Device for monitoring and evaluating effect of drug combination on microorganisms in dairy products

Abstract

The utility model provides a device for monitoring and evaluating the microbial effect of drug combination on dairy products, and relates to the technical field of microbial analysis. The main body of the device for monitoring and evaluating the microbial effect of the drug combination on the dairy product is a microbial effect migration disc. The microbial effect migration disc comprises a round disc body formed by a bottom plate and side plates. The separation ring table is arranged on the bottom plate in a protruding mode so as to divide the inner space of the tray body into an inner ring space and an outer ring space. The inner ring space is mainly used for inoculating primary microorganisms; the outer ring space is provided with a plurality of partition plates, and the partition plates are arranged in the outer ring space in the circumferential direction of the outer ring space at intervals so as to divide the outer ring space into a plurality of independent isolation spaces. The utility model aims at synchronously and in-situ testing the microbial effect in the dairy product by using different combinations, different proportions and different doses of drug combination in the same microbial effect migration plate, so that high-throughput, visual and in-situ control is realized, and errors caused by inconsistency of microbial flora sources are effectively avoided.

Description

Technical Field

[0001] This utility model relates to the field of microbial analysis technology, and more specifically, to a device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products. Background Technology

[0002] Dairy products, as special foods highly susceptible to microbial growth, have their safety and quality stability directly linked to public health and industrial development. The inhibitory or proliferative effects of drugs on microorganisms are a core concern in risk control. Combination therapy, through complex interaction mechanisms (such as synergistic, antagonistic, or additive effects), can delay or reduce microbial risks. However, the effects of combination therapy are influenced by various factors, including drug ratios and dosages, combination methods, and the heterogeneity of grandparent and different generations of microbial strains. The dynamic and uncertain nature of these factors makes exploring the characteristics of microbial quorum effects and screening control methods extremely complex.

[0003] In existing technologies, studies on the combined drug effects on dairy microorganisms typically employ a single-variable experimental model, where different dosage ratios or drug combinations are tested independently, and the results are then integrated and analyzed. However, this method has significant limitations: on the one hand, a large number of independent experiments significantly increases the workload; on the other hand, it is difficult to maintain complete consistency in experimental environments (such as temperature and humidity, culture medium batches, initial microbial concentrations, etc.), which may introduce systematic errors and affect the comparability of data and the reliability of conclusions.

[0004] Therefore, how to achieve high-throughput synchronous experiments and real-time observation comparisons of multiple variables (such as different drug ratios and combinations) has become a technical bottleneck that urgently needs to be overcome in this field. Utility Model Content

[0005] The purpose of this invention is to provide a device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products. This device can simultaneously conduct tests on the effects of different ratios, dosages, and combinations of drugs on microorganisms in dairy products in a microbial effect transfer plate, thereby reducing the amount of testing and facilitating mutual comparison, while also avoiding the problem of systematic errors.

[0006] The embodiments of this utility model can be implemented as follows:

[0007] This invention provides a device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products, including a microbial effect migration disk;

[0008] Microbial effect migration disks include:

[0009] A circular disc formed by a base plate and side plates;

[0010] A dividing ring platform protrudes from the base plate to divide the internal space of the disc into an inner ring space and an outer ring space.

[0011] Multiple partitions are arranged at circumferential intervals in the outer ring space to divide the outer ring space into multiple independent isolated spaces.

[0012] In an optional embodiment, the partition ring stage includes a first partition ring stage and a second partition ring stage;

[0013] The first and second partition rings are both concentrically protruding from the base plate, and the diameter of the second partition ring is larger than the diameter of the first partition ring.

[0014] The first dividing ring platform encloses and forms an inner ring space;

[0015] The first and second dividing ring platforms enclose an outer ring space;

[0016] The microbial effect migration tray also includes a water tank, which is ring-shaped and located between the second partition ring platform and the side plate.

[0017] In an optional implementation, the partition ring platform further includes a third partition ring platform;

[0018] The third dividing ring platform is disposed between the first dividing ring platform and the second dividing ring platform to divide the outer ring space into a first outer ring space located between the first dividing ring platform and the third dividing ring platform and a second outer ring space located between the third dividing ring platform and the second dividing ring platform.

[0019] Both the first outer ring space and the second outer ring space are equipped with partition plates spaced circumferentially.

[0020] In an optional implementation, the first and third partition rings have the same height.

[0021] The height of the second partition ring is greater than the height of the first and third partition rings;

[0022] The height of the partition plate is greater than the height of the first and third partition rings, but less than the height of the second partition ring.

[0023] In an optional implementation, the partition plate includes a first partition plate and a second partition plate;

[0024] The first partition plate includes at least two, the first partition plate protrudes from the bottom plate, and one end is connected to the first partition ring platform, and the other end is connected to the second partition ring platform, so as to divide the first outer ring space and the second outer ring space in the circumferential direction;

[0025] There are multiple second partition plates. The second partition plate protrudes from the bottom plate and is connected at one end to the second partition ring platform and at the other end to the third partition ring platform, so as to divide the second outer ring space in the circumferential direction.

[0026] In an optional implementation, there are two first partitions, and the central angle between the two first partitions is 180°.

[0027] In an optional implementation, there are six second partitions, and the six second partitions and two first partitions can divide the second outer ring space into eight isolation spaces.

[0028] In an alternative embodiment, the partition plate is arranged radially along the disc body.

[0029] In an optional implementation, the base plate is made of a black, opaque material;

[0030] The microbial effect migration tray also includes a cover plate;

[0031] The side panels, partition rings, and cover are all made of transparent material, and the side panels are equipped with scales.

[0032] In an optional implementation, the device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products further includes a reaction chamber, an imaging device, a chamber water tank, a heating component, a lifting and rotating tray, an environmental monitoring device, and a carbon dioxide cylinder.

[0033] The reaction chamber has a reaction cavity;

[0034] The imaging device is located at the top of the reaction chamber and can be connected to a computer to transmit images;

[0035] The lifting and rotating tray is located at the bottom of the reaction chamber and is positioned corresponding to the imaging device;

[0036] The environmental monitoring device is installed inside the reaction chamber;

[0037] A carbon dioxide cylinder is connected to the reaction chamber to supply carbon dioxide to the reaction chamber;

[0038] The water tank is located on top of the lifting and rotating tray, and the heating element is located in the water tank.

[0039] The microbial effect migration tray is placed inside the tank.

[0040] The beneficial effects of the device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products provided in this embodiment of the invention include:

[0041] The device provided in this application for monitoring and evaluating the effects of combined drug use on the microorganisms in dairy products includes a microbial effect migration disk. The microbial effect migration disk comprises a circular disk body formed by a base plate and side plates. A partition ring protrudes from the base plate, dividing the internal space of the disk body into an inner ring space and an outer ring space. Multiple partition plates are spaced circumferentially along the outer ring space, dividing the outer ring space into multiple independent isolation spaces. A water tank is annular and located at the outer periphery of the outer ring space. This allows for the monitoring and evaluation of the effects of combined drug use on the microorganisms in dairy products by placing the microorganisms in the inner ring space, while simultaneously conducting experiments with different drug ratios and combinations in different isolation spaces of the outer ring space. This achieves high throughput, visualization, in-situ control, and effectively avoids errors caused by inconsistencies in the source of the microbial community, greatly improving the effectiveness and accuracy of the experiment. Attached Figure Description

[0042] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0043] Figure 1 A schematic diagram of the microbial effect migration disk of the device for monitoring and evaluating the microbial effects of combined drug use on dairy products provided in this embodiment;

[0044] Figure 2 An exploded view of the microbial effect migration disk of the device for monitoring and evaluating the microbial effects of combined drug use on dairy products provided in this embodiment;

[0045] Figure 3 A top view schematic diagram of the microbial effect migration disk of the device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products provided in this embodiment;

[0046] Figure 4 A cross-sectional schematic diagram of the microbial effect migration disk of the device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products provided in this embodiment;

[0047] Figure 5 This is a schematic diagram of the device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products, provided in this embodiment.

[0048] Icons: 100 - Device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products; 110 - Microbial effect migration plate; 111 - Base plate; 112 - Side plate; 113 - Plate body; 114 - Separating ring platform; 115 - Separating plate; 116 - Inner ring space; 117 - Outer ring space; 118 - Isolation space; 119 - First separating ring platform; 120 - Second separating ring platform; 121 - Water tank; 122 - Third separating ring platform; 123 - First outer ring space; 124 - Second outer ring space; 125 - First separating plate; 126 - Second separating plate; 127 - Cover plate; 130 - Reaction chamber; 131 - Reaction cavity; 140 - Imaging device; 150 - Box body water tank; 160 - Heating component; 170 - Lifting and rotating tray; 180 - Environmental monitoring device; 190 - Carbon dioxide cylinder. Detailed Implementation

[0049] In existing technologies, studies on the combined drug effects on dairy microorganisms typically employ a single-variable experimental model, where different dosage ratios or drug combinations are tested independently, and the results are then integrated and analyzed. However, this method has significant limitations: on the one hand, a large number of independent experiments significantly increases the workload; on the other hand, it is difficult to maintain complete consistency in experimental environments (such as temperature and humidity, culture medium batches, initial microbial concentrations, etc.), which may introduce systematic errors and affect the comparability of data and the reliability of conclusions.

[0050] Therefore, how to achieve high-throughput synchronous experiments and real-time observation comparisons of multiple variables (such as different drug ratios and combinations) has become a technical bottleneck that urgently needs to be overcome in this field.

[0051] To address the aforementioned problems, this invention provides a device for monitoring and evaluating the effects of combined drug use on the microorganisms in dairy products. This device can simultaneously conduct experiments on the effects of different ratios, dosages, and combinations of combined drugs on the microorganisms in dairy products within a single microbial effect transfer disc. This achieves high throughput, visualization, in-situ control, and effectively avoids errors caused by inconsistencies in the source of the microbial community, greatly improving the effectiveness and accuracy of the experiment. To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions in the embodiments of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. The components of the embodiments of this invention described and shown in the accompanying drawings can be arranged and designed in various different configurations.

[0052] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0053] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0054] In the description of this utility model, it should be noted that if terms such as "upper," "lower," "inner," or "outer" are used to indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship in which the utility model product is usually placed during use, they are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0055] Furthermore, the terms "first" and "second" are used only to distinguish descriptions and should not be interpreted as indicating or implying relative importance.

[0056] It should be noted that, where there is no conflict, the features in the embodiments of this utility model can be combined with each other.

[0057] The following detailed description, through embodiments and in conjunction with the accompanying drawings, details the overall structure, working principle, and technical effects of a device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products provided by this utility model.

[0058] Please refer to Figure 1 and Figure 2 This invention provides a device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products. This device can simultaneously conduct tests on the effects of combined drug use with different ratios, dosages, and combinations on microorganisms in dairy products. This reduces the amount of testing required, facilitates cross-comparison, and avoids systematic errors.

[0059] Please refer to Figures 1 to 4In this embodiment, the device 100 for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products includes a microbial effect migration disk 110. The microbial effect migration disk 110 includes a circular disk body 113 formed by a base plate 111 and side plates 112, a partition ring platform 114, and multiple partition plates 115. The partition ring platform 114 protrudes from the base plate 111 to divide the internal space of the disk body 113 into an inner ring space 116 and an outer ring space 117. The multiple partition plates 115 are spaced apart circumferentially along the outer ring space 117 to divide the outer ring space 117 into multiple independent isolation spaces 118.

[0060] The device 100 for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products provided in this embodiment includes a microbial effect migration disk 110. The microbial effect migration disk 110 includes a circular disk 113 formed by a base plate 111 and side plates 112. A dividing ring platform 114 protrudes from the base plate 111, dividing the internal space of the disk 113 into an inner ring space 116 and an outer ring space 117. Multiple dividing plates 115 are spaced circumferentially along the outer ring space 117, dividing the outer ring space 117 into multiple independent isolation spaces 118. A water tank 121 is annular and disposed at the outer periphery of the outer ring space 117. In this way, when monitoring and evaluating the effects of combined drug use on the microbial effects in dairy products, the microorganisms can be placed in the inner ring space 116, while drugs with different drug ratios and combinations can be placed in different isolated spaces 118 in the outer ring space 117 for simultaneous testing. This achieves high throughput, visualization, in-situ control, and effectively avoids errors caused by inconsistencies in the source of the microbial community, greatly improving the effectiveness and accuracy of the experiment.

[0061] For example, when constructing the experimental system, nutrient agar medium can be inoculated in the inner ring space 116, while different mixtures and concentration ratios of drug solutions and nutrient agar medium are inoculated in all the isolation spaces 118 of the outer ring space 117 according to the experimental design. After the nutrient agar medium solidifies, bacterial solution and soft agar medium are again inoculated in the inner ring space 116, and soft agar medium is inoculated in the isolation spaces 118 of the outer ring space 117, thus completing the system construction and incubation. During the incubation process, microorganisms in the bacterial solution can migrate to the isolation spaces 118 of the outer ring space 117 via the soft agar medium.

[0062] Please refer to Figures 1 to 4In this embodiment, the partition ring platform 114 includes a first partition ring platform 119 and a second partition ring platform 120. Both the first partition ring platform 119 and the second partition ring platform 120 are concentrically protruding from the base plate 111, and the diameter of the second partition ring platform 120 is larger than the diameter of the first partition ring platform 119. The first partition ring platform 119 encloses an inner ring space 116. The first partition ring platform 119 and the second partition ring platform 120 enclose an outer ring space 117. The microbial effect migration plate 110 also includes a water tank 121, which is annular and disposed between the second partition ring platform 120 and the side plate 112.

[0063] In this embodiment, a water tank 121 is provided on the outer periphery of the outer ring space 117. During the experiment, sterile pure water is added to the water tank 121 to prevent the edge effect from causing the culture medium to dry out over a long period of time, and to improve the problem of external bacteria entering the isolation space 118.

[0064] In this embodiment, the partition ring platform 114 further includes a third partition ring platform 122. The third partition ring platform 122 is disposed between the first partition ring platform 119 and the second partition ring platform 120 to divide the outer ring space 117 into a first outer ring space 123 located between the first partition ring platform 119 and the third partition ring platform 122 and a second outer ring space 124 located between the third partition ring platform 122 and the second partition ring platform 120. Partition plates 115 are provided circumferentially spaced within both the first outer ring space 123 and the second outer ring space 124.

[0065] In this embodiment, a third separating ring platform 122 is provided, so that the outer ring space 117 can be set as a first outer ring space 123 located on the inside and a second outer ring space 124 located on the outside. Microorganisms need to pass through the isolation space 118 of the first outer ring space 123 before entering the isolation space 118 of the second outer ring space 124. This allows for more complex tests on the effects of combined drugs on microorganisms in dairy products, and also simplifies the operation of tests on the effects of complex combined drugs on microorganisms in dairy products.

[0066] Please refer to Figures 1 to 4 In this embodiment, the first dividing ring platform 119 and the third dividing ring platform 122 have the same height. The second dividing ring platform 120 has a height greater than the heights of the first dividing ring platform 119 and the third dividing ring platform 122. The dividing plate 115 has a height greater than the heights of the first dividing ring platform 119 and the third dividing ring platform 122, but less than the height of the second dividing ring platform 120.

[0067] The heights of the first separating ring platform 119, the second separating ring platform 120, and the third separating ring platform 122, as well as the height of the separating plate 115, are set in the above manner to facilitate the inoculation of culture medium and to facilitate isolation and migration of microorganisms.

[0068] In this embodiment, the height of the first dividing ring platform 119 is 1.5 cm, and the height of the third dividing ring platform 122 is also 1.5 mm. The height of the third dividing ring platform 122 is also 4 mm. The height of the dividing plate 115 is 3 cm.

[0069] For example, when constructing the experimental system, 1.5 g / L nutrient agar medium can be inoculated in the inner ring space 116 to a height of 1.5 cm, level with the first outer ring. In all the isolation spaces 118 of the outer ring space 117, different mixing ratios and concentrations of the drug solution and 1.5 g / L nutrient agar medium are inoculated according to the experimental design to a height of 1.5 cm, level with the first separating ring platform 119 and the third outer ring. After the nutrient agar medium solidifies, bacterial solution and 0.3% soft agar medium are again inoculated in the inner ring space 116 to a height of 3 cm, level with the partition. Meanwhile, 0.3% soft agar medium is inoculated in the isolation spaces 118 of the outer ring space 117 to a height of 3 cm, level with the partition. This completes the system construction and allows for cultivation. During cultivation, microorganisms in the bacterial solution can migrate from the soft agar medium to the outer periphery into the isolation spaces 118 of the ring space.

[0070] Please refer to Figures 1 to 4 In this embodiment, the partition plate 115 includes a first partition plate 125 and a second partition plate 126. There are at least two first partition plates 125, each protruding from the base plate 111 and connected at one end to a first partition ring platform 119 and at the other end to a second partition ring platform 120, thereby dividing the first outer ring space 123 and the second outer ring space 124 circumferentially. There are multiple second partition plates 126, each protruding from the base plate 111 and connected at one end to a second partition ring platform 120 and at the other end to a third partition ring platform 122, thereby dividing the second outer ring space 124 circumferentially and dividing the second outer ring space 124 separated by two adjacent first partition plates 125 into smaller spaces.

[0071] In this embodiment, through the above-described structure, one partition space of the first outer ring space 123 can correspond to several partition spaces of the second outer ring space 124, which facilitates the conduct of control experiments and makes the setup of the experiment more convenient.

[0072] In this embodiment, there are two first partition plates 125, and the central angle between the two first partition plates 125 is 180°. There are six second partition plates 126, and the six second partition plates 126 and the two first partition plates 125 can divide the second outer ring space 124 into eight isolation spaces 118.

[0073] The above structure can divide the first inner ring space 116 into two isolation spaces 118, and the second outer ring space 124 into eight outer ring spaces 117. The isolation spaces 118 of the first inner ring will correspond to the four isolation spaces 118 of the second outer ring space 124, so that multiple sets of control experiments can be carried out to analyze the migration of microorganisms.

[0074] Of course, in some embodiments of this application, three first partition plates 125 may be set, such that the included angle between any two adjacent plates is 120°. The number of corresponding second partition plates can be set according to experimental requirements. For example, one, two, three, or more second partition plates may be evenly arranged in the second outer ring space 124 separated by any two adjacent first partition plates. This allows for more in-situ, synchronous migration experiments of different types. The number of first partition plates may also be four or even more, and the number of first and second partition plates may be set according to the requirements of the experimental control examples.

[0075] Secondly, it should be noted that this embodiment is described by dividing the external space into a first outer ring space 123 and a second outer ring. The outer ring space 117 can also be divided into more radially distributed concentric circles as needed.

[0076] Please refer to Figures 1 to 4 In this embodiment, the partition plate 115 is arranged radially along the disk body 113. Distributing the partition plate 115 radially along the disk body 113 facilitates the formation of migration paths of the same length.

[0077] In this embodiment, the base plate 111 is made of a black, opaque material. This embodiment uses a black, opaque material for the base plate 111 to reduce background noise during image acquisition.

[0078] Of course, in some other embodiments of this application, the base plate 111 may also be made of a transparent material. When the base plate 111 is made of a transparent material, sterile ink (preferably black) that is harmless to the growth of microorganisms and has no interaction with drugs can be added to the culture medium to reduce background noise.

[0079] Please refer to Figures 1 to 4 In this embodiment, the microbial effect migration disk 110 also includes a cover plate 127. The cover plate 127 can be placed on top of the disk body 113 to isolate the influence of the external environment on the experiment. The cover plate 127 is made of transparent material to facilitate external observation and acquisition of process images. In order to acquire better images, the thickness of the cover plate 127 should be set as thin as possible and the transparency should be as high as possible.

[0080] In this embodiment, the side plate 112, the partition ring platform 114, and the partition plate 115 are also made of transparent material, and the side plate 112 is provided with a scale. Making the side plate 112, the partition ring platform 114, and the partition plate 115 also made of transparent material and providing a scale facilitates observation of the added culture medium height from the outside.

[0081] Please refer to Figures 1 to 5 In this embodiment, the device 100 for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products further includes a reaction chamber 130, an imaging device 140, a tank 150, a heating assembly 160, a lifting and rotating tray 170, an environmental monitoring device 180, and a carbon dioxide cylinder 190. The reaction chamber 130 has a reaction cavity 131. The imaging device 140 is located at the top of the reaction cavity 131 and can be connected to a computer to transmit images. The lifting and rotating tray 170 is located at the bottom of the reaction cavity 131 and is positioned corresponding to the imaging device 140. The environmental monitoring device 180 is located inside the reaction cavity 131. The carbon dioxide cylinder 190 is connected to the reaction chamber 130 to supply carbon dioxide gas to the reaction cavity 131. The tank 150 is located at the top of the lifting and rotating tray 170. The heating assembly 160 is located in the tank 150. The microbial effect transfer tray 110 is located inside the tank 150.

[0082] In this embodiment, the reaction chamber 130 helps maintain stable experimental environmental conditions. A water bath 150 within the chamber, equipped with a heating element 160, better heats the microbial effect migration tray 110, ensuring its temperature remains optimal for microbial growth. An environmental monitoring device 180 detects environmental parameters within the reaction chamber 131, such as temperature, humidity, and carbon dioxide concentration. This device may be a module of integrated sensors. A lifting and rotating tray 170 adjusts the height and position of the microbial effect migration tray 110, allowing the imaging device 140 to capture images of the tray. A carbon dioxide cylinder 190 supplies carbon dioxide to the reaction chamber 131.

[0083] In some embodiments of this application, the imaging device 140 may be a high-resolution imager or a laser scanner, which can be connected to a computer to acquire information and data on the migration and evolution trajectory of microorganisms during the experiment.

[0084] In summary, the device 100 for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products provided in this embodiment includes a microbial effect migration disk 110. The microbial effect migration disk 110 includes a circular disk 113 formed by a base plate 111 and side plates 112. A dividing ring platform 114 protrudes from the base plate 111, dividing the internal space of the disk 113 into an inner ring space 116 and an outer ring space 117. Multiple dividing plates 115 are spaced circumferentially along the outer ring space 117, dividing the outer ring space 117 into multiple independent isolation spaces 118. A water tank 121 is annular and disposed at the outer periphery of the outer ring space 117. In this way, when monitoring and evaluating the effects of combined drug use on the microbial effects in dairy products, the microorganisms can be placed in the inner ring space 116, while drugs with different drug ratios and combinations can be placed in different isolated spaces 118 in the outer ring space 117 for simultaneous testing. This achieves high throughput, visualization, in-situ control, and effectively avoids errors caused by inconsistencies in the source of the microbial community, greatly improving the effectiveness and accuracy of the experiment.

[0085] The above description is only a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model.

Claims

1. A device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products, characterized in that, Including microbial effect migration disk (110); The microbial effect migration disk (110) includes: A circular disc (113) formed by a base plate (111) and a side plate (112); A dividing ring platform (114) protrudes from the base plate (111) to divide the internal space of the disc body (113) into an inner ring space (116) and an outer ring space (117); Multiple partitions (115) are arranged circumferentially in the outer ring space (117) to divide the outer ring space (117) into multiple independent isolation spaces (118).

2. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to claim 1, characterized in that, The partition ring platform (114) includes a first partition ring platform (119) and a second partition ring platform (120); The first dividing ring platform (119) and the second dividing ring platform (120) are both concentrically protruding from the bottom plate (111), and the diameter of the second dividing ring platform (120) is larger than the diameter of the first dividing ring platform (119); The first dividing ring platform (119) encloses and forms the inner ring space (116); The outer ring space (117) is formed by the first dividing ring platform (119) and the second dividing ring platform (120); The microbial effect migration plate (110) also includes a water tank (121), which is annular and disposed between the second partition ring platform (120) and the side plate (112).

3. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to claim 2, characterized in that, The partition ring platform (114) further includes a third partition ring platform (122); The third dividing ring platform (122) is disposed between the first dividing ring platform (119) and the second dividing ring platform (120) to divide the outer ring space (117) into a first outer ring space (123) located between the first dividing ring platform (119) and the third dividing ring platform (122) and a second outer ring space (124) located between the third dividing ring platform (122) and the second dividing ring platform (120); The partition plates (115) are arranged circumferentially in both the first outer ring space (123) and the second outer ring space (124).

4. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to claim 3, characterized in that, The first dividing ring platform (119) and the third dividing ring platform (122) have the same height; The height of the second dividing ring platform (120) is greater than the height of the first dividing ring platform (119) and the third dividing ring platform (122); The height of the partition plate (115) is greater than the height of the first partition ring platform (119) and the third partition ring platform (122), and less than the height of the second partition ring platform (120).

5. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to claim 3, characterized in that, The partition plate (115) includes a first partition plate (125) and a second partition plate (126); The first partition plate (125) includes at least two, the first partition plate (125) protrudes from the bottom plate (111), and one end is connected to the first partition ring platform (119), and the other end is connected to the second partition ring platform (120) to separate the first outer ring space (123) and the second outer ring space (124) in the circumferential direction; There are multiple second partition plates (126). The second partition plate (126) protrudes from the bottom plate (111) and one end is connected to the second partition ring platform (120), and the other end is connected to the third partition ring platform (122) to divide the second outer ring space (124) in the circumferential direction.

6. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to claim 5, characterized in that, There are two first partition plates (125), and the central angle between the two first partition plates (125) is 180°.

7. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to claim 6, characterized in that, There are six second partitions (126), and the six second partitions (126) and two first partitions (125) can divide the second outer ring space (124) into eight isolation spaces (118).

8. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to any one of claims 1-7, characterized in that, The partition plate (115) is arranged radially along the disc body (113).

9. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to any one of claims 1-7, characterized in that, The base plate (111) is made of black opaque material; The microbial effect migration disk (110) also includes a cover plate (127); The side plate (112), the partition ring platform (114), and the cover plate (127) are all made of transparent material, and the side plate (112) is provided with a scale.

10. The apparatus for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products according to any one of claims 1-7, characterized in that, The device for monitoring and evaluating the effects of combined drug use on microorganisms in dairy products also includes a reaction chamber (130), an imaging device (140), a tank (150), a heating assembly (160), a lifting and rotating tray (170), an environmental monitoring device (180), and a carbon dioxide cylinder (190). The reaction chamber (130) has a reaction cavity (131); The imaging device (140) is located on top of the reaction chamber (131) and can be connected to a computer to transmit images; The lifting and rotating tray (170) is located at the bottom of the reaction chamber (131) and is positioned corresponding to the imaging device (140); The environmental monitoring device (180) is installed inside the reaction chamber (131); The carbon dioxide cylinder (190) is connected to the reaction chamber (130) to supply carbon dioxide to the reaction chamber (131); The tank water tank (150) is disposed on the top of the lifting and rotating tray (170), and the heating component (160) is disposed on the tank water tank (150); The microbial effect migration plate (110) is disposed inside the tank (150).

Images