Chromatographic column protection device

Abstract

The utility model discloses a chromatographic column protection device which comprises a connecting pipe (1), one end of the connecting pipe (1) is provided with a first end plate (2), the other end of the connecting pipe (1) is provided with a second end plate (3), the first end plate (2) is provided with an external threaded pipe (4), and the second end plate (3) is provided with a first threaded hole (5). According to the utility model, the two ends of the chromatographic column can be connected, and the end parts do not need to be cut when the chromatographic column is reused.

Description

Technical Field

[0001] This utility model relates to a column protection device for chromatography. Background Technology

[0002] The chromatographic column is a crucial component of gas chromatography-mass spectrometry (GC-MS) systems, used to separate complex components. Its outer diameter is typically 0.53 μm, 0.32 μm, or 0.25 μm, and its length is usually 30 m, 50 m, or 60 m. During use, the column is connected to the injection port and detector via a column connector and a graphite or VESP gasket. The injection port connector is typically a hollow screw, allowing the column to pass through. The graphite gasket is also hollow; after the column passes through, tightening the screw deforms the graphite gasket, pressing it firmly onto the column for a seal. The mass spectrometer connector usually uses a hollow nut and a hollow VESP gasket for column connection. Other detectors are typically connected to the column using hollow screws and hollow graphite gaskets, similar to the injection port. The length of the column extending beyond the injection port and detector interface is fixed; usually, a portion is left unsecured and then trimmed to the desired length after the graphite or VESP gasket is tightened onto the column. Different chromatographic columns have different separation effects, so it is necessary to replace the chromatographic column when using it. The replaced chromatographic column is generally sealed at both ends with soft silicone to ensure that the chromatographic column is protected from contact with air under the protection of carrier gas.

[0003] The problem with existing practices is that when the column is sealed with soft silicone, some silicone may enter the column, causing blockage. Because the column's inner diameter is very small, it's difficult to detect whether silicone has entered. To prevent this, a portion of the column head usually needs to be cut off. Since the length of the column extending beyond the injection port and detector interface is fixed, the graphite or VESP pad needs to be replaced, and the column head is re-cut. This results in a change in column length, altering the original separation performance. Utility Model Content

[0004] The purpose of this invention is to provide a column protection device to solve the technical problems in the prior art. It can connect both ends of the column and does not require the ends to be cut when the column is reused.

[0005] This utility model provides a chromatographic column protection device, including a connecting tube, one end of which has a first end plate and the other end of which has a second end plate. The first end plate is provided with an external threaded tube, and the second end plate is provided with a first threaded hole.

[0006] In the aforementioned column protection device, preferably, the connecting tube is a copper tube or a steel tube, and the materials of the first end plate and the second end plate are the same as the material of the connecting tube.

[0007] In the aforementioned column protection device, preferably, the inner diameter of the connecting tube is 2cm-5cm, and the length of the connecting tube is 15cm-20cm.

[0008] In the aforementioned column protection device, preferably, an air inlet pipe is fixedly connected to the first end plate. The air inlet pipe is an L-shaped pipe, and the material of the air inlet pipe is the same as that of the connecting pipe. A valve is provided on the air inlet pipe.

[0009] In the aforementioned column protection device, preferably, a sealing cap is threaded onto the external threaded tube.

[0010] In the aforementioned column protection device, preferably, the first end plate is further provided with a second threaded hole.

[0011] Preferably, the aforementioned column protection device further includes a plug, which is threadedly connected to the first threaded hole or the second threaded hole.

[0012] Compared with the prior art, this utility model includes a connecting tube, one end of which has a first end plate and the other end of which has a second end plate. The first end plate has an externally threaded tube, and the second end plate has a first threaded hole. With this utility model, when the chromatographic column is not in use, the mass spectrometer end of the column is inserted into the externally threaded tube, and the hollow nut on the mass spectrometer end is threaded into the externally threaded tube. The injection end of the column is then inserted into the first threaded hole, and the hollow screw on the injection end is threaded into the first threaded hole. In this way, both ends of the chromatographic column are located within the connecting tube and effectively protected by it. When the column is reused, it does not need to be cut, thus the length of the column remains unchanged, and the separation performance is also unchanged. Attached Figure Description

[0013] Figure 1 This is the first axonometric drawing of this utility model;

[0014] Figure 2 This is the second isometric drawing of this utility model.

[0015] Explanation of reference numerals in the attached drawings: 1. Connecting pipe; 2. First end plate; 3. Second end plate; 4. External threaded pipe; 5. First threaded hole; 6. Air inlet pipe; 7. Valve; 8. Second threaded hole. Detailed Implementation

[0016] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0017] Embodiments of this utility model: such as Figure 1 and Figure 2 As shown, a chromatographic column protection device includes a connecting tube 1, one end of the connecting tube 1 has a first end plate 2, the other end of the connecting tube 1 has a second end plate 3, the first end plate 2 is provided with an external threaded tube 4, and the second end plate 3 is provided with a first threaded hole 5.

[0018] The first end plate 2 and the second end plate 3 are used to seal both ends of the connecting tube 1. The hollow nut on the chromatographic column can be connected by the external threaded tube 4 on the first end plate 2, so that one end of the chromatographic column is fixed in the connecting tube 1. The first threaded hole 5 on the second end plate 3 can be connected by the hollow screw on the chromatographic column, so that the other end of the chromatographic column is fixed in the connecting tube 1, thereby protecting both ends of the chromatographic column.

[0019] Specifically, the connecting pipe 1 is made of copper or steel, and in this embodiment, copper is preferred. The first end plate 2 and the second end plate 3 are made of the same material as the connecting pipe 1.

[0020] Furthermore, the inner diameter of the connecting pipe 1 is 2cm-5cm, preferably 3cm in this embodiment, and the length of the connecting pipe 1 is 15cm-20cm, preferably 18cm in this embodiment.

[0021] Setting a suitable length for the connecting tube 1 ensures that the two ends of the chromatographic column will not collide after being inserted into the connecting tube 1.

[0022] Furthermore, an air inlet pipe 6 is fixedly connected to the first end plate 2. The air inlet pipe 6 is an L-shaped pipe, and the material of the air inlet pipe 6 is the same as that of the connecting pipe 1. A valve 7 is provided on the air inlet pipe 6.

[0023] By setting up the inlet pipe 6, a carrier gas can be introduced into the connecting pipe 1. Helium or nitrogen can be used as the carrier gas. The carrier gas is used to prevent the inner wall of the chromatographic column from contacting the air, thereby protecting the chromatographic column.

[0024] Furthermore, a sealing cap is threaded onto the externally threaded pipe 4. The first end plate 2 also has a second threaded hole 8. A plug is also included, which is threaded into either the first threaded hole 5 or the second threaded hole 8. Both the sealing cap and the plug are conventional structures and are not shown in the figure.

[0025] The method of using this utility model is as follows: When the chromatographic column is not in use, connect the carrier gas to the inlet pipe 6, open the valve 7, and the carrier gas enters the connecting pipe 1 through the inlet pipe 6. Air is discharged from the connecting pipe 1 through the external threaded pipe 4, the first threaded hole 5, and the second threaded hole 8. Connect the mass spectrometer end of the chromatographic column to the external threaded pipe 4 and thread the hollow nut on the mass spectrometer end to the external threaded pipe 4. Connect the injection end of the chromatographic column to the first threaded hole 5 and thread the hollow screw on the injection end to the first threaded hole 5. After the carrier gas has been continuously introduced for a certain period of time and the chromatographic column and the connecting pipe 1 are completely filled with carrier gas, close the valve 7, unload the carrier gas, and then use a plug to seal the second threaded hole 8.

[0026] If hollow screws are installed at both ends of the chromatographic column, insert the two ends into the first threaded hole 5 and the second threaded hole 8 respectively, thread the hollow screws into the first threaded hole 5 and the second threaded hole 8 respectively, and then seal the external threaded tube 4 with a sealing cap after introducing the carrier gas.

[0027] This invention can effectively protect the chromatographic column without replacing the graphite pad or VESP pad, without cutting the column, and without affecting the separation effect of the chromatographic column.

[0028] The above description, based on the embodiments shown in the drawings, details the structure, features, and effects of this utility model. The above description is only a preferred embodiment of this utility model, but the scope of implementation of this utility model is not limited to what is shown in the drawings. Any changes made in accordance with the concept of this utility model, or modifications to equivalent embodiments, that do not exceed the spirit covered by the specification and drawings, shall be within the protection scope of this utility model.

Claims

1. A chromatographic column protection device, characterized by: It includes a connecting pipe (1), one end of which has a first end plate (2) and the other end of which has a second end plate (3). The first end plate (2) is provided with an external threaded pipe (4), and the second end plate (3) is provided with a first threaded hole (5).

2. The chromatography column protector of claim 1, wherein: The connecting pipe (1) is a copper pipe or a steel pipe, and the first end plate (2) and the second end plate (3) are made of the same material as the connecting pipe (1).

3. The column protection apparatus of claim 1 or 2, wherein: The inner diameter of the connecting pipe (1) is 2cm-5cm, and the length of the connecting pipe (1) is 15cm-20cm.

4. The column protection apparatus of claim 3, wherein: An air inlet pipe (6) is fixedly connected to the first end plate (2). The air inlet pipe (6) is an L-shaped pipe. The material of the air inlet pipe (6) is the same as that of the connecting pipe (1). A valve (7) is provided on the air inlet pipe (6).

5. The column protection apparatus of claim 4, wherein: The external threaded pipe (4) is threaded with a sealing cap.

6. The column protection apparatus of claim 4, wherein: The first end plate (2) is also provided with a second threaded hole (8).

7. The chromatography column protector of claim 6, wherein: It also includes a plug, which is threadedly connected to the first threaded hole (5) or the second threaded hole (8).

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