A separation and purification apparatus

Abstract

The utility model relates to the technical field of biological medicine production, concretely relates to a separation and purification equipment, including jar body and separation mechanism, separation mechanism includes apron, internal thread cylinder, outer thread cylinder, drive assembly, mounting ring, centrifugal cylinder, threaded rod and mounting seat, internal thread cylinder is fixedly connected with jar body, and is located the top of jar body, outer thread cylinder is fixedly connected with apron, internal thread cylinder is connected with outer thread cylinder threadedly, drive assembly sets up on apron, mounting ring sets up on the output of drive assembly, centrifugal cylinder is fixedly connected with mounting ring, and is located the inside of mounting ring, mounting seat is fixedly connected with one end of internal thread cylinder, and is located jar body, threaded rod is connected with apron threadedly, and extends to the inside of mounting seat, the device adopts detachable mechanism, when the device work is completed, can dismantle jar body, to facilitate the operator to the component of jar body inside to clean, and then improved the practicability of the device.

Description

Technical Field

[0001] This utility model relates to the field of biopharmaceutical production technology, and in particular to a separation and purification device. Background Technology

[0002] Pharmaceutical intermediates are chemical raw materials or products used in drug synthesis processes. During the production and processing of pharmaceutical intermediates, the resulting compounds often require purification. Currently, when removing impurities from liquid pharmaceutical intermediates using filtration, the liquid's own gravity is typically used to separate it through a filter screen. This process is time-consuming and results in low impurity filtration efficiency.

[0003] A purification device for the production of pharmaceutical intermediates is disclosed in patent application CN 216457266 U. This device involves injecting liquid pharmaceutical intermediates into a tank via an inlet valve, then closing the inlet valve. Through the cooperation of a power component and a transmission rod, a circular plate drives a piston ring and a filter basket upwards. The filter basket compresses the liquid pharmaceutical intermediates, causing it to pass quickly through the basket. Impurities in the liquid pharmaceutical intermediates are trapped inside the filter basket, which is then discharged through a drain valve. The filter basket can be removed for cleaning by disassembling the top cover, thus achieving high efficiency in impurity filtration and separation.

[0004] After separating and purifying pharmaceutical intermediates into liquids, the device needs to be thoroughly cleaned to ensure that no liquid remains in the device. However, in the existing technology, the tank is difficult to open, and cleaning inside the tank is relatively difficult, resulting in low practicality of the device. Utility Model Content

[0005] The purpose of this invention is to provide a separation and purification device that solves the problem that the device needs to be thoroughly cleaned after separating and purifying pharmaceutical intermediate liquids to ensure that no liquid remains in the device. However, in the prior art, the tank is difficult to open and the cleaning inside the tank is relatively difficult, resulting in low practicality of the device.

[0006] To achieve the above objectives, this utility model provides a separation and purification device, including a tank and a separation mechanism. The separation mechanism includes a cover plate, an internally threaded cylinder, an externally threaded cylinder, a drive assembly, a mounting ring, a centrifuge cylinder, a threaded rod, and a mounting base. The internally threaded cylinder is fixedly connected to the tank and located above the tank. The externally threaded cylinder is fixedly connected to the cover plate and located below the cover plate. The internally threaded cylinder is threadedly connected to the externally threaded cylinder and located inside the externally threaded cylinder. The drive assembly is disposed on the cover plate. The mounting ring is disposed on the output end of the drive assembly. The centrifuge cylinder is fixedly connected to the mounting ring and located inside the mounting ring. The mounting base is fixedly connected to one end of the internally threaded cylinder and located inside the tank. The threaded rod is threadedly connected to the cover plate and extends into the mounting base.

[0007] The drive assembly includes a drive motor, a drive shaft, and a connecting frame. The drive motor is fixedly connected to the cover plate, the drive shaft is fixedly connected to the output end of the drive motor and extends into the tank body, the connecting frame is fixedly connected to one end of the drive shaft, and the mounting ring is fixedly connected to the connecting frame.

[0008] The separation mechanism further includes a funnel and a valve. The funnel is fixedly connected to the tank and located below the tank, and the valve is disposed on the funnel.

[0009] The separation mechanism further includes a support assembly, which includes a support ring and multiple sliding components. The support assembly is disposed inside the tank, the support ring is fixedly connected to the tank and located below the mounting ring, and the multiple sliding components are disposed on the support ring.

[0010] The sliding assembly includes a support frame, a rotating roller, and a pulley. The mounting ring has a groove. The support frame is fixedly connected to the support ring and is located above the support ring. The rotating roller is rotatably connected to the pulley and the support frame, and the pulley is located inside the support frame. One end of the pulley is slidably connected to the mounting ring and is located inside the groove.

[0011] This utility model discloses a separation and purification device. When using this device to separate and purify pharmaceutical intermediates, the pharmaceutical intermediates are poured into the tank. Part of the pharmaceutical intermediates pass through the separation cylinder. The drive assembly is then controlled to rotate the mounting ring and the separation cylinder. At this time, one end of the threaded rod is inserted into the mounting base to ensure that the cover plate does not detach from the tank when the separation cylinder rotates. The rotation of the separation cylinder centrifugally separates the pharmaceutical intermediates from the separation cylinder, thus completing the separation of the pharmaceutical intermediates. When cleaning the components in the tank, the threaded rod is rotated to move it away from the mounting base. Then, the cover plate and the external threaded cylinder are rotated to separate the internal threaded cylinder from the external threaded cylinder. Finally, the cover plate is pulled upward to move the mounting ring and the separation cylinder away from the tank, so that the operator can clean the tank and the separation cylinder, thereby improving the practicality of the device. Attached Figure Description

[0012] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.

[0013] Figure 1 This is a schematic diagram of the separation and purification equipment of this utility model.

[0014] Figure 2 This is a cross-sectional view of the separation and purification equipment of this utility model.

[0015] Figure 3 This is a schematic diagram of the structure below the cover plate of this utility model.

[0016] Figure 4 This is a schematic diagram of the internal structure of the tank of this utility model.

[0017] Figure 5 This is the utility model Figure 4 Enlarged view of the local structure at point A.

[0018] 101-Tank body, 102-Internal threaded cylinder, 103-External threaded cylinder, 104-Cover plate, 105-Function funnel, 106-Valve, 107-Mounting base, 108-Threaded rod, 109-Drive motor, 110-Drive shaft, 111-Connecting frame, 112-Mounting ring, 113-Separation cylinder, 114-Support ring, 115-Support frame, 116-Rotating roller, 117-Pulley, 118-Slide groove. Detailed Implementation

[0019] Please see Figures 1 to 5 ,in, Figure 1 This is a schematic diagram of the separation and purification equipment of this utility model. Figure 2This is a cross-sectional view of the separation and purification equipment of this utility model. Figure 3 This is a schematic diagram of the structure below the cover plate of this utility model. Figure 4 This is a schematic diagram of the internal structure of the can in this utility model. Figure 5 This is the utility model Figure 4 Enlarged view of the local structure at point A.

[0020] This utility model provides a separation and purification device, including a tank 101 and a separation mechanism. The separation mechanism includes a cover plate 104, a funnel 105, a valve 106, a support assembly, an internally threaded cylinder 102, an externally threaded cylinder 103, a drive assembly, a mounting ring 112, a centrifuge cylinder, a threaded rod 108, and a mounting base 107. The drive assembly includes a drive motor 109, a drive shaft 110, and a connecting frame 111. The support assembly includes a support ring 114 and multiple sliding components. The sliding components include a support frame 115, a rotating roller 116, and a pulley 117. The mounting ring 112 has a sliding groove 118. The aforementioned solution solves the problem that the device needs to be thoroughly cleaned after separating and purifying pharmaceutical intermediate liquids to ensure that no liquid residue remains in the device. However, in the prior art, the tank 101 is difficult to open, and cleaning inside the tank 101 is relatively difficult, resulting in low practicality of the device.

[0021] In this embodiment, the internally threaded cylinder 102 is fixedly connected to the tank body 101 and located above the tank body 101; the externally threaded cylinder 103 is fixedly connected to the cover plate 104 and located below the cover plate 104; the internally threaded cylinder 102 is threadedly connected to the externally threaded cylinder 103 and located inside the externally threaded cylinder 103; the drive assembly is disposed on the cover plate 104; the mounting ring 112 is disposed on the output end of the drive assembly; the centrifuge cylinder is fixedly connected to the mounting ring 112 and located inside the mounting ring 112; the mounting base 107 is fixedly connected to one end of the internally threaded cylinder 102 and located inside the tank body 101; the threaded rod 108 is threadedly connected to the cover plate 104 and extends into the mounting base 107. When using this device to separate and purify pharmaceutical intermediates, the pharmaceutical intermediates are poured into the tank body 101, and a portion of the pharmaceutical intermediates passes through the separation cylinder 113. Then, the drive assembly is controlled to rotate the mounting ring 112 and the separating cylinder 113. At this time, one end of the threaded rod 108 is inserted into the mounting base 107 to ensure that the cover plate 104 will not fall off the tank body 101 when the separating cylinder 113 rotates. The rotating separating cylinder 113 centrifugally separates the pharmaceutical intermediate from the separating cylinder 113, thereby completing the separation of the pharmaceutical intermediate. When cleaning the components in the tank body 101, the threaded rod 108 is rotated to make the threaded rod 108 leave the mounting base 107. Then, the cover plate 104 and the external threaded cylinder 103 are rotated to separate the internal threaded cylinder 102 from the external threaded cylinder 103. Then, the cover plate 104 is pulled upward to make the mounting ring 112 and the separating cylinder 113 leave the tank body 101, so that the operator can clean the tank body 101 and the separating cylinder 113, thereby improving the practicality of the device.

[0022] Furthermore, the drive motor 109 is fixedly connected to the cover plate 104, the drive shaft 110 is fixedly connected to the output end of the drive motor 109 and extends into the tank body 101, the connecting frame 111 is fixedly connected to one end of the drive shaft 110, and the mounting ring 112 is fixedly connected to the connecting frame 111.

[0023] In this embodiment, when using the device to separate and purify pharmaceutical intermediates, the pharmaceutical intermediates are poured into the tank 101, and a portion of the pharmaceutical intermediates pass through the separation cylinder 113. Then, the drive motor 109 is started, which drives the drive shaft 110 and the connecting frame 111 to rotate. The connecting frame 111 drives the mounting ring 112 and the separation cylinder 113 to rotate. At this time, one end of the threaded rod 108 is inserted into the mounting base 107 to ensure that the cover plate 104 will not fall off the tank 101 when the separation cylinder 113 rotates. The separation cylinder 113 rotates and centrifugally separates the pharmaceutical intermediates from the separation cylinder 113.

[0024] Furthermore, the funnel 105 is fixedly connected to the tank 101 and is located below the tank 101, and the valve 106 is disposed on the funnel 105.

[0025] In this embodiment, the funnel 105 is designed to collect the separated intermediates, and the valve 106 is opened when the intermediates are removed.

[0026] Furthermore, the support assembly is disposed inside the tank 101, the support ring 114 is fixedly connected to the tank 101 and located below the mounting ring 112, and a plurality of the sliding kits are disposed on the support ring 114.

[0027] Furthermore, the support frame 115 is fixedly connected to the support ring 114 and is located above the support ring 114. The rotating roller 116 is rotatably connected to the pulley 117 and the support frame 115, and the pulley 117 is located inside the support frame 115. One end of the pulley 117 is slidably connected to the mounting ring 112 and is located inside the groove 118.

[0028] In this embodiment, when using this device to separate and purify pharmaceutical intermediates, the pharmaceutical intermediates are poured into the tank 101, and a portion of the pharmaceutical intermediates pass through the separation cylinder 113. Then, the drive motor 109 is started, which drives the drive shaft 110 and the connecting frame 111 to rotate. The connecting frame 111 drives the mounting ring 112 and the separation cylinder 113 to rotate. At this time, one end of the threaded rod 108 is inserted into the mounting base 107 to ensure that the cover plate 104 does not fall off the tank 101 when the separation cylinder 113 rotates. The separation cylinder 113 rotates and centrifugally separates the pharmaceutical intermediates from the separation cylinder 113. When the drive motor 109 drives the separation cylinder 113 to rotate, multiple pulleys 117 slide below the mounting ring 112. The multiple pulleys 117 support the mounting ring 112 and the separation cylinder 113 and limit and guide the rotation of the separation cylinder 113, thereby improving the structural stability of the device.

[0029] When using this invention to separate and purify pharmaceutical intermediates, the pharmaceutical intermediates are poured into the tank 101, and a portion of the pharmaceutical intermediates passes through the separation cylinder 113. Then, the drive motor 109 is started, which drives the drive shaft 110 and the connecting frame 111 to rotate. The connecting frame 111 drives the mounting ring 112 and the separation cylinder 113 to rotate. At this time, one end of the threaded rod 108 is inserted into the mounting base 107 to ensure that the cover plate 104 will not detach from the tank 101 when the separation cylinder 113 rotates. The pharmaceutical intermediates are centrifuged and separated from the separation cylinder 113. When cleaning the components inside the tank 101, the threaded rod 108 is rotated to move it away from the mounting base 107. Then, the cover plate 104 and the external threaded cylinder 103 are rotated to separate the internal threaded cylinder 102 from the external threaded cylinder 103. Finally, the cover plate 104 is pulled upward to move the mounting ring 112 and the separation cylinder 113 away from the tank 101, so that the operator can clean the tank 101 and the separation cylinder 113, thereby improving the practicality of the device.

[0030] The above-disclosed embodiments are merely preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art will understand that all or part of the processes for implementing the above embodiments, and equivalent variations made in accordance with the claims of this application, still fall within the scope of this application.

Claims

1. A separation and purification device comprising a tank body, characterized in that, further comprising a separation mechanism, the separation mechanism comprising a cover plate, an inner threaded cylinder, an outer threaded cylinder, a driving assembly, a mounting ring, a centrifugal cylinder, a threaded rod and a mounting seat, the inner threaded cylinder is fixedly connected with the tank body and located above the tank body, the outer threaded cylinder is fixedly connected with the cover plate and located below the cover plate, the inner threaded cylinder is threadedly connected with the outer threaded cylinder and located in the outer threaded cylinder, the driving assembly is arranged on the cover plate, the mounting ring is arranged on the output end of the driving assembly, the centrifugal cylinder is fixedly connected with the mounting ring and located in the mounting ring, the mounting seat is fixedly connected with one end of the inner threaded cylinder and located in the tank body, and the threaded rod is threadedly connected with the cover plate and extends into the mounting seat.

2. The separation and purification device according to claim 1, characterized in that, the driving assembly comprises a driving motor, a driving shaft and a connecting frame, the driving motor is fixedly connected with the cover plate, the driving shaft is fixedly connected with the output end of the driving motor and extends into the tank body, and the connecting frame is fixedly connected with one end of the driving shaft, and the mounting ring is fixedly connected with the connecting frame.

3. The separation and purification device according to claim 2, characterized in that, the separation mechanism further comprises a funnel and a valve, the funnel is fixedly connected with the tank body and located below the tank body, and the valve is arranged on the funnel.

4. The separation and purification device according to claim 3, characterized in that, the separation mechanism further comprises a supporting assembly, the supporting assembly comprising a supporting ring and a plurality of sliding sleeves, the supporting assembly is arranged in the tank body, the supporting ring is fixedly connected with the tank body and located below the mounting ring, and a plurality of the sliding sleeves are arranged on the supporting ring.

5. The separation and purification device according to claim 4, characterized in that, the sliding sleeve comprises a supporting frame, a rotating roller and a pulley, the mounting ring has a sliding groove, the supporting frame is fixedly connected with the supporting ring and located above the supporting ring, the rotating roller is rotatably connected with the pulley and the supporting frame, the pulley is located in the supporting frame, and one end of the pulley is slidably connected with the mounting ring and located in the sliding groove.

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