A drip-proof filling device for freeze-dried powder injections
By combining the output assembly consisting of a feed tube, an extrusion bladder, and a syringe with a leak-proof assembly consisting of a clamping frame and a clamping ring tube, the problem of drug leakage during the filling process of freeze-dried powder injections has been solved, achieving leak-free filling and improving production efficiency and product quality.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- ANHUI ZHONGLONG GUOCHUANG BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-09-05
- Publication Date
- 2026-06-30
AI Technical Summary
In the current process of filling lyophilized powder injections, leakage of the drug solution during filling intervals leads to contamination of vials and filling platforms, affecting production efficiency and the management of ingredients.
The output assembly consists of a feed tube, a squeezing bladder, and a needle tube. Combined with a clamping frame and a clamping ring tube, the leak-proof assembly uses steel balls to seal the squeezing bladder, achieving temporary storage and sealing of the liquid medicine during the filling interval and preventing liquid medicine leakage.
It effectively avoids leakage of the medicine during the filling interval, prevents contamination of vials and filling platform, and improves production efficiency and product quality.
Smart Images

Figure CN224427915U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of freeze-dried powder injection production equipment, specifically to a freeze-dried powder injection anti-drip filling equipment. Background Technology
[0002] The production process of lyophilized powder injections mainly includes steps such as drug preparation, filling, semi-stopping, freeze drying, full-stopping sealing, and quality inspection. During the filling process, liquid medication needs to be injected into vials. On existing production lines, a conveyor belt transports vials to the filling mechanism. The filling tube on the filling mechanism extends into the vial and begins to feed the medication. After filling, the syringe rises, and the conveyor belt moves the next vial below the syringe, which then repeats the filling process. Therefore, during the sequential filling of vials on the production line, there are filling gaps. During these gaps, although the control pump supplying the medication to the filling tube stops, a small amount of medication remains in the tube. This medication may drip down during the filling gap, contaminating the vials and filling platform. Contaminated vials and the filling platform require additional cleaning, affecting production efficiency and component management. To address this, this invention proposes an anti-drip filling device for lyophilized powder injections. Utility Model Content
[0003] The purpose of this invention is to provide a drip-proof filling device for freeze-dried powder injections in order to solve the above-mentioned problems.
[0004] This utility model achieves the above objectives through the following technical solutions:
[0005] This utility model provides a freeze-dried powder injection anti-drip filling equipment, including a chassis, a conveyor belt and a feeding box on the chassis, guardrails and photoelectric positioning sensors on both sides of the conveyor belt, a lifting frame and a telescopic rod for driving the lifting frame to rise and fall, and also includes a number of output components on the lifting frame and anti-leakage components corresponding to each output component.
[0006] The output component includes a feed tube, a squeezing bladder, and a needle tube connected sequentially from top to bottom. The squeezing bladder includes a bladder body and steel balls disposed within the bladder body.
[0007] The leak-proof assembly includes a clamping frame and a clamping ring tube fitted on the outside of the output assembly, as well as a vertical rod for supporting the clamping frame and the clamping ring tube. The clamping frame is used to squeeze the bladder from both sides, and the clamping ring tube is used to surround the squeeze bladder to cooperate with the steel ball to seal the squeeze bladder.
[0008] As a further optimization of this utility model, the output component also includes a material pump mounted on the lifting frame. The material pump is connected to the material supply box via a flexible hose, and the material conveying pipe is mounted on the material pump and connected to the material pump.
[0009] As a further optimization of this utility model, both the inlet and outlet of the capsule are provided with connecting pipes, and the steel ball is connected to the connecting pipes through a T-shaped connecting rod.
[0010] As a further optimization of this utility model, a clamping sleeve is provided at the output port of the capsule.
[0011] As a further optimization of this utility model, the connecting tube that connects with the needle tube is provided with a shielding membrane with a central slit.
[0012] As a further optimization of this utility model, it also includes a cleaning mechanism, which includes a manifold on the chassis and a suction head corresponding to the needle tube. The suction head is aligned with the needle tube and connected to the manifold. The manifold is provided with a ventilation pipe for connecting an external fan.
[0013] The beneficial effects of this utility model are as follows:
[0014] In this invention, a single unit consisting of a feed tube, a squeezing bladder, and a syringe replaces the traditional integrated filling tube. During the intermittent filling of continuously conveyed vials, a reverse suction effect is achieved through the cooperation of the clamping frame and the squeezing bladder, allowing the material in the syringe to be temporarily stored in the squeezing bladder. Subsequently, the squeezing bladder is sealed by the cooperation of the squeezing bladder and the clamping ring tube, preventing the material in the feed tube from seeping down. This comprehensively avoids the problem of material seeping down during the filling interval, which could lead to contamination of the vials or filling platform. Attached Figure Description
[0015] Figure 1 This is a schematic diagram of the overall appearance of the present utility model;
[0016] Figure 2 A schematic diagram showing the assembly of the lifting frame, output components, and leak-proof components;
[0017] Figure 3 This is a cross-sectional view of the compression bladder.
[0018] In the diagram: 1. Chassis; 2. Feeding box; 3. Lifting frame; 4. Feed pump; 5. Conveyor belt; 6. Guardrail; 7. Needle tube; 8. Squeezing bladder; 801. Bladder body; 802. Connecting pipe; 803. Steel ball; 804. Connecting rod; 805. Clamping sleeve; 806. Shielding membrane; 9. Feeding pipe; 10. Clamping frame; 11. Clamping ring pipe; 12. Suction head; 13. Manifold; 14. Ventilation pipe. Detailed Implementation
[0019] The present application will now be described in further detail with reference to the accompanying drawings. It should be noted that the following specific embodiments are only used to further illustrate the present application and should not be construed as limiting the scope of protection of the present application. Those skilled in the art can make some non-essential improvements and adjustments to the present application based on the above application content.
[0020] Example 1
[0021] like Figure 1-3 As shown, the freeze-dried powder injection anti-drip filling equipment of this embodiment includes a chassis 1, a conveyor belt 5 and a feeding box 2 on the chassis 1, guardrails 6 and photoelectric positioning sensors on both sides of the conveyor belt 5, a lifting frame 3 and a telescopic rod for driving the lifting frame 3 to rise and fall. The above structures are all direct references to the necessary components of existing filling equipment, and no specific limitations are made here.
[0022] The anti-drip filling equipment also includes several output components mounted on the lifting frame 3 and anti-leakage components corresponding to each output component;
[0023] The output component includes a feed tube 9, a squeezing bladder 8 and a needle tube connected sequentially from top to bottom. The squeezing bladder 8 includes a bladder body 801 and a steel ball 803 disposed in the bladder body 801.
[0024] The leak-proof assembly includes a clamping frame 10 and a clamping ring tube 11 sleeved on the outside of the output assembly, and a vertical rod for supporting the clamping frame 10 and the clamping ring tube 11. The clamping frame 10 is used to squeeze the bladder 801 from both sides, and the clamping ring tube 11 is used to surround and squeeze the bladder 801 to cooperate with the steel ball 803 to seal the squeeze bladder 8.
[0025] The output component also includes a material pump 4 mounted on the lifting frame 3. The material pump 4 is connected to the material supply box 2 via a hose, and the material conveying pipe 9 is mounted on the material pump 4 and connected to the material pump 4.
[0026] The anti-drip function of the filling equipment is implemented as follows: In the initial state, the squeezing bladder 8 is located at the highest point and is clamped by the clamping ring tube 11. In this state, the bladder 801 is squeezed and adhered to the steel ball 803, thereby achieving the effect of sealing the squeezing bladder 8.
[0027] During filling, the photoelectric positioning sensor detects that the vial has moved to below the syringe 7. The lifting frame 3 drives the output component to move down until the capsule 801 slides into the inside of the clamping frame 10. At this time, the bottom end of the syringe 7 extends into the vial to be filled. Then the feed pump 4 is turned on to draw the material in the feed box 2 into the feed pipe 9. The material then passes through the squeezing capsule 8 and the syringe 7 and is output.
[0028] After filling is completed, the lifting frame 3 drives the output component to move upward back to the initial position. During this process, the squeezing bladder 8 first slides out from the clamping frame 10. The squeezing bladder 8 returns to the normal state from the squeezed state and achieves the reverse suction state, drawing the material in the needle tube 7 into the squeezing bladder 8. Subsequently, the squeezing bladder 8 continues to move upward to the initial position, and the clamping ring tube 11, together with the steel ball 803, re-seals the squeezing bladder 8.
[0029] Subsequently, the conveyor belt 5 moves the next vial to below the syringe 7, and the above steps are repeated for continuous filling.
[0030] During the filling interval between the two vials, the material inside the syringe 7 is drawn back into the squeezing bladder 8, and the squeezing bladder 8 is blocked, which prevents the material in the delivery tube 9 from flowing downwards continuously. This avoids the problem of material leakage during the filling interval.
[0031] Preferably, both the inlet and outlet of the capsule 801 are provided with connecting pipes 802, and the steel ball 803 is connected to the connecting pipes 802 through a T-shaped connecting rod 804;
[0032] The combination of the connecting pipe 802, the connecting rod 804, and the steel ball 803 can establish a rigid connection between the feed tube 9 and the needle tube 7, preventing the needle tube 7 from shaking during the up and down movement and ensuring that the needle tube 7 can be accurately aligned with the vial.
[0033] Preferably, a clamping sleeve 805 is provided at the output port of the capsule 801, and the clamping sleeve 805 is made of rubber.
[0034] The feed tube 9 and needle tube 7 can be connected and fixed to the corresponding connecting tube 802 by snap-fit or threaded connection. For needle tube 7, which is too thin to be threaded, snap-fit is the only option. The clamping sleeve 805 can strengthen the clamping of needle tube 7.
[0035] Preferably, the connecting tube 802 that connects to the needle tube 7 is provided with a shielding membrane 806 with a central slit. During material conveying, the material can be squeezed by the shielding membrane 806 to achieve continuous conveying. After the squeezing bladder 8 is blocked, the shielding membrane 806 can delay the process of the material seeping down below the steel ball 803, prolong the time required for the material to leak out from the bottom of the needle tube 7, and ensure that the subsequent vials can be in place and the next filling can be started within this time.
[0036] Example 2
[0037] Based on Example 1, the freeze-dried powder injection anti-drip filling equipment of this example also includes a cleaning mechanism. The cleaning mechanism includes a manifold 13 on the chassis 1 and a suction head 12 corresponding to the needle tube 7. The suction head 12 is aligned with the needle tube 7 and connected to the manifold 13. The manifold 13 is provided with a ventilation pipe 14 for connecting an external fan.
[0038] When filling needs to be paused, the pause time is much longer than the interval time in the continuous filling process. In this case, the material in the squeezing bladder 8 located below the steel ball 803 may still leak down. At this time, the cleaning mechanism is turned on, and the suction head 12 is aligned with the bottom port of the needle tube 7. Once the material leaks out, it will immediately enter the manifold 13 and ventilation pipe 14 under the drive of the airflow for centralized transportation.
[0039] The embodiments described above are merely examples of several implementations of this utility model, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of this utility model patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these modifications and improvements all fall within the protection scope of this utility model.
Claims
1. A freeze-dried powder injection anti-drip filling device, comprising a chassis (1), a conveyor belt (5) and a feeding box (2) disposed on the chassis (1), guardrails (6) and photoelectric positioning sensors disposed on both sides of the conveyor belt (5), a lifting frame (3), and a telescopic rod for driving the lifting frame (3) to rise and fall, characterized in that: It also includes several output components installed on the lifting frame (3) and a leak-proof component corresponding to each output component; The output component includes a feed tube (9), a squeezing bladder (8) and a needle tube (7) connected sequentially from top to bottom. The squeezing bladder (8) includes a bladder body (801) and a steel ball (803) disposed in the bladder body (801). The leak-proof assembly includes a clamping frame (10) and a clamping ring tube (11) sleeved on the outside of the output assembly, and a vertical rod for supporting the clamping frame (10) and the clamping ring tube (11). The clamping frame (10) is used to squeeze the bladder (801) from both sides, and the clamping ring tube (11) is used to surround the bladder (801) to cooperate with the steel ball (803) to seal the bladder (8).
2. The anti-drip filling equipment for freeze-dried powder injections according to claim 1, characterized in that: The output component also includes a material pump (4) mounted on the lifting frame (3). The material pump (4) is connected to the feeding box (2) via a hose. The material conveying pipe (9) is mounted on the material pump (4) and connected to the material pump (4).
3. The anti-drip filling equipment for freeze-dried powder injections according to claim 1, characterized in that: The inlet and outlet of the capsule (801) are provided with connecting pipes (802), and the steel ball (803) is connected to the connecting pipes (802) through a T-shaped connecting rod (804).
4. The anti-drip filling equipment for freeze-dried powder injections according to claim 1, characterized in that: The output port of the capsule (801) is provided with a clamping sleeve (805).
5. The anti-drip filling equipment for freeze-dried powder injections according to claim 2, characterized in that: The connecting tube (802) that is connected to the needle tube (7) is provided with a shielding membrane (806) with a central slit.
6. The anti-drip filling equipment for freeze-dried powder injections according to claim 1, characterized in that: It also includes a cleaning mechanism, which includes a manifold (13) on the chassis (1) and a suction head (12) corresponding to the needle tube (7). The suction head (12) is aligned with the needle tube (7) and connected to the manifold (13). The manifold (13) is provided with a ventilation pipe (14) for connecting an external fan.