A blow-fill-seal device with adjustable filling volume

Abstract

This utility model discloses a blow-fill-seal device with adjustable filling volume, relating to the field of pharmaceutical equipment technology. It includes: a visual liquid level detection unit for real-time capture of the liquid level image of the finished bottle in the product chain after molding and filling; the visual liquid level detection unit includes a light source and a liquid level vision camera; a filling system including an air source, a storage tank, and a filling needle assembly; the storage tank and the filling needle assembly are connected by a sterile pipeline; the air source is used to pressurize the liquid medicine from the storage tank into the filling needle assembly; the filling needle assembly is connected to a valve; and a control system connected to the liquid level vision camera and valve signals, the control system being used to adjust the valve opening duration. The above-mentioned blow-fill-seal device with adjustable filling volume monitors the filling liquid level of each bottle in real time through the visual liquid level detection unit, dynamically adjusting the filling volume of the plastic bottle through the valve via the filling needle assembly.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical equipment technology, and in particular to a blow-fill-seal device with adjustable filling volume. Background Technology

[0002] The blow-fill-seal integrated machine is a pharmaceutical equipment mainly used for the aseptic filling production of plastic ampoules. It completes the production of plastic ampoules, filling of medicine, and sealing of products with a single machine.

[0003] Traditional blow-fill-seal equipment relies on manual sampling to observe the liquid level and then adjusting the filling volume for each bottle, which has the following drawbacks:

[0004] Inefficient: Manually observing the liquid level and then returning to adjust the filling time, followed by observing the liquid level and making adjustments again, is time-consuming and labor-intensive, especially when filling multiple bottles simultaneously, the efficiency will be even lower.

[0005] Waste of pharmaceutical solution: The commissioning process requires continuous production until the liquid level is qualified, resulting in significant loss of high-value pharmaceutical solutions and waste of pharmaceutical solutions.

[0006] Reliance on experience: The observation and adjustment process is highly dependent on the experience level of the staff. When changing the mold or the viscosity of the liquid, it is necessary to readjust the process, which requires high skill level from the staff.

[0007] Therefore, the existing technology still has shortcomings and deficiencies. How to provide a blow-fill-seal device with adjustable filling volume is a technical problem that urgently needs to be solved by those skilled in the art. Utility Model Content

[0008] The purpose of this invention is to provide a blow-fill-seal device with adjustable filling volume, which solves the technical problem of traditional blow-fill-seal devices that rely on manual sampling and observation of liquid level to adjust the filling volume of each bottle, resulting in many defects.

[0009] To achieve the above objectives, this utility model provides a blow-fill-seal device with adjustable filling volume, comprising:

[0010] A visual liquid level detection unit is used to capture liquid level images of finished bottles in the product chain after molding and filling in real time. The visual liquid level detection unit includes a light source and a liquid level vision camera.

[0011] A filling system includes an air source, a liquid storage tank, and a filling needle assembly. The liquid storage tank and the filling needle assembly are connected by a sterile pipeline. The air source is used to pressurize the liquid medicine from the liquid storage tank into the filling needle assembly. The filling needle assembly is connected to a valve.

[0012] The control system is connected to the liquid level vision camera and the valve signal, and is used to adjust the opening duration of the valve.

[0013] Preferably, the filling system further includes a filling lifting electric cylinder arranged in a vertical direction, which is used to drive the filling needle assembly to move vertically up and down.

[0014] Preferably, an openable molding die is provided below the filling needle assembly. The molding die is used to blow mold a continuous tube preform into a preset bottle shape. The molding die includes an upper die and a lower die.

[0015] Preferably, a bracket is fixedly provided below the molding die, and the light source and liquid level vision camera are mounted on the bracket.

[0016] Preferably, the bracket is fixedly equipped with a horizontally arranged telescopic electric cylinder, and the light source is fixedly installed at the telescopic end of the telescopic electric cylinder.

[0017] Preferably, a clamping component for clamping the product chain during the mold opening stage is fixedly provided below the molding die.

[0018] Preferably, the clamping assembly includes:

[0019] The mounting platform is fixedly located below the molding mold;

[0020] The mounting plate has an L-shaped structure and is movably mounted on the side of the mounting platform;

[0021] An electric clamp, mounted on top of the mounting plate, includes two grippers that can move closer to and further away from each other.

[0022] Preferably, the mounting plate is movably mounted on the mounting platform via a lifting mechanism, the lifting mechanism comprising:

[0023] Two mounting bases are fixedly mounted on the side of the mounting platform;

[0024] A lead screw is rotatably connected between the two mounting bases;

[0025] The screw hole block is threadedly connected to the lead screw;

[0026] A slide rail is fixedly mounted vertically on the side of the mounting platform. A slider is fixedly mounted on the side of the mounting plate. The slider has a groove and is slidably connected to the slide rail through the groove.

[0027] The screw hole block is fixedly connected to the mounting plate.

[0028] Preferably, it also includes a conveying device located below the molding die, the conveying device being used to convey the molded and filled plastic bottles.

[0029] Preferably, the valve is a proportional solenoid valve.

[0030] Preferably, it also includes a punching system, which includes an upper punching die, a lower punching die, and a punching lifting electric cylinder.

[0031] Compared to the aforementioned background technology, the blow-fill-seal equipment with adjustable filling volume provided by this utility model acquires liquid level images of finished bottles in the product chain through a liquid level vision camera. The control system compares the liquid level images of finished bottles in the product chain with the standard liquid level. By controlling the opening time of the valve, the filling volume of the filling needle assembly into the plastic bottle through the valve is dynamically adjusted in real time until the filling volume meets the requirements. This can effectively save the time for adjusting the filling of medicine, reduce the waste of medicine during debugging, lower the requirements for debugging personnel, and improve production efficiency. Attached Figure Description

[0032] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0033] Figure 1 A schematic diagram of the structure of the blow-fill-seal device with adjustable filling volume provided in an embodiment of this utility model;

[0034] Figure 2 This is a schematic diagram of the product chain provided in an embodiment of the present utility model.

[0035] Figures 1 to 2 Chinese figure reference numerals: 1. Extrusion die head; 2. Continuous tube preform; 3. Support; 4. Product chain; 5. Light source; 6. Liquid level vision camera; 7. Conveying device; 8. Molding mold; 9. Filling needle assembly; 10. Telescopic electric cylinder; 11. Mounting platform; 12. Mounting plate; 13. Electric clamp. Detailed Implementation

[0036] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0037] To enable those skilled in the art to better understand the present invention, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0038] This invention provides a blow-fill-seal device with adjustable filling volume. The device monitors the filling level of each bottle in real time through a visual liquid level detection unit, controls the opening duration of the valve through the control system, and dynamically adjusts the filling volume of the filling needle group 9 through the valve to fill the plastic bottle.

[0039] Please refer to this as well. Figures 1 to 2 The blow-fill-seal device with adjustable filling volume provided by this utility model includes:

[0040] The visual liquid level detection unit is used to capture the liquid level image of the finished bottle in the product chain 4 after molding and filling in real time. The visual liquid level detection unit includes a light source 5 and a liquid level vision camera 6.

[0041] The filling system includes an air source, a liquid storage tank, and a filling needle assembly 9. The liquid storage tank and the filling needle assembly 9 are connected by a sterile pipeline. The air source is used to pressurize the liquid medicine from the liquid storage tank into the filling needle assembly 9. The filling needle assembly 9 is connected to a valve.

[0042] The control system is connected to the liquid level vision camera 6 and the valve signal. The control system is used to adjust the valve opening time.

[0043] The filling system fills the liquid medicine into molded plastic bottles. A high-brightness light source 5 illuminates the bottle from the side, creating a clear boundary between light and dark areas on the liquid surface. This allows the liquid level vision camera 6 to capture a sharp edge, acquiring images of the liquid level in the finished bottles in product chain 4. The control system compares these images with standard liquid levels. If the liquid level in the finished bottle is lower than the standard level, the control system extends the valve opening time in the filling system; if the liquid level is the same as the standard level, the control system keeps the valve opening time constant; if the liquid level is higher than the standard level, the control system shortens the valve opening time. By controlling the valve opening time, the control system dynamically adjusts the filling volume of the filling needle assembly 9 into the plastic bottle. Real-time adjustments are made when the filling volume does not meet the standard level until the required volume is achieved.

[0044] This setup effectively saves time on filling and adjusting the medicine, reduces waste of medicine during debugging, lowers the requirements for debugging personnel, and improves production efficiency.

[0045] Specifically, compressed air is generated by an air compressor. After being stabilized by a triple unit, the compressed air is purified by a sterile filter. The purified compressed air enters the storage tank, and the air source pressure propels the liquid medicine through the sterile pipeline into the filling needle assembly 9. A proportional solenoid valve can be used as the valve.

[0046] A pneumatic piston is installed inside the storage tank. Air pressure pushes the pneumatic piston, which in turn pushes a plunger in the drug chamber of the storage tank, thus forcing the drug into the filling needle assembly 9. This design prevents the drug from directly contacting the compressed air, further ensuring aseptic performance. Additionally, the blow-fill-seal equipment with adjustable filling volume includes an extrusion system for extruding the continuous tube preform 2. The extrusion system includes an extrusion motor, an extrusion screw, and an extrusion die 1. The extrusion motor is driven by the extrusion screw, and the extrusion screw is connected to the extrusion die 1.

[0047] During use, granules are continuously supplied to the extrusion screw. The granules are heated and melted inside the extrusion screw. The extrusion motor drives the extrusion screw to rotate, and the melted granules are extruded through the extrusion die 1 to form tube blanks of the corresponding wall thickness and shape.

[0048] In some embodiments, a closable molding die 8 is provided below the filling needle assembly 9. The molding die 8 is used to blow mold the continuous tube preform 2 into a preset bottle shape. The molding die 8 includes an upper die and a lower die.

[0049] A continuous tube preform 2 is extruded through an extrusion die 1, and then blow-molded into a preset bottle shape through a forming die 8. Specifically, when the upper and lower molds in the forming die 8 are closed, a sealed cavity is formed, and clean compressed air is injected into the cavity through the air blowing channel built into the upper or lower mold to blow-mold the tube preform.

[0050] In some embodiments, the filling system further includes a vertically oriented electric cylinder for driving the filling needle assembly 9 to move vertically. During filling, the electric cylinder drives the filling needle assembly 9 to move, and the filling needle assembly 9 is precisely inserted into the molded plastic bottle. After the valve is opened, the liquid medicine is injected.

[0051] In some embodiments, please refer to Figure 1 A bracket 3 is fixedly installed below the molding mold 8, and the light source 5 and the liquid level vision camera 6 are installed on the bracket 3.

[0052] The light source 5 and the liquid level vision camera 6 are located on the same side of the product chain 4. The light source 5 illuminates the bottle from the side, so that the liquid surface inside the plastic bottle forms a light-dark boundary line. Then, the liquid level image of the finished bottle in the product chain 4 is acquired by the liquid level vision camera 6.

[0053] In some embodiments, please refer to Figure 1 The bracket 3 is fixedly equipped with a horizontally arranged telescopic electric cylinder 10, and the light source 5 is fixedly installed at the telescopic end of the telescopic electric cylinder 10.

[0054] By setting up the telescopic electric cylinder 10, the distance between the light source 5 and the product chain 4 can be adjusted, making it easier for the liquid level vision camera 6 to capture clear images of the liquid level of the finished product bottles in the product chain 4.

[0055] In some embodiments, please refer to Figure 1 A clamping assembly for holding the product chain 4 during the mold opening stage is fixedly provided below the molding die 8. When the upper and lower molds in the molding die 8 open, the clamping assembly clamps the product chain 4 to fix it and prevent displacement, which is beneficial for the liquid level vision camera 6 to collect liquid level images of the finished bottles in the product chain 4. When the upper and lower molds close, the clamping assembly releases the product chain 4.

[0056] In some embodiments, please refer to Figure 1 The clamping components include:

[0057] Mounting platform 11 is fixedly located below molding mold 8;

[0058] Mounting plate 12, having an L-shaped structure, is movably mounted on the side of mounting platform 11;

[0059] The electric clamp 13 is mounted on the top of the mounting plate 12 and includes two grippers that can move closer to and further away from each other.

[0060] The mounting plate 12 can move vertically along the side of the mounting platform 11. As the mounting plate 12 moves, the position and height of the electric clamp 13 on the mounting plate 12 can be adjusted, making it convenient to clamp different areas of the product chain 4 according to actual needs.

[0061] In some embodiments, please refer to Figure 1 The mounting plate 12 is movably mounted on the mounting platform 11 via a lifting mechanism, which includes:

[0062] Two mounting bases are fixedly installed on the side of the mounting platform 11;

[0063] The lead screw is rotatably connected between two mounting bases;

[0064] The screw hole block is connected to the lead screw thread;

[0065] A slide rail is fixedly mounted vertically on the side of the mounting platform 11. A slider is fixedly mounted on the side of the mounting plate 12. The slider has a groove and is slidably connected to the slide rail through the groove.

[0066] The screw hole block is fixedly connected to the mounting plate 12.

[0067] Specifically, the screw hole block and the slider are fixedly connected to the vertical section of the mounting plate 12, while the electric clamp 13 is installed on the horizontal section of the mounting plate 12. The screw hole block is driven to slide along the screw by the drive motor, and the slider slides along the slide rail through the slide groove, so that the mounting plate 12 moves in the vertical direction, thereby changing the position and height of the electric clamp 13 on the mounting plate 12.

[0068] By setting sliders and slide rails, the sliding of the screw hole block along the lead screw can be limited and guided, ensuring structural stability and motion accuracy.

[0069] In some embodiments, please refer to Figure 1 The blow-fill-seal equipment with adjustable filling volume provided by this utility model also includes a conveying device 7 located below the molding mold 8. The conveying device 7 is used to convey the molded and filled plastic bottles. The molded and filled plastic bottles are conveyed by the conveying device 7, which can be a conveyor belt or the like.

[0070] Optionally, the blow-fill-seal equipment with adjustable filling volume provided by this utility model also includes a punching system, which includes an upper punching die, a lower punching die, and a punching lifting electric cylinder.

[0071] The upper punching die is equipped with a punch with a cutting edge that matches the contour of the plastic bottle, and the lower punching die is equipped with a base with a groove. The punching lifting electric cylinder is set in the vertical direction, and the telescopic end of the punching lifting electric cylinder is connected to the upper punching die.

[0072] After molding and filling, the plastic bottles are conveyed to the punching system via the conveying device 7. The punching lifting electric cylinder drives the upper punching die to move downward in the vertical direction. The upper punching die and the lower punching die close together. Through the cooperation of the cutting edge and the groove, the finished bottle is precisely separated from the tube preform chain.

[0073] Optionally, the punching system also includes vertically arranged guide columns. The upper punching die is slidably connected to the guide columns. When the punching lifting electric cylinder drives the upper punching die to move, the guide columns guide the movement of the upper punching die to ensure that the upper punching die moves in the vertical direction and avoids deviation, thereby ensuring punching accuracy and preventing misalignment of the tube blank chain, ensuring the stability of continuous production.

[0074] Optionally, the lower die is equipped with a vacuum adsorption hole. During the die-cutting process when the upper and lower dies are closed, the finished bottle is adsorbed and fixed through the vacuum adsorption hole to prevent the bottle from shifting and ensure the cutting accuracy.

[0075] In some embodiments, the punching system further includes a detection unit for monitoring the position of the finished bottle. Monitoring the position of the finished bottle by the detection unit ensures precise punching of the tube preform chain by the upper and lower punching dies, preventing incomplete or missed cuts. Specifically, the detection unit can employ a photoelectric sensor to detect the position of the finished bottle in real time.

[0076] In some embodiments, the punching system further includes a waste processing unit, which includes a waste traction roller and a collection box.

[0077] The upper and lower punching dies close together to precisely separate the finished bottle from the tube preform chain through the cooperation of the cutting edge and the groove. At the same time, the waste traction roller continuously pulls the waste material after punching and separation to move along the length of the equipment. Finally, the plastic waste after punching is collected in the collection box.

[0078] By setting up a waste processing unit, waste is continuously discharged from the edge, avoiding the accumulation of waste that interrupts the production process and ensuring the stability and continuity of the production process.

[0079] It should be noted that in this specification, relational terms such as first and second are used only to distinguish one entity from several other entities, and do not necessarily require or imply any such actual relationship or order between these entities.

[0080] This article uses specific examples to illustrate the principles and implementation methods of this utility model. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of this utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made to this utility model without departing from the principles of this utility model, and these improvements and modifications also fall within the protection scope of this utility model.

Claims

1. A blow-fill-seal apparatus for filling a variable volume, characterized in that, include: A visual liquid level detection unit is used to capture the liquid level image of the finished bottle in the product chain (4) after molding and filling in real time. The visual liquid level detection unit includes a light source (5) and a liquid level vision camera (6). The filling system includes an air source, a liquid storage tank and a filling needle assembly (9), wherein the liquid storage tank and the filling needle assembly (9) are connected by a sterile pipeline, the air source is used to press the liquid medicine from the liquid storage tank into the filling needle assembly (9), and the filling needle assembly (9) is connected to a valve; The control system is connected to the liquid level vision camera (6) and the valve signal, and the control system is used to adjust the opening duration of the valve.

2. The fill-to-content adjustable blow-fill-seal apparatus of claim 1, wherein, The filling needle assembly (9) is provided with an openable molding die (8) below it. The molding die (8) is used to blow mold the continuous tube preform (2) into a preset bottle shape. The molding die (8) includes an upper die and a lower die.

3. The fill-to-content adjustable blow-fill-seal apparatus of claim 2, wherein, A bracket (3) is fixedly provided below the molding mold (8), and the light source (5) and the liquid level vision camera (6) are mounted on the bracket (3).

4. The blow-fill-seal equipment with adjustable filling volume according to claim 3, characterized in that, The bracket (3) is fixedly equipped with a horizontally arranged telescopic electric cylinder (10), and the light source (5) is fixedly installed at the telescopic end of the telescopic electric cylinder (10).

5. The fill-to-content adjustable blow-fill-seal apparatus of claim 2, wherein, The molding die (8) is fixedly provided with a clamping component for clamping the product chain (4) during the mold opening stage.

6. The fill-level-adjustable blow-fill-seal apparatus of claim 5, wherein, The clamping assembly includes: The mounting platform (11) is fixedly located below the molding die (8); The mounting plate (12) has an L-shaped structure and is movably disposed on the side of the mounting platform (11); An electric clamp (13) is mounted on the top of the mounting plate (12) and includes two grippers that can move closer to and further away from each other.

7. A fill-to-volume adjustable blow-fill-seal apparatus according to claim 6, wherein, The mounting plate (12) is movably mounted on the mounting platform (11) via a lifting mechanism, the lifting mechanism comprising: Two mounting bases are fixedly disposed on the side of the mounting platform (11); A lead screw is rotatably connected between the two mounting bases; The screw hole block is threadedly connected to the lead screw; A slide rail is fixedly mounted on the side of the mounting platform (11) in a vertical direction. A slider is fixedly mounted on the side of the mounting plate (12). The slider is provided with a sliding groove and is slidably connected to the slide rail through the sliding groove. The screw hole block is fixedly connected to the mounting plate (12).

8. The fill-to-content adjustable blow-fill-seal apparatus of claim 2, wherein, It also includes a conveying device (7) located below the molding die (8), the conveying device (7) being used to convey the molded and filled plastic bottles.

9. The fill-to-content adjustable blow-fill-seal apparatus of claim 1, wherein, The valve is a proportional solenoid valve.

10. The fill-to-content adjustable blow-fill-seal apparatus of claim 1, wherein, It also includes a punching system, which includes an upper punching die, a lower punching die, and a punching lifting electric cylinder.

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