Sampling system

By designing an automated sampling system, the problems of cumbersome sampling operations and pollution risks in water systems during pharmaceutical processes were solved, achieving an efficient and safe sampling process.

CN224456284UActive Publication Date: 2026-07-03CHUTIAN HUATONG PHARM EQUIP CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
CHUTIAN HUATONG PHARM EQUIP CO LTD
Filing Date
2025-07-11
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

In existing pharmaceutical processes, water system sampling requires staff to go to dispersed locations to collect samples, which is cumbersome, affects production efficiency, and is prone to polluting the clean environment.

Method used

Design a sampling system including a movable sealing plate, a movable carrier, a sampling device, and a cargo tray. The system replaces manual operation with an automated sampling device and combines a drive mechanism, an identification device, and a sterilization system to achieve automated sampling.

Benefits of technology

This improved sampling efficiency, reduced the workload of staff, and lowered the risk of contamination at the sampling point, ensuring that the clean environment was not compromised.

✦ Generated by Eureka AI based on patent content.

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Abstract

This application relates to the field of pharmaceutical technology, and in particular to a sampling system. The sampling system includes: a movable sealing plate, movably disposed at a sampling point, the sampling point having a sampling port, the movable sealing plate being able to open or close relative to the sampling port; a movable carrier, capable of moving toward or away from the sampling point; a sampling device disposed on the movable carrier and moving with the movable carrier; and a cargo tray disposed on the movable carrier. The sampling system provided by this application replaces the traditional manual sampling operation mode, significantly improving the degree of automation, thereby effectively improving sampling efficiency, reducing the workload of personnel, and also reducing the risk of sampling port contamination.
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Description

Technical Field

[0001] This application relates to the field of pharmaceutical technology, and in particular to a sampling system. Background Technology

[0002] Currently, water systems are an important part of pharmaceutical processes. The sampling points of existing water system equipment are distributed in various locations, requiring staff to go to these scattered sampling locations to collect samples. This repeated sampling by staff seriously affects the sampling efficiency. In addition, the sampling bottles are exposed to the environment. This practice can only be carried out in clean areas, and the sampling requires a very high level of environmental cleanliness. Utility Model Content

[0003] The purpose of this application is to provide a sampling system that, to a certain extent, solves the technical problem in the prior art that, during the water system sampling process, workers need to go to various scattered sampling locations, which is cumbersome and easily affects production efficiency.

[0004] This application provides a sampling system, including:

[0005] A movable sealing plate is movably disposed at a sampling point, the sampling point being provided with a sampling port, and the movable sealing plate being able to open or close relative to the sampling port;

[0006] A mobile vehicle capable of moving toward or away from the sampling point;

[0007] A sampling device is disposed on the mobile carrier and moves with the mobile carrier;

[0008] A cargo tray, which is disposed on the mobile vehicle.

[0009] In the above technical solution, the sampling system further includes a driving mechanism, which is disposed at the sampling point, and the movable sealing plate is connected to the driving mechanism.

[0010] In any of the above technical solutions, the driving mechanism further includes:

[0011] Lifting assembly;

[0012] A connecting plate, which is slidably connected to the lifting assembly;

[0013] A telescopic assembly is disposed on the connecting plate; the movable sealing plate is connected to the telescopic assembly, and the telescopic assembly can drive the movable sealing plate to move closer to or away from the sampling port.

[0014] In any of the above technical solutions, the sampling system further includes a fixed sealed chamber, which is disposed at the sampling point, and the sampling port is located inside the fixed sealed chamber.

[0015] In any of the above technical solutions, the sampling system further includes:

[0016] A first positioning element is disposed at the sampling point; the mobile vehicle is provided with a first identification device for identifying the first positioning element.

[0017] The second positioning element is disposed on the side of the sampling port; the sampling device is provided with a second identification device for identifying the second positioning element.

[0018] In any of the above technical solutions, the sampling system further includes an air shower system, which is disposed on the side of the sampling point.

[0019] In any of the above technical solutions, the sampling system further includes a packaging device, which is disposed on the mobile carrier and spaced apart from the sampling device.

[0020] In any of the above technical solutions, the carrying tray further includes a plurality of receiving slots for storing sampling bottles.

[0021] In any of the above technical solutions, the sampling system further includes a sterilization system, which is located at the sampling point and acts on the sampling port.

[0022] In any of the above technical solutions, the sampling system further includes an emission system, which is connected to the fixed sealed chamber.

[0023] Compared with the prior art, the beneficial effects of this application are as follows:

[0024] The sampling system provided in this application includes: a movable sealing plate, which is movably disposed at a sampling point, the sampling point being provided with a sampling port, and the movable sealing plate being able to open or close relative to the sampling port; a movable carrier, which is able to move toward or away from the sampling point; a sampling device, which is disposed on the movable carrier and moves with the movable carrier; and a cargo tray, which is disposed on the movable carrier.

[0025] The sampling system provided in this application replaces the traditional manual sampling operation mode, significantly improves the degree of automation, thereby effectively improving sampling efficiency, reducing the workload of staff, and reducing the risk of sampling port contamination. Attached Figure Description

[0026] To more clearly illustrate the technical solutions in the specific embodiments of this application or the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0027] Figure 1 This is a schematic diagram of the sampling system provided in the embodiments of this application;

[0028] Figure 2 Another perspective view of the sampling system provided in the embodiments of this application;

[0029] Figure 3 This is a partial structural schematic diagram of the sampling system provided in the embodiments of this application;

[0030] Figure 4 This is another schematic diagram of the sampling system provided in the embodiments of this application;

[0031] Figure 5 A schematic diagram of the open state structure of the moving sealing plate of the sampling system provided in the embodiment of this application;

[0032] Figure 6 This is another structural schematic diagram of the sampling system provided in the embodiments of this application.

[0033] Figure label:

[0034] 1-Air shower system, 2-Moving sealing plate, 3-Top-out cylinder, 4-Fixed sealing chamber, 5-Lifting slide rail, 6-Lifting cylinder, 7-Sampling port, 8-Discharge system, 9-Second positioning component, 10-First positioning component, 11-Moving carrier, 12-Sampling device, 13-Sealing device, 14-Package tray, 15-Sampling bottle. Detailed Implementation

[0035] The technical solutions of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of this application, but not all embodiments.

[0036] The components of the embodiments of this application described and shown in the accompanying drawings can be arranged and designed in a variety of different configurations. Therefore, the following detailed description of the embodiments of this application provided in the drawings is not intended to limit the scope of the claimed application, but merely to illustrate selected embodiments of the application.

[0037] Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0038] In the description of this application, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0039] In the description of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0040] The following reference Figures 1 to 6 The sampling system described in the embodiments of this application.

[0041] See Figures 1 to 6 As shown, an embodiment of this application provides a sampling system, which includes a movable sealing plate 2, a movable carrier 11, a sampling device 12, and a carrying tray 14. The movable sealing plate 2 is movably disposed at a sampling point, which has a sampling port 7. As the movable sealing plate 2 moves, it can move to the sampling port 7 and close relative to it, thus covering the port 7, or it can move away from the port 7 to expose it for sampling. The movable carrier 11 has a support platform, and the sampling device 12 is disposed on the platform. Specifically, the sampling device 12 is a multi-axis robotic arm commonly used in the prior art. The sampling device 12 has grippers capable of holding or releasing sampling bottles 15 for sampling. The sampling device 12 moves towards or away from the sampling point with the movable carrier 11 and can also reciprocate between sampling points. The carrying tray 14 is disposed on the support platform and is used to hold the sampling bottles 15. It should be noted that the sampling port 7 is equipped with a valve, preferably an electrically controlled valve or a pneumatic valve, which can be remotely controlled to open or close the valve.

[0042] Specifically, the sampling system also includes a fixed sealing chamber 4, which is located at the sampling point. The sampling port 7 is located inside the fixed sealing chamber 4. The fixed sealing chamber 4 has an opening. As the movable sealing plate 2 moves, the movable sealing plate 2 can cover the opening or leave the opening.

[0043] Furthermore, the tray 14 is flat and has multiple receiving slots arranged in a matrix. The shape of the receiving slots is adapted to the shape of the sampling bottle 15, so that the sampling bottle 15 can be stably placed in the receiving slots.

[0044] Furthermore, the sampling system also includes a drive mechanism for driving the moving sealing plate 2. The drive mechanism includes a lifting assembly, a connecting plate, and a telescopic assembly. The lifting assembly includes a lifting cylinder 6 and a lifting slide rail 5. The lifting slide rail 5 is located at the sampling point and extends vertically. The connecting plate is slidably connected to the lifting slide rail 5. The telescopic rod of the lifting cylinder 6 is connected to the connecting plate. The lifting cylinder 6 can drive the connecting plate to rise or fall vertically.

[0045] The telescopic assembly is mounted on the connecting plate, allowing it to rise or fall with the connecting plate. The telescopic assembly includes an ejector cylinder 3, which is mounted on the connecting plate. The telescopic rod of the ejector cylinder 3 is connected to the movable sealing plate 2, and the ejector cylinder 3 can drive the movable sealing plate 2 to move closer to or away from the opening of the fixed sealing chamber 4.

[0046] Furthermore, the sampling system also includes a packaging device 13, which is a multi-axis robot commonly used in the prior art. The packaging device 13 includes an operator with a twisting function, and the packaging device 13 is arranged at an interval from the sampling device 12 on the support platform.

[0047] Furthermore, the sampling system also includes a first positioning element 10 and a first identification device (not shown in the figure). The first positioning element 10 is disposed at the sampling point, and the first identification device is disposed on the mobile vehicle 11. The first identification device can identify the first positioning element 10, thereby causing the mobile vehicle 11 to move toward the sampling point. The first identification device can be a camera and the first positioning element 10 can be an identification tag, or the first identification device can be a lidar and the first positioning element 10 can be a reflector.

[0048] Furthermore, this sampling system also includes a second positioning element 9 and a second identification device (not shown in the figure). The second identification device is disposed on the sampling device 12. Preferably, the second identification device is disposed near the gripper of the sampling device 12, and the second positioning element 9 is disposed on the side of the sampling port 7 and near the sampling port 7. The second identification device can identify the second positioning element 9 to achieve positioning, so that the sampling device 12 can approach the sampling port 7. The second identification device can be a camera and the second positioning element 9 can be an identification tag, or the second identification device can be a LiDAR and the second positioning element 9 can be a reflector.

[0049] Furthermore, the sampling system also includes an air shower system 1, which is located on the side of the sampling point. Preferably, the air shower system 1 is located above the sampling point. The air shower system 1 has multiple air outlets and can deliver clean gas toward the sampling port 7, which may be, but is not limited to, compressed air, to purge the sampling port 7.

[0050] Furthermore, the sampling system also includes a sterilization system (not shown in the figure), which is located at or on the side of the sampling point. The sterilization system includes at least one steam outlet that extends into the fixed sealed chamber 4 and is positioned toward the sampling port 7. The sampling port 7 can be sterilized with steam before and / or after sampling.

[0051] Preferably, the sampling point is also equipped with a purging system (not shown in the figure). After the sampling port 7 is sterilized with steam, the purging system purges the sampling port 7 with clean compressed air and maintains positive pressure in the pipeline after purging.

[0052] Furthermore, this sampling system also includes a discharge system 8, which includes a carrier container, a connecting pipe, and a pump body. The carrier container is located inside the fixed sealed chamber 4, or the carrier container is connected to the fixed sealed chamber 4. After the sampling port 7 is sterilized with steam, a certain amount of condensate will be generated, and a certain amount of liquid will also flow out when the sampling port 7 is rinsed. After the pump body is started, the condensate can be discharged to keep the fixed sealed chamber 4 and the sampling port 7 dry.

[0053] More preferably, this sampling system is installed in a cleanroom, and sampling is completed by replacing manual sampling, thus avoiding pollution of the cleanroom environment.

[0054] When this sampling system is in operation, upon the need for sampling, the mobile carrier 11 is activated to move the sampling device 12 and the sealing device 13 to the designated sampling point. After the mobile carrier 11 is in place, the valve of the sampling port 7 is opened, and the sampling port 7 is rinsed for 1-3 minutes. After rinsing, the air shower system 1 is activated to dry the sampling port 7. The ejection cylinder 3 is activated to push the movable sealing plate 2 outward, and then the lifting cylinder 6 is activated to move the movable sealing plate 2 downward to expose the sampling port 7. After the sampling device 12 identifies the sampling port 7, it moves the sampling bottle 15 to the sampling port 7, loads a small amount of sample, and closes the valve. Then, the sampling device 12 moves back to its original position, and the sealing device 13 puts the bottle cap on the sampling bottle 15 to seal it. Then, the sampling device 12 places the sealed sampling bottle 15 on the carrying tray 14, thus completing the sampling process. The drive mechanism then moves the movable sealing plate 2 back to the closed state, shutting down the air shower system 1. Finally, the sterilization system is activated to sterilize the sampling port 7, and the resulting condensate is discharged through the drainage system 8. This process is repeated for each sampling point.

[0055] In summary, the sampling system provided in this application replaces the traditional manual sampling operation mode, significantly improves the degree of automation, thereby effectively improving sampling efficiency, reducing the workload of staff, and reducing the risk of contamination at the sampling port.

[0056] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A sampling system characterized by, include: A movable sealing plate is movably disposed at a sampling point, the sampling point being provided with a sampling port, and the movable sealing plate being able to open or close relative to the sampling port; A mobile vehicle capable of moving toward or away from the sampling point; A sampling device is disposed on the mobile carrier and moves with the mobile carrier; A cargo tray, which is disposed on the mobile vehicle.

2. The sampling system of claim 1, wherein, The sampling system also includes a drive mechanism, which is located at the sampling point, and the movable sealing plate is connected to the drive mechanism.

3. The sampling system of claim 2, wherein, The drive mechanism includes: Lifting components; A connecting plate, which is slidably connected to the lifting assembly; A telescopic assembly is disposed on the connecting plate; the movable sealing plate is connected to the telescopic assembly, and the telescopic assembly can drive the movable sealing plate to move closer to or away from the sampling port.

4. The sampling system of claim 2, wherein, The sampling system also includes a fixed sealed chamber, which is located at the sampling point, and the sampling port is located inside the fixed sealed chamber.

5. The sampling system of claim 1, wherein, The sampling system also includes: A first positioning element is disposed at the sampling point; the mobile vehicle is provided with a first identification device for identifying the first positioning element. The second positioning element is disposed on the side of the sampling port; the sampling device is provided with a second identification device for identifying the second positioning element.

6. The sampling system of claim 1, wherein, The sampling system also includes an air shower system, which is located on the side of the sampling point.

7. The sampling system of claim 1, wherein, The sampling system also includes a packaging device, which is disposed on the mobile carrier and spaced apart from the sampling device.

8. The sampling system of claim 1, wherein, The tray includes multiple compartments for storing sample bottles.

9. The sampling system of any one of claims 1 to 8, wherein, The sampling system also includes a sterilization system, which is located at the sampling point and operates at the sampling port.

10. The sampling system of claim 4, wherein, The sampling system also includes an emission system, which is connected to the fixed sealed chamber.