A safe and precise limulus tissue punch biopsy sampling device

Abstract

This invention belongs to the field of biotoxin detection technology, specifically relating to a safe and accurate horseshoe crab tissue biopsy sampling device. It includes a catheter and a guide tube, with the guide tube located inside the catheter. A handle is fixedly connected to the top of the guide tube, and a through hole communicating with the guide tube is opened at the top of the handle. A hollow tube is fixedly connected to the bottom of the guide tube, communicating with the guide tube. A sampling element is assembled at the bottom of the hollow tube. A guide wire is disposed within the inner cavity of the guide tube, with a flexible upper part and a vertical lower part. A control element is disposed on the handle. The bottom end of the guide wire passes through the hollow tube and connects to the sampling element. An elastic element is disposed on the sidewall of the guide wire located inside the hollow tube. This invention utilizes a catheter design to accurately guide the horseshoe crab tissue, and when used with the sampling element, facilitates accurate extraction of the desired tissue.

Description

Technical Field

[0001] This invention belongs to the field of biotoxin detection technology, specifically relating to a safe and accurate horseshoe crab tissue puncture biopsy sampling device. Background Technology

[0002] Horseshoe crabs themselves do not contain substances that are toxic to humans. However, in order to ensure their safety and effectiveness in scientific research and commercial applications, samples of horseshoe crab blood, exoskeleton, skin, and internal organs are usually taken for testing to confirm whether they meet specific quality standards and to provide data support for subsequent research and development.

[0003] Currently, when sampling the internal organs or tissues of horseshoe crabs, many methods involve directly fixing the horseshoe crab and then cutting it open. While this achieves the sampling purpose, the incisions on the surface of the horseshoe crab are often large, making them prone to infection and death during the healing process. It also makes it difficult to guide the sampling location and reduces the sampling effectiveness. Utility Model Content

[0004] The purpose of this invention is to provide a safe and accurate horseshoe crab tissue puncture biopsy sampling device that can accurately guide the tissue inside the horseshoe crab using a catheter design, and can be used with a sampling device to facilitate accurate extraction of the required tissue from the body.

[0005] The specific technical solution adopted in this utility model is as follows:

[0006] A safe and accurate horseshoe crab tissue biopsy sampling device includes a catheter and a guide tube. The guide tube is located inside the catheter. A handle is fixedly connected to the top of the guide tube. A through hole communicating with the guide tube is opened on the top of the handle. A hollow tube is fixedly connected to the bottom of the guide tube. The hollow tube communicates with the guide tube. A sampling element is assembled at the bottom of the hollow tube. A guide wire is disposed in the inner cavity of the guide tube. The upper part of the guide wire is a flexible part, and the lower part of the guide wire is a vertical part. A control element is disposed on the handle. The bottom end of the guide wire passes through the hollow tube and is connected to the sampling element. An elastic element is disposed on the side wall of the guide wire located inside the hollow tube.

[0007] The sampling device includes a base plate fixedly connected to the bottom end of the guide wire, an annular blade fixedly connected to the top surface of the base plate, a storage cavity opened on the bottom end face of the hollow tube, an annular groove opened on the bottom end face of the hollow tube, the annular blade being adapted to the annular groove, and a conical block assembled on the bottom surface of the base plate.

[0008] The control component includes a groove on the top surface of the handle, a push plate slidably connected in the groove, the other end of the guide wire being fixedly connected to the push plate, and the top surface of the push plate having anti-slip texture.

[0009] The through hole sidewall is fitted with a guide wheel, and the guide wire contacts the guide wheel.

[0010] The guide wire sidewall is fixedly connected to a baffle inside the hollow tube, and a spring is sleeved on the guide wire sidewall. The two ends of the spring are fixedly connected to the baffle and the sidewall of the hollow tube, respectively.

[0011] The conical block is threadedly connected to the base plate.

[0012] The technical effects achieved by this utility model are as follows:

[0013] This practical and safe horseshoe crab tissue puncture biopsy sampling device utilizes the cooperation between the catheter, guide tube, handle, sampling element, and control element to create micropores on the surface of the horseshoe crab according to the sampled tissue, and inserts the catheter for guidance. This facilitates the sampling element to be inserted into the horseshoe crab body with the guide tube for tissue sampling, achieving the purpose of accurate sampling, and minimizing the trauma area on the horseshoe crab surface. Attached Figure Description

[0014] Figure 1 This is a perspective view of this utility model embodiment;

[0015] Figure 2 This is a cross-sectional structural schematic diagram of this utility model embodiment;

[0016] Figure 3 This is a perspective view of the sample taken in this utility model embodiment;

[0017] Figure 4 This is a cross-sectional structural schematic diagram of the sampling component in this utility model embodiment;

[0018] Figure 5 This is a practical embodiment. Figure 2 Enlarged view of point A in the image.

[0019] The attached diagram lists the components represented by each number as follows:

[0020] 1. Conduit; 2. Guide tube; 3. Handle; 4. Hollow tube; 5. Storage cavity; 6. Conical block; 7. Guide wire; 8. Push plate; 9. Groove; 10. Base plate; 11. Annular blade; 12. Annular groove; 13. Baffle; 14. Spring; 15. Guide wheel. Detailed Implementation

[0021] To make the purpose and advantages of this utility model clearer, the following detailed description is provided in conjunction with embodiments. It should be understood that the following text is merely used to describe one or more specific implementations of this utility model and does not strictly limit the scope of protection specifically claimed by this utility model.

[0022] like Figures 1-5As shown, a safe and precise horseshoe crab tissue biopsy sampling device includes a catheter 1 and a guide tube 2. The guide tube 2 is located inside the catheter 1. A handle 3 is fixedly connected to the top of the guide tube 2. A through hole communicating with the guide tube 2 is opened at the top of the handle 3. A hollow tube 4 is fixedly connected to the bottom of the guide tube 2, communicating with the guide tube 2. A sampling element is assembled at the bottom of the hollow tube 4. A guide wire 7 is arranged in the inner cavity of the guide tube 2. The upper part of the guide wire 7 is a flexible part, and the lower part of the guide wire 7 is a vertical part. The flexible part of the guide wire 7 can be made of steel wire, rope, fiber material, etc., and can be bent. The vertical part is made of harder materials such as plastic, metal, composite material, etc., to support the sampling element and ensure that it will not shake in the initial state, thus having high stability. A control element is provided on the handle 3. The bottom end of the guide wire 7 passes through the hollow tube 4 and is connected to the sampling element. An elastic element is arranged on the side wall of the guide wire 7 inside the hollow tube 4.

[0023] like Figure 3 and Figure 4 As shown, the sampling component includes a base plate 10 fixedly connected to the bottom end of the guide wire 7. An annular blade 11 is fixedly connected to the top surface of the base plate 10. A storage cavity 5 is opened on the bottom end face of the hollow tube 4. An annular groove 12 is opened on the bottom end face of the hollow tube 4. The annular blade 11 is adapted to the annular groove 12. A conical block 6 is assembled on the bottom surface of the base plate 10.

[0024] Specifically, because the tissues inside the horseshoe crab are relatively soft, when squeezed by the cone-shaped block 6, the fat, blood and other tissues inside the body enter the inner side of the ring blade 11 through the ring blade 11 for storage. After sampling is completed, the tissues can be controlled by the guide wire 7 to enter the storage cavity 5, avoiding environmental contamination during the retrieval process.

[0025] like Figure 2 and Figure 5 As shown, the control component includes a groove 9 on the top surface of the handle 3, a push plate 8 is slidably connected in the groove 9, the other end of the guide wire 7 is fixedly connected to the push plate 8, and the top surface of the push plate 8 is provided with anti-slip texture.

[0026] The conical block 6 can guide and compress within the horseshoe crab body. Alternatively, spiral blades can be installed on the surface of the conical block 6 according to actual needs, so that the sample can be inserted into the designated position and the tissue at that position can be cut to facilitate sampling.

[0027] like Figure 5 As shown, a guide wheel 15 is fitted on the side wall of the through hole, and the guide wire 7 contacts the guide wheel 15. This can reduce the friction between the guide wire 7 and the handle 3, and when the push plate 8 needs to be pulled, it can achieve the purpose of saving effort and effectively improve its control effect.

[0028] The guide wire 7 has a baffle 13 fixedly connected to the side wall inside the hollow tube 4. A spring 14 is sleeved on the side wall of the guide wire 7, and the two ends of the spring 14 are fixedly connected to the baffle 13 and the side wall of the hollow tube 4, respectively.

[0029] In the initial state, the conical block 6 and the annular blade 11 are located on the lower side of the hollow tube 4, and the annular blade 11 is detached from the annular groove 12. The sampled tissue can easily enter the upper side of the base plate 10 through the gap between the annular blade 11 and the annular groove 12. At the same time, the annular blade 11 can be used to remove the tissue in the body, ensuring the smooth sampling.

[0030] When the push plate 8 is pulled, the spring 14 moves upward through the guide wire 7. The guide wire 7 moves the sampling element upward, which is used to seal the sampled sample in the storage cavity 5 and at the same time facilitates the resetting of the sampling element.

[0031] like Figure 4 As shown, the conical block 6 is threadedly connected to the base plate 10. This facilitates the disassembly and installation of the conical block 6, making maintenance easier and preventing disinfection dead zones after sampling.

[0032] The working principle of this utility model is as follows: When it is necessary to sample the tissue inside a horseshoe crab, a micropore is first opened on the surface of the horseshoe crab, and the catheter 1 is inserted into the micropore to extend to the sampling site. Then, the handle 3 is held and the sampling piece is inserted into the catheter 1 through the guide tube 2. At this time, the push plate 8 is located on the left side of the groove 9, and the spring 14 is in a compressed state, so that the annular blade 11 is disengaged from the annular groove 12. When the conical block 6 moves to the sampling position, the force of the vertical part of the guide wire 7 can drive the conical block 6 to squeeze the tissue inside the horseshoe crab, so that the tissue is squeezed into the space between the annular blade 11 and the annular groove 12. After the tissue is squeezed to a certain extent, the push plate 8 is pulled. The push plate 8 drives the conical block 6 and the annular blade 11 to move upward through the guide wire 7, cutting the squeezed tissue and storing it in the storage cavity 5. Then, the guide tube 2 and the sampling piece are taken out, thus completing the sampling operation inside the horseshoe crab.

[0033] The above description is merely a preferred embodiment of this utility model. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of this utility model, and these improvements and modifications should also be considered within the scope of protection of this utility model. Structures, devices, and operating methods not specifically described or explained in this utility model, unless otherwise specified or limited, shall be implemented using conventional methods in the art.

Claims

1. A safe and precise limulus tissue punch biopsy sampling device, characterized in that: The device includes a conduit (1) and a guide tube (2). The guide tube (2) is located inside the conduit (1). A handle (3) is fixedly connected to the top of the guide tube (2). A through hole communicating with the guide tube (2) is opened on the top of the handle (3). A hollow tube (4) is fixedly connected to the bottom of the guide tube (2). The hollow tube (4) communicates with the guide tube (2). A sampling component is assembled at the bottom of the hollow tube (4). A guide wire (7) is provided in the inner cavity of the guide tube (2). The upper part of the guide wire (7) is a flexible part, and the lower part of the guide wire (7) is a vertical part. A control component is provided on the handle (3). The bottom end of the guide wire (7) passes through the hollow tube (4) and is connected to the sampling component. An elastic component is provided on the side wall of the guide wire (7) inside the hollow tube (4).

2. A safe and precise limulus tissue punch biopsy sampling device according to claim 1, characterized in that: The sampling component includes a base plate (10) fixedly connected to the bottom end of the guide wire (7), an annular blade (11) fixedly connected to the top surface of the base plate (10), a storage cavity (5) is opened on the bottom end face of the hollow tube (4), an annular groove (12) is opened on the bottom end face of the hollow tube (4), the annular blade (11) is adapted to the annular groove (12), and a conical block (6) is assembled on the bottom surface of the base plate (10).

3. The safe and precise limulus tissue punch biopsy sampling device according to claim 1, wherein: The control component includes a groove (9) on the top surface of the handle (3), a push plate (8) is slidably connected in the groove (9), the other end of the guide wire (7) is fixedly connected to the push plate (8), and the top surface of the push plate (8) is provided with anti-slip texture.

4. The safe and precise limulus tissue punch biopsy sampling device of claim 3, wherein: The through hole sidewall is fitted with a guide wheel (15), and the guide wire (7) contacts the guide wheel (15).

5. The safe and accurate horseshoe crab tissue puncture biopsy sampling device according to claim 1, characterized in that: The guide wire (7) has a baffle (13) fixedly connected to the side wall inside the hollow tube (4). A spring (14) is sleeved on the side wall of the guide wire (7). The two ends of the spring (14) are fixedly connected to the baffle (13) and the side wall of the hollow tube (4), respectively.

6. The safe and accurate horseshoe crab tissue puncture biopsy sampling device according to claim 2, characterized in that: The conical block (6) is threadedly connected to the base plate (10).

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