, moving along the pushing groove 663. The movement of the L-shaped rods 661 causes the limiting rod 68 to move and retract into the cavity 63. The limiting rod 68 compresses the return spring 62, and then the insertion rod 64 is inserted into the insertion cavity 61. Then, the L-shaped rods 661 are released, the return spring 62 returns to its original position after losing external force, and the limiting rod 68 moves and inserts into the limiting groove 65. The limiting rod 68 and the limiting groove 65 can be used to insert and fix the insertion rod 64 and the support rod 3. Under the connection of the top block 662, the fixed plug 1 is fixed to the end of the support rod 3, which facilitates the installation and removal of the fixed plug 1. This makes it easier for staff to install and remove different numbers of placement mechanisms 2 and support rods 3. The adjustable isolation component 5 is used to isolate two adjacent placement mechanisms 2. The cryopreservation tube is then inserted into the placement mechanism 2. When different cryopreservation tubes need to be retrieved, the placement mechanism 2 at the corresponding position is rotated around the support rod 3, so that the placement mechanism 2 with the cryopreservation tube to be retrieved rotates away from other placement mechanisms 2. The placement mechanism 2 drives the cryopreservation tube to rotate, making it easier for staff to retrieve the required cryopreservation tube.

[0031] Example 2

[0032] The difference between this embodiment and Embodiment 1 is that the adjustable isolation assembly 5 includes a fixed cylinder 51, a lifting ring 52, a pushing rod 53, a top plate 54, a threaded column 55, a connecting spring 56, a threaded sleeve 57, and a side plate 58. A fixed cylinder 51 is sleeved around the support rod 3 and located between the two placement mechanisms 2. A side plate 58 is fixedly connected to the side wall of the fixed cylinder 51. A threaded column 55 is fixedly connected above the side plate 58. A threaded sleeve 57 is threadedly connected to the outer side wall of the threaded column 55. A pushing rod 53 is slidably connected around and above the threaded sleeve 57. A top plate 54 is fixedly connected above the threaded column 55. A connecting spring 56 is fixedly connected between the top plate 54 and the pushing rod 53 and around the threaded column 55. A lifting ring 52 is fixedly connected to one end of the pushing rod 53.

[0033] Specifically, a guide post is fixedly connected to one end of the lifting ring 52 near the fixed cylinder 51, and a guide hole is provided inside the fixed cylinder 51 at the position corresponding to the guide post.

[0034] By adopting the above technical solution, the lifting ring 52 moves, driving the guide column to move inside the guide hole. With the cooperation of the guide column and the guide hole, the movement of the lifting ring 52 can be guided, improving the stability of the movement of the lifting ring 52.

[0035] In this embodiment, one of the placement mechanisms 2 is fitted onto the outer periphery of the support rod 3, and then the fixing cylinder 51 is fitted onto the outer periphery of the support rod 3, positioning it above the placement mechanism 2. The lifting ring 52 is then fitted onto the outer periphery of the support rod 3. The threaded sleeve 57 is then rotated, causing it to rotate and move along the threaded post 55. The rotation and movement of the threaded sleeve 57 pushes the push rod 53, which in turn moves the lifting ring 52 and compresses the connecting spring 56. When the lifting ring 52 moves to a suitable height, the rotation of the threaded sleeve 57 is stopped. Then, the other placement mechanism 2 is fitted onto the outer periphery of the support rod 3. When the placement mechanism 2 is in contact with the side wall of the lifting ring 52, the placement mechanism 2 is obstructed and stops moving. The remaining placement mechanisms 2 are then fitted onto the outer periphery of the support rod 3 in the same way, making it easier to adjust the distance between the two placement mechanisms 2, thus facilitating the storage of cryopreservation tubes of different heights using the placement mechanisms 2.

[0036] The structure and principle of the placement mechanism 2, which consists of a rotating ring, a fixed upper plate, placement holes, a fixed lower plate, a rotating rod, and a shaft hole, have been disclosed in Chinese Patent Application No. 202322151620.2, which describes a rotatable cryopreservation tube rack for adipose stem cells. Its working principle is as follows: a rotating ring is sleeved around the support rod 3; the rotating ring is equipped with a fixed upper plate flush with its top surface; the fixed upper plate is a fan-shaped long plate with several placement holes; and the rotating ring is equipped with a fixed lower plate flush with its bottom surface. The positions of the rotating ring, the fixed upper plate, and the fixed lower plate are opposite. A rotating rod is provided in the direction of the rotating ring. The central shaft of the rotating ring is missing, and the missing part is set as a shaft hole. The support rod 3 passes through the shaft hole and is rotatably connected to the rotating ring. In use, the cryopreservation tube is passed through the tube placement hole on the fixed upper plate and placed on the fixed lower plate. Under the action of the fixed upper plate, the tube placement hole and the fixed lower plate, the cryopreservation tube can be stored and placed. The rotating ring is rotated by rotating the rotating rod, which drives the fixed upper plate to rotate. The fixed upper plate is rotated to a suitable position so that it rotates away from other fixed upper plates. Then the cryopreservation tube is taken out from the tube placement hole, which is convenient for the staff to operate.

[0037] The working principle and usage process of this utility model are as follows: One placement mechanism 2 is fitted onto the outer periphery of the support rod 3. Then, a fixing cylinder 51 is fitted onto the outer periphery of the support rod 3, positioned above the placement mechanism 2. The lifting ring 52 is then fitted onto the outer periphery of the support rod 3. The threaded sleeve 57 is rotated, causing it to rotate along the threaded post 55. The rotation of the threaded sleeve 57 pushes the moving rod 53, which in turn moves the lifting ring 52 and compresses the connecting spring 56. When the lifting ring 52 reaches a suitable height, the rotation of the threaded sleeve 57 is stopped. The other placement mechanism 2 is then fitted onto the outer periphery of the support rod 3. When the placement mechanism 2 is in contact with the side wall of the lifting ring 52, it stops moving. The remaining placement mechanisms 2 are then fitted onto the outer periphery of the support rod 3 in the same manner. This allows for adjustment of the distance between the two placement mechanisms 2, facilitating the storage of cryopreservation tubes at different heights using the placement mechanisms 2. Based on the amount of cryopreservation tubes for storing adipose stem cells, an appropriate number of placement mechanisms 2 are fitted onto the outer periphery of the support rod 3, and then the two mechanisms are moved towards each other. An L-shaped rod 661 is moved along the push groove 663. The movement of the L-shaped rod 661 causes the limiting rod 68 to move and retract into the cavity 63. The moving limiting rod 68 compresses the return spring 62, and then the insertion rod 64 is inserted into the insertion cavity 61. Then the L-shaped rod 661 is released, the return spring 62 loses its external force and returns to its original shape, causing the limiting rod 68 to move and insert into the limiting groove 65. The limiting rod 68 and the limiting groove 65 can be used to insert and fix the insertion rod 64 and the support rod 3, which is connected by the top block 662. The fixed plug 1 is then fixed to the end of the support rod 3, which facilitates the installation and removal of the fixed plug 1. This also makes it easier for staff to install and remove different numbers of placement mechanisms 2 and support rods 3. The cryopreservation tubes are then inserted into the placement mechanism 2. When different cryopreservation tubes need to be retrieved, the placement mechanism 2 at the corresponding position is rotated around the support rod 3. This causes the placement mechanism 2 containing the cryopreservation tube to rotate away from other placement mechanisms 2. The placement mechanism 2 drives the cryopreservation tube to rotate, making it easier for staff to retrieve the required cryopreservation tube.

[0038] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A rotatable cryopreservation tube rack for adipose stem cells, comprising a base (4), a support rod (3) fixedly connected above the base (4), a plurality of placement mechanisms (2) rotatably connected to the periphery of the support rod (3), and a fixing plug (1) provided at the end of the support rod (3) away from the base (4), characterized in that: An adjustable isolation component (5) is provided between two adjacent placement mechanisms (2), and a plug-in component (6) is provided between the fixed plug (1) and the support rod (3).

2. The rotatable cryopreservation holder for adipose-derived stem cells according to claim 1, characterized in that: The plug assembly (6) includes a plug cavity (61), a reset spring (62), a cavity (63), a plug rod (64), a limiting groove (65), a pusher (66), a moving plate (67), and a limiting rod (68). The fixed plug (1) is provided with a plug rod (64) at one end near the support rod (3). The support rod (3) has a plug cavity (61) at the position corresponding to the plug rod (64). The plug rod (64) has a cavity (63) at the inside. The moving plate (67) is slidably connected to both sides of the cavity (63). The reset spring (62) is fixedly connected between the two moving plates (67). The two moving plates (67) are fixedly connected to the side away from each other. The side of the two moving plates (67) is fixedly connected to the limiting rod (68). The side wall of the plug cavity (61) is provided with a limiting groove (65) at the position corresponding to the limiting rod (68). The pushing member (66) is provided on the side wall of the limiting rod (68).

3. The rotatable cryopreservation holder for adipose-derived stem cells according to claim 2, characterized in that: The pushing component (66) includes an L-shaped rod (661), a top block (662), and a pushing groove (663). The top block (662) is fixedly connected between the fixed plug (1) and the plug rod (64). The L-shaped rod (661) is fixedly connected to the side wall of the limiting rod (68). The pushing groove (663) is provided on the side wall of the cavity (63) at the position corresponding to the L-shaped rod (661).

4. The rotatable cryopreservation holder for adipose-derived stem cells according to claim 2, characterized in that: A limiting slider is fixedly connected to the side wall of the movable plate (67), and a limiting groove is opened on the inner side wall of the cavity (63) at the position corresponding to the limiting slider.

5. The rotatable cryopreservation holder for adipose-derived stem cells according to claim 1, characterized in that: The adjustable isolation assembly (5) includes a fixed cylinder (51), a lifting ring (52), a push rod (53), a top plate (54), a threaded column (55), a connecting spring (56), a threaded sleeve (57), and a side plate (58). The fixed cylinder (51) is sleeved around the support rod (3) and between the two placement mechanisms (2). The side plate (58) is fixedly connected to the side wall of the fixed cylinder (51). The threaded column (55) is fixedly connected above the side plate (58). The threaded sleeve (57) is threadedly connected to the outer side wall of the threaded column (55). The push rod (53) is slidably connected around the threaded sleeve (57) and above the threaded sleeve (57). The top plate (54) is fixedly connected above the threaded column (55). The connecting spring (56) is fixedly connected between the top plate (54) and the push rod (53) and around the threaded column (55). The lifting ring (52) is fixedly connected to one end of the push rod (53).

6. The rotatable cryopreservation holder for adipose-derived stem cells according to claim 5, characterized in that: The lifting ring (52) is fixedly connected to a guide post at one end near the fixed cylinder (51), and a guide hole is provided inside the fixed cylinder (51) at the position corresponding to the guide post.

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