A multi-channel tip taking and ejecting device

Abstract

This utility model discloses a multi-channel TIP removal and retraction device, relating to the field of in vitro diagnostic equipment technology. It includes a support frame disposed on one side of a base plate and equipped with multiple lead screw motors; a nut assembly sleeved on the lead screws of the lead screw motors; a TIP support plate connected to the nut assembly, with a guide shaft on the TIP support plate; a connecting plate connected to the guide shaft, with an elastic element sleeved on the guide shaft located between the TIP support plate and the connecting plate; an adapter sleeve disposed on the connecting plate, with an adapter at its lower end for connecting the TIP; a TIP retraction baffle fixed to the outside of the base plate, having interconnected through holes and oblong holes; and a control unit establishing a signal connection with the lead screw motors. This multi-channel TIP removal and retraction device achieves the technical effect of improving operational efficiency and reducing repetitive labor.

Description

Technical Field

[0001] This utility model relates to the field of in vitro diagnostic equipment technology, and in particular to a multi-channel TIP removal device. Background Technology

[0002] In molecular diagnostics, nucleic acid is extracted from the subject and then quantitatively analyzed using instruments. The efficiency and stability of nucleic acid extraction are important factors affecting molecular diagnostics.

[0003] Existing technologies typically utilize pipettes in conjunction with pick-up and drop-off devices to collect and transfer liquid samples. However, most existing methods operate on a single TIP (pipette tip or pipette tip). When multiple identical test reagents are required for the same sample, numerous repetitive operations are necessary, resulting in long running times and a poor user experience.

[0004] Therefore, how to provide a multi-channel TIP take-off and removal device to improve operational efficiency and reduce repetitive labor is a technical problem that needs to be solved by those skilled in the art. Utility Model Content

[0005] The purpose of this invention is to provide a multi-channel TIP retrieval device to solve the technical problem of low operating efficiency of existing TIP retrieval devices.

[0006] To achieve the above objectives, this utility model provides a multi-channel TIP retrieval device, comprising:

[0007] A bracket is disposed on one side of the substrate, and multiple lead screw motors are mounted on the bracket.

[0008] A nut pair is sleeved on the lead screw of each of the lead screw motors, and a nut pair fixing plate is fixed on the outer peripheral surface of each nut pair;

[0009] TIP support plates are detachably connected to the bottom of each of the nut pair fixing plates, and each of the TIP support plates is provided with two guide shafts;

[0010] A connecting plate is slidably connected to two guide shafts. Each guide shaft has a limiting member at its lower end. An elastic member is sleeved on the guide shaft located between the TIP support plate and the connecting plate.

[0011] An adapter sleeve is provided on the connecting plate, and an adapter is provided at its lower end. The adapter is used to connect the TIP.

[0012] The TIP baffle is fixed to the outside of the substrate and has interconnected through holes and waist-shaped holes;

[0013] The control unit establishes a signal connection with the lead screw motor.

[0014] Preferably, a transition plate is vertically provided on the side of the TIP support plate away from the substrate, a sensing sensor is provided on the transition plate, and a sensing sensor sheet is provided on the connecting plate. The sensing sensor establishes a signal connection with the control unit to determine whether the adapter is in the TIP take-up state or TIP take-down state.

[0015] Preferably, the substrate is provided with a plurality of slide rails, and each TIP support plate is provided with a slider that slides and engages with the slide rails on the side facing the substrate.

[0016] Preferably, the substrate is provided with a Z-axis origin positioning sensor at the lower end of the bracket, and the TIP support plate is provided with a Z-axis origin positioning sensor sensing sheet, and the Z-axis origin positioning sensor establishes a signal connection with the control unit.

[0017] Preferably, a plurality of plunger pumps are provided in the middle of the back side of the substrate, and the plunger pumps are used for liquid extraction or separation of the TIP.

[0018] Preferably, the TIP ejection baffle is connected to the top of the TIP ejection bracket.

[0019] Preferably, the elastic element is a compression coil spring.

[0020] Preferably, a pressure sensor bracket is provided on the back side of the substrate, and a pressure sensor is provided on the pressure sensor bracket.

[0021] Preferably, a motor bracket is provided on the bottom back side of the substrate, and a stepper motor is provided on the motor bracket. The stepper motor is connected to the leakage receiving bracket through a motor connector. The leakage receiving bracket is located below the substrate and has multiple liquid receiving boxes. The stepper motor can drive the liquid receiving boxes to move so that the liquid receiving boxes are away from the TIP or located below the TIP. The stepper motor establishes a signal connection with the control unit.

[0022] Preferably, the motor bracket is provided with a receiving plate positioning sensor, the motor connector is provided with a receiving plate positioning sensor induction plate, and the receiving plate positioning sensor establishes a signal connection with the control unit.

[0023] Compared to the aforementioned background technology, this utility model provides a multi-channel TIP retrieval and removal device. When a TIP needs to be retrieved, the control unit sends a start signal to each lead screw motor. The lead screw motors start working, driving the lead screw to rotate. As the lead screw rotates, the nut assembly reciprocates linearly on the lead screw. Since the nut assembly fixing plate is fixedly connected to the nut assembly, the nut assembly fixing plate drives the TIP support plate to move downwards together. When the TIP support plate moves downwards, it drives the connecting plate downwards through the guide shaft. During the downward movement of the connecting plate, the adapter sleeve and adapter also move downwards. When the adapter moves to the position of the TIP, the adapter precisely aligns and connects with the upper end of the TIP, at which point the TIP is fixed to the adapter. After the sample operation is completed, the TIP needs to be removed. The control unit sends a reverse signal to the lead screw motor, driving the lead screw to rotate in the opposite direction. The nut assembly moves upwards on the lead screw, driving the nut assembly fixing plate, TIP support plate, connecting plate, adapter sleeve, and adapter upwards together. As the adapter and TIP move upwards, the TIP gradually enters the through hole of the TIP retraction baffle. When the TIP moves to the position of the oblong hole, because the diameter of the oblong hole is smaller than the maximum outer diameter of the TIP, the TIP separates from the adapter due to the obstruction of the oblong hole. The lead screw motor continues to work, moving the nut pair, nut pair fixing plate, TIP support plate, connecting plate and other components back to the initial position, waiting for the next TIP gripping and operation.

[0024] In summary, this application adopts a multi-channel design, in which multiple lead screw motors, nut pairs, TIP support plates, adapter sleeves and other related components work independently yet collaboratively. Each channel can independently control the gripping, transfer, operation and withdrawal process of the corresponding TIP. By controlling each lead screw motor through the control unit, multiple TIPs can be operated simultaneously or separately, which greatly improves work efficiency. Attached Figure Description

[0025] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0026] Figure 1 This is an isometric schematic diagram of a multi-channel TIP retrieval device provided in an embodiment of the present invention;

[0027] Figure 2 for Figure 1 A side view;

[0028] Figure 3 for Figure 1 A diagram of the back of the building;

[0029] Figure 4 This is a schematic diagram of the TIP ejection baffle structure provided in an embodiment of the present utility model.

[0030] in:

[0031] 1-Baseboard, 2-Bracket, 3-Screw motor, 4-Nut pair, 5-Nut pair fixing plate, 6-TIP support plate, 7-Guide shaft, 8-Connecting plate, 9-Elastic element, 10-Adapter sleeve, 11-Adapter, 12-TIP, 13-TIP retraction baffle, 14-Through hole, 15-Oval hole, 16-Transition plate, 17-Induction sensor, 18-Induction sensor sensing element, 19-Slide rail, 20-Z-axis origin positioning sensor, 21-Z-axis origin positioning sensor sensing element, 22-Plunger pump, 23-TIP retraction bracket, 24-Pressure sensor bracket, 25-Pressure sensor, 26-Motor bracket, 27-Stepper motor, 28-Motor connector, 29-Leakage receiving bracket, 30-Leakage receiving box, 31-Receiving plate positioning sensor, 32-Receiving plate positioning sensor sensing element. Detailed Implementation

[0032] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0033] To enable those skilled in the art to better understand the present invention, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0034] See Figures 1-4This application provides a multi-channel TIP retraction device, comprising a base plate 1 connected to an XY-axis linkage mechanism; a bracket 2 disposed on one side of the base plate 1, with multiple lead screw motors 3 mounted on the bracket 2, the lead screw ends of the lead screw motors 3 passing through the bracket 2 and extending downward; a nut assembly 4 sleeved on the lead screw of each lead screw motor 3, the lead screw motor 3 driving the nut assembly 4 to reciprocate linearly, and a nut assembly fixing plate 5 fixed on the outer circumferential surface of each nut assembly 4; a TIP support plate 6 detachably connected to the bottom of each nut assembly fixing plate 5, each TIP support plate 6 having two guide shafts 7, the guide shafts 7 being fixed on the TIP support plate 6; and a connecting plate 8, which slides... The system is connected to two guide shafts 7, each with a limiting element at its lower end. An elastic element 9 is fitted onto the guide shaft 7 located between the TIP support plate 6 and the connecting plate 8. An adapter sleeve 10 is mounted on the connecting plate 8, with an adapter 11 at its lower end. The adapter 11 is used to connect to the TIP 12, where TIP refers to a biological consumable used to insert into a test tube to extract samples. A TIP retraction baffle 13 is fixed to the outside of the base plate 1 and has interconnected through holes 14 and waist-shaped holes 15. The diameter of the through holes 14 is larger than the maximum outer diameter of the TIP 12, and the diameter of the waist-shaped holes 15 is smaller than the maximum outer diameter of the TIP 12. A control unit is established with the lead screw motor 3 for signal connection.

[0035] In other words, the base plate 1 serves as the basic support component of the device and is stably placed on the experimental platform. The bracket 2 is fixed to one side of the base plate 1 to provide an installation position for the lead screw motor 3. Multiple lead screw motors 3 are set on the bracket 2. Specifically, the number of lead screw motors 3 can be selected as 3. The end of the lead screw passes through the bracket 2 and extends downward. The nut pair 4 is respectively sleeved on the lead screw of each lead screw motor 3.

[0036] Work process:

[0037] Initial state: When the lead screw motor 3 is not started, the nut assembly 4 is in the initial position of the lead screw. At this time, the nut assembly fixing plate 5 is also at the corresponding height. The TIP support plate 6 is fixed to the bottom of the nut assembly fixing plate 5 by a detachable connection. The adapter sleeve 10 and the adapter 11 are in a high position together with the connecting plate 8. The adapter 11 is not connected to the TIP 12. The TIP baffle 13 is fixed to the outside of the base plate 1, that is, fixed to the experimental table.

[0038] TIP scraping process:

[0039] The control unit controls the movement of the XY axis linkage mechanism, so that the adapter 11 on the base plate 1 moves above the TIP disk. When it is necessary to grab the TIP 12, the control unit sends a start signal to each lead screw motor 3, and the lead screw motor 3 starts to work, driving the lead screw to rotate.

[0040] As the lead screw rotates, the nut assembly 4 moves linearly along the lead screw. Since the nut assembly fixing plate 5 is fixedly connected to the nut assembly 4, the nut assembly fixing plate 5 drives the TIP support plate 6 to move downward together. When the TIP support plate 6 moves downward, it drives the connecting plate 8 to move downward through the guide shaft 7. During the downward movement of the connecting plate 8, the adapter sleeve 10 and the adapter 11 also move downward accordingly.

[0041] When the adapter 11 moves to the position of TIP12, the upper end of the adapter 11 and TIP12 are precisely aligned and connected. At this time, TIP12 is fixed on the adapter 11. When the adapter 11 and TIP12 are aligned, the connecting plate 8 slides upward on the guide shaft 7, and the elastic element 9 is gradually compressed.

[0042] After the sample aspiration and separation operation is completed, you need to exit the operation via TIP12.

[0043] TIP return process:

[0044] The control unit generates the optimal movement path and instructions based on the pre-set position information of the TIP retraction baffle 13, and sends them to the XY axis linkage mechanism. TIP12 is located directly above the through hole 14 on the TIP retraction baffle 13.

[0045] After the control unit confirms that TIP12 is accurately aligned with the through hole 14, it controls the lead screw motor 3 to drive the nut assembly 4 to move downward. As TIP12 descends smoothly, it gradually approaches and passes through the through hole 14. Since the diameter of the through hole 14 is larger than the maximum outer diameter of TIP12, it ensures that TIP12 can pass through smoothly. After TIP12 descends to a certain height, the lead screw motor 3 stops working.

[0046] Next, the control unit sends a horizontal movement command to the XY axis linkage mechanism, driving TIP12 to move horizontally and accurately move TIP12 to the position of the waist-shaped hole 15.

[0047] Once TIP12 is positioned within the oblong hole 15, the control screw motor 3 drives the nut assembly 4 upward. Because the diameter of the oblong hole 15 is smaller than the maximum outer diameter of TIP12, TIP12 is blocked by the edge of the oblong hole 15 as it moves upward with the nut assembly 4. Meanwhile, the adapter 11 continues to move upward with the connecting plate 8, gradually separating TIP12 from the adapter 11. At this point, the elastic element 9 opens and returns to its original state.

[0048] Based on the above embodiments, the XY axis linkage mechanism is a direct use of existing technology. The specific mechanism will not be described in detail. For details, please refer to the XY translation mechanism disclosed in CN202882489U.

[0049] Based on the above embodiments, a transition plate 16 is vertically provided on the side of the TIP support plate 6 away from the substrate 1. A sensing sensor 17 is provided on the transition plate 16, and a sensing sensor sheet 18 is provided on the connecting plate 8. The sensing sensor 17 establishes a signal connection with the control unit to determine whether the adapter 11 is in the TIP take-up state or TIP take-down state.

[0050] In other words, in the TIP-removal state, as the connecting plate 8 changes position, the sensing element 18 also moves. When it moves into the sensing range of the sensing element 17, the sensing element 18 receives a signal from the sensing element and transmits this signal to the control unit. Upon receiving this signal, the control unit can determine that the adapter 11 is in the TIP-removal state. In the TIP-disconnection state, the connecting plate 8 moves in the opposite direction, and the sensing element 18 leaves the sensing range of the sensing element 17. The signal state of the sensing element 17 changes, and this information is transmitted to the control unit again. Based on this, the control unit determines that the adapter 11 is in the TIP-disconnection state.

[0051] Based on the above embodiments, the substrate 1 is provided with a plurality of slide rails 19, and each TIP support plate 6 is provided with a slider that slides in cooperation with the slide rail 19 on the side facing the substrate 1, thereby facilitating the stable sliding of the TIP support plate 6.

[0052] Based on the above embodiments, the base plate 1 is provided with a Z-axis origin positioning sensor 20 at the lower end of the support 2, and the TIP support plate 6 is provided with a Z-axis origin positioning sensor sensing plate 21. The Z-axis origin positioning sensor 20 establishes a signal connection with the control unit.

[0053] In other words, the Z-axis origin position sensor 20 establishes a signal connection with the control unit. When the device is started or a specific reset operation is performed, the TIP support plate 6 moves under the drive of the lead screw motor 3. When the TIP support plate 6 moves to the Z-axis origin position, the Z-axis origin position sensor sensing plate 21 enters the sensing range of the Z-axis origin position sensor 20. The sensor is triggered and then sends a signal to the control unit. After receiving the signal, the control unit can identify that the TIP support plate 6 has reached the Z-axis origin position.

[0054] Based on the above embodiments, a plurality of plunger pumps 22 are provided in the middle of the back side of the substrate 1. The plunger pumps 22 are used for TIP12 to draw or separate liquid.

[0055] Based on the above embodiment, the TIP ejection baffle 13 is connected to the top of the TIP ejection bracket 23.

[0056] Based on the above embodiments, the elastic element 9 is a compression helical spring.

[0057] Based on the above embodiments, a pressure sensor bracket 24 is provided on the back side of the substrate 1, and a pressure sensor 25 is provided on the pressure sensor bracket 24.

[0058] Based on the above embodiments, a motor bracket 26 is provided on the bottom back side of the substrate 1, and a stepper motor 27 is provided on the motor bracket 26. The stepper motor 27 is connected to the drain support 29 through the motor connector 28. The drain support 29 is located below the substrate 1 and is provided with a plurality of drain boxes 30. The stepper motor 27 can drive the drain boxes 30 to move so that the drain boxes 30 are away from TIP12 or located below TIP12. The stepper motor 27 establishes a signal connection with the control unit.

[0059] In other words, the drip tray 29 is located below the substrate 1, allowing for the reasonable installation of multiple drip collection boxes 30. The drip collection boxes 30 are fixed to the drip tray 29 using slots, clips, or other means, facilitating disassembly and replacement. The drip collection boxes 30 are used to collect any liquid that may drip from TIP12, preventing liquid contamination of the working environment.

[0060] Stepper motor 27 can drive the liquid receiving box 30 to move so that the liquid receiving box 30 is away from TIP12 or located below TIP12. When the control unit issues a command according to the working status of the device, stepper motor 27 starts to operate, driving the liquid receiving bracket 29 and the liquid receiving box 30 to move through motor connector 28.

[0061] The stepper motor 27 establishes a signal connection with the control unit. The control unit can accurately control the start, stop, forward and reverse rotation, and speed of the stepper motor 27 according to the overall working process and status of the device, so as to realize the automated movement control of the liquid receiving box 30.

[0062] Based on the above embodiment, a receiving tray positioning sensor 31 is provided on the motor bracket 26, and a receiving tray positioning sensor sensing element 32 is provided on the motor connector 28. The receiving tray positioning sensor 31 establishes a signal connection with the control unit. Specifically, the receiving tray positioning sensor 31 establishes a signal connection with the control unit. When the stepper motor 27 drives the leak-collecting bracket 29 and the receiving box 30 to move, the motor connector 28 moves accordingly. When the receiving box 30 moves to the predetermined position, that is, the receiving tray is in position, the receiving tray positioning sensor sensing element 32 enters the sensing range of the receiving tray positioning sensor 31, the sensor is triggered, and immediately sends a signal to the control unit. After receiving the signal, the control unit can accurately determine that the receiving box 30 has reached the designated position, and then further control the stepper motor 27 according to the actual working requirements, such as stopping the motor operation.

[0063] The working principle of a multi-channel TIP retrieval device is as follows:

[0064] TIP scraping process:

[0065] The control unit controls the movement of the XY-axis linkage mechanism, causing the adapter 11 on the base plate 1 to move above the TIP disk. Based on the preset TIP disk position information, the control unit sends a movement command to the XY-axis linkage mechanism, thereby moving the base plate 1 to ensure that the adapter 11 accurately reaches above the TIP 12. Furthermore, by utilizing fixed coordinate positions and a closed-loop stepper motor, the accurate positioning of the movement is guaranteed.

[0066] When TIP12 needs to be grasped, the control unit sends a start signal to each lead screw motor 3, and the lead screw motor 3 starts working, driving the lead screw to rotate. As the lead screw rotates, the nut assembly 4 moves linearly on the lead screw. Since the nut assembly fixing plate 5 is fixedly connected to the nut assembly 4, the nut assembly fixing plate 5 drives the TIP support plate 6 to move downward together. The TIP support plate 6 slides stably on the slide rail 19 of the base plate 1 through the slider, ensuring the smoothness of the descent process. At the same time, when the TIP support plate 6 moves downward, it drives the connecting plate 8 to move downward through the guide shaft 7. During the downward movement of the connecting plate 8, the adapter sleeve 10 and the adapter 11 also move downward.

[0067] When the adapter 11 moves to the position of the TIP 12, the upper end of the adapter 11 and the TIP 12 are precisely aligned and connected. At this time, the TIP 12 is fixed on the adapter 11. When the adapter 11 and the TIP 12 are aligned, the connecting plate 8 slides upward on the guide shaft 7, and the elastic element 9 is gradually compressed. The compression of the elastic element 9 plays a buffering role, avoiding excessive impact force when the adapter 11 and the TIP 12 are aligned, and protecting the TIP 12 and the adapter 11 from damage.

[0068] As the position of the connecting plate 8 changes, the sensing element 18 of the sensing sensor also moves. When it moves into the sensing range of the sensing sensor 17, the sensing sensor 17 receives the signal from the sensing element and transmits the signal to the control unit. After receiving the signal, the control unit can determine that the adapter 11 is in the TIP state.

[0069] Sample aspiration procedure:

[0070] After TIP12 is successfully grasped, the control unit sends another command to the XY-axis linkage mechanism, causing it to move the grasped TIP12 above the mother tube (the original container holding the specimen and sample). Upon reaching the designated position, the control unit controls the lead screw motor to operate, driving the nut assembly 4, nut assembly fixing plate 5, TIP support plate 6, connecting plate 8, adapter sleeve 10, and adapter 11 to move collaboratively. This causes the grasped TIP12 to gradually move vertically downwards into the mother tube. The control unit can then control the plunger pump 22 to start operating, thus smoothly drawing the sample from the mother tube into TIP12. During sample aspiration, the pressure sensor 25 plays a real-time monitoring role, monitoring pressure changes.

[0071] Sample transfer procedure:

[0072] After the sample aspiration operation is completed, the control unit controls the XY axis linkage mechanism to move the TIP12, which holds the sample, to the top of the sub-tube (the container to be dispensed and hold the specimen and sample). The control unit then controls the lead screw motor to move the TIP12 vertically downward into the sub-tube for dispensing.

[0073] TIP return process:

[0074] The control unit generates a movement path and instructions based on the pre-set position information of the TIP baffle 13, and sends them to the XY axis linkage mechanism.

[0075] After the control unit confirms that TIP12 is accurately aligned with the through hole 14, it controls the lead screw motor 3 to drive the nut assembly 4 downward. As TIP12 descends smoothly, it gradually approaches and passes through the through hole 14. Since the diameter of the through hole 14 is larger than the maximum outer diameter of TIP12, ensuring that TIP12 can pass through smoothly, the lead screw motor 3 stops working after TIP12 has descended a certain height.

[0076] Next, the control unit sends a horizontal movement command to the XY axis linkage mechanism, driving TIP12 to move horizontally and accurately move TIP12 to the position of the waist-shaped hole 15.

[0077] Once TIP12 is positioned in the oblong hole 15, the control screw motor 3 drives the nut assembly 4 to move upward. Since the diameter of the oblong hole 15 is smaller than the maximum outer diameter of TIP12, TIP12 will be blocked by the edge of the oblong hole 15 as it moves upward with the nut assembly 4. Meanwhile, the adapter 11 continues to move upward with the connecting plate 8, causing TIP12 to gradually separate from the adapter 11. At this point, the elastic element 9 opens and returns to its original state.

[0078] When the connecting plate 8 moves in the reverse direction, the sensing element 18 of the sensing sensor moves out of the sensing range of the sensing sensor 17. The signal state of the sensing sensor 17 changes, and this information is transmitted to the control unit again. Based on this, the control unit determines that the adapter 11 is in the TIP unplugging state. The control unit accurately determines the completion status of the TIP unplugging operation based on the signal change of the sensing sensor 17 and the preset logic program.

[0079] When the device is started or a specific reset operation is performed, the TIP support plate 6 moves under the drive of the lead screw motor 3. When the TIP support plate 6 moves to the Z-axis origin position, the Z-axis origin positioning sensor 21 enters the sensing range of the Z-axis origin positioning sensor 20, the sensor is triggered, and then sends a signal to the control unit. After receiving the signal, the control unit can recognize that the TIP support plate 6 has reached the Z-axis origin position. Based on the signal from the Z-axis origin positioning sensor 20, the control unit calibrates and resets the position of the device.

[0080] The drip tray 29 is located below the base plate 1, allowing for the proper mounting of multiple drip trays 30. The drip trays 30 are secured to the drip tray 29 using slots, clips, or other means, facilitating disassembly and replacement. The drip trays 30 are used to collect any liquid that may drip from the TIP12, preventing liquid contamination of the working environment. The stepper motor 27 can drive the drip trays 30 to move them away from or below the TIP12. When the XY-axis linkage mechanism is operating, the control unit positions the drip trays 30 below the TIP12; when the lead screw motor 3 is operating, the control unit moves the drip trays 30 away from the TIP12.

[0081] This application employs a multi-channel design, where multiple lead screw motors 3, nut pairs 4, TIP support plates 6, and adapter sleeves 10 operate independently yet collaboratively. Each channel can independently control the grasping, transferring, operating, and retraction processes of its corresponding TIP 12. Through precise control of each lead screw motor 3 by the control unit, multiple TIPs 12 can be operated simultaneously or separately, significantly improving work efficiency and meeting the high-throughput and automated processing requirements of experiments such as molecular diagnostics. During multi-channel collaborative operation, the control unit independently controls the lead screw motor 3 of each channel according to preset programs and experimental requirements. Simultaneously, the sensor 17 monitors the position of the connecting plate 8, the status of the adapter 11, and the position and orientation of the TIP 12 in real time for each channel. When a channel completes a TIP retrieval or retraction operation, the control unit can promptly adjust the state of the lead screw motor 3 of that channel, putting it into standby or preparing for the next operation, while other channels can continue operating, thus achieving efficient collaborative operation of multiple channels.

[0082] It should be noted that in this specification, relational terms such as first and second are used only to distinguish one entity from several other entities, and do not necessarily require or imply any such actual relationship or order between these entities.

[0083] This article uses specific examples to illustrate the principles and implementation methods of this utility model. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of this utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made to this utility model without departing from the principles of this utility model, and these improvements and modifications also fall within the protection scope of the claims of this utility model.

Claims

1. A multi-channel TIP retrieval and removal device, characterized in that, include: A bracket (2) is provided on one side of the base plate (1), and a plurality of lead screw motors (3) are provided on the bracket (2). Nut pair (4) is sleeved on the lead screw of each lead screw motor (3), and a nut pair fixing plate (5) is fixed on the outer peripheral surface of each nut pair (4). TIP support plate (6) is detachably connected to the bottom of each of the nut pair fixing plates (5), and each of the TIP support plates (6) is provided with two guide shafts (7). The connecting plate (8) is slidably connected to the two guide shafts (7). Each guide shaft (7) has a limiting member at its lower end. An elastic member (9) is sleeved on the guide shaft (7) located between the TIP support plate (6) and the connecting plate (8). An adapter sleeve (10) is provided on the connecting plate (8), and an adapter (11) is provided at its lower end. The adapter (11) is used to connect the TIP (12). The TIP baffle (13) is fixed to the outside of the substrate (1) and has interconnected through holes (14) and waist-shaped holes (15). The control unit establishes a signal connection with the lead screw motor (3).

2. The multi-channel TIP retrieval device according to claim 1, characterized in that, The TIP support plate (6) has a vertical transition plate (16) on the side away from the base plate (1). The transition plate (16) is provided with a sensing sensor (17). The connecting plate (8) is provided with a sensing sensor sheet (18). The sensing sensor (17) establishes a signal connection with the control unit to determine whether the adapter (11) is in the TIP take-up state or TIP take-down state.

3. A multi-channel TIP retrieval device according to claim 2, characterized in that, The substrate (1) is provided with a plurality of slide rails (19), and each TIP support plate (6) is provided with a slider that slides in cooperation with the slide rail (19) on the side facing the substrate (1).

4. A multi-channel TIP retrieval device according to claim 3, characterized in that, The base plate (1) is provided with a Z-axis origin positioning sensor (20) at the lower end of the bracket (2), and the TIP support plate (6) is provided with a Z-axis origin positioning sensor sensing plate (21). The Z-axis origin positioning sensor (20) establishes a signal connection with the control unit.

5. A multi-channel TIP retrieval device according to claim 1, characterized in that, The substrate (1) is provided with a plurality of plunger pumps (22) in the middle of the back side, and the plunger pumps (22) can make the TIP (12) pump or separate liquid.

6. A multi-channel TIP retrieval device according to claim 1, characterized in that, The TIP ejection baffle (13) is connected to the top of the TIP ejection bracket (23).

7. A multi-channel TIP retrieval device according to claim 1, characterized in that, The elastic element (9) is a compression helical spring.

8. A multi-channel TIP retrieval device according to claim 1, characterized in that, The back side of the substrate (1) is provided with a pressure sensor bracket (24), and a pressure sensor (25) is provided on the pressure sensor bracket (24). The pressure sensor (25) establishes a signal connection with the control unit.

9. A multi-channel TIP retrieval device according to any one of claims 1-8, characterized in that, The bottom back side of the substrate (1) is provided with a motor bracket (26), and a stepper motor (27) is provided on the motor bracket (26). The stepper motor (27) is connected to the leakage receiving bracket (29) through a motor connector (28). The leakage receiving bracket (29) is located below the substrate (1). The leakage receiving bracket (29) is provided with multiple liquid receiving boxes (30). The stepper motor (27) can drive the liquid receiving boxes (30) to move so that the liquid receiving boxes (30) are away from the TIP (12) or located below the TIP (12). The stepper motor (27) establishes a signal connection with the control unit.

10. A multi-channel TIP retrieval device according to claim 9, characterized in that, A receiving plate position sensor (31) is provided on the motor bracket (26), and a receiving plate position sensor induction plate (32) is provided on the motor connector (28). The receiving plate position sensor (31) establishes a signal connection with the control unit.

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