Probiotic encapsulation structures with bile sequestration function
By designing a composite structure consisting of a lower column, a fixing ring, a fixing column, an upper column, and an isolation mechanism, the problem of unstable fixation of the probiotic encapsulation structure during long-term storage was solved, achieving stable transport of probiotics in the gastric acid environment and bile isolation.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- HAIKOU BIHUO INVESTMENT CO LTD
- Filing Date
- 2025-07-28
- Publication Date
- 2026-06-26
AI Technical Summary
The existing probiotic encapsulation structure has a loosening fixation mechanism during long-term storage, which causes the probiotics to penetrate the gastric acid environment and become unstable.
It adopts a composite structure consisting of a lower column, a fixing ring, a fixing column, an upper column, and an isolation mechanism, which are connected by bolts and nuts. Combined with spring and hydrophobic mesh design, it achieves stable encapsulation of probiotics and bile isolation.
It improves the stability of probiotics during transportation, prevents gastric acid penetration, ensures that probiotics do not leak in the gastrointestinal environment, and achieves effective bile isolation and buffering effects.
Smart Images
Figure CN224410134U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of probiotic technology, and in particular to a probiotic encapsulation structure with bile isolation function. Background Technology
[0002] Probiotics are a class of live microorganisms that are beneficial to the host's health. They mainly colonize the human gut and reproductive system and exert various positive effects by regulating the balance of gut microbiota. They can inhibit the overgrowth of harmful bacteria, promote intestinal peristalsis, and help improve intestinal problems such as indigestion, constipation, and diarrhea. They can also enhance the intestinal mucosal barrier function and indirectly improve the body's immunity. Common probiotics include Bifidobacteria and Lactobacillus, which are widely found in yogurt and kimchi, and can also be obtained through supplements. However, the effects of probiotics are strain-specific and vary from person to person. Different strains may have different effects, and their efficacy can be affected by dosage, method of administration, and the state of the original gut microbiota. In addition, not everyone needs to supplement with probiotics. Healthy people can usually maintain the natural balance of gut microbiota through a balanced diet. However, for those with intestinal dysfunction or after taking antibiotics, appropriate supplementation under the guidance of a doctor may be more beneficial for the recovery of gut health.
[0003] Probiotic encapsulation structures with bile-isolating functions are protective systems designed to address the vulnerability of probiotics to intestinal bile. Their core principle is to construct a physical barrier using special materials, reducing direct contact between probiotics and high-concentration bile as they pass through the upper small intestine. However, without a stable fixation mechanism, bile can seep into the probiotics through the gaps in the encapsulation material. With technological advancements, fixation mechanisms have emerged as crucial designs to stably confine probiotics within the encapsulation material. Their core function is to prevent leakage during encapsulation or premature release before reaching the intestines. These mechanisms typically achieve fixation through chemical bonding, physical entanglement, or spatial grid structures between materials. For example, the cross-linking reaction of sodium alginate and calcium ions can form a three-dimensional network structure, encapsulating probiotics within the grid pores, restricting their free movement, and providing a physical barrier against bile erosion. However, such fixation mechanisms can loosen over prolonged storage, leading to instability and allowing gastric acid to penetrate during gastrointestinal passage. Utility Model Content
[0004] To overcome the above shortcomings, this utility model provides a probiotic encapsulation structure with bile isolation function, which aims to improve the problem that the fixation mechanism in the prior art will loosen during long-term storage, resulting in unstable fixation and allowing gastric acid to penetrate when passing through the gastrointestinal tract.
[0005] To achieve the above objectives, this utility model adopts the following technical solution: a probiotic encapsulation structure with bile isolation function, comprising a lower column, a fixing ring fixedly connected to the top of the lower column, multiple circular holes II being formed on the outer wall of the fixing ring, a fixing post slidably connected to the inner wall of the circular holes II, a spring II rotatably connected to the outer wall of the fixing post, an upper column slidably connected to the outer wall of the fixing post, an upper ring fixedly connected to the outer wall of the upper column, a bottom ring fixedly connected to the upper end of the outer wall of the lower column, a bolt threadedly connected to the outer wall of the upper ring, a nut threadedly connected to the outer wall of the bolt, and an isolation mechanism provided inside the lower column for buffering and blocking bile.
[0006] As a further description of the above technical solution:
[0007] The isolation mechanism includes a connecting column, the bottom of which is fixedly connected to the top of the lower column. A pressure plate is slidably connected to the outer wall of the connecting column. A circular hole is opened near the middle of the top of the pressure plate. A spring is slidably connected to the outer wall of the connecting column. A hydrophobic mesh is fixedly connected to the inner wall of the lower column. Multiple hydrophobic holes are opened on the outer wall of the hydrophobic mesh.
[0008] As a further description of the above technical solution:
[0009] An elastic ring is fixedly connected to the outer wall of the upper column near the middle, and the elastic ring is used for support.
[0010] As a further description of the above technical solution:
[0011] Multiple support rods are fixedly connected to the bottom of each elastic ring near its edge, and these support rods are used for limiting support.
[0012] As a further description of the above technical solution:
[0013] The top of the support rod is slidably connected to a fixing sleeve, and the adjacent fixing sleeves are slidably connected to the outer wall of the upper column. The fixing sleeves are used for disassembly.
[0014] As a further description of the above technical solution:
[0015] A spring three is slidably connected to the bottom of the outer wall of the support rod, and the spring three is used to provide elastic support.
[0016] As a further description of the above technical solution:
[0017] A retaining ring is fixedly connected to the outer wall of the support rod near the middle. The top of the retaining ring is slidably connected to the bottom of the bottom ring, and the retaining ring is used for support.
[0018] As a further description of the above technical solution:
[0019] The outer wall of the lower column is fixedly connected to an elastic ring II, and the top of the elastic ring II is fixedly connected to the bottom of the support rod.
[0020] This utility model has the following beneficial effects:
[0021] 1. In this utility model, the probiotics to be encapsulated are first placed into the lower column, and then the upper column is installed. When the upper column moves to the surface of the fixed column, it will squeeze the fixed column. At this time, the fixed column will move inward and squeeze the second spring to deform it. When the upper column is locked, the fixed column will spring back under the restoring action of the second spring. At this time, the fixed column will spring back along the second circular hole on the fixed ring and lock back onto the surface of the upper column. At the same time, the bolt is unscrewed so that the bolt and nut lock the bottom ring and the upper ring, which makes the encapsulation more stable and prevents it from easily loosening.
[0022] 2. In this utility model, when shaking occurs, the probiotics inside will squeeze the pressure plate. At this time, the circular hole on the pressure plate will shake along the outer wall of the connecting column, while squeezing the spring and deforming it, which plays a buffering role. When bile is needed, the hydrophobic holes on the hydrophobic mesh can only drain water from the inside and cannot absorb external liquid. At this time, bile can be isolated from the outside, thus achieving the function of buffering during transportation and isolating bile. Attached Figure Description
[0023] Figure 1 This is a front perspective view of the probiotic encapsulation structure with bile isolation function proposed in this utility model.
[0024] Figure 2 This is a partial structural breakdown of the upper column of the probiotic encapsulation structure with bile isolation function proposed in this utility model.
[0025] Figure 3 A partial structural breakdown diagram of the circular pores of the probiotic encapsulation structure with bile isolation function proposed in this utility model.
[0026] Figure 4 This is a partial structural breakdown of the bottom ring of the probiotic encapsulation structure with bile isolation function proposed in this utility model;
[0027] Figure 5 This is a partial structural breakdown of the hydrophobic mesh of the probiotic encapsulation structure with bile isolation function proposed in this utility model.
[0028] Legend:
[0029] 1. Lower column; 2. Isolation mechanism; 201. Connecting column; 202. Pressure plate; 203. Circular hole one; 204. Spring one; 205. Drainage net; 206. Drainage hole; 3. Fixing ring; 4. Circular hole two; 5. Fixing column; 6. Spring two; 7. Bottom ring; 8. Upper ring; 9. Bolt; 10. Nut; 11. Upper column; 12. Elastic ring one; 13. Fixing sleeve; 14. Support rod; 15. Retaining ring; 16. Spring three; 17. Elastic ring two. Detailed Implementation
[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0031] Please see the appendix Figure 1 Appendix Figure 4 and attached Figure 5 An embodiment of this utility model provides a probiotic encapsulation structure with bile isolation function, including a lower column 1, a fixing ring 3 fixedly connected to the top of the lower column 1, multiple circular holes 4 opened on the outer wall of the fixing ring 3, a fixing column 5 slidably connected to the inner wall of the circular holes 4, a spring 6 rotatably connected to the outer wall of the fixing column 5, an upper column 11 slidably connected to the outer wall of the fixing column 5, an upper ring 8 fixedly connected to the outer wall of the upper column 11, a bottom ring 7 fixedly connected to the upper end of the outer wall of the lower column 1, a bolt 9 threadedly connected to the outer wall of the upper ring 8, a nut 10 threadedly connected to the outer wall of the bolt 9, and an isolation mechanism 2 provided inside the lower column 1, the isolation mechanism 2 being used for buffering and blocking bile;
[0032] Specifically, the structure includes a lower column 1, the top of which is securely connected to a fixing ring 3. Multiple circular holes 4 are evenly distributed on the outer wall of the fixing ring 3. A fixing column 5 is slidably connected to the inner wall of these circular holes 4. A spring 6 is rotatably connected to the outer wall of the fixing column 5, providing elasticity when the fixing column 5 rotates. An upper column 11 is also slidably connected to the outer wall of the fixing column 5, and an upper ring 8 is fixedly connected to its outer wall. Furthermore, a bottom ring 7 is fixedly connected to the upper part of the outer wall of the lower column 1. A bolt 9 is threadedly connected to the outer wall of the upper ring 8, and a nut 10 is further threadedly connected to the outer wall of the bolt 9. Inside the lower column 1, an isolation mechanism 2 is provided. The main function of the isolation mechanism 2 is to provide buffering and, when necessary, to block the flow of bile, ensuring the stability and functionality of the entire structure.
[0033] Please see the appendix Figure 1 Appendix Figure 2 and attached Figure 3 The isolation mechanism 2 includes a connecting column 201, the bottom of which is fixedly connected to the top of the lower column 1. A pressure plate 202 is slidably connected to the outer wall of the connecting column 201. A circular hole 203 is opened near the middle of the top of the pressure plate 202. A spring 204 is slidably connected to the outer wall of the connecting column 201. A hydrophobic mesh 205 is fixedly connected to the inner wall of the lower column 1. A plurality of hydrophobic holes 206 are opened on the outer wall of the hydrophobic mesh 205.
[0034] Specifically, the isolation mechanism 2 is a composite structure composed of multiple components, including a connecting column 201. The bottom of the connecting column 201 is tightly connected to the top of the lower column 1 through a fixed connection, ensuring the stability and reliability of the entire structure. A sliding pressure plate 202 is provided on the outer wall of the connecting column 201. This pressure plate 202 can move freely on the connecting column 201 to adapt to different usage requirements. A circular hole 203 is specially provided near the center of the top of the pressure plate 202. The presence of the circular hole 203 allows the pressure plate 201 to... The functions of the 2 are more diversified. In addition, a spring 204 is slidably connected to the outer wall of the connecting column 201. This spring 204 can extend and retract on the connecting column 201 to provide the necessary elastic support for the entire isolation mechanism 2. A hydrophobic mesh 205 is fixedly connected to the inner wall of the lower column 1. The main function of this hydrophobic mesh 205 is to prevent water from entering the interior of the mechanism and protect the internal components from damage. Multiple hydrophobic holes 206 are evenly opened on the outer wall of the hydrophobic mesh 205. These hydrophobic holes 206 can effectively drain water and ensure that the function of the hydrophobic mesh 205 is fully utilized.
[0035] Please see the appendix Figure 1 Appendix Figure 2 and attached Figure 4 An elastic ring 12 is fixedly connected to the outer wall of the upper column 11 near the middle. The elastic ring 12 is used for support. Multiple support rods 14 are fixedly connected to the bottom of the elastic ring 12 near the edge. The support rods 14 are used for limiting support. A fixing sleeve 13 is slidably connected to the top of the support rod 14. The multiple fixing sleeves 13 are slidably connected to the outer wall of the upper column 11 between adjacent ones. The fixing sleeves 13 are used for disassembly.
[0036] Specifically, an elastic ring 12 is fixedly connected to the upper column 11 near the middle of its outer wall. The main function of the elastic ring 12 is to provide support and ensure the stability and reliability of the entire structure. At the bottom of the elastic ring 12, near its edge, multiple support rods 14 are evenly fixedly connected. The main function of these support rods 14 is to provide limiting support and prevent displacement and offset of the structure during movement. The top of each support rod 14 is connected to a fixed sleeve 13 by a sliding connection. The multiple fixed sleeves 13 are adjacent to each other and they are also in contact with the outer wall of the upper column 11 by a sliding connection. The design of these fixed sleeves 13 makes them easy to disassemble for maintenance and replacement, which not only improves the overall stability and functionality but also increases the flexibility and convenience of use.
[0037] Please see the appendix Figure 1 Appendix Figure 2 and attached Figure 5 A spring 16 is slidably connected to the bottom of the outer wall of the support rod 14. The spring 16 is used to provide elastic support. A retaining ring 15 is fixedly connected to the outer wall of the support rod 14 near the middle. The top of the retaining ring 15 is slidably connected to the bottom of the bottom ring 7. The retaining ring 15 is used for support. An elastic ring 17 is fixedly connected to the outer wall of the lower column 1. The top of the elastic ring 17 is fixedly connected to the bottom of the support rod 14.
[0038] Specifically, a spring 16 is installed at the bottom of the outer wall of the support rod 14 via a sliding connection. The main function of the spring 16 is to provide necessary elastic support to ensure the stability and flexibility of the entire structure. The spring 16 plays a buffering and supporting role at the bottom of the outer wall of the support rod 14. In addition, a retaining ring 15 is fixedly connected to the outer wall of the support rod 14 near the middle. The top of the retaining ring 15 is connected to the bottom of the bottom ring 7 via a sliding connection. The main function of the retaining ring 15 is to provide additional support force to ensure that the entire device remains stable during operation. Furthermore, an elastic ring 17 is fixedly connected to the outer wall of the lower column 1. The top of the elastic ring 17 is tightly connected to the bottom of the support rod 14 via a fixed connection. The presence of the elastic ring 17 further enhances the stability and support effect of the entire structure.
[0039] Working principle: First, the probiotics to be encapsulated are placed in the lower column 1. Then, the upper column 11 is installed. When the upper column 11 moves to the surface of the fixed column 5, it will squeeze the fixed column 5. At this time, the fixed column 5 will move inward and squeeze the second spring 6 to deform it. When the upper column 11 is locked, the fixed column 5 will spring back under the restoring action of the second spring 6. At this time, the fixed column 5 will spring back along the circular hole 4 on the fixed ring 3 and lock back onto the surface of the upper column 11. At the same time, the bolt 9 is unscrewed, so that the bolt 9 and the nut 10 lock the bottom ring 7 and the upper ring 8. When it is time to consume, the bottom ring 7, the upper ring 8 and the bolt 9 are removed for consumption. This achieves a more stable encapsulation and prevents it from easily loosening.
[0040] When shaking occurs, the probiotics inside will squeeze the pressure plate 202. At this time, the circular holes 203 on the pressure plate 202 will shake along the outer wall of the connecting column 201, while squeezing the spring 204, causing it to deform and playing a buffering role. When bile is needed, the hydrophobic holes 206 on the hydrophobic mesh 205 can only drain water from the inside and cannot absorb external liquids. At this time, bile can be isolated from the outside, thus achieving the function of buffering during transportation and isolating bile.
[0041] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A probiotic encapsulation structure with bile isolation function, comprising a lower column (1), characterized in that: The top of the lower column (1) is fixedly connected to a fixing ring (3). The outer wall of the fixing ring (3) is provided with multiple circular holes (4). The inner wall of the circular holes (4) is slidably connected to a fixing column (5). The outer wall of the fixing column (5) is rotatably connected to a spring (6). The outer wall of the fixing column (5) is slidably connected to an upper column (11). The outer wall of the upper column (11) is fixedly connected to an upper ring (8). The upper end of the outer wall of the lower column (1) is fixedly connected to a bottom ring (7). The outer wall of the upper ring (8) is threadedly connected to a bolt (9). The outer wall of the bolt (9) is threadedly connected to a nut (10). The interior of the lower column (1) is provided with an isolation mechanism (2). The isolation mechanism (2) is used for buffering and blocking bile.
2. The probiotic encapsulation structure with bile isolation function according to claim 1, characterized in that: The isolation mechanism (2) includes a connecting column (201), the bottom of which is fixedly connected to the top of the lower column (1), a pressure plate (202) is slidably connected to the outer wall of the connecting column (201), a circular hole (203) is opened near the middle of the top of the pressure plate (202), a spring (204) is slidably connected to the outer wall of the connecting column (201), a hydrophobic mesh (205) is fixedly connected to the inner wall of the lower column (1), and a plurality of hydrophobic holes (206) are opened on the outer wall of the hydrophobic mesh (205).
3. The probiotic encapsulation structure with bile isolation function according to claim 1, characterized in that: An elastic ring (12) is fixedly connected to the outer wall of the upper column (11) near the middle, and the elastic ring (12) is used for support.
4. The probiotic encapsulation structure with bile isolation function according to claim 3, characterized in that: Multiple support rods (14) are fixedly connected to the bottom of the elastic ring (12) near the edge. The support rods (14) are used for limiting support.
5. The probiotic encapsulation structure with bile isolation function according to claim 4, characterized in that: The top of the support rod (14) is slidably connected to a fixing sleeve (13), and the adjacent fixing sleeves (13) are slidably connected to the outer wall of the upper column (11). The fixing sleeves (13) are used for disassembly.
6. The probiotic encapsulation structure with bile isolation function according to claim 4, characterized in that: A spring three (16) is slidably connected to the bottom of the outer wall of the support rod (14), and the spring three (16) is used to provide elastic support.
7. The probiotic encapsulation structure with bile isolation function according to claim 5, characterized in that: A retaining ring (15) is fixedly connected to the outer wall of the support rod (14) near the middle. The top of the retaining ring (15) is slidably connected to the bottom of the bottom ring (7). The retaining ring (15) is used for support.
8. The probiotic encapsulation structure with bile isolation function according to claim 1, characterized in that: The outer wall of the lower column (1) is fixedly connected to an elastic ring (17), and the top of the elastic ring (17) is fixedly connected to the bottom of the support rod (14).