Immune cell storage gradient cooling device with rapid taking and placing structure

Abstract

The utility model discloses an immune cell storage gradient cooling device with a quick pick-and-place structure, which comprises a programmed cooling device, the bottom of the programmed cooling device is provided with a bearing plate through a second bearing spring, a test tube rack is arranged above the bearing plate, the top of the test tube rack is provided with test tube grooves at equal intervals, and the test tube grooves are connected with the programmed cooling device. A test tube body is arranged in the test tube groove, an open groove is formed in the top end of the programmed cooling device at the test tube body, a support is fixed at the top end of the programmed cooling device at one side of the open groove, and a sealing gland is arranged at the top of the open groove. According to the utility model, a pop-up pick-and-place structure is adopted, the pick-and-place action of the test tube body can be quickly completed without taking out the test tube rack, and a single test tube body can be taken and placed, so that the interference on the low-temperature preservation effect of other test tube bodies is reduced.

Description

Technical Field

[0001] This utility model relates to the field of immune cell storage technology, specifically to an immune cell storage gradient cooling device with a rapid pick-and-place structure. Background Technology

[0002] Immune cells refer to cells that participate in or are related to the immune response. These include lymphocytes, dendritic cells, monocytes / macrophages, granulocytes, and mast cells. Immune cells need to be preserved in a low-temperature environment. Studies have shown that the preservation effect of biological samples at low temperatures is generally affected by two independent factors: firstly, damage caused by intracellular ice, which is related to the cooling rate (the faster the rate, the greater the damage); and secondly, solute damage. If the cooling rate is too slow, the cells are exposed to high-solute solutions for a longer period, resulting in greater damage. Programmed cooling systems, as commonly used process equipment in the life sciences and biopharmaceutical industries, provide gradient "slow-controlled" cooling conditions for the cryopreservation and dormancy of stem cells, blood cells, and adipocytes.

[0003] Chinese patent CN215649007U discloses an immune cell storage gradient cooling device, including a box, a first hinge shaft, a cooler, a fan, and a door panel. The cooler is installed at the top of the box, and the fan is installed at the bottom of the cooler. Slide rails are installed on both sides of the box, and sliders are installed inside the slide rails. A third hinge shaft is installed on one side wall of the slider, and a buckle is hinged to the outer wall of the third hinge shaft. A test tube rack is installed on the side of the slider away from the slide rail, and test tube slots are evenly spaced inside the test tube rack. Magnetic strips are installed on the side walls of the box and the door panel.

[0004] The aforementioned gradient cooling device connects the test tube rack and the first hinge shaft into a single unit via an mounting block. When medical personnel place test tubes into the test tube slots of the test tube rack, the buckles and straps at one end of the first and second arc-shaped clamps are engaged to secure the test tubes in the slots. However, this method of securing the test tubes requires removing the test tube rack first and then removing the test tubes, which is quite cumbersome. Furthermore, removing a single test tube requires removing the entire test tube rack, which can interfere with the low-temperature preservation of other test tubes. Therefore, we propose an immune cell storage gradient cooling device with a rapid retrieval and placement structure. Utility Model Content

[0005] The purpose of this invention is to provide an immune cell storage gradient cooling device with a rapid pick-and-place structure to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: an immune cell storage gradient cooling device with a rapid pick-and-place structure, comprising a programmed cooling device, a sealing door installed on the outer wall of one side of the programmed cooling device, a support plate installed at the bottom of the programmed cooling device via a second support spring, a test tube rack arranged above the support plate, and test tube slots arranged at equal intervals at the top of the test tube rack, a support block installed at the bottom of the test tube slot via a first support spring, a test tube body arranged inside the test tube slot, an opening slot provided at the top of the programmed cooling device at the position of the test tube body, a support fixed at the top of the programmed cooling device on one side of the opening slot, a sealing cap provided at the top of the opening slot, a positioning seat fixed at the top of the programmed cooling device on the other side of the opening slot, and a through groove arranged inside the positioning seat, a locking rod installed inside the through groove via a spring cylinder, and a locking block fixed at one end of the locking rod, and stops fixed on the two inner walls of the programmed cooling device above the test tube rack.

[0007] Preferably, a limiting sleeve is fixed to the top of the test tube rack outside the test tube body, and the limiting sleeve has a ring structure.

[0008] Preferably, the sealing cap is tightly engaged with the opening groove, and one end of the sealing cap is connected to the support via a rotating shaft, and a torsion spring is installed between the rotating shaft and the support.

[0009] Preferably, the bottom end of the stop is provided with a limiting groove, and the top of the test tube rack at the position of the limiting groove is fixed with a limiting block, which engages with the limiting groove.

[0010] Preferably, the locking block has a sloping trapezoidal structure, and the locking block fits tightly with the sealing cover.

[0011] Preferably, the locking rod has an L-shaped structure, and the end of the locking rod away from the locking block extends to one side of the positioning seat.

[0012] Preferably, the top of the test tube extends into the interior of the opening groove and fits tightly against the sealing cap.

[0013] Preferably, six sets of test tube bodies and opening slots are provided, and the inner diameter of the opening slots is larger than the diameter of the test tube body.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] When it is necessary to pick up or put down a test tube, pull the locking rod to one side to overcome the elasticity of the spring cylinder and move the locking block into the through groove. The locking block releases the sealing cap, which rotates upward around the axis under the elastic action of the torsion spring, opening the slot. At the same time, the sealing cap releases the test tube, and the support block pushes the test tube upward through the first support spring, popping the test tube out of the slot. This allows for quick picking up and putting down of the test tube. After picking up or putting down, flip the sealing cap and press it into the slot. One end of the sealing cap squeezes the locking block and passes over it. The locking block is locked on the surface of the sealing cap, limiting its position. The sealing cap seals the slot. This device adopts a pop-up picking and putting structure, which can quickly complete the picking and putting down of test tubes without removing the test tube rack. Moreover, it can pick up and put down a single test tube, reducing interference with the low-temperature preservation effect of other test tubes. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the main structure of this utility model;

[0017] Figure 2 For the present utility model Figure 1 Enlarged structural diagram at point A in the middle;

[0018] Figure 3 This is a schematic diagram of the structure of the present invention in the picking and placing state;

[0019] Figure 4 This is a top view of the structure of this utility model;

[0020] Figure 5 This is a schematic diagram of the appearance structure of this utility model.

[0021] In the diagram: 1. Programmable cooling device; 2. Support plate; 3. Test tube rack; 4. Test tube trough; 401. First support spring; 402. Support block; 5. Limiting sleeve; 6. Test tube body; 7. Opening groove; 8. Sealing cap; 9. Stop block; 10. Limiting slot; 11. Limiting block; 12. Second support spring; 13. Positioning seat; 14. Through groove; 15. Locking rod; 16. Spring cylinder; 17. Locking block; 18. Support; 19. Rotating shaft; 20. Torsion spring; 21. Sealing door. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the scope of protection of the present utility model.

[0023] Please see Figure 1-5An embodiment of this utility model is provided: an immune cell storage gradient cooling device with a rapid pick-and-place structure, including a programmed cooling device 1, a sealing door 21 installed on the outer wall of one side of the programmed cooling device 1, a support plate 2 installed at the bottom of the programmed cooling device 1 by a second support spring 12, a test tube rack 3 provided above the support plate 2, and a test tube groove 4 with equal spacing provided at the top of the test tube rack 3, a support block 402 installed at the bottom of the test tube groove 4 by a first support spring 401, and a test tube body 6 provided inside the test tube groove 4;

[0024] Specifically, place the test tube body 6 in the test tube slot 4 at the top of the test tube rack 3, place the test tube rack 3 on the support plate 2, and press down on the test tube rack 3 so that the support plate 2 squeezes the second support spring 12 and moves it down, pushing the test tube rack 3 into the program cooling device 1. Release the test tube rack 3 so that it is locked under the stop block 9 under the elastic action of the second support spring 12. The limiting block 11 at the top of the test tube rack 3 is locked into the limiting slot 10 at the bottom of the stop block 9 to position the test tube rack 3. The top of the test tube body 6 extends into the corresponding opening slot 7 and abuts against the sealing cap 8. The test tube rack 3 together with the test tube body 6 can then be placed into the program cooling device 1. Then close the sealing door 21.

[0025] The top of the programmed cooling device 1 at the position of test tube body 6 is provided with an opening groove 7. A support 18 is fixed to the top of the programmed cooling device 1 on one side of the opening groove 7. A sealing cap 8 is provided at the top of the opening groove 7. A positioning seat 13 is fixed to the top of the programmed cooling device 1 on the other side of the opening groove 7. A through groove 14 is provided inside the positioning seat 13. A locking rod 15 is installed inside the through groove 14 through a spring cylinder 16. A locking block 17 is fixed to one end of the locking rod 15. Blocks 9 are fixed on the two inner walls of the programmed cooling device 1 above the test tube rack 3.

[0026] Specifically, when it is necessary to pick up or put down the test tube 6, pull the locking rod 15 to one side to overcome the elasticity of the spring cylinder 16 and move the locking block 17 into the through groove 14. The locking block 17 releases the sealing cap 8. Under the elastic action of the torsion spring 20, the sealing cap 8 flips upward around the rotating shaft 19, causing the opening groove 7 to open. At the same time, the sealing cap 8 releases the test tube 6, and the support block 402 pushes the test tube 6 upward through the first support spring 401, popping the test tube 6 out of the opening groove 7. (See attached diagram) Figure 3 This allows for quick handling of test tube 6;

[0027] After taking out and placing, flip the sealing cap 8 and press it into the opening groove 7. One end of the sealing cap 8 squeezes the locking block 17 and passes over the locking block 17. The locking block 17 is stuck on the surface of the sealing cap 8 to limit the sealing cap 8. The sealing cap 8 seals the opening groove 7. The device adopts a pop-up taking out and placing structure, which can quickly complete the taking out and placing of test tubes 6 without removing the test tube rack 3. Moreover, it can take out and place a single test tube 6, reducing interference with the low temperature preservation effect of other test tubes 6.

[0028] A limiting sleeve 5 is fixed at the top of the test tube rack 3 on the outside of the test tube body 6, and the limiting sleeve 5 has a ring structure.

[0029] The sealing cap 8 is tightly engaged with the opening groove 7, and one end of the sealing cap 8 is connected to the support 18 via the rotating shaft 19, and a torsion spring 20 is installed between the rotating shaft 19 and the support 18.

[0030] The bottom end of the stop block 9 is provided with a limiting slot 10, and the top of the test tube rack 3 at the position of the limiting slot 10 is fixed with a limiting block 11, which is engaged with the limiting slot 10.

[0031] The locking block 17 has a sloping trapezoidal structure and is tightly fitted with the sealing cover 8;

[0032] The locking rod 15 has an L-shaped structure, and the end of the locking rod 15 away from the locking block 17 extends to one side of the positioning seat 13;

[0033] When it is necessary to remove the test tube rack 3 and the test tube body 6 as a whole, open the sealing door 21, press down on the test tube rack 3 to move the test tube body 6 below the opening groove 7, the limiting block 11 at the top of the test tube rack 3 separates from the limiting groove 10, and then the test tube rack 3 can be pulled out.

[0034] The top of the test tube body 6 extends into the interior of the opening groove 7 and fits tightly against the sealing cap 8;

[0035] There are six sets of test tube bodies 6 and opening grooves 7, and the inner diameter of the opening grooves 7 is larger than the diameter of the test tube body 6.

[0036] In this embodiment, the following steps are taken: First, place the test tube body 6 in the test tube slot 4 at the top of the test tube rack 3. Place the test tube rack 3 on the support plate 2 and press down on the test tube rack 3 so that the support plate 2 compresses the second support spring 12 and moves it downward, pushing the test tube rack 3 into the programmable cooling device 1. Release the test tube rack 3 so that it is locked under the stop block 9 under the elastic action of the second support spring 12. The limiting block 11 at the top of the test tube rack 3 is locked into the limiting slot 10 at the bottom of the stop block 9 to position the test tube rack 3. The top of the test tube body 6 extends into the corresponding opening slot 7 and abuts against the sealing cap 8, thus allowing the test tube to be cooled. The test tube rack 3, along with the test tube 6, is placed into the programmed cooling device 1, and then the sealing door 21 is closed. When it is necessary to remove or place the test tube 6, the locking rod 15 is pulled to one side to overcome the elasticity of the spring cylinder 16 and move the locking block 17 into the through groove 14. The locking block 17 releases the sealing cap 8, which, under the elastic action of the torsion spring 20, rotates upward around the pivot 19, opening the opening groove 7. Simultaneously, the sealing cap 8 releases the test tube 6, and the support block 402 pushes the test tube 6 upward via the first support spring 401, ejecting the test tube 6 from the opening groove 7. (See attached diagram.) Figure 3 This allows for quick placement and removal of test tubes 6. After placement, the sealing cap 8 is flipped over and pressed into the opening groove 7. One end of the sealing cap 8 presses against the locking block 17 and passes over the locking block 17. The locking block 17 is locked on the surface of the sealing cap 8, limiting the sealing cap 8. The sealing cap 8 seals the opening groove 7. This device adopts a pop-up placement and removal structure, which can quickly complete the placement and removal of test tubes 6 without removing the test tube rack 3. Moreover, it can place and remove individual test tubes 6, reducing interference with the low-temperature preservation effect of other test tubes 6. When it is necessary to remove the test tube rack 3 and test tubes 6 as a whole, the sealing door 21 is opened, and the test tube rack 3 is pressed down to move the test tubes 6 below the opening groove 7. The limiting block 11 at the top of the test tube rack 3 separates from the limiting groove 10, and then the test tube rack 3 can be pulled out.

[0037] Obviously, the embodiments described above are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort should fall within the protection scope of this utility model.

Claims

1. An immune cell storage gradient cooling device with a rapid pick-and-place structure, comprising a programmed cooling device (1), wherein a sealing door (21) is installed on the outer wall of one side of the programmed cooling device (1), characterized in that, The bottom of the programmed cooling device (1) is supported by a support plate (2) via a second support spring (12). A test tube rack (3) is provided above the support plate (2), and the top of the test tube rack (3) is provided with equally spaced test tube slots (4). A support block (402) is installed at the bottom of the test tube slots (4) via a first support spring (401). A test tube body (6) is provided inside the test tube slot (4). An opening slot (7) is provided at the top of the programmed cooling device (1) at the position of the test tube body (6). The programmable cooling device (1) on one side of the opening slot (7) has a process... The top of the cooling device (1) is fixed with a support (18), the top of the opening slot (7) is provided with a sealing cap (8), the top of the cooling device (1) on the other side of the opening slot (7) is fixed with a positioning seat (13), and the inside of the positioning seat (13) is provided with a through slot (14). The inside of the through slot (14) is installed with a locking rod (15) through a spring cylinder (16), and one end of the locking rod (15) is fixed with a locking block (17). The two inner walls of the cooling device (1) above the test tube rack (3) are fixed with blocks (9).

2. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The test tube rack (3) on the outside of the test tube body (6) is fixed with a limiting sleeve (5), and the limiting sleeve (5) is a ring structure.

3. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The sealing cap (8) is tightly engaged with the opening groove (7), and one end of the sealing cap (8) is connected to the support (18) through a rotating shaft (19), and a torsion spring (20) is installed between the rotating shaft (19) and the support (18).

4. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The bottom end of the stop block (9) is provided with a limiting slot (10), and the top of the test tube rack (3) at the position of the limiting slot (10) is fixed with a limiting block (11), and the limiting block (11) is engaged with the limiting slot (10).

5. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The locking block (17) has a sloping trapezoidal structure, and the locking block (17) is tightly fitted with the sealing cover (8).

6. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The locking rod (15) has an L-shaped structure, and the end of the locking rod (15) away from the locking block (17) extends to one side of the positioning seat (13).

7. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The top of the test tube body (6) extends into the interior of the opening groove (7) and fits tightly against the sealing cap (8).

8. The immune cell storage gradient cooling device with a rapid pick-and-place structure according to claim 1, characterized in that: The test tube body (6) and the opening groove (7) are provided in six sets, and the inner diameter of the opening groove (7) is larger than the diameter of the test tube body (6).

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