A multi-channel enzyme marker

Abstract

The utility model provides a kind of multichannel enzyme label appearance, it is related to medical examination instrument technical field, including enzyme label appearance body, the inside of enzyme label appearance body is equipped with working cavity, the inner wall of working cavity is slidably connected with the carrier frame for placing enzyme label plate by slide rail, the inside of working cavity is provided with pusher assembly, pusher assembly is set, by rotating rotating block, rotating block drives driving gear to rotate, driving gear drives two groups of driven gear to rotate, can make two groups of driven gear synchronous rotation, and further drive the rotation of the top block on the surface of connecting rod, make the top plate rise, avoid uneven stress of top plate to cause jamp or deviation in jacking process, while the oval top block on connecting rod jacks top plate, form smooth wave type propulsion action, avoid instantaneous impact force to the damage of enzyme label plate, can improve the service life of component to some extent, reduce maintenance cost.

Description

Technical Field

[0001] This utility model relates to the field of medical testing instrument technology, and in particular to a multi-channel enzyme-linked immunosorbent assay (ELISA) reader. Background Technology

[0002] An ELISA reader is a specialized instrument for reading and analyzing the results of enzyme-linked immunosorbent assay (ELISA) experiments. ELISA reactions involve an enzyme coupled to an antigen or antibody catalyzing a chromogenic substrate. The reaction result is displayed as a color, and the concentration of the antibody or antigen in the sample can be determined by the intensity of the color, i.e., the absorbance value. ELISA readers are widely used in clinical testing, biological research, agricultural science, and food and environmental science.

[0003] Chinese Patent Publication No. CN219046101U discloses a multi-channel ELISA reader, including an ELISA reader body, a pressing assembly, and a feeding assembly. The ELISA reader body has a working chamber inside. A carrier frame for placing ELISA plates is slidably connected to the bottom inner wall of the working chamber via a slide rail. The pressing assembly includes four slide rods fixedly connected to the top inner wall of the working chamber, a pressing frame slidably connected to the four slide rods, a pressing rod provided on the bottom inner wall of the pressing frame, and a spring sleeved on the slide rods. The two ends of the spring are respectively connected to the top inner wall of the working chamber and the pressing frame. The feeding assembly includes a casing connected to the outside of the ELISA reader body, a top plate provided inside the casing, a rotating rod rotatably connected inside the casing, and a cam sleeved on the rotating rod.

[0004] In this existing design, although the enzyme-labeled plate can be fixed in the working chamber by the pressing component to prevent the plate from shaking when subjected to external force, and the cam can drive the top plate to move upward, so that the top plate can lift the enzyme-labeled plate from the carrier holder for easy handling, the device only has a single set of cams. When in contact with the top plate, uneven lifting force and jamming are likely to occur, which affects the smooth lifting of the top plate and may also cause excessive wear of the components, affecting the service life of the components.

[0005] Therefore, a multi-channel microplate reader was designed to solve the above problems. Utility Model Content

[0006] To address the problems mentioned in the background art, this utility model provides a multi-channel ELISA reader, which features more uniform power transmission to the top block and reduced mechanical wear.

[0007] This utility model adopts the following technical solution: a multi-channel ELISA reader, including an ELISA reader body, an internal working chamber, a carrier frame for placing ELISA plates slidably connected to the inner wall of the working chamber via a slide rail, a material pushing assembly inside the working chamber, the material pushing assembly including a box, a rotating rod, a driving gear, a driven gear, a connecting rod, a top block, and a top plate, the box being mounted on the outside of the ELISA reader body, the rotating rod being rotatably connected to the side of the box, the driving gear being fixedly mounted at one end of the rotating rod, the rotating block being fixedly mounted at the other end of the rotating rod, the driven gear being rotatably connected to the inner wall of the box, the connecting rod being fixedly mounted to the side of the driven gear, the top block being fixedly mounted to the surface of the connecting rod, and the top plate being slidably connected to the inner wall of the box via a limiting groove.

[0008] In a preferred embodiment of this multichannel ELISA reader, the housing is positioned below the carrier holder.

[0009] In a preferred embodiment of the multi-channel ELISA reader of this invention, the drive gear is mounted on the inner wall of the housing, and the rotating block is mounted on the outer surface of the housing.

[0010] In a preferred embodiment of the multi-channel ELISA reader of this invention, there are two sets of driven gears, which are symmetrically mounted on both sides of the driving gear.

[0011] In a preferred embodiment of the multi-channel ELISA reader of this invention, both sets of driven gears are meshed with the driving gear.

[0012] In a preferred embodiment of the multichannel ELISA reader of this invention, the connecting rod and the inner wall of the housing are rotatably connected by a bearing.

[0013] In a preferred embodiment of the multi-channel ELISA reader of this invention, the top block is elliptical in shape, and there are several groups of top blocks, with the axis of each group of top blocks being the same as the axis of the connecting rod.

[0014] As a preferred embodiment of the multi-channel ELISA reader of this invention, the rotating block has a sliding cavity inside, a counterweight is movably installed inside the sliding cavity, a guide groove is provided on the side of the box, and a guide block is fixedly installed on the inner wall of the rotating block.

[0015] In a preferred embodiment of this multichannel ELISA reader, the guide groove is arc-shaped, and the guide block is slidably connected to the interior of the guide groove.

[0016] Compared with the prior art, the advantages and positive effects of this utility model are as follows: A pushing component is provided. By rotating the rotating block, the rotating block drives the driving gear to rotate, which in turn drives two sets of driven gears to rotate synchronously. This, in turn, drives the top block on the surface of the connecting rod to rotate, causing the top plate to rise. This avoids uneven force on the top plate, which could lead to jamming or deviation during the lifting process. Simultaneously, the elliptical top block on the connecting rod lifts the top plate, forming a smooth, wave-like pushing motion, avoiding damage to the enzyme-labeled plate from instantaneous impact. This can improve the service life of the components to a certain extent and reduce maintenance costs. Furthermore, guide blocks and guide grooves are provided to limit the movement trajectory of the rotating block. A counterweight is also installed inside the rotating block, allowing it to automatically reset, thus improving work efficiency. Attached Figure Description

[0017] Figure 1 A schematic diagram of a multi-channel ELISA reader is provided for this utility model;

[0018] Figure 2 A partial schematic diagram of a multichannel ELISA reader is provided for this utility model;

[0019] Figure 3 A schematic diagram of a multi-channel microplate reader carrier holder is provided for this utility model;

[0020] Figure 4 A partial exploded view of the feeding assembly of a multi-channel ELISA reader is provided for this utility model;

[0021] Figure 5 A schematic diagram of a multi-channel microplate reader feeding assembly is provided for this utility model;

[0022] Figure 6 This invention proposes a multi-channel ELISA reader. Figure 5 Enlarged view of point A in the middle.

[0023] Legend:

[0024] 1. Microplate reader body; 2. Working chamber; 3. Slide rail; 4. Carrier holder; 5. Pushing assembly; 501. Box body; 502. Rotating rod; 503. Driving gear; 504. Driven gear; 505. Connecting rod; 506. Top block; 507. Top plate; 508. Rotating block; 509. Limiting groove; 6. Slide cavity; 7. Counterweight; 8. Guide groove; 9. Guide block. Detailed Implementation

[0025] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0026] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0027] Example 1

[0028] In existing technologies, existing multi-channel ELISA readers include an ELISA reader body, a pressing assembly, and a pushing assembly. The ELISA reader body has a working chamber inside, and a carrier frame for placing ELISA plates is slidably connected to the bottom inner wall of the working chamber via slide rails. The pressing assembly includes four slide rods fixedly connected to the top inner wall of the working chamber, a pressing frame slidably connected to the four slide rods, a pressing rod located on the bottom inner wall of the pressing frame, and a spring sleeved on the slide rods. The two ends of the spring are respectively connected to the top inner wall of the working chamber and the pressing frame. The pushing assembly includes a casing connected to the outside of the ELISA reader body, a top plate located inside the casing, a rotating rod rotatably connected inside the casing, and a cam sleeved on the rotating rod. The pressing assembly fixes the ELISA plates entering the working chamber, preventing the ELISA plates from shaking when subjected to external forces. Furthermore, the cam drives the top plate to move upward, allowing the top plate to lift the ELISA plates from the carrier frame for easy removal.

[0029] This application incorporates the aforementioned prior art, such as Figures 1 to 6 As shown, this utility model provides a technical solution: a multi-channel ELISA reader, including an ELISA reader body 1, with a working chamber 2 inside the ELISA reader body 1. A carrier frame 4 for placing ELISA plates is slidably connected to the inner wall of the working chamber 2 via a slide rail 3. A pusher assembly 5 is provided inside the working chamber 2, and the pusher assembly 5 includes a housing 501, a rotating rod 502, a driving gear 503, a driven gear 504, a connecting rod 505, a top block 506, and a top plate 507. The ELISA reader body 1 is located outside... A box body 501 is mounted on the side, and a rotating rod 502 is rotatably connected to the side of the box body 501. A drive gear 503 is fixedly mounted at one end of the rotating rod 502, and a rotating block 508 is fixedly mounted at the other end of the rotating rod 503. A driven gear 504 is rotatably connected to the inner wall of the box body 501. A connecting rod 505 is fixedly mounted on the side of the driven gear 504, and a top block 506 is fixedly mounted on the surface of the connecting rod 505. A top plate 507 is slidably connected to the inner wall of the box body 501 through a limiting groove 509.

[0030] In this implementation scheme, a pusher assembly 5 is provided. By rotating the rotating block 508, the rotating block 508 drives the rotating rod 502 to rotate, which in turn drives the drive gear 503 inside the box 501 to rotate. Since the drive gear 503 and the driven gear 504 are meshed, the drive gear 503 drives the driven gear 504 to rotate, which allows the two sets of driven gears 504 to rotate synchronously. This, in turn, drives the top block 506 on the surface of the connecting rod 505 to rotate, causing the top plate 507 to rise. This avoids uneven force on the top plate 507, which could cause jamming or deviation during the lifting process. At the same time, the elliptical top block 506 on the connecting rod 505 lifts the top plate 507, forming a smooth wave-like pushing action. This avoids damage to the enzyme-labeled plate from instantaneous impact forces, which can improve the service life of the components and reduce maintenance costs to a certain extent.

[0031] Combining the above solutions:

[0032] Furthermore:

[0033] like Figure 1 As shown;

[0034] To facilitate the fixation of the ELISA plate, in an optional embodiment, the housing 501 is positioned below the carrier holder 4.

[0035] In this embodiment: the enzyme label plate is fixed inside the carrier frame 4, and the box body 501 is located below the carrier frame 4. When it is necessary to remove the enzyme label plate, the rotating block 508 can be rotated so that the top block 506 can lift the top plate 507, thereby pushing the enzyme label plate out of the carrier frame 4, making it easy to pick up the enzyme label plate.

[0036] Combining the above solutions:

[0037] Furthermore:

[0038] like Figures 4 to 6 As shown;

[0039] To facilitate the rotation of the rotating rod 502, in an optional embodiment, the drive gear 503 is mounted on the inner wall of the housing 501, and the rotating block 508 is mounted on the outer surface of the housing 501.

[0040] In this embodiment: a drive gear 503 is installed at one end of the rotating rod 502, and a rotating block 508 is installed at the other end of the rotating rod 502. The drive gear 503 is installed on the inner wall of the box 501, and the rotating block 508 is installed on the outer surface of the box 501. This allows the rotating rod 502 to rotate by rotating the rotating block 508 outside the box 501, thereby driving the drive gear 503 to rotate.

[0041] Combining the above solutions:

[0042] Furthermore:

[0043] like Figure 4 As shown;

[0044] To improve practicality, in an optional embodiment, there are two sets of driven gears 504, which are symmetrically mounted on both sides of the driving gear 503.

[0045] In this embodiment, the synchronous rotation of the two sets of driven gears 504 makes the force exerted by the top block 506 on the top plate 507 symmetrically distributed, forming a balanced wave-like lifting action, which avoids lateral displacement of the enzyme-labeled plate during vertical movement, and also avoids gear wear or bearing damage caused by uneven force.

[0046] Combining the above solutions:

[0047] Furthermore:

[0048] like Figure 4 As shown;

[0049] In an optional embodiment, both sets of driven gears 504 are meshed with the driving gear 503 in order to drive the driven gear 504 to rotate.

[0050] In this embodiment: when the rotating block 508 is rotated, the rotating block 508 can drive the rotating rod 502 to rotate, and the rotating rod 502 can drive the driving gear 503 to rotate. Since both sets of driven gears 504 are meshed with the driving gear 503, the driving gear 503 can drive the two sets of driven gears 504 to rotate synchronously.

[0051] Combining the above solutions:

[0052] Furthermore:

[0053] like Figure 4 As shown;

[0054] To facilitate the rotation of the connecting rod 505, in an optional embodiment, the connecting rod 505 and the inner wall of the housing 501 are rotatably connected by a bearing.

[0055] In this embodiment, the connecting rod 505 and the inner wall of the box 501 are rotatably connected by a bearing. The low friction characteristics of the bearing make the connecting rod 505 rotate more smoothly, reduce energy loss in the power transmission process, and make the lifting action of the top block 506 on the top plate 507 more stable and uniform.

[0056] Combining the above solutions:

[0057] Furthermore:

[0058] like Figure 4 As shown;

[0059] To prevent the top plate 507 from tilting, in an optional embodiment, the top block 506 is elliptical in shape, and there are several groups of top blocks 506, with the axis of each group of top blocks 506 being the same as the axis of the connecting rod 505.

[0060] In this embodiment: by having multiple sets of top blocks 506 rotate synchronously with the connecting rod 505, the force points at the bottom of the top plate 507 are increased, so that the top plate 507 moves upward smoothly and avoids tilting of the top plate 507.

[0061] Combining the above solutions:

[0062] Furthermore:

[0063] like Figures 5 to 6 As shown;

[0064] In an optional embodiment, to enable the rotating block 508 to automatically reset, a sliding cavity 6 is provided inside the rotating block 508, a counterweight 7 is movably installed inside the sliding cavity 6, a guide groove 8 is provided on the side of the box body 501, and a guide block 9 is fixedly installed on the inner wall of the rotating block 508.

[0065] In this embodiment: a counterweight 7 is set inside the rotating block 508. When the rotating block 508 is rotated, the rotating block 508 can drive the top plate 507 to push out the enzyme-labeled plate. After the enzyme-labeled plate is removed, the rotating block 508 is released, and the rotating block 508 can automatically reset under the action of the counterweight 7's own gravity, which improves work efficiency.

[0066] Combining the above solutions:

[0067] Furthermore:

[0068] like Figures 5 to 6 As shown;

[0069] In order to limit the movement trajectory of the rotating block 508, in an optional embodiment, the guide groove 8 is arc-shaped, and the guide block 9 is slidably connected inside the guide groove 8.

[0070] In this embodiment, guide block 9 and guide groove 8 are provided to limit the movement trajectory of rotating block 508, prevent excessive rotation of rotating block 508, and improve the reset efficiency of rotating block 508.

[0071] Working principle: In use, first place the ELISA plate into the placement opening on the carrier holder 4, then push the carrier holder 4 into the working chamber 2. When it is necessary to remove the ELISA plate, pull the carrier holder 4 outward. The carrier holder 4 moves the ELISA plate to the top of the box 501. By rotating the rotating block 508, the rotating block 508 drives the rotating rod 502 to rotate. At the same time, the rotating block 508 drives the guide block 9 to slide in the guide groove 8. When the rotating rod 502 rotates, it drives the driving gear 503 to rotate. The driving gear 503 then drives the driven gear 504 to rotate. The driven gear 504 then drives the connecting rod 505 to rotate. The connecting rod 505 can drive the top block 506 to rotate and move the top plate 501. 07 is lifted upwards, and the ELISA plate is lifted upwards by the top plate 507 for easy removal. After the ELISA plate is removed, the rotating block 508 is released. Due to its own gravity, the counterweight 7 inside the rotating block 508 slides in the sliding cavity 6, thereby driving the rotating block 508 to rotate in the opposite direction. The rotating block 508 then drives the guide block 9 to rotate in the opposite direction in the guide groove 8. At the same time, the rotating block 508 drives the rotating rod 502 to rotate in the opposite direction. At this time, the rotating rod 502 can drive the driving gear 503 to rotate in the opposite direction. The driving gear 503 drives the driven gear 504 to rotate in the opposite direction, which in turn drives the connecting rod 505 to rotate. The connecting rod 505 can then drive the top block 506 to reset.

[0072] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A multi-channel ELISA reader, comprising an ELISA reader body (1), characterized in that: The microplate reader body (1) has a working chamber (2) inside. A carrier rack (4) for placing microplates is slidably connected to the inner wall of the working chamber (2) via a slide rail (3). A feeding assembly (5) is provided inside the working chamber (2). The feeding assembly (5) includes a box body (501), a rotating rod (502), a driving gear (503), a driven gear (504), a connecting rod (505), a top block (506), and a top plate (507). A box body (501) is installed on the outside of the microplate reader body (1). A rotating rod (502) is rotatably connected to the side of the box (501). A drive gear (503) is fixedly installed at one end of the rotating rod (502), and a rotating block (508) is fixedly installed at the other end of the rotating rod (502). A driven gear (504) is rotatably connected to the inner wall of the box (501). A connecting rod (505) is fixedly installed on the side of the driven gear (504), and a top block (506) is fixedly installed on the surface of the connecting rod (505). A top plate (507) is slidably connected to the inner wall of the box (501) through a limiting groove (509).

2. The multi-channel ELISA reader according to claim 1, characterized in that: The box (501) is located below the carrier frame (4).

3. The multi-channel ELISA reader according to claim 2, characterized in that: The drive gear (503) is mounted on the inner wall of the housing (501), and the rotating block (508) is mounted on the outer surface of the housing (501).

4. The multi-channel microplate reader according to claim 3, characterized in that: There are two sets of driven gears (504), and the two sets of driven gears (504) are symmetrically installed on both sides of the driving gear (503).

5. The multichannel microplate reader according to claim 4, characterized in that: Both sets of driven gears (504) are meshed with the driving gear (503).

6. The multichannel microplate reader according to claim 5, characterized in that: The connecting rod (505) and the inner wall of the box (501) are rotatably connected by bearings.

7. The multichannel microplate reader according to claim 6, characterized in that: The top block (506) is elliptical in shape, and there are several groups of top blocks (506). The axis of each group of top blocks (506) is the same as the axis of the connecting rod (505).

8. The multichannel microplate reader according to claim 7, characterized in that: The rotating block (508) has a sliding cavity (6) inside, and a counterweight (7) is movably installed inside the sliding cavity (6). The side of the box (501) has a guide groove (8), and a guide block (9) is fixedly installed on the inner wall of the rotating block (508).

9. The multichannel microplate reader according to claim 8, characterized in that: The guide groove (8) is arc-shaped, and the guide block (9) is slidably connected inside the guide groove (8).

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