Blood genetic metabolic spectrum dried blood smear drop auxiliary device

By designing a blood genetic metabolic spectrum stem blood smear dripping auxiliary device, and using a support and limiting plate assembly to precisely control the dripping volume, the problem of inaccurate dripping in existing technologies is solved, and the accuracy of detection is improved.

CN224422921UActive Publication Date: 2026-06-30HANGZHOU CHILDRENS HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
HANGZHOU CHILDRENS HOSPITAL
Filing Date
2025-06-10
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

In existing technologies, the dried blood paper method cannot accurately control the amount of blood dropped, causing the blood drop to exceed the paper's range, resulting in excessively high local concentrations and affecting the accuracy of the test results.

Method used

A blood genetic metabolic spectrum stem blood smear dripping auxiliary device was designed, including a support, a sleeve, a limiting plate assembly and a lifting and adjusting mechanism. The limiting plate assembly restricts the movement distance of the syringe core rod, and the lifting and adjusting mechanism adjusts the position of the limiting plate to achieve precise control of the dripping volume.

Benefits of technology

It enables precise control of the amount of blood dripped, preventing excessive blood droplets and improving the accuracy of the test.

✦ Generated by Eureka AI based on patent content.

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    Figure CN224422921U_ABST
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Abstract

This utility model relates to the field of blood dripping device technology, and discloses a blood genetic metabolic spectrum dried blood smear blood dripping auxiliary device, including a support, on which a sleeve is installed. A receiving groove is opened on one side of the sleeve for placing the barrel of a syringe. A bleeding head is installed at the bottom of the sleeve. After the limiting plate assembly is moved away from the top of the receiving groove, the barrel of the syringe is placed into the receiving groove, and then the limiting plate assembly is rotated to limit the movement distance of the core rod. At this time, the core rod of the syringe can be moved to squeeze the blood in the barrel, so that the blood drips onto the cardboard through the bleeding head. The limiting plate assembly can prevent excessive blood from dripping, increasing the accuracy of detection. Furthermore, the lifting and adjusting mechanism can drive the connecting plate assembly and the limiting plate assembly to move, thereby adjusting the position of the limiting plate assembly to drip different amounts of blood, solving the problem of not being able to accurately control the blood dripping volume in the prior art.
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Description

Technical Field

[0001] This utility model relates to the field of blood-dropping device technology, and in particular to a blood genetic metabolic spectrum stem blood droplet blood-dropping auxiliary device. Background Technology

[0002] Metabolomics is the study of the composition and dynamic changes of small molecule metabolites (such as amino acids, organic acids, carbohydrates, and lipids) in organisms. Inborn Errors of Metabolism (IEM) are a group of diseases caused by gene mutations leading to defects in the function of metabolic enzymes or transport proteins, often resulting in metabolic pathway disorders, accumulation of toxic intermediates, or deficiency of essential metabolites. Early diagnosis is crucial for improving prognosis, and blood genetic metabolic profiling technology provides an efficient tool for the screening and diagnosis of IEM through high-throughput analysis of metabolites in the blood.

[0003] In existing technologies, the dried blood paper method can be used to screen for genetic metabolic diseases. This method involves collecting whole blood samples on a piece of paper. Compared with traditional methods, it has certain advantages in blood collection, requiring less blood and making the collection process more convenient. However, in existing technologies, it is difficult to accurately control the amount of blood dropped onto the paper. This can easily cause the blood drop to exceed the dotted line range of the paper, resulting in excessively high local blood concentrations. This can prevent effective extraction and analysis in some areas, potentially leading to inaccurate test results. Utility Model Content

[0004] The purpose of this invention is to solve the problems existing in the prior art by proposing a blood genetic metabolic spectrum dried blood drop auxiliary device.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A blood genetic metabolic spectrum dried blood smear blood drop auxiliary device includes a support, on which a sleeve is mounted, and a receiving groove is provided on one side of the sleeve for placing the cylinder of a syringe;

[0007] The bracket is equipped with two connecting plate assemblies and two limiting plate assemblies to limit the distance the core rod can move.

[0008] The two limiting plate assemblies are respectively rotatably mounted on the corresponding connecting plate assemblies via rotating assemblies, which are used to remove the limiting plate assemblies to facilitate the placement of the cylinder body;

[0009] The bracket is also equipped with a lifting and adjusting mechanism for driving the connecting plate assembly and the limiting plate assembly to move.

[0010] Preferably, the connecting plate assembly includes two connecting plate bodies, the limiting plate assembly includes a limiting plate body, the rotating component is a damping rotating shaft, the limiting plate body is mounted above the connecting plate body through damping rotation, and the two connecting plate bodies are arranged at the drive end of the lifting and adjusting mechanism.

[0011] Preferably, the two limiting plate bodies are arranged symmetrically.

[0012] Preferably, the lifting and adjusting mechanism includes two slides formed on the bracket, a threaded rod rotatably disposed in one of the slides, and a guide rod fixedly disposed in the other slide. The two connecting plate bodies are slidably disposed in their respective slides. The threaded rod movably passes through the connecting plate body in the corresponding slide and is threadedly connected to the connecting plate body. The guide rod movably passes through the connecting plate body in the corresponding slide. The two connecting plate bodies are connected by a connecting rod. A knob assembly is provided on one side of the bracket for driving the threaded rod to rotate.

[0013] Preferably, the knob assembly includes a mounting groove and a knob body formed on the bracket. A first bevel gear is rotatably disposed in the mounting groove. One side of the first bevel gear is connected to a threaded rod. A rotating rod is rotatably disposed in the mounting groove. A second bevel gear is mounted on one end of the rotating rod. The second bevel gear meshes with the first bevel gear. The other end of the rotating rod extends movably through the bracket to the outside of the bracket and is connected to the knob body.

[0014] Preferably, the bracket has openings on both sides above it, and the two openings are respectively connected to corresponding sliding grooves. The bracket is provided with a bleeding measurement scale, and an indicator arrow is provided on one side of the connecting plate body. The indicator arrow corresponds to the position of the opening and the bleeding measurement scale.

[0015] Preferably, both the bracket and the sleeve are made of polypropylene.

[0016] Compared with the prior art, the beneficial effects of this utility model are:

[0017] This invention, through its designed bracket, allows the cardstock to be placed on a table first, then the bracket to be supported above the cardstock. The limiting plate assembly is then rotated via a rotating component, moving it away from the top of the receiving groove. The syringe barrel is then placed into the receiving groove, and the limiting plate assembly is rotated again to restrict the movement distance of the syringe plunger. This allows the syringe plunger to be moved to squeeze blood from the barrel, causing it to drip onto the cardstock through the syringe tip. The limiting plate assembly prevents excessive blood dripping, increasing detection accuracy. Furthermore, the designed lifting and adjusting mechanism allows the connecting plate assembly and the limiting plate assembly to be moved, adjusting the position of the limiting plate assembly to drip different amounts of blood, thus solving the problem of inaccurate blood measurement in existing technologies. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall blood genetic metabolic spectrum dried blood smear dripping auxiliary device proposed in this utility model;

[0019] Figure 2 This is a schematic diagram of the mounting groove for the blood genetic metabolic spectrum dried blood smear dripping auxiliary device proposed in this utility model;

[0020] Figure 3 This is a schematic diagram of the needle seat groove of the blood genetic metabolic spectrum dried blood smear dripping auxiliary device proposed in this utility model;

[0021] Figure 4 This is a schematic diagram of the groove of the blood genetic metabolic spectrum dry blood drop auxiliary device proposed in this utility model.

[0022] In the diagram: 1. Bracket; 2. Sleeve; 3. Receiving groove; 4. Syringe head; 5. Needle seat groove; 6. Connecting plate body; 7. Limiting plate body; 8. Damping shaft; 9. Slide groove; 10. Threaded rod; 11. Guide rod; 12. Mounting groove; 13. Knob body; 14. First bevel gear; 15. Second bevel gear; 16. Rotating rod; 17. Connecting rod; 18. Opening; 19. Bleeding measurement scale; 20. Indicating arrow. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0024] Reference Figures 1 to 4 A blood genetic metabolic spectrum stem blood smear blood drop auxiliary device includes a support 1, a sleeve 2 is installed on the support 1, and a receiving groove 3 is opened on one side of the sleeve 2 for placing the cylinder of the syringe.

[0025] The syringe is equipped with a syringe head 4 at the bottom for blood drainage;

[0026] The support 1 is provided with two connecting plate assemblies and two limiting plate assemblies to limit the distance the core rod moves. The end of the core rod located inside the syringe has a piston, and blood can be squeezed out by pushing the core rod.

[0027] The two limiting plate assemblies are respectively rotatably mounted on the corresponding connecting plate assemblies via rotating assemblies, which are used to remove the limiting plate assemblies to facilitate the placement of the cylinder body;

[0028] The bracket 1 is also equipped with a lifting and adjusting mechanism for driving the connecting plate assembly and the limiting plate assembly to move.

[0029] In use, the card is first placed on a table, then the bracket 1 is placed above the card. The limiting plate assembly is then rotated by the rotating component to move it away from the top of the receiving groove 3. The syringe barrel is then placed into the receiving groove 3, and the limiting plate assembly is rotated again to restrict the movement distance of the needle rod. At this point, the needle rod of the syringe can be moved to squeeze the blood inside the barrel, causing the blood to drip onto the card through the blood outlet. The limiting plate assembly prevents excessive blood from dripping, increasing the accuracy of the detection. Furthermore, the lifting and adjusting mechanism can move the connecting plate assembly and the limiting plate assembly to adjust the position of the limiting plate assembly, allowing for different amounts of blood to drip, thus solving the problem of accurately controlling the blood drip volume in existing technologies.

[0030] Furthermore, the bleeding head is a needle, and the receiving groove 3 has a needle seat groove 5. The bleeding head is connected to the needle seat groove 5. Through the needle seat groove 5, the needle seat of the syringe can be inserted into the needle seat groove 5. Then, the blood in the syringe is squeezed by the core rod, so that the blood drips through the needle seat groove 5 and the syringe head 4 onto the cardboard, thus completing the collection of blood samples.

[0031] Furthermore, the connecting plate assembly includes two connecting plate bodies 6, the limiting plate assembly includes a limiting plate body 7, and the rotating component is a damping rotating shaft 8. The limiting plate body 7 is mounted above the connecting plate body 6 via damping rotation. The two connecting plate bodies 6 are located at the drive end of the lifting and adjusting mechanism. Through the damping rotating shaft 8, the limiting plate body 7 can be rotated to adjust its position so that the syringe barrel can be inserted into the receiving groove 3. After insertion, the limiting plate body 7 is rotated to reset, thereby limiting the movement distance of the core rod.

[0032] Furthermore, the two limiting plate bodies 7 are symmetrically arranged. By symmetrically arranging the two limiting plate assemblies, the limiting plate assemblies can limit the two sides of the syringe core rod, thereby increasing the limiting effect.

[0033] Furthermore, the lifting and adjusting mechanism includes two grooves 9 formed on the bracket 1, a threaded rod 10 rotatably disposed in one of the grooves 9, and a guide rod 11 fixedly disposed in the other groove 9. The two connecting plate bodies 6 are slidably disposed in their respective grooves 9. The threaded rod 10 is threadedly connected to the connecting plate body 6 in the corresponding groove 9. The guide rod 11 is threadedly connected to the connecting plate body 6 in the corresponding groove 9. The two connecting plate bodies 6 are connected by a connecting rod 17. A knob assembly is provided on one side of the bracket 1 for driving the threaded rod 10 to rotate. The threaded rod 10 can be rotated by the knob assembly. The rotation of the threaded rod 10 can move the connecting plate body 6 in the groove 9. The connecting rod 17 can move the other connecting plate body 6 along the guide rod 11 when one connecting plate body 6 moves, so as to realize the synchronous adjustment of the two connecting plate bodies 6, adjust the position of the limiting plate body 7, limit the distance of movement of the core rod, and control the measurement of blood droplets.

[0034] Furthermore, the knob assembly includes a mounting groove 12 and a knob body 13 formed on the bracket 1. A first bevel gear 14 is rotatably disposed in the mounting groove 12. One side of the first bevel gear 14 is connected to the threaded rod 10. A rotating rod 16 is rotatably disposed in the mounting groove 12. A second bevel gear 15 is mounted on one end of the rotating rod 16. The second bevel gear 15 is meshed with the first bevel gear 14. The other end of the rotating rod 16 extends movably through the bracket 1 to the outside of the bracket 1 and is connected to the knob body 13. By rotating the knob body 13, the knob body 13 can be rotated, which drives the rotating rod 16 to rotate, thereby driving the second bevel gear 15 to rotate, which in turn drives the first bevel gear 14 to rotate. The first bevel gear 14 drives the threaded rod 10 to rotate, thereby driving the connecting plate body 6 to move within the slide groove 9.

[0035] Furthermore, openings 18 are provided on the upper sides of both sides of the bracket 1, and the two openings 18 are respectively connected to the corresponding sliding grooves 9. A bleeding measurement scale 19 is provided on the bracket 1, and an indicator arrow 20 is provided on one side of the connecting plate body 6. The indicator arrow 20 corresponds to the position of the openings 18 and the bleeding measurement scale 19. After adjusting the position of the connecting plate body 6 and the limiting plate body 7, the position of the indicator arrow 20 can be observed through the openings 18, so as to observe the position of the indicator arrow 20 on the bleeding measurement scale 19, so as to observe the amount of dripping blood and prevent excessive bleeding.

[0036] Furthermore, both the bracket 1 and the sleeve 2 are made of polypropylene. By using polypropylene as the material for the bracket 1 and the sleeve 2, the sleeve 2 and the bracket 1 have good chemical resistance, heat resistance and high strength.

[0037] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A blood genetic metabolic profile blood drop auxiliary device for dried blood spots, comprising a support (1), characterized in that: A sleeve (2) is installed on the bracket (1), and a receiving groove (3) is provided on one side of the sleeve (2) for placing the syringe body; The bracket (1) is provided with two connecting plate assemblies and two limiting plate assemblies to limit the distance the core rod moves; The two limiting plate assemblies are respectively rotatably mounted on the corresponding connecting plate assemblies via rotating assemblies, which are used to remove the limiting plate assemblies to facilitate the placement of the cylinder body; The bracket (1) is also equipped with a lifting adjustment mechanism for driving the connecting plate assembly and the limiting plate assembly to move.

2. The dried blood spot blood genetic metabolic profile blood drop assisting device according to claim 1, characterized in that: The connecting plate assembly includes two connecting plate bodies (6), the limiting plate assembly includes a limiting plate body (7), the rotating component is a damping rotating shaft (8), the limiting plate body (7) is mounted above the connecting plate body (6) by damping rotation, and the two connecting plate bodies (6) are set at the driving end of the lifting and adjusting mechanism.

3. The dried blood spot blood genetic metabolic profile blood drop assisting device according to claim 2, characterized in that: The two limiting plate bodies (7) are arranged symmetrically.

4. The dried blood spot blood genetic metabolic profile blood drop assisting device according to claim 3, characterized in that: The lifting and adjusting mechanism includes two slide grooves (9) on the bracket (1), a threaded rod (10) rotatably disposed in one of the slide grooves (9), and a guide rod (11) fixedly disposed in the other slide groove (9). The two connecting plate bodies (6) are slidably disposed in the corresponding slide grooves (9). The threaded rod (10) moves through the connecting plate body (6) in the corresponding slide groove (9) and is threadedly connected to the connecting plate body (6). The guide rod (11) moves through the connecting plate body (6) in the corresponding slide groove (9). The two connecting plate bodies (6) are connected by a connecting rod (17). A knob assembly is provided on one side of the bracket (1) for driving the threaded rod (10) to rotate.

5. The dried blood spot blood genetic metabolic profile blood drop assisting device according to claim 4, characterized in that: The knob assembly includes a mounting groove (12) and a knob body (13) on the bracket (1). A first bevel gear (14) is rotatably disposed in the mounting groove (12). One side of the first bevel gear (14) is connected to a threaded rod (10). A rotating rod (16) is rotatably disposed in the mounting groove (12). A second bevel gear (15) is installed at one end of the rotating rod (16). The second bevel gear (15) meshes with the first bevel gear (14). The other end of the rotating rod (16) extends movably through the bracket (1) to the outside of the bracket (1) and is connected to the knob body (13).

6. The blood genetic metabolic spectrum dried blood smear dripping auxiliary device according to claim 5, characterized in that: The bracket (1) has openings (18) on both sides above it. The two openings (18) are connected to the corresponding slides (9). The bracket (1) is equipped with a bleeding measurement scale (19). The connecting plate body (6) is equipped with an indicator arrow (20) on one side. The indicator arrow (20) corresponds to the position of the opening (18) and the bleeding measurement scale (19).

7. The blood genetic metabolic spectrum dried blood smear dripping auxiliary device according to claim 6, characterized in that: Both the bracket (1) and the sleeve (2) are made of polypropylene.