Sample crushing treatment device for gene detection

Abstract

The utility model discloses a sample crushing treatment device for gene detection, which relates to the technical field of samples for gene detection and comprises a base, a vertical plate is fixedly arranged on the upper portion of the base, a threaded rod is rotatably connected to one side of the vertical plate, a sliding block is sleeved on the outer side of the threaded rod in a threaded mode, and a supporting plate is fixedly arranged on one side of the sliding block. According to the sample crushing treatment device for gene detection, the threaded rod is arranged, the height of the amplitude-change pole can be adjusted only by rotating the threaded rod forwards and backwards, in the height adjusting process of the amplitude-change pole, the height of the amplitude-change pole can be adjusted, the height of the amplitude-change pole can be adjusted, and the height of the amplitude-change pole can be adjusted. And secondary locking operation is not needed, so that the use convenience of the sample crushing treatment device for gene detection is effectively improved.

Description

Technical Field

[0001] This utility model relates to the field of sample technology for gene detection, specifically a sample crushing and processing device for gene detection. Background Technology

[0002] Genes are the basic units of heredity, consisting of DNA or RNA sequences that carry genetic information. Through replication, they pass this information to the next generation, guiding protein synthesis to express the genetic information they carry, thereby controlling the expression of traits in an organism. Genetic testing is a technique that analyzes DNA from blood, other bodily fluids, or cells. It involves taking peripheral venous blood or other tissue cells from the subject, amplifying their genetic information, and then using specialized equipment to analyze the DNA molecules in the cells. This analysis reveals the types of genes, gene defects, and whether their expression functions are normal, allowing individuals to understand their genetic information, identify the causes of diseases, or predict their risk of developing certain illnesses.

[0003] In the prior art, CN220788594U discloses a sample crushing and processing device for gene detection, which relates to the field of gene detection technology. This sample crushing and processing device for gene detection includes an ultrasonic generator, a cable installed on the ultrasonic generator, a transducer installed at one end of the cable, a protective tube installed at the bottom of the transducer, an amplitude transformer installed at the bottom of the protective tube, a sleeve fitted on the outside of the amplitude transformer, a conduit mounting hole opened on one side wall of the sleeve, an air cavity opened in the sleeve, an exhaust hole opened at the bottom of the air cavity, and a second through hole opened in the middle of the sleeve.

[0004] While the above scheme has many advantages, it also has the following disadvantages: the device requires loosening the second fastening bolt to adjust the height of the amplitude rod, and since the height adjustment is not restricted by the second fastening bolt, the staff needs to manually support and adjust it. After the height of the amplitude rod is adjusted, the second fastening bolt needs to be tightened again in reverse to fix it. This method is cumbersome and reduces the convenience of adjusting the sample crushing and processing device for gene detection. Utility Model Content

[0005] The purpose of this invention is to provide a sample crushing and processing device for gene detection, so as to solve the problem of low adjustability of current sample crushing and processing devices for gene detection in the prior art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a sample crushing and processing device for gene detection, comprising a base, a vertical plate fixedly disposed on the upper part of the base, a threaded rod rotatably connected to one side of the vertical plate, a slider threadedly sleeved on the outer side of the threaded rod, a support plate fixedly disposed on one side of the slider, an amplitude-changing mechanism disposed on the support plate, and a container disposed on the upper part of the base, the container being located directly below the amplitude-changing mechanism.

[0007] Preferably, the amplitude-changing mechanism includes a protective tube mounted on a support plate, an amplitude-changing rod at the bottom of the protective tube, a transducer at the top of the protective tube, an ultrasonic generator mounted on the base, and a cable mounted on the ultrasonic generator, with one end of the cable electrically connected to the transducer.

[0008] Preferably, a sleeve is rotatably sleeved on the outside of the amplitude rod, and a connecting rod arranged in a circumferential array is fixedly connected between the sleeve and the protective tube. A nozzle arranged in a circumferential array is fixedly connected to the bottom of the sleeve, and a conveying mechanism for conveying gas into the sleeve is provided on the support plate.

[0009] Preferably, the conveying mechanism includes an air pump mounted on a support plate, and a connecting conduit is fixedly connected between the air pump outlet and the sleeve.

[0010] Preferably, a worm gear is rotatably connected to the bottom end of the protective tube, a worm is meshed with one side of the worm gear, and a fixing block is rotatably sleeved at both ends of the worm. The fixing block is fixedly set at the bottom end of the protective tube, the worm gear is fixedly sleeved on the outside of the amplitude transformer, and the worm gear and the worm are both located between the sleeve and the protective tube. The amplitude transformer rotates at the bottom end of the protective tube.

[0011] Preferably, a gear is fixedly provided at the end of the worm gear, and a rack is meshed with one side of the gear, the rack being fixedly provided on one side of the vertical plate.

[0012] Preferably, a servo motor is fixedly installed at the top of the vertical plate, the output shaft of the servo motor is fixedly connected to the top of the threaded rod, and the servo motor is electrically connected to the power supply.

[0013] Preferably, a cover plate is fixedly fitted on the outer side of the sleeve, and a sealing ring is provided at the bottom of the cover plate.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] 1. By setting a threaded rod, the height of the amplitude transformer can be adjusted simply by rotating the threaded rod in both directions. During the height adjustment process, no secondary locking operation is required, thus effectively improving the ease of use of the sample crushing and processing device for gene detection.

[0016] 2. This application incorporates a rotatable amplitude rod and a worm gear, gear, and rack structure that work together to clean residues from all angles of the amplitude rod using the nozzle. This avoids the problem of the amplitude rod being unable to be effectively cleaned when it is away from the nozzle area, thus effectively improving the cleaning effect of the sample crushing and processing device for gene detection. Attached Figure Description

[0017] Figure 1 This is a three-dimensional schematic diagram of the sample crushing and processing device for gene detection according to the present invention;

[0018] Figure 2 This is a three-dimensional schematic diagram of the cooperation between the amplitude-changing mechanism and the conveying mechanism of a sample crushing and processing device for gene detection according to this utility model;

[0019] Figure 3 This is a three-dimensional schematic diagram of the rack and support plate of a sample crushing and processing device for gene detection according to the present invention.

[0020] Figure 4 This is a three-dimensional schematic diagram of the rack, cover plate and worm gear of a sample crushing and processing device for gene detection according to the present invention.

[0021] The following are the labeling elements in the diagram: 1. Base; 2. Vertical plate; 3. Threaded rod; 4. Slider; 5. Support plate; 6. Lamp mechanism; 601. Protective tube; 602. Lamp rod; 603. Transducer; 7. Container; 8. Sleeve; 9. Conveying mechanism; 901. Air pump; 902. Connecting conduit; 10. Worm gear; 11. Worm; 12. Gear; 13. Rack; 14. Servo motor; 15. Cover plate. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Example: Figure 1 - Figure 4 As shown, this utility model provides a technical solution for a sample crushing and processing device for gene detection, including a base 1, a vertical plate 2 fixedly installed on the upper part of the base 1, a threaded rod 3 rotatably connected to one side of the vertical plate 2, a slider 4 threadedly sleeved on the outer side of the threaded rod 3, a support plate 5 fixedly installed on one side of the slider 4, an amplitude-changing mechanism 6 installed on the support plate 5, and a container 7 installed on the upper part of the base 1, with the container 7 located directly below the amplitude-changing mechanism 6.

[0024] A vertical groove is provided on one side of the vertical plate 2. The threaded rod 3 is rotatably connected to the inner wall of the vertical groove. The slider 4 slides in the cavity of the vertical groove. By rotating the threaded rod 3, the threaded rod 3 drives the support plate 5 to rise and fall using the slider 4.

[0025] like Figure 2 As shown, the amplitude-changing mechanism 6 includes a protective tube 601 mounted on the support plate 5, an amplitude-changing rod 602 at the bottom of the protective tube 601, a transducer 603 at the top of the protective tube 601, an ultrasonic generator mounted on the base 1, a cable mounted on the ultrasonic generator, and one end of the cable electrically connected to the transducer 603.

[0026] The height of the amplitude transformer 602 is adjusted and inserted into the container 7, bringing it into contact with the biological solution in the container 7. The ultrasonic generator is then activated, converting mains power into 18-21 kHz alternating electrical energy to supply the transducer 603. A barium zirconate titanate piezoelectric vibrator is installed inside the transducer 603. This barium zirconate titanate piezoelectric vibrator undergoes elastic deformation at a frequency of 18-21 kHz in response to the alternating voltage, causing the transducer 603 to vibrate longitudinally. The vibration waves generate a cavitation effect through the amplitude transformer 602 immersed in the biological solution, exciting the biological particles in the solution to vibrate violently, thereby pulverizing them. Both the transducer 603 and the ultrasonic generator are existing technologies, and their specific forms and usage are not described in detail in this application.

[0027] like Figure 2 As shown, a sleeve 8 is rotatably sleeved on the outside of the amplitude rod 602. A connecting rod distributed in a circular array is fixedly connected between the sleeve 8 and the protective tube 601. A nozzle distributed in a circular array is fixedly connected to the bottom of the sleeve 8. A conveying mechanism 9 for conveying gas into the sleeve 8 is provided on the support plate 5.

[0028] like Figure 2 As shown, the conveying mechanism 9 includes an air pump 901 mounted on the support plate 5, and a connecting conduit 902 is fixedly connected between the air outlet end of the air pump 901 and the sleeve 8.

[0029] Start the air pump 901. The air pump 901 draws in air, which passes through the connecting conduit 902 and then enters the sleeve 8. The air is then sprayed out by the nozzle. The high-speed flowing gas blows onto the outer wall of the amplitude rod 602, and the residue on the outer wall of the amplitude rod 602 is blown into the container 7.

[0030] like Figure 2As shown, a worm gear 10 is rotatably connected to the bottom end of the protective tube 601. A worm 11 is meshed with one side of the worm gear 10. Fixed blocks are rotatably sleeved at both ends of the worm 11. The fixed blocks are fixedly set at the bottom end of the protective tube 601. The worm gear 10 is fixedly sleeved on the outside of the amplitude rod 602. The worm gear 10 and the worm 11 are both located between the sleeve 8 and the protective tube 601. The amplitude rod 602 rotates at the bottom end of the protective tube 601.

[0031] like Figure 1 , Figure 2 and Figure 4 As shown, a gear 12 is fixedly installed at the end of the worm gear 11, and a rack 13 is meshed with one side of the gear 12. The rack 13 is fixedly installed on one side of the vertical plate 2.

[0032] When adjusting the height of the amplitude rod 602, the nozzle is activated to blow air onto the surface of the amplitude rod 602. The gear 12 rotates through the rack 13, and the gear 12 drives the worm wheel 10 to rotate through the worm 11. The worm wheel 10 drives the amplitude rod 602 to rotate, thus changing the area of ​​the amplitude rod 602 located in front of the nozzle, so that the entire outer wall of the amplitude rod 602 can be cleaned by the nozzle and blown by air.

[0033] like Figure 1 - Figure 3 As shown, a servo motor 14 is fixedly installed at the top of the vertical plate 2. The output shaft of the servo motor 14 is fixedly connected to the top of the threaded rod 3. The servo motor 14 is electrically connected to the power supply.

[0034] The servo motor 14 drives the threaded rod 3 to rotate forward or backward.

[0035] like Figure 2 As shown, a cover plate 15 is fixedly fitted on the outside of the sleeve 8, and a sealing ring is provided at the bottom of the cover plate 15.

[0036] The top opening of container 7 is covered by cover plate 15, and the sealing ring can improve the sealing between cover plate 15 and container 7.

[0037] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A sample crushing and processing device for gene detection, comprising a base (1), characterized in that: A vertical plate (2) is fixedly installed on the upper part of the base (1). A threaded rod (3) is rotatably connected to one side of the vertical plate (2). A slider (4) is threaded on the outer side of the threaded rod (3). A support plate (5) is fixedly installed on one side of the slider (4). A variable amplitude mechanism (6) is installed on the support plate (5). A container (7) is installed on the upper part of the base (1). The container (7) is located directly below the variable amplitude mechanism (6).

2. The sample pulverizing and processing device for gene detection according to claim 1, characterized in that: The amplitude-changing mechanism (6) includes a protective tube (601) installed on the support plate (5), an amplitude-changing rod (602) is provided at the bottom of the protective tube (601), and a transducer (603) is provided at the top of the protective tube (601).

3. The sample pulverizing and processing device for gene detection according to claim 2, characterized in that: The outside of the amplitude rod (602) is rotatably fitted with a sleeve (8), and the sleeve (8) and the protective tube (601) are fixedly connected by a connecting rod distributed in a circumferential array. The bottom of the sleeve (8) is fixedly connected to a nozzle distributed in a circumferential array, and the support plate (5) is provided with a conveying mechanism (9) for conveying gas into the sleeve (8).

4. The sample pulverizing and processing device for gene detection according to claim 3, characterized in that: The conveying mechanism (9) includes an air pump (901) mounted on a support plate (5), and a connecting conduit (902) is fixedly connected between the air outlet end of the air pump (901) and the sleeve (8).

5. The sample pulverizing and processing device for gene detection according to claim 2, characterized in that: The bottom end of the protective tube (601) is rotatably connected to a worm gear (10), and a worm (11) is meshed with one side of the worm gear (10). Both ends of the worm (11) are rotatably fitted with fixing blocks, which are fixedly set at the bottom end of the protective tube (601). The worm gear (10) is fixedly fitted on the outside of the amplitude transformer (602). The worm gear (10) and the worm (11) are both located between the sleeve (8) and the protective tube (601).

6. The sample pulverizing and processing device for gene detection according to claim 5, characterized in that: A gear (12) is fixedly provided at the end of the worm (11), and a rack (13) is meshed with one side of the gear (12). The rack (13) is fixedly provided on one side of the vertical plate (2).

7. The sample pulverizing and processing device for gene detection according to claim 1, characterized in that: A servo motor (14) is fixedly installed at the top of the vertical plate (2), and the output shaft of the servo motor (14) is fixedly connected to the top of the threaded rod (3).

8. The sample pulverizing and processing device for gene detection according to claim 5, characterized in that: A cover plate (15) is fixedly fitted on the outside of the sleeve (8), and a sealing ring is provided at the bottom of the cover plate (15).

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