A pharmaceutical production granulating apparatus
By designing a pharmaceutical granulation equipment with a stirring component and a nozzle, the problem of incomplete discharge of pharmaceutical raw materials was solved, achieving full utilization of raw materials and convenient equipment cleaning.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- 滨州市检验检测中心(滨州市纺织纤维检验所)
- Filing Date
- 2025-04-29
- Publication Date
- 2026-06-19
AI Technical Summary
In existing pharmaceutical granulation equipment, it is impossible to guarantee that all raw materials are squeezed out when the drug is discharged from the granulation hole, resulting in waste of raw materials.
A pharmaceutical granulation device was designed, comprising a support frame, granulation cylinder, top plate, storage tank, conveying pipe, feed pipe, discharge pipe, bolts, drive assembly, mounting base, and nozzle. The drive assembly drives the stirring assembly to rotate, causing powder particles to collide with the inner wall of the conical hood and tumble and mix. The nozzle sprays adhesive to form granules, and the bottom plate and stirring assembly can be disassembled for cleaning.
This approach ensures full utilization of pharmaceutical raw materials, reduces waste, and facilitates equipment cleaning.
Smart Images

Figure CN224371372U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical production technology, specifically to a pharmaceutical granulation device. Background Technology
[0002] Granulation is the process of shaping materials such as powders, liquids, and aqueous solutions into granules of a specific shape and size. Granules are a common oral solid dosage form for medicines, especially traditional Chinese medicines, and the production of granule medicines requires granulation.
[0003] Chinese Patent CN219701844U discloses a granulation device for producing granular pharmaceuticals. It includes a granulation tank body, a motor on one side of the tank body, a rotating shaft connected to the motor's output shaft, a gear 1 fitted at one end of the rotating shaft, gear 1 meshing with gear 2, a rotating rod inserted inside gear 2, a cutting blade connected to the rotating rod via a connecting plate, and a scraper connected to the rotating rod via a stirring rod. A detachable mesh plate is connected to the granulation tank body by multiple bolts, and the detachable mesh plate has multiple granulation holes. Fixing plates are fixed on both sides of the granulation tank body, and an insert rod is fixed below the fixing plates. A sleeve is connected to the insert rod by bolt 1, a support plate is fixed below the sleeve, and a movable sleeve is connected to the sleeve by bolt 2. A horizontal plate is fixed to one side of the movable sleeve. This utility model provides a granulation device for producing granular pharmaceuticals that allows for easy cleaning of the device's interior, adjustment of granule output size, and adjustment of the receiving height.
[0004] However, the above technical solution has the following defects: In the above granulation device for producing granular drugs, the drug is discharged from the granulation hole, but the granulation box only has a stirring mechanism, which cannot guarantee that all the raw materials are squeezed out from the granulation hole, resulting in waste of raw materials. Utility Model Content
[0005] The purpose of this invention is to address the problems existing in the background technology by proposing a pharmaceutical granulation device.
[0006] The technical solution of this utility model is as follows: a pharmaceutical granulation device, comprising a support, a granulation cylinder, a top plate, a storage tank, a conveying pipe, a feed pipe, a bottom plate, a discharge pipe, bolts, a drive assembly, a mounting base, and a nozzle;
[0007] The pelletizing cylinder is connected to the support, the top plate is connected to the upper end of the pelletizing cylinder, the nozzle is connected to the top plate, the two ends of the conveying pipe are connected to the storage tank and the nozzle respectively, and the pump body is installed on the conveying pipe.
[0008] The bottom plate is connected to the lower end of the pelletizing cylinder, the mounting base is rotatably connected to the bottom plate, the drive assembly is connected to the bottom plate, the drive assembly is connected to the mounting base, and the mounting base is coaxially distributed with the pelletizing cylinder.
[0009] The upper end of the mixing assembly is connected to the mounting base, and multiple bolts are provided. The bolts pass through the mixing assembly and are threadedly connected to the mounting base.
[0010] Both the feed pipe and the discharge pipe are connected to the granulation cylinder. The feed pipe is located above the discharge pipe, and both the feed pipe and the discharge pipe are equipped with corresponding solenoid valves.
[0011] Preferably, the stirring assembly includes a protrusion, a mounting plate, and a fixing block a;
[0012] Multiple protrusions are provided, and each protrusion is connected to the upper surface of the mounting plate. The multiple protrusions are evenly distributed around the circumference of the mounting plate.
[0013] The fixing block a has two parts that are connected to the lower surface of the mounting plate. The number of bolts corresponds one-to-one with the fixing block a. The mounting base has two mounting slots. The two fixing blocks a are connected to the corresponding mounting slots. The bolts pass through the fixing blocks a and are connected to the mounting base by thread.
[0014] Preferably, the outer circumferential surface of the mounting plate is provided with a sealing ring, which is pressed against the inner wall of the granulation cylinder.
[0015] Preferably, the protrusion is arc-shaped, making the upper end of the stirring component wavy.
[0016] Preferably, it also includes a cleaning component, which includes a mounting rod, a fixing block b, and a scraper;
[0017] The fixing block b has two parts and is connected to the lower end of the mounting rod. The two fixing blocks b are connected to the mounting groove on the mounting base. The bolt passes through the fixing block b and is threadedly connected to the mounting base.
[0018] There are two scrapers, which are connected to the mounting rod and symmetrically distributed on the mounting rod. A rubber pad is provided at the end of the scraper near the inner wall of the granulation cylinder. The rubber pad is pressed against the inner wall of the granulation cylinder. The shape of the scraper corresponds to the shape of the inner wall of the granulation cylinder.
[0019] Preferably, the granulation cylinder is provided with a conical cover, which is coaxially distributed with the granulation cylinder. The top plate is connected to the upper end of the conical cover, and the inner diameter of the conical cover gradually decreases upward along the axis of the granulation cylinder.
[0020] Compared with the prior art, the above-mentioned technical solution of this utility model has the following beneficial technical effects:
[0021] In this invention, the drive assembly drives the mounting base and the stirring assembly to rotate. The stirring assembly stirs the powder, and the powder particles collide with the inner wall of the conical cover on the granulation cylinder, causing the powder particles to continue to roll and mix downwards. The adhesive is sprayed into the granulation cylinder through the nozzle, and the tumbling powder raw materials gradually adhere to each other and form granules.
[0022] The bottom plate of this utility model can be removed from the granulation cylinder, and the stirring component on the mounting base can be removed and replaced with a cleaning component, which facilitates cleaning of the stirring component and the inner wall of the granulation cylinder. Attached Figure Description
[0023] Figure 1 This is a perspective view of a pharmaceutical granulation device proposed in this utility model.
[0024] Figure 2 This is a schematic diagram of the structure of a pharmaceutical granulation device proposed in this utility model.
[0025] Figure 3 This is a schematic diagram of the cleaning component in one embodiment of the present invention.
[0026] Figure 4 This is a schematic diagram of the structure of the stirring assembly in one embodiment of the present invention.
[0027] Reference numerals: 1. Support; 2. Granulation cylinder; 3. Conical hood; 4. Top plate; 5. Storage hopper; 6. Conveying pipe; 7. Feed pipe; 8. Bottom plate; 9. Discharge pipe; 10. Bolt; 11. Drive assembly; 12. Mounting base; 13. Protrusion; 14. Mounting plate; 15. Nozzle; 16. Mounting rod; 17. Fixing block b; 18. Scraper; 19. Sealing ring; 20. Fixing block a. Detailed Implementation Example
[0028] like Figures 1-4 As shown, the present invention proposes a pharmaceutical granulation equipment, which includes a support 1, a granulation cylinder 2, a top plate 4, a storage tank 5, a conveying pipe 6, a feed pipe 7, a bottom plate 8, a discharge pipe 9, bolts 10, a drive assembly 11, a mounting base 12, and a nozzle 15.
[0029] The pelleting cylinder 2 is connected to the support 1, the top plate 4 is connected to the upper end of the pelleting cylinder 2, the nozzle 15 is connected to the top plate 4, the two ends of the conveying pipe 6 are respectively connected to the storage tank 5 and the nozzle 15, and the pump body is provided on the conveying pipe 6.
[0030] Furthermore, a conical cover 3 is provided on the granulation cylinder 2. The conical cover 3 is coaxially distributed with the granulation cylinder 2. The top plate 4 is connected to the upper end of the conical cover 3. The inner diameter of the conical cover 3 gradually decreases upward along the axial direction of the granulation cylinder 2.
[0031] The bottom plate 8 is connected to the lower end of the granulation cylinder 2, the mounting base 12 is rotatably connected to the bottom plate 8, the drive assembly 11 is connected to the bottom plate 8, the drive assembly 11 is connected to the mounting base 12 through transmission, and the mounting base 12 is coaxially distributed with the granulation cylinder 2.
[0032] The upper end of the stirring assembly is connected to the mounting base 12. Multiple bolts 10 are provided, and the bolts 10 pass through the stirring assembly and are threadedly connected to the mounting base 12.
[0033] Both the feed pipe 7 and the discharge pipe 9 are connected to the granulation cylinder 2. The feed pipe 7 is located above the discharge pipe 9. Both the feed pipe 7 and the discharge pipe 9 are equipped with corresponding individual solenoid valves.
[0034] In this invention, the raw material for granulation is fed into the feed pipe 7 and falls into the granulation cylinder 2. The drive component 11 drives the mounting base 12 and the stirring component to rotate. The stirring component stirs the powder, and the powder particles collide with the inner wall of the conical cover 3 on the granulation cylinder 2, causing the powder particles to continue to fall back and tumble and mix. The adhesive is sprayed into the granulation cylinder 2 through the nozzle 15, and the tumbling powder raw material gradually adheres to form granules. In this invention, the bottom plate 8 can be removed from the granulation cylinder 2, and the stirring component on the mounting base 12 can be removed and replaced with a cleaning component, which facilitates cleaning of the stirring component and the inner wall of the granulation cylinder 2. Example
[0035] like Figure 2 and Figure 4 As shown, the pharmaceutical granulation equipment proposed in this utility model, compared with Embodiment 1, the stirring component in this embodiment includes a protrusion 13, a mounting plate 14 and a fixing block a20;
[0036] Multiple protrusions 13 are provided, and each protrusion 13 is connected to the upper surface of the mounting plate 14. The multiple protrusions are evenly distributed around the circumference of the mounting plate 14.
[0037] The fixing block a20 has two parts and is connected to the lower surface of the mounting plate 14. The number of bolts 10 corresponds one-to-one with the fixing block a20. The mounting base 12 has two mounting slots. The two fixing blocks a20 are connected to the corresponding mounting slots. The bolts 10 pass through the fixing blocks a20 and are threadedly connected to the mounting base 12.
[0038] Furthermore, a sealing ring 19 is provided on the outer peripheral surface of the mounting plate 14, and the sealing ring 19 is pressed against the inner wall of the granulation cylinder 2.
[0039] Furthermore, the protrusion 13 is arc-shaped, making the upper part of the stirring component wavy.
[0040] In this embodiment, the fixing block a20 is connected to the mounting groove on the mounting base 12, and the bolt 10 fixes the mounting plate 14 on the mounting base 12. When the mounting base 12 rotates, it drives the stirring assembly to rotate. The protrusion 13 on the mounting plate 14 continuously collides and rolls the internal powder particles, so that the powder is mixed and granulated evenly. Example
[0041] like Figure 3 As shown, the pharmaceutical granulation equipment proposed in this utility model, compared with Embodiment 1, further includes a cleaning component, which includes a mounting rod 16, a fixing block b17 and a scraper 18;
[0042] The fixing block b17 has two parts and is connected to the lower end of the mounting rod 16. The two fixing blocks b17 are connected to the mounting groove on the mounting base 12. The bolt 10 passes through the fixing block b17 and is threadedly connected to the mounting base 12.
[0043] Two scrapers 18 are provided. The two scrapers 18 are connected to the mounting rod 16 and are symmetrically distributed on the mounting rod 16. A rubber pad is provided at one end of the scraper 18 near the inner wall of the granulation cylinder 2. The rubber pad is pressed against the inner wall of the granulation cylinder 2. The shape of the scraper 18 corresponds to the shape of the inner wall of the granulation cylinder 2.
[0044] In this embodiment, the fixing block b17 is connected to the mounting groove on the mounting base 12, and the two scrapers 18 are pressed against the inner wall of the granulation cylinder 2. The drive assembly 11 is started to drive the mounting base 12 to rotate on the base plate 8. The scrapers 18 can clean the inner wall of the granulation cylinder 2 and the conical cover 3, making it convenient to use.
[0045] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited thereto. Various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the spirit of the present invention.
Claims
1. A pharmaceutical granulation device, characterized in that, It includes a support (1), a pelletizing cylinder (2), a top plate (4), a storage tank (5), a conveying pipe (6), a feed pipe (7), a bottom plate (8), a discharge pipe (9), bolts (10), a drive assembly (11), a mounting base (12), and a nozzle (15); The pelletizing cylinder (2) is connected to the support (1), the top plate (4) is connected to the upper end of the pelletizing cylinder (2), the nozzle (15) is connected to the top plate (4), the two ends of the conveying pipe (6) are connected to the storage tank (5) and the nozzle (15) respectively, and the pump body is provided on the conveying pipe (6); The bottom plate (8) is connected to the lower end of the pelletizing cylinder (2), the mounting base (12) is rotatably connected to the bottom plate (8), the drive assembly (11) is connected to the bottom plate (8), the drive assembly (11) is connected to the mounting base (12) through transmission, and the mounting base (12) is coaxially distributed with the pelletizing cylinder (2). The upper end of the stirring assembly is connected to the mounting base (12), and multiple bolts (10) are provided. The bolts (10) pass through the stirring assembly and are threadedly connected to the mounting base (12). Both the feed pipe (7) and the discharge pipe (9) are connected to the granulation cylinder (2). The feed pipe (7) is located above the discharge pipe (9). Both the feed pipe (7) and the discharge pipe (9) are equipped with corresponding solenoid valves.
2. The pharmaceutical granulation equipment according to claim 1, characterized in that, The stirring assembly includes a protrusion (13), a mounting plate (14), and a fixing block a (20); There are multiple protrusions (13), and each protrusion (13) is connected to the upper surface of the mounting plate (14). The multiple protrusions are evenly distributed around the circumference of the mounting plate (14). The fixing block a (20) has two and is connected to the lower surface of the mounting plate (14). The number of bolts (10) corresponds one-to-one with the fixing block a (20). The mounting seat (12) has two mounting slots. The two fixing blocks a (20) are connected to the corresponding mounting slots. The bolts (10) pass through the fixing block a (20) and are threadedly connected to the mounting seat (12).
3. The pharmaceutical granulation equipment according to claim 2, characterized in that, A sealing ring (19) is provided on the outer peripheral surface of the mounting plate (14), and the sealing ring (19) is pressed against the inner wall of the granulation cylinder (2).
4. The pharmaceutical granulation equipment according to claim 2, characterized in that, The protrusion (13) is arc-shaped, making the upper part of the stirring component wavy.
5. A pharmaceutical granulation device according to claim 1 or 2, characterized in that, It also includes a cleaning component, which includes a mounting rod (16), a fixing block b (17), and a scraper (18); The fixing block b (17) has two lower ends connected to the mounting rod (16). The two fixing blocks b (17) are connected to the mounting groove on the mounting seat (12). The bolt (10) passes through the fixing block b (17) and is threadedly connected to the mounting seat (12). Two scrapers (18) are provided. The two scrapers (18) are connected to the mounting rod (16) and are symmetrically distributed on the mounting rod (16). A rubber pad is provided at one end of the scraper (18) near the inner wall of the granulation cylinder (2). The rubber pad is pressed against the inner wall of the granulation cylinder (2). The shape of the scraper (18) corresponds to the shape of the inner wall of the granulation cylinder (2).
6. The pharmaceutical granulation equipment according to claim 1, characterized in that, A conical cover (3) is provided on the granulation cylinder (2). The conical cover (3) is coaxially distributed with the granulation cylinder (2). The top plate (4) is connected to the upper end of the conical cover (3). The inner diameter of the conical cover (3) gradually decreases upward along the axis of the granulation cylinder (2).