Replaceable sealing film type sealing reaction disc

Abstract

The utility model provides a sealing reaction disc with a replaceable sealing film, and belongs to the technical field of reaction discs. In order to solve the problems that the sealing reaction disc is poor in sealing performance and inconvenient to use, the sealing film replaceable type sealing reaction disc comprises an upper cover plate and a tray, the tray is used for containing a reaction bottle, and the upper cover plate detachably covers the tray through a first fastener and is used for sealing the reaction bottle located in the tray; the bottom of the upper cover plate is detachably connected with a sealing assembly through a second fastener, the sealing assembly comprises a silica gel pad, a sealing film and a film pressing sheet which are stacked, the silica gel pad is attached to the upper cover plate, the thickness of the silica gel pad is 3.5-5 mm, the film pressing sheet is in a hollow frame shape and attached to the edge of the sealing film, and the sealing film is clamped between the film pressing sheet and the silica gel pad through the second fastener. According to the reaction disc, the silica gel pad with the thickness of 3.5-5 mm is adopted, the sealing performance is improved, meanwhile, the membrane pressing piece, the sealing membrane, the silica gel pad and the upper cover plate are detachably connected together through the second fastener, the sealing membrane can be replaced, and therefore the use convenience of the reaction disc is improved.

Description

Technical Field

[0001] This application relates to the field of reaction disk technology, and more particularly to a replaceable sealing membrane type reaction disk. Background Technology

[0002] Currently, the chemical industry typically uses 96-well 1ml reaction trays for high-throughput parallel reactions. Commercially available reaction trays usually consist of a top cover, a top sealing plate (made of a composite of 2mm silicone and 0.1mm polytetrafluoroethylene film), a well plate, a buffer plate, and a tray.

[0003] In actual use, it was found that the sealing of this type of reaction plate is insufficient, and some reaction flasks placed inside are prone to leakage; at the same time, the upper sealing plate needs to be thoroughly cleaned after each use to avoid contamination of the next reaction, which leads to inconvenience in use. Utility Model Content

[0004] The purpose of this application is to solve the problems of poor sealing performance and inconvenience in use of existing sealed reaction discs. Therefore, this application provides a replaceable sealing membrane type sealed reaction disc. By using a silicone gasket with a thickness of 3.5-5mm, the sealing performance is improved. At the same time, by using a second fastener to detachably connect the pressure plate, sealing membrane, silicone gasket and top cover plate together, the sealing membrane can be replaced, thereby improving the ease of use of the reaction disc.

[0005] This application provides a replaceable sealing membrane type sealing reaction tray, including an upper cover and a tray. The tray is used to accommodate reaction flasks. The upper cover is detachably covered on the tray by a first fastener and is used to seal the reaction flasks located in the tray. A sealing assembly is detachably connected to the bottom of the upper cover by a second fastener. The sealing assembly includes a silicone pad, a sealing membrane, and a pressure plate stacked on top of each other. The silicone pad is attached to the upper cover and has a thickness of 3.5-5mm. The pressure plate is a hollow frame shape and is attached to the edge of the sealing membrane. The second fastener clamps the sealing membrane between itself and the silicone pad.

[0006] By adopting the above technical solution, a silicone pad with a thickness of 3.5-5mm is used, which allows for a larger deformation range in the thickness direction, thus providing better tolerance for the length of the reaction flask and improving the sealing performance when the sealing component covers multiple reaction flasks. At the same time, by using a second fastener to detachably connect the pressure film, sealing film, silicone pad and top cover plate together, the sealing film can be replaced after use to maintain cleanliness without the need for cleaning, thereby improving the ease of use of the reaction plate.

[0007] In some embodiments, the first fastener is an M5 screw, and a threaded sleeve adapted to the M5 screw is provided at a corresponding position on the tray.

[0008] By adopting the above technical solution, the upper cover plate and tray are locked with M5 screws, which can quickly install the equipment and ensure the locking force, thereby ensuring the reliability of the seal.

[0009] In some embodiments, the second fastener is a screw, and the top of the screw has a hand-tightening portion.

[0010] The above technical solution facilitates the replacement of the sealing membrane and improves ease of use.

[0011] In some embodiments, the tray has a first thickness and a plurality of grooves for accommodating the reaction flask are formed in the thickness direction of the tray, and a cushioning pad is provided at the bottom of the grooves.

[0012] By adopting the above technical solution, a groove for accommodating the reaction flask is formed by slotting a tray with a first thickness. That is, the tray and perforated plate that are separated in the existing reaction plate are set as grooves, and a buffer pad is set at the bottom of the groove. This can not only ensure the buffering effect on the reaction flask, but also reduce the resistance to the conduction of reaction heat and improve the reaction effect.

[0013] In some embodiments, the sealing film is a polytetrafluoroethylene film with a thickness of 0.15-0.3 mm.

[0014] In some embodiments, the tray is a rectangular tray, the top cover is a rectangular plate adapted to the size of the tray, the circumferential edge of the tray has a boss with a first thickness, and four first fasteners are provided, which are detachably connected to the four corners of the boss respectively.

[0015] In some embodiments, four second fasteners are provided, located close to the first fasteners and directly opposite the boss of the tray.

[0016] Other features and corresponding beneficial effects of this application will be described in the latter part of the specification, and it should be understood that at least some of the beneficial effects will become obvious from the description in this application. Attached Figure Description

[0017] Figure 1 This is a top view of the structure of this application;

[0018] Figure 2 for Figure 1 Schematic diagram of sectional view AA.

[0019] Explanation of reference numerals in the attached figures:

[0020] 1. First fastener; 2. Gasket; 3. Top cover plate; 4. Silicone gasket; 5. Sealing film; 6. Pressure plate; 7. Second fastener; 8. Threaded sleeve; 9. Reaction flask; 10. Buffer pad; 11. Tray. Detailed Implementation

[0021] The following specific embodiments illustrate the implementation of this application. Those skilled in the art can easily understand other advantages and effects of this application from the content disclosed in this specification. Although the description of this application is presented in conjunction with preferred embodiments, this does not mean that the features of this application are limited to this embodiment. On the contrary, the purpose of describing the application in conjunction with embodiments is to cover other options or modifications that may be derived based on the claims of this application. To provide a thorough understanding of this application, many specific details will be included in the following description. This application may also be implemented without using these details. Furthermore, to avoid confusion or obscuring the focus of this application, some specific details will be omitted in the description. It should be noted that, unless otherwise specified, the embodiments and features in the embodiments of this application can be combined with each other.

[0022] It should be noted that in this specification, similar reference numerals and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0023] In the description of this application, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used solely for the convenience of describing this application and for simplification, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, features defined with "first," "second," etc., may explicitly or implicitly include one or more of that feature. In the description of this application, unless otherwise stated, "a plurality of" means two or more. Unless otherwise explicitly specified and limited, the terms "installed," "connected," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; a mechanical connection or an electrical connection; a direct connection or an indirect connection through an intermediate medium; or a connection within two elements. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0024] It should be noted that similar reaction trays on the market typically have an adhesive structure between the top cover plate 3 and the top sealing plate, and the top sealing plate is made of a composite of 2mm silicone and 0.1mm polytetrafluoroethylene film. This structure means that after each reaction, the top cover plate 3 must be thoroughly rinsed to prevent contamination of the next reaction, resulting in inconvenience and an inability to guarantee contamination-free operation. Furthermore, the top sealing plate is too thin, while the reaction flasks 9 have length tolerances. A single reaction usually involves multiple reaction flasks 9 filling the tray 11, which can easily lead to insufficient sealing of some reaction flasks 9 during the reaction, causing leakage from those flasks.

[0025] Therefore, this application provides a replaceable sealing membrane type sealing reaction plate. By using a silicone pad 4 with a thickness of 3.5-5mm, the sealing performance is improved. At the same time, by using a second fastener 7 to detachably connect the pressure plate 6, sealing membrane 5, silicone pad 4 and upper cover plate 3 together, the sealing membrane can be replaced, thereby improving the ease of use of the reaction plate and ensuring no contamination.

[0026] Specifically, please see Figure 1-2 , Figure 1 This is a top view of the structure of this application; Figure 2 for Figure 1 Schematic diagram of sectional view AA.

[0027] This application provides a replaceable sealing membrane type sealing reaction tray, including an upper cover plate 3 and a tray 11. The tray 11 is used to accommodate reaction bottles 9. The upper cover plate 3 is detachably covered on the tray 11 by a first fastener 1 and is used to seal the reaction bottles 9 located in the tray 11.

[0028] A sealing assembly is detachably connected to the bottom of the top cover plate 3 via a second fastener 7. The sealing assembly includes a silicone pad 4, a sealing membrane 5, and a pressure plate 6 stacked together.

[0029] The silicone pad 4 is attached to the top cover plate 3, and its thickness is 3.5-5mm, such as 3.5mm, 4mm, 4.5mm, etc., which allows it to have a larger deformation range in the thickness direction and is compatible with the length tolerance of the reaction bottle 9, thus providing better tolerance for the length of the reaction bottle 9, while also taking into account cost control and improving the sealing performance when the sealing component covers multiple reaction bottles 9.

[0030] The pressure plate 6 is a hollow frame shape that fits the edge of the sealing film 5 and is clamped between it and the silicone pad 4 by the second fastener 7, which improves the flatness of the sealing film 5. Preferably, the pressure plate 6 is a metal sheet, such as aluminum or stainless steel, which balances thinness and strength.

[0031] This method uses a second fastener 7 to detachably connect the pressure plate 6, sealing film 5, silicone pad 4 and top cover 3 together, so that after use, the sealing film 5 can be replaced to maintain cleanliness without cleaning, thereby improving the ease of use of the reaction plate and ensuring no contamination compared to cleaning.

[0032] It should also be noted that similar reaction trays on the market usually use M3 flathead screws to lock the top cover 3 and tray 11 when sealing the 1ML reaction bottle 9. Since M3 screws are very easy to strip and have limited torque, in order to ensure the locking force, 9 M3 screws are required, that is, M3 screws are set in the middle and both sides, forming a 3*3 distribution, which makes the operation cumbersome. Moreover, if some M3 screws strip, it will also easily lead to a decrease in the reliability of locking, thereby reducing the sealing reliability of the reaction tray.

[0033] Therefore, in one embodiment, the first fastener 1 is an M5 screw, and a threaded sleeve 8 adapted to the M5 screw is provided at the corresponding position on the tray 11. By using M5 screws to lock the upper cover plate 3 and the tray 11, the reaction disc can be installed faster than with M3 screws, while ensuring locking force and thus ensuring reliable sealing.

[0034] Preferably, a gasket 2 is provided between the first fastener 1 and the upper cover to further improve the sealing performance.

[0035] In one embodiment, the second fastener 7 is a screw with a hand-tightening portion at the top, facilitating the replacement of the sealing membrane 5 and improving ease of use. Furthermore, since the sealing assembly also ensures a seal on the reaction flask 9 during sealing via the first fastener 1, the second fastener 7 connecting the sealing assembly and the top cover 3 can be a standard screw, thus controlling costs.

[0036] It should also be noted that similar reaction trays on the market have a three-layer separation structure at the bottom, including a tray, a perforated plate on top of the tray (with several holes for inserting reaction flask 9), and a buffer rubber plate between the tray and the perforated plate. The three are connected by screws. During reaction heating, heat is conducted sequentially through the bottom of the tray and the buffer rubber plate to the reaction flask. Because the buffer rubber plate completely isolates the reaction flask and the tray, it hinders heat conduction, resulting in poor reaction performance.

[0037] Therefore, in one embodiment, the tray 11 has a first thickness and a plurality of grooves for accommodating the reaction bottle 9 are formed from the thickness direction of the tray 11. That is, the tray 11 and the perforated plate separated in the existing reaction plate are set as a tray 11 with a first thickness and grooved, so that the grooves are surrounded by the tray in the circumferential direction. The tray is usually made of metal material, such as aluminum, so that the reaction bottle in the groove is in direct contact with the tray in the circumferential direction, thereby improving the heat conduction efficiency.

[0038] Preferably, a buffer pad 10 is provided at the bottom of the groove to ensure a buffering effect on the reaction flask 9.

[0039] In one embodiment, the sealing membrane 5 is a polytetrafluoroethylene (PTFE) membrane with a thickness of 0.15-0.3 mm, such as 0.15 mm, 0.2 mm, 0.25 mm, etc. Compared with the 0.1 mm PTFE membrane used in conventional reaction dishes, this thickness of PTFE membrane facilitates manual membrane replacement.

[0040] In one specific embodiment, the tray 11 is a rectangular tray, the upper cover plate 3 is a rectangular plate adapted to the size of the tray 11, and the circumferential edge of the tray 11 is formed with a boss with a first thickness. Four first fasteners 1 are provided and are detachably connected to the four corners of the boss respectively.

[0041] In one specific embodiment, four second fasteners 7 are provided, located close to the first fastener 1 and facing the boss of the tray 11, thereby avoiding the reaction bottle 9 in the tray 11.

[0042] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A replaceable sealing membrane type sealing reaction tray, comprising an upper cover and a tray, the tray for accommodating reaction flasks, the upper cover being detachably mounted on the tray by a first fastener and for sealing the reaction flasks located within the tray; characterized in that, The bottom of the upper cover plate is detachably connected to a sealing assembly via a second fastener. The sealing assembly includes a silicone pad, a sealing film, and a pressure film sheet stacked on top of each other. The silicone pad is attached to the upper cover plate and has a thickness of 3.5-5mm. The pressure film sheet is a hollow frame shape and is attached to the edge of the sealing film. The second fastener clamps the sealing film between itself and the silicone pad.

2. The replaceable sealing diaphragm type sealed reaction disk according to claim 1, characterized in that, The first fastener is an M5 screw, and a threaded sleeve adapted to the M5 screw is provided at the corresponding position of the tray.

3. The replaceable sealing diaphragm type sealed reaction disk according to claim 1, characterized in that, The second fastener is a screw, and the top of the screw has a hand-tightening portion.

4. The replaceable sealing diaphragm type sealed reaction disk according to claim 1, characterized in that, The tray has a first thickness and has a plurality of grooves for accommodating the reaction flasks formed along the thickness direction of the tray. A cushioning pad is provided at the bottom of the grooves.

5. The replaceable sealing diaphragm type sealed reaction disk according to claim 1, characterized in that, The sealing membrane is a polytetrafluoroethylene membrane with a thickness of 0.15-0.3 mm.

6. The replaceable sealing diaphragm type sealed reaction disk according to claim 1, characterized in that, The tray is a rectangular tray, the top cover is a rectangular plate adapted to the size of the tray, and the circumferential edge of the tray has a boss with a first thickness. The first fastener is provided in four parts, and is detachably connected to the four corners of the boss respectively.

7. The replaceable sealing diaphragm type sealed reaction disk according to claim 6, characterized in that, The second fastener is provided in four parts, close to the first fastener and directly opposite the boss of the tray.

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