A raw material mixing device for producing oral solid tablets

Abstract

This utility model discloses a raw material mixing device for the production of oral solid tablets, relating to the field of oral solid tablet production technology. It includes: a carrying and driving mechanism for mounting a rotating mechanism and a sealing mechanism; a rotating mechanism for driving multiple sets of raw material receiving and mixing mechanisms to sequentially move to the mixing station; and multiple sets of raw material receiving and mixing mechanisms, any one of which can be detachably mounted on the rotating mechanism. After the raw material is mixed, this utility model allows for convenient emptying and cleaning of the receiving cylinder. Furthermore, removing any set of raw material receiving and mixing mechanisms does not affect the continued mixing process, thus improving overall mixing efficiency.

Description

Technical Field

[0001] This utility model relates to the field of oral solid tablet production technology, and in particular to a raw material mixing device for oral solid tablet production. Background Technology

[0002] Metoprolol tartrate tablets are a commonly used beta-blocker in clinical practice, mainly used for the treatment of cardiovascular diseases. Captopril tablets are a commonly used angiotensin-converting enzyme inhibitor in clinical practice, mainly used for the treatment of cardiovascular diseases such as hypertension and heart failure. Both of these oral solid tablets require the powdered raw materials to be mixed evenly before being made into tablets.

[0003] In the prior art, the raw material mixing devices used for the production of the above two types of oral solid tablets are mostly conventional. After the raw materials are mixed, it is not convenient to discharge the mixed raw materials. In addition, it is also very inconvenient to clean the mixing chamber. The cleaning process requires stopping the machine and waiting, which has a significant impact on the overall mixing efficiency.

[0004] Therefore, it is necessary to invent a raw material mixing device for the production of oral solid tablets to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a raw material mixing device for the production of oral solid tablets. After the raw material is mixed, it can be easily poured out, and the container used to hold the raw material can be easily cleaned. In addition, removing any set of raw material holding and mixing mechanisms will not affect the continued mixing of raw materials, thus improving the overall mixing efficiency. This solves the problems mentioned in the background art, such as the inconvenience of discharging the mixed raw material after mixing, the inconvenience of cleaning the mixing chamber, and the need to stop the machine for waiting during the cleaning process, which has a significant impact on the overall mixing efficiency.

[0006] According to one aspect of this disclosure, a technical solution is provided as follows: a mixing apparatus for raw materials in the production of oral solid tablets, comprising:

[0007] A load-bearing drive mechanism is used to mount the rotating mechanism and the sealing mechanism;

[0008] A rotating mechanism is used to drive multiple sets of raw material container mixing mechanisms to move sequentially to the mixing station;

[0009] Multiple sets of raw material receiving and mixing mechanisms are provided. Any set of raw material receiving and mixing mechanisms can be detachably mounted on a rotating mechanism. Each set of raw material receiving and mixing mechanisms includes a receiving cylinder for holding raw materials and located inside an adjacent clearance channel. A limiting part adapted to a limiting groove is fixedly provided on the top outer side of the receiving cylinder. A positioning part adapted to a positioning groove is fixedly provided on the outer side of the limiting part. Two handles distributed vertically are fixedly provided on the side of the receiving cylinder. A rotating shaft is rotatably nested in the receiving cylinder via a bearing. The bottom end of the rotating shaft extends to the bottom of the receiving cylinder and is fixedly connected to an upper turntable. A driven lever is fixedly provided on the outer side of the bottom of the upper turntable.

[0010] A positioning mechanism, wherein the positioning mechanism is used for positioning when the rotating mechanism drives the active pharmaceutical ingredient containing and mixing mechanism to move; and

[0011] A sealing mechanism for sealing the top opening of an adjacent raw material receiving and mixing mechanism.

[0012] According to at least one embodiment of the present disclosure, an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets includes a support drive mechanism comprising a support base, wherein upper clearance grooves are provided on the top of all four sides of the support base, and lower clearance grooves are provided on the bottom of all four sides of the support base.

[0013] According to at least one embodiment of the present disclosure, an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets has a column fixedly disposed at the top center of the support base.

[0014] According to at least one embodiment of the present disclosure, a raw material mixing apparatus for the production of oral solid tablets includes a motor fixedly installed on the rear side inside the support base, the output shaft of the motor extending to the top of the support base and fixedly connected to a lower turntable, and an active lever fixedly installed on the outer side of the top of the lower turntable.

[0015] According to at least one embodiment of the present disclosure, an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets includes a rotating mechanism comprising a rotating frame rotatably sleeved on the outside of a column via bearings, wherein a plurality of clearance channels are uniformly provided on the outside of the rotating frame.

[0016] According to at least one embodiment of the present disclosure, a raw material mixing apparatus for the production of oral solid tablets has a plurality of limiting grooves uniformly provided on the top of the rotating frame, and any one of the limiting grooves is uniformly connected to an adjacent clearance channel, and a positioning groove is provided on the inner side of the limiting groove.

[0017] According to at least one embodiment of the present disclosure, an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets includes a positioning mechanism comprising a fixed plate fixedly sleeved on the top of the outer side of a column, wherein a plurality of upper positioning magnets are uniformly and fixedly nested at the bottom of the fixed plate.

[0018] According to at least one embodiment of the present disclosure, in the raw material mixing apparatus for the production of oral solid tablets, the positioning mechanism further includes a plurality of lower positioning magnets uniformly fixed on the top of the rotating frame, wherein any one of the lower positioning magnets is magnetically attracted to the adjacent upper positioning magnet directly below it.

[0019] According to at least one embodiment of the present disclosure, an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets includes a sealing mechanism comprising a fixed frame fixedly disposed on the top rear side of a support base, wherein an electric push rod is fixedly disposed on the top of the fixed frame.

[0020] According to at least one embodiment of the present disclosure, in an apparatus for mixing active pharmaceutical ingredients for the production of oral solid tablets, the output of the electric push rod extends to the bottom of the fixed frame and is fixedly connected to a sealing cover, wherein a sealing ring is adhesively provided at the bottom of the sealing cover.

[0021] The technical effects and advantages of this utility model are as follows:

[0022] This invention detachably mounts multiple raw material receiving and mixing mechanisms onto a rotating mechanism. The rotating mechanism drives these mechanisms sequentially through the mixing station. After the raw materials are mixed and the mechanisms move from the mixing station to the loading / unloading station on the front of the device, the handle can be gripped to move the receiving cylinder upwards within the clearance channel until the limiting part and positioning part move out of the limiting groove and positioning groove. Then, the handle moves the receiving cylinder out of the clearance channel opening, allowing the mixed raw materials inside to be poured out. The inner cavity of the receiving cylinder can then be directly cleaned. Compared to similar devices in the prior art, this invention allows for easier pouring out of the mixed raw materials and easier cleaning of the receiving cylinder. Furthermore, removing any set of raw material receiving and mixing mechanisms does not affect the continued mixing process, thus improving overall mixing efficiency. Attached Figure Description

[0023] The accompanying drawings illustrate exemplary embodiments of the present disclosure and, together with the description thereof, serve to explain the principles of the present disclosure. These drawings are included to provide a further understanding of the present disclosure and are incorporated in and constitute a part of this specification.

[0024] Figure 1 This is a schematic diagram of the overall structure of a drug substance mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0025] Figure 2 This is a partial structural diagram of the support drive mechanism and positioning mechanism of an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0026] Figure 3 This is a partial structural diagram of the rotating mechanism and positioning mechanism of an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0027] Figure 4 This is a schematic diagram of the raw material containing and mixing mechanism of a raw material mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0028] Figure 5 This is a schematic diagram of the sealing mechanism of a drug substance mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0029] The specific labels in the attached figures are as follows:

[0030] 1. Bearing drive mechanism; 11. Bearing base; 12. Upper clearance groove; 13. Lower clearance groove; 14. Column; 15. Motor; 16. Lower turntable; 17. Active lever;

[0031] 2. Rotating mechanism; 21. Rotating frame; 22. Clearance passage; 23. Limiting groove; 24. Positioning groove;

[0032] 3. Raw material receiving and mixing mechanism; 31. Receiving cylinder; 32. Limiting part; 33. Positioning part; 34. Handle; 35. Rotating shaft; 36. Upper turntable; 37. Driven lever;

[0033] 4. Positioning mechanism; 41. Fixing plate; 42. Upper positioning magnet; 43. Lower positioning magnet;

[0034] 5. Sealing mechanism; 51. Fixing frame; 52. Electric push rod; 53. Sealing cover; 54. Sealing ring. Detailed Implementation

[0035] For descriptive purposes, this disclosure may use spatial relative terms such as “below,” “under,” “below,” “down,” “above,” “above,” “higher,” and “side (e.g., in a “sidewall”)” to describe the relationship between one component and another component as shown in the accompanying drawings. In addition to the orientations depicted in the drawings, the spatial relative terms are also intended to encompass different orientations of the device during use, operation, and / or manufacture. For example, if the device in the drawings is flipped, a component described as “below” or “under” other components or features would subsequently be positioned “above” said other components or features. Thus, the exemplary term “below” can encompass both “above” and “below” orientations. Furthermore, the device may be otherwise positioned (e.g., rotated 90 degrees or in other orientations), thus interpreting the spatial relative descriptive terms used herein accordingly.

[0036] Figure 1 This is a schematic diagram of the overall structure of a drug substance mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0037] Figure 2 This is a partial structural diagram of the carrying drive mechanism 1 and the positioning mechanism 4 of an oral solid tablet manufacturing raw material mixing apparatus according to one embodiment of the present disclosure.

[0038] Figure 3 This is a partial structural diagram of the rotating mechanism 2 and the positioning mechanism 4 of an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0039] Figure 4 This is a schematic diagram of the raw material containing and mixing mechanism 3 of an oral solid tablet manufacturing apparatus according to one embodiment of the present disclosure.

[0040] Figure 5 This is a schematic diagram of the sealing mechanism 5 of an active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets according to one embodiment of the present disclosure.

[0041] like Figures 1-5 As shown, the active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets disclosed herein may include components such as a carrying drive mechanism 1, a rotating mechanism 2, an active pharmaceutical ingredient containing and mixing mechanism 3, a positioning mechanism 4, and a sealing mechanism 5.

[0042] like Figure 2 As shown in this disclosure, the load-bearing drive mechanism 1 includes a load-bearing base 11. The top of the load-bearing base 11 is provided with an upper clearance groove 12, and the bottom of the load-bearing base 11 is provided with a lower clearance groove 13. A column 14 is fixedly installed at the center of the top of the load-bearing base 11. A motor 15 is fixedly installed inside the rear side of the load-bearing base 11. The output shaft of the motor 15 extends to the top of the load-bearing base 11 and is fixedly connected to a lower turntable 16. An active lever 17 is fixedly installed on the outer side of the top of the lower turntable 16.

[0043] Therefore, the upper clearance groove 12 and the lower clearance groove 13 are designed so that when the raw material containing and mixing mechanism 3 is removed from the rotating mechanism 2, the supporting base 11 can make clearance, thereby reducing the difficulty of disassembling and assembling the raw material containing and mixing mechanism 3.

[0044] like Figure 3 As shown, in a preferred embodiment, the rotating mechanism 2 includes a rotating frame 21 that is rotatably sleeved on the outside of the column 14 via a bearing. Multiple clearance channels 22 are evenly provided on the outside of the rotating frame 21, and multiple limiting grooves 23 are evenly provided on the top of the rotating frame 21. Any one of the limiting grooves 23 is evenly connected to the clearance channel 22, and a positioning groove 24 is provided on the inner side of the limiting groove 23.

[0045] Therefore, in order to facilitate the rotation of the rotating frame 21, the rotating frame 21 drives multiple sets of raw material receiving and mixing mechanisms 3 to pass through the mixing station in sequence. The limiting groove 23 can limit the raw material receiving and mixing mechanism 3 to prevent it from falling off during the rotation of the rotating frame 21. The positioning groove 24 can position the raw material receiving and mixing mechanism 3, thereby ensuring that the raw material receiving and mixing mechanism 3 is accurately mounted on the rotating frame 21.

[0046] like Figure 4 As shown in this disclosure, any set of raw material containing and mixing mechanisms 3 can be detachably mounted on the rotating mechanism 2. Any set of raw material containing and mixing mechanisms 3 includes a containing cylinder 31 for holding raw materials and located inside the adjacent clearance channel 22. A limiting part 32 adapted to the limiting groove 23 is fixedly mounted on the top of the outer side of the containing cylinder 31. A positioning part 33 adapted to the positioning groove 24 is fixedly mounted on the outer side of the limiting part 32. Two handles 34 distributed vertically are fixedly mounted on the side of the containing cylinder 31. A rotating shaft 35 is rotatably nested in the containing cylinder 31 through a bearing. The bottom end of the rotating shaft 35 extends to the bottom of the containing cylinder 31 and is fixedly connected to an upper turntable 36. A driven lever 37 is fixedly mounted on the outer side of the bottom of the upper turntable 36.

[0047] Therefore, after the raw material containing and mixing mechanism 3 arrives at the mixing station, the motor 15 drives the active push block 17 to rotate through the lower turntable 16. The active push block 17 then drives the upper turntable 36 located directly above the lower turntable 16 to rotate through the adjacent driven push block 37. When the upper turntable 36 rotates, it drives the rotating shaft 35 to rotate continuously inside the containing cylinder 31, thereby mixing the powdered raw material inside the containing cylinder 31. After the raw material is mixed, the handle 34 can be held and the containing cylinder 31 can be moved upward inside the clearance channel 22 until the limiting part 32 moves out from the inside of the limiting groove 23 and the positioning part 33 moves out from the inside of the positioning groove 24. Then, the handle 34 drives the containing cylinder 31 to move out from the opening of the clearance channel 22. Then, the mixed raw material inside the containing cylinder 31 can be poured out, and then the inner cavity of the containing cylinder 31 can be directly cleaned.

[0048] like Figure 2 and Figure 3 As shown, in a preferred embodiment, the positioning mechanism 4 includes a fixed plate 41 fixedly sleeved on the top of the outer side of the column 14. Multiple upper positioning magnets 42 are uniformly fixedly nested at the bottom of the fixed plate 41. The positioning mechanism 4 also includes multiple lower positioning magnets 43 uniformly fixedly sleeved on the top of the rotating frame 21. Any one of the lower positioning magnets 43 is magnetically attracted to the lower side of the adjacent upper positioning magnet 42.

[0049] Therefore, when the rotating frame 21 drives multiple sets of raw material receiving and mixing mechanisms 3 to pass through the mixing station in sequence, multiple lower positioning magnets 43 pass under multiple upper positioning magnets 42 in sequence, thus repeating the magnetic attraction and demagnetization operation. At the same time, when any set of raw material receiving and mixing mechanisms 3 moves to the mixing station, multiple lower positioning magnets 43 are magnetically attracted to the underside of multiple upper positioning magnets 42 respectively, thereby increasing the resistance when the rotating frame 21 rotates, making it easier for the staff to know that the raw material receiving and mixing mechanism 3 has arrived at the mixing station.

[0050] like Figure 5 As shown in this disclosure, the sealing mechanism 5 includes a fixed frame 51 fixedly disposed on the top rear side of the support base 11. An electric push rod 52 is fixedly disposed on the top of the fixed frame 51. After the output of the electric push rod 52, it extends to the bottom of the fixed frame 51 and is fixedly connected to a sealing cover 53. A sealing ring 54 is bonded to the bottom of the sealing cover 53.

[0051] Therefore, after the raw material containing and mixing mechanism 3 moves to the mixing station below the sealing cover 53 under the drive of the rotating mechanism 2, the electric push rod 52 drives the sealing cover 53 to move continuously downward until the sealing ring 54 is attached to the top of the adjacent containing cylinder 31 and seals it, thereby preventing some raw material from entering the indoor air through the opening of the containing cylinder 31 due to stirring during the mixing process of the powdered raw material.

[0052] It should also be noted that any content not described in detail in this specification is prior art known to those skilled in the art.

[0053] Those skilled in the art should understand that the above embodiments are merely for illustrating the present disclosure and are not intended to limit the scope of the disclosure. Those skilled in the art can make other changes or modifications based on the above disclosure, and these changes or modifications still fall within the scope of the present disclosure.

Claims

1. A raw material mixing device for oral solid tablet production, characterized by, include: A load-bearing drive mechanism is used to mount the rotating mechanism and the sealing mechanism; A rotating mechanism is used to drive multiple sets of raw material container mixing mechanisms to move sequentially to the mixing station; Multiple sets of raw material receiving and mixing mechanisms are provided. Any set of raw material receiving and mixing mechanisms can be detachably mounted on a rotating mechanism. Each set of raw material receiving and mixing mechanisms includes a receiving cylinder for holding raw materials and located inside an adjacent clearance channel. A limiting part adapted to a limiting groove is fixedly provided on the top outer side of the receiving cylinder. A positioning part adapted to a positioning groove is fixedly provided on the outer side of the limiting part. Two handles distributed vertically are fixedly provided on the side of the receiving cylinder. A rotating shaft is rotatably nested in the receiving cylinder via a bearing. The bottom end of the rotating shaft extends to the bottom of the receiving cylinder and is fixedly connected to an upper turntable. A driven lever is fixedly provided on the outer side of the bottom of the upper turntable. A positioning mechanism, wherein the positioning mechanism is used for positioning when the rotating mechanism drives the active pharmaceutical ingredient containing and mixing mechanism to move; and A sealing mechanism for sealing the top opening of an adjacent raw material receiving and mixing mechanism.

2. The raw material mixing device for oral solid tablet production according to claim 1, characterized in that: The load-bearing drive mechanism includes a load-bearing base, with upper clearance grooves on the top of all four sides of the load-bearing base and lower clearance grooves on the bottom of all four sides of the load-bearing base.

3. The raw material mixing device for oral solid tablet production according to claim 2, characterized in that: A column is fixedly installed at the center of the top of the support base.

4. The raw material mixing device for producing an oral solid tablet according to claim 3, characterized by: A motor is fixedly installed inside the rear side of the support base. The output shaft of the motor extends to the top of the support base and is fixedly connected to a lower turntable. An active toggle block is fixedly installed on the outer side of the top of the lower turntable.

5. The raw material mixing device for producing an oral solid tablet according to claim 4, characterized by: The rotating mechanism includes a rotating frame that is rotatably sleeved on the outside of the column via a bearing, and multiple clearance channels are evenly provided on the outside of the rotating frame.

6. The raw material mixing device for producing an oral solid tablet according to claim 5, characterized by: The top of the rotating frame is evenly provided with multiple limiting grooves, and any one of the limiting grooves is evenly connected to the avoidance channel. A positioning groove is provided on the inner side of the limiting groove.

7. The active pharmaceutical ingredient mixing apparatus for the production of oral solid tablets according to claim 6, characterized in that: The positioning mechanism includes a fixed plate that is fixedly sleeved on the top of the outer side of the column, and multiple upper positioning magnets are uniformly fixedly nested at the bottom of the fixed plate.

8. The raw material mixing device for producing an oral solid tablet according to claim 7, characterized by: The positioning mechanism also includes multiple lower positioning magnets that are uniformly fixed on the top of the rotating frame, and each of the lower positioning magnets is magnetically attracted to the area directly below the adjacent upper positioning magnet.

9. The raw material mixing device for producing an oral solid tablet according to claim 8, characterized by: The sealing mechanism includes a fixed frame fixedly installed on the top rear side of the support base, and an electric push rod is fixedly installed on the top of the fixed frame.

10. The raw material mixing device for producing an oral solid tablet according to claim 9, characterized by: The output of the electric push rod extends to the bottom of the fixed frame and is fixedly connected to a sealing cover, and a sealing ring is bonded to the bottom of the sealing cover.

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