Suspension slurry preparation tank
By using an eccentric stirring paddle and lifting device in the mixing tank, combined with an inclined bottom and a flow guide groove, the problems of uneven mixing and bottom residue in traditional mixing tanks are solved, achieving more efficient drug solution preparation and quality assurance.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- TIPR PHARM CO LTD
- Filing Date
- 2025-04-02
- Publication Date
- 2026-05-15
AI Technical Summary
Traditional mixing tanks suffer from uneven mixing and the inability of the bottom suspension to fully enter the spraying pipeline, resulting in unstable drug quality.
The design employs an eccentric stirring paddle and lifting device, combined with an inclined bottom and a guide groove, to ensure uniform mixing and promote the flow of the bottom suspension into the spray pipe.
It improves the uniformity of stirring, reduces the risk of suspension sedimentation, reduces bottom residue, ensures the amount of drug solution added and product quality, and is easy to operate.
Smart Images
Figure CN224236577U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of slurry mixing tank technology, and in particular relates to a suspension slurry mixing tank. Background Technology
[0002] With the rapid development of the modern pharmaceutical industry and the ever-increasing demands for production efficiency, product quality, and environmental protection, fluidized bed one-step granulation technology, as a significant innovation in granulation processes, is gradually changing traditional drug production processes and bringing about a revolution in the pharmaceutical industry. Fluidized bed one-step granulation not only improves the efficiency of pharmaceutical production, reduces energy consumption, and eliminates dust pollution, but also better ensures the uniformity of drug content, providing a higher standard for product quality control.
[0003] To ensure the precise implementation of the one-step fluidized bed granulation process, the most critical step is the preparation of the spray solution. Preparing a single solution is relatively simple and places no special requirements on the overall mechanical properties of the mixing tank. However, preparing a homogeneous suspension of poorly soluble drugs, maintaining this suspension for an extended period without sedimentation during further granulation, and ensuring complete entry into the fluidized bed's spray pipeline places higher demands on the tank design, mechanical properties, and ease of operation of the mixing tank. Traditional mixing tanks suffer from the following problems:
[0004] 1. The agitator is designed with a central axis, which means that the liquid at the edge of the mixing tank cannot be stirred, thus failing to guarantee the uniformity of stirring and posing a risk of sedimentation for suspensions;
[0005] 2. The suspension at the bottom of the mixing tank cannot completely enter the spraying pipeline, resulting in 10% to 15% of the suspension remaining at the bottom of the mixing tank at the preparation endpoint, which cannot be fed into the solution. For solutions containing drugs, the reduced feeding amount will affect the quality of the drugs. Utility Model Content
[0006] To solve the above-mentioned technical problems, this utility model provides a suspension mixing tank, which effectively solves the technical problems that the mixing tank cannot guarantee uniform mixing and that the suspension at the bottom cannot completely enter the spraying pipeline, thus overcoming the shortcomings of the prior art.
[0007] The technical solution adopted in this utility model is: a suspension mixing tank, comprising:
[0008] The mixing tank is equipped with an eccentric stirring paddle inside, and a slurry outlet is provided on one side of the bottom of the mixing tank.
[0009] The base is located below the mixing tank, with one side rotatably connected to the side of the mixing tank where the slurry outlet is located, and the other side is equipped with a lifting device, which allows the mixing tank to tilt toward the side where the slurry outlet is located.
[0010] Furthermore, the top of the mixing tank is provided with a fixed top cover on one side and an openable top cover on the other side. The eccentric stirring paddle is mounted on the fixed top cover and is rotatably connected to the fixed top cover.
[0011] Furthermore, the fixed top cover is equipped with a drive motor, which is used to drive the eccentric stirring paddle to rotate. The drive motor is equipped with a digital display device to display the rotational speed of the eccentric stirring paddle.
[0012] Furthermore, a screen is provided at the top of the mixing tank corresponding to the position of the opening and closing top cover, and the screen is detachably connected to the top of the mixing tank.
[0013] Furthermore, a support is provided at the top of the mixing tank corresponding to the position of the opening and closing top cover, and the screen is mounted on the support and detachably connected to the support.
[0014] Furthermore, the bottom of the mixing tank is configured as an inclined surface, with the side of the inclined surface near the slurry outlet being lower than the side away from the slurry outlet.
[0015] Furthermore, a flow guiding groove is provided on the inclined surface facing the slurry outlet.
[0016] Furthermore, a first hinge seat is provided on the side of the mixing tank away from the slurry outlet, the first hinge seat is hinged to the movable end of the lifting device, and a second hinge seat is provided on the base, the second hinge seat is hinged to the fixed end of the lifting device.
[0017] Furthermore, the inner wall of the mixing tank is provided with graduation lines.
[0018] Furthermore, the base is equipped with casters at its bottom.
[0019] The advantages and positive effects of this invention are: it reduces the dead zone of stirring, improves the uniformity of stirring, reduces the risk of suspension sedimentation, ensures the stirring effect, further promotes the flow of the suspension at the bottom, significantly reduces the bottom residue of the suspension, ensures the amount of feed when preparing drug solutions, and reliably guarantees product quality. It also has a simple structure and is easy to operate. Attached Figure Description
[0020] The above and other objects, features, and advantages of this utility model will become more apparent from the more detailed description of the embodiments thereof in conjunction with the accompanying drawings. The drawings are provided to further illustrate the embodiments of this utility model and form part of the specification. They are used together with the embodiments of this utility model to explain the utility model and do not constitute a limitation thereof. In the drawings, the same reference numerals generally represent the same parts or steps.
[0021] Figure 1 This is a front view of a suspension mixing tank according to an embodiment of the present invention.
[0022] Figure 2 This is a top view of a suspension mixing tank according to an embodiment of the present invention.
[0023] Figure 3 This is a schematic diagram of an inclined suspension mixing tank according to an embodiment of the present invention.
[0024] In the picture:
[0025] 1. Mixing tank body; 2. Base; 3. Eccentric mixing impeller
[0026] 4. Slurry outlet 5. Slurry outlet valve 6. Lifting device
[0027] 7. Fix the top cover 8. Open and close the top cover 9. Stirring shaft
[0028] 10. Drive motor 11. Digital display device 12. Screen
[0029] 13. Bracket; 14. Flow guide groove; 15. First hinge seat
[0030] 16. Second hinge seat; 17. First connector; 18. Second connector
[0031] 19. Connecting block; 20. Casters; 21. Handle Detailed Implementation
[0032] This utility model provides a suspension mixing tank, and the embodiments of this utility model will be described below with reference to the accompanying drawings.
[0033] In the description of the embodiments of this utility model, it should be understood that the terms "top," "bottom," etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. In the description of this utility model, it should be noted that unless otherwise expressly specified and limited, the terms "set" and "connected" should be interpreted broadly. For example, it can refer to a fixed connection, a detachable connection, or an integral connection; it can refer to a direct connection or an indirect connection through an intermediate medium; it can refer to the internal communication of two elements. Those skilled in the art can understand the specific meaning of the above terms in this utility model through specific circumstances.
[0034] like Figure 1 , Figure 2 and Figure 3As shown in the figure, an embodiment of this utility model discloses a suspension mixing tank, including a mixing tank body 1 and a base 2. An eccentric stirring paddle 3 is installed inside the mixing tank body 1. The stirring shaft 9 of the eccentric stirring paddle 3 is offset from the central axis of the mixing tank body 1. Compared with traditional central stirring, eccentric stirring disrupts symmetry, generating stronger radial and axial flow, enhancing the relative movement of the suspension liquid layers, and reducing dead zones. Eccentric stirring can reduce eddy current interference, enhance shear force, make the suspension more uniform, prevent particle sedimentation in the suspension, and ensure stirring effect. A slurry outlet 4 is provided on one side of the bottom of the mixing tank body 1, which is connected to the spray pipe of the fluidized bed to transfer the suspension to the fluidized bed. A slurry outlet valve 5 is installed on the slurry outlet 4. The base 2 is located below the mixing tank body 1, with one side rotatably connected to the side of the mixing tank body 1 with the slurry outlet 4, and a lifting device 6 on the other side. The lifting device 6 lifts the slurry tank 1 away from the slurry outlet 4, causing the slurry tank 1 to rotate and tilt towards the side with the slurry outlet 4, so that the suspension at the bottom of the slurry tank 1 can more easily flow into the slurry outlet 4 and enter the fluidized bed spraying pipeline.
[0035] Specifically, such as Figure 2 As shown, the top of the mixing tank 1 is provided with a fixed top cover 7 on one side and an openable top cover 8 on the other side. Preferably, half of the top of the mixing tank 1 is covered by the fixed top cover 7 and the other half is covered by the openable top cover 8. The fixed top cover 7 is fixedly connected to the top of the mixing tank 1, and the openable top cover 8 is connected to the fixed top cover 7 by a hinge. The stirring shaft 9 of the eccentric stirring paddle 3 is vertically set and rotatably connected to the fixed top cover 7, so that the stirring shaft 9 of the eccentric stirring paddle 3 is offset from the central axis of the mixing tank 1. Usually, the suspension contains surfactants, which will generate a lot of foam during the stirring process. In order to avoid the foam in the suspension from affecting the liquid supply to the fluidized bed, during the preparation of the suspension, the suspension in the mixing tank 1 needs to flow into the external material tank through the slurry outlet 4 to remove the foam, and then the openable top cover 8 is opened to pour the liquid back into the mixing tank 1 from the top opening.
[0036] Specifically, a drive motor 10 is mounted on the fixed top cover 7, and the output shaft of the drive motor 10 is connected to the stirring shaft 9 to drive the eccentric stirring paddle 3 to rotate. Preferably, a digital display device 11 is mounted on the drive motor 10 to display the rotational speed of the eccentric stirring paddle 3. The digital display device 11 is prior art, and its specific structure and connection method will not be described in detail here.
[0037] Optionally, a screen 12 is provided on the top of the mixing tank 1 at a position corresponding to the opening and closing top cover 8. By setting the screen 12, foam in the suspension can be filtered out when the suspension is poured into the mixing tank 1 from the external material bucket. To facilitate cleaning of the screen 12, the screen 12 is detachably connected to the top of the mixing tank 1.
[0038] Preferably, to facilitate the installation of the screen 12, a bracket 13 is provided at the top of the mixing tank 1 corresponding to the position of the opening and closing top cover 8, and the bracket 13 is fixed to the inner wall of the mixing tank 1. The screen 12 is mounted on the bracket 13 and detachably connected to the bracket 13. The specific connection method is not limited; it can be a snap-fit connection or a bolt connection. The specific shape of the screen 12 is not limited; it can be flat or frame-shaped. In some embodiments, the screen 12 is set as a semi-circular screen frame. A symmetrically arranged bracket 13 is fixed at the top of the mixing tank 1 opposite to the opening and closing top cover 8, and the semi-circular screen frame can be placed on the bracket 13, snapped between the inner wall of the mixing tank 1 and the bracket 13. To facilitate the handling of the screen frame, a handle 21 is fixed on the screen frame.
[0039] Preferred, such as Figure 1 As shown, the bottom of the mixing tank 1 is designed as an inclined surface, with the side of the inclined surface near the slurry outlet 4 being lower than the side away from the slurry outlet 4. This inclined surface facilitates the entry of the suspension at the bottom into the slurry outlet 4. The inclination angle α of the inclined surface is not specifically limited. Preferably, the inclination angle α is set to 4–6°.
[0040] Optionally, a flow guiding groove 14 is provided on the inclined surface facing the slurry outlet 4. By providing the flow guiding groove 14, it is more convenient to guide the suspension at the bottom into the slurry outlet 4. Specifically, the width of the flow guiding groove 14 is smaller than the diameter of the slurry outlet 4, and the length of the flow guiding groove 14 is smaller than the radius of the slurry mixing tank 1.
[0041] Specifically, such as Figure 1 and Figure 3 As shown, a first hinge seat 15 is fixed to the lower side of the mixing tank 1, away from the outlet 4. The first hinge seat 15 is hinged to the movable end of the lifting device 6. A second hinge seat 16 is fixed to the base 2, and the second hinge seat 16 is hinged to the fixed end of the lifting device 6. The specific form of the lifting device 6 is not limited; it can be a pneumatic cylinder or a hydraulic cylinder. In some embodiments, the base 2 is configured as a box. A first connecting member 17 is fixed to the bottom of the mixing tank 1 near the outlet 4, and a second connecting member 18 is fixed to the opposite position of the base 2. The first connecting member 17 and the second connecting member 18 are rotatably connected. A second hinge seat 16 is fixed to the inner wall of the box on the side away from the outlet 4, and the fixed end of the lifting device 6 is hinged to the second hinge seat 16. A connecting block 19 is fixed to the movable end of the lifting device 6, and the connecting block 19 is hinged to the first hinge seat 15 fixed below the mixing tank 1.
[0042] Optionally, to facilitate observation of the slurry discharge from outlet 4 and ensure normal production, the inner wall of the slurry mixing tank 1 is equipped with graduation lines, which are not shown in the figure. By observing the liquid level of the suspension, it can be determined whether outlet 4 is supplying liquid to the fluidized bed normally.
[0043] Optionally, casters 20 are provided at the bottom of the base 2. To facilitate the movement of the mixing tank 1, casters 20 are installed at the four corners of the base 2, and the casters 20 are equipped with braking devices.
[0044] Example: A suspension mixing tank includes a mixing tank body 1 and a base 2. The top half of the mixing tank body 1 is covered by a fixed top cover 7, and the other half is covered by a hinged top cover 8. The fixed top cover 7 is bolted to the top of the mixing tank body 1, and the hinged top cover 8 is hinged to the fixed top cover 7. An eccentric stirring paddle 3 is installed inside the mixing tank body 1. The stirring shaft 9 of the eccentric stirring paddle 3 is vertically arranged and rotatably connected to the fixed top cover 7, causing the stirring shaft 9 of the eccentric stirring paddle 3 to deviate from the central axis of the mixing tank body 1. A drive motor 10 is mounted on the fixed top cover 7, and the output shaft of the drive motor 10 is connected to the stirring shaft 9. A digital display device 11 is mounted on the drive motor 10. A symmetrically arranged bracket 13 is fixed at the top of the mixing tank 1, corresponding to the position of the opening and closing top cover 8. A screen 12 is placed on the bracket 13. The screen 12 is set as a semi-circular screen frame and is engaged between the inner wall of the mixing tank 1 and the bracket 13. A handle 21 is fixed on the screen frame. The inner wall of the mixing tank 1 is provided with graduation lines. A slurry outlet 4 is provided on one side of the bottom of the mixing tank 1. A slurry outlet valve 5 is installed on the slurry outlet 4. The bottom of the mixing tank 1 is set as an inclined surface, and the side of the inclined surface near the slurry outlet 4 is lower than the side away from the slurry outlet 4. The inclination angle of the inclined surface is set to 5°. A flow guide groove 14 is provided on the inclined surface facing the slurry outlet 4. The bottom of the flow guide groove 14 is set as an arc. The width of the flow guide groove 14 is smaller than the diameter of the slurry outlet 4, and the length of the flow guide groove 14 is smaller than the radius of the mixing tank 1. The base 2 is set below the mixing tank, and a lifting device 6 is installed on the side of the base 2 away from the slurry outlet 4. In this embodiment, the lifting device 6 is configured as a cylinder. The base 2 is configured as a box, and a first connecting member 17 is fixed to the bottom of the mixing tank 1 near the slurry outlet 4. A second connecting member 18 is fixed to the opposite position of the base 2, and the first connecting member 17 and the second connecting member 18 are rotatably connected. A second hinge seat 16 is welded to the inner wall of the box on the side away from the slurry outlet 4, and the fixed end of the lifting device 6 is hinged to the second hinge seat 16. A connecting block 19 is fixed to the movable end of the lifting device 6, and the connecting block 19 is hinged to the first hinge seat 15 welded to the bottom of the mixing tank 1. Universal wheels 20 are installed at the four corners of the base 2, and the universal wheels 20 are equipped with brake devices.
[0045] The advantages and positive effects of this utility model are:
[0046] 1. By setting an eccentric stirring paddle, the dead zone of the stirring is reduced, the uniformity of stirring is improved, the risk of suspension sedimentation is reduced, and the stirring effect is guaranteed.
[0047] 2. By setting up a lifting device, it is easier for the suspension at the bottom to flow into the slurry outlet, reducing the amount of suspension remaining at the bottom.
[0048] 3. By setting the bottom of the mixing tank as an inclined surface and setting a flow guide groove, the flow of the suspension at the bottom can be effectively promoted, ensuring the amount of feed when preparing the drug solution, thereby ensuring product quality.
[0049] 4. Simple structure and easy operation.
[0050] The embodiments of this disclosure have been described in detail above with reference to the accompanying drawings. It should be noted that implementations not illustrated or described in the drawings or the main text of the specification are forms known to those skilled in the art and have not been described in detail. Furthermore, the definitions of the various components described above are not limited to the specific structures, shapes, or methods mentioned in the embodiments, and those skilled in the art can easily modify or substitute them.
[0051] The embodiments of this utility model have been described in detail above, but the content described is only a preferred embodiment of this utility model and should not be considered as limiting the scope of implementation of this utility model. All equivalent changes and improvements made in accordance with the claims of this utility model should still fall within the patent coverage of this utility model.
Claims
1. A suspension preparation tank, characterized in that, include: The mixing tank (1) is equipped with an eccentric stirring paddle (3) inside, and the bottom side of the mixing tank (1) is provided with a slurry outlet (4); The base (2) is located below the mixing tank (1), with one side rotatably connected to the side of the mixing tank (1) where the slurry outlet (4) is located, and the other side is provided with a lifting device (6) that allows the mixing tank (1) to tilt toward the side where the slurry outlet (4) is located.
2. The suspension mixing tank according to claim 1, characterized in that: The top of the mixing tank (1) is provided with a fixed top cover (7) on one side and an openable top cover (8) on the other side. The eccentric stirring paddle (3) is mounted on the fixed top cover (7) and is rotatably connected to the fixed top cover (7).
3. A suspension mixing tank according to claim 2, characterized in that: The fixed top cover (7) is provided with a drive motor (10), which is used to drive the eccentric stirring paddle (3) to rotate. The drive motor (10) is provided with a digital display device (11) for displaying the rotation speed of the eccentric stirring paddle (3).
4. A suspension mixing tank according to claim 2 or 3, characterized in that: A screen (12) is provided at the top of the mixing tank (1) at the position corresponding to the opening and closing top cover (8), and the screen (12) is detachably connected to the top of the mixing tank (1).
5. A suspension mixing tank according to claim 4, characterized in that: The top of the mixing tank (1) is provided with a bracket (13) at a position corresponding to the opening and closing top cover (8), and the screen (12) is set on the bracket (13) and detachably connected to the bracket (13).
6. A suspension mixing tank according to any one of claims 1-3 and 5, characterized in that: The bottom of the mixing tank (1) is set as an inclined surface, and the side of the inclined surface near the slurry outlet (4) is lower than the side away from the slurry outlet (4).
7. A suspension mixing tank according to claim 6, characterized in that: A flow guide groove (14) is provided on the inclined surface facing the slurry outlet (4).
8. A suspension mixing tank according to any one of claims 1-3, 5 and 7, characterized in that: A first hinge seat (15) is provided on the side of the mixing tank (1) away from the slurry outlet (4). The first hinge seat (15) is hinged to the movable end of the lifting device (6). A second hinge seat (16) is provided on the base (2). The second hinge seat (16) is hinged to the fixed end of the lifting device (6).
9. A suspension mixing tank according to claim 8, characterized in that: The inner wall of the mixing tank (1) is provided with scale lines.
10. A suspension mixing tank according to any one of claims 1-3, 5, 7 and 9, characterized in that: The base (2) is equipped with casters (20) at its bottom.